-
1
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
Lin J, Handschin C, Spiegelman BM (2005) Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab 1: 361-370.
-
(2005)
Cell Metab
, vol.1
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
2
-
-
33644660537
-
PGC-1 coactivators: Inducible regulators of energy metabolism in health and disease
-
Finck BN, Kelly DP (2006) PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J Clin Invest 116: 615-622.
-
(2006)
J Clin Invest
, vol.116
, pp. 615-622
-
-
Finck, B.N.1
Kelly, D.P.2
-
3
-
-
0037453718
-
Peroxisomeproliferator- activated receptor delta activates fat metabolism to prevent obesity
-
Wang YX, Lee CH, Tiep S, Yu RT, Ham J, et al. (2003) Peroxisomeproliferator- activated receptor delta activates fat metabolism to prevent obesity. Cell 113: 159-170.
-
(2003)
Cell
, vol.113
, pp. 159-170
-
-
Wang, Y.X.1
Lee, C.H.2
Tiep, S.3
Yu, R.T.4
Ham, J.5
-
4
-
-
0036633114
-
To ERR in the estrogen pathway
-
Giguere V (2002) To ERR in the estrogen pathway. Trends Endocrinol Metab 13: 220-225.
-
(2002)
Trends Endocrinol Metab
, vol.13
, pp. 220-225
-
-
Giguere, V.1
-
5
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, et al. (1999) Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 98: 115-124.
-
(1999)
Cell
, vol.98
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
Zhang, C.4
Adelmant, G.5
-
6
-
-
0038036024
-
Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells
-
St-Pierre J, Lin J, Krauss S, Tarr PT, Yang R, et al. (2003) Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells. J Biol Chem 278: 26597-26603.
-
(2003)
J Biol Chem
, vol.278
, pp. 26597-26603
-
-
St-Pierre, J.1
Lin, J.2
Krauss, S.3
Tarr, P.T.4
Yang, R.5
-
7
-
-
0035855905
-
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
-
Herzig S, Long F, Jhala US, Hedrick S, Quinn R, et al. (2001) CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature 413: 179-183.
-
(2001)
Nature
, vol.413
, pp. 179-183
-
-
Herzig, S.1
Long, F.2
Jhala, U.S.3
Hedrick, S.4
Quinn, R.5
-
8
-
-
0035855858
-
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
-
Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, et al. (2001) Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 413: 131-138.
-
(2001)
Nature
, vol.413
, pp. 131-138
-
-
Yoon, J.C.1
Puigserver, P.2
Chen, G.3
Donovan, J.4
Wu, Z.5
-
9
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
-
Lin J, Wu PH, Tarr PT, Lindenberg KS, St-Pierre J, et al. (2004) Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell 119: 121-135.
-
(2004)
Cell
, vol.119
, pp. 121-135
-
-
Lin, J.1
Wu, P.H.2
Tarr, P.T.3
Lindenberg, K.S.4
St-Pierre, J.5
-
10
-
-
21144446106
-
PGC- 1alpha deficiency causes multi-system energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis
-
Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, et al. (2005) PGC- 1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol 3: e101.
-
(2005)
PLoS Biol
, vol.e101
, pp. 3
-
-
Leone, T.C.1
Lehman, J.J.2
Finck, B.N.3
Schaeffer, P.J.4
Wende, A.R.5
-
11
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
Balaban RS, Nemoto S, Finkel T (2005) Mitochondria, oxidants, and aging. Cell 120: 483-495.
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
12
-
-
0033667705
-
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
-
Arsenijevic D, Onuma H, Pecqueur C, Raimbault S, Manning BS, et al. (2000) Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat Genet 26: 435-439.
-
(2000)
Nat Genet
, vol.26
, pp. 435-439
-
-
Arsenijevic, D.1
Onuma, H.2
Pecqueur, C.3
Raimbault, S.4
Manning, B.S.5
-
13
-
-
18244379331
-
Superoxide activates mitochondrial uncoupling proteins
-
Echtay KS, Roussel D, St-Pierre J, Jekabsons MB, Cadenas S, et al. (2002) Superoxide activates mitochondrial uncoupling proteins. Nature 415: 96-99.
-
(2002)
Nature
, vol.415
, pp. 96-99
-
-
Echtay, K.S.1
Roussel, D.2
St-Pierre, J.3
Jekabsons, M.B.4
Cadenas, S.5
-
14
-
-
33749999530
-
Suppression of reactive oxygen species and neuro degeneration by the PGC-1 transcriptional co activators
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, et al. (2006) Suppression of reactive oxygen species and neuro degeneration by the PGC-1 transcriptional co activators. Cell 127: 397-408.
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
-
15
-
-
0347989301
-
Estrogen receptor-related receptors: Orphan receptors desperately seeking a ligand
-
Horard B, Vanacker JM (2003) Estrogen receptor-related receptors: orphan receptors desperately seeking a ligand. J Mol Endocrinol 31: 349-357.
-
(2003)
J Mol Endocrinol
, vol.31
, pp. 349-357
-
-
Horard, B.1
Vanacker, J.M.2
-
16
-
-
0023857147
-
Identification of a new class of steroid hormone receptors
-
Giguere V, Yang N, Segui P, Evans RM (1988) Identification of a new class of steroid hormone receptors. Nature 331: 91-94.
-
(1988)
Nature
, vol.331
, pp. 91-94
-
-
Giguere, V.1
Yang, N.2
Segui, P.3
Evans, R.M.4
-
17
-
-
0242580188
-
Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha
-
Luo J, Sladek R, Carrier J, Bader JA, Richard D, et al. (2003) Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha. Mol Cell Biol 23: 7947-7956.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7947-7956
-
-
Luo, J.1
Sladek, R.2
Carrier, J.3
Bader, J.A.4
Richard, D.5
-
18
-
-
34247554887
-
Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma
-
Dufour CR, Wilson BJ, Huss JM, Kelly DP, Alaynick WA, et al. (2007) Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma. Cell Metab 5: 345-356.
-
(2007)
Cell Metab
, vol.5
, pp. 345-356
-
-
Dufour, C.R.1
Wilson, B.J.2
Huss, J.M.3
Kelly, D.P.4
Alaynick, W.A.5
-
19
-
-
0037174798
-
Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha
-
Huss JM, Kopp RP, Kelly DP (2002) Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha. J Biol Chem 277: 40265-40274.
-
(2002)
J Biol Chem
, vol.277
, pp. 40265-40274
-
-
Huss, J.M.1
Kopp, R.P.2
Kelly, D.P.3
-
20
-
-
0142091356
-
PPARgamma coactivator 1beta/ERR ligand 1 is an ERR protein ligand, whoseexpression induces a high-energy expenditure and antagonizes obesity
-
Kamei Y, Ohizumi H, Fujitani Y, Nemoto T, Tanaka T, et al. (2003) PPARgamma coactivator 1beta/ERR ligand 1 is an ERR protein ligand, whoseexpression induces a high-energy expenditure and antagonizes obesity. Proc Natl Acad Sci USA 100: 12378-12383.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12378-12383
-
-
Kamei, Y.1
Ohizumi, H.2
Fujitani, Y.3
Nemoto, T.4
Tanaka, T.5
-
21
-
-
34249083199
-
Sirtuins in mammals: Insights into their biological function
-
Michan S, Sinclair D (2007) Sirtuins in mammals: insights into their biological function. Biochem J 404: 1-13.
-
(2007)
Biochem J
, vol.404
, pp. 1-13
-
-
Michan, S.1
Sinclair, D.2
-
22
-
-
34547875773
-
Sirtuins: Critical regulators at the crossroads between cancer and aging
-
Saunders LR, Verdin E (2007) Sirtuins: critical regulators at the crossroads between cancer and aging. Oncogene 26: 5489-5504.
-
(2007)
Oncogene
, vol.26
, pp. 5489-5504
-
-
Saunders, L.R.1
Verdin, E.2
-
23
-
-
33745931074
-
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
-
Hallows WC, Lee S, Denu JM (2006) Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases. Proc Natl Acad Sci USA 103: 10230-10235.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 10230-10235
-
-
Hallows, W.C.1
Lee, S.2
Denu, J.M.3
-
24
-
-
33745889628
-
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
-
Schwer B, Bunkenborg J, Verdin RO, Andersen JS, Verdin E (2006) Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2. Proc Natl Acad Sci USA 103: 10224-10229.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 10224-10229
-
-
Schwer, B.1
Bunkenborg, J.2
Verdin, R.O.3
Andersen, J.S.4
Verdin, E.5
-
25
-
-
37549002891
-
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
-
Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, et al. (2007) Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Mol Cell Biol 27: 8807-8814.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 8807-8814
-
-
Lombard, D.B.1
Alt, F.W.2
Cheng, H.L.3
Bunkenborg, J.4
Streeper, R.S.5
-
26
-
-
55749084738
-
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
-
Ahn BH, Kim HS, Song S, Lee IH, Liu J, et al. (2008) A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. Proc Natl Acad Sci USA 105: 14447-14452.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14447-14452
-
-
Ahn, B.H.1
Kim, H.S.2
Song, S.3
Lee, I.H.4
Liu, J.5
-
27
-
-
70349208608
-
Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice
-
Sundaresan NR, Gupta M, Kim G, Rajamohan SB, Isbatan A, et al. (2009) Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. J Clin Invest 119: 2758-2771.
-
(2009)
J Clin Invest
, vol.119
, pp. 2758-2771
-
-
Sundaresan, N.R.1
Gupta, M.2
Kim, G.3
Rajamohan, S.B.4
Isbatan, A.5
-
28
-
-
53549105529
-
SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70
-
Sundaresan NR, Samant SA, Pillai VB, Rajamohan SB, Gupta MP (2008) SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol Cell Biol 28: 6384-6401.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6384-6401
-
-
Sundaresan, N.R.1
Samant, S.A.2
Pillai, V.B.3
Rajamohan, S.B.4
Gupta, M.P.5
-
29
-
-
51449083112
-
SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression
-
Jacobs KM, Pennington JD, Bisht KS, Aykin-Burns N, Kim HS, et al. (2008) SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression. Int J Biol Sci 4: 291-299.
-
(2008)
Int J Biol Sci
, vol.4
, pp. 291-299
-
-
Jacobs, K.M.1
Pennington, J.D.2
Bisht, K.S.3
Aykin-Burns, N.4
Kim, H.S.5
-
30
-
-
10744232772
-
Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly
-
Rose G, Dato S, Altomare K, Bellizzi D, Garasto S, et al. (2003) Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly. Exp Gerontol 38: 1065-1070.
-
(2003)
Exp Gerontol
, vol.38
, pp. 1065-1070
-
-
Rose, G.1
Dato, S.2
Altomare, K.3
Bellizzi, D.4
Garasto, S.5
-
31
-
-
19944433088
-
A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages
-
Bellizzi D, Rose G, Cavalcante P, Covello G, Dato S, et al. (2005) A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages. Genomics 85: 258-263.
-
(2005)
Genomics
, vol.85
, pp. 258-263
-
-
Bellizzi, D.1
Rose, G.2
Cavalcante, P.3
Covello, G.4
Dato, S.5
-
32
-
-
0037108799
-
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
-
Onyango P, Celic I, McCaffery JM, Boeke JD, Feinberg AP (2002) SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc Natl Acad Sci USA 99: 13653-13658.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13653-13658
-
-
Onyango, P.1
Celic, I.2
McCaffery, J.M.3
Boeke, J.D.4
Feinberg, A.P.5
-
33
-
-
0037135972
-
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
-
Schwer B, North BJ, Frye RA, Ott M, Verdin E (2002) The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. J Cell Biol 158: 647-657.
-
(2002)
J Cell Biol
, vol.158
, pp. 647-657
-
-
Schwer, B.1
North, B.J.2
Frye, R.A.3
Ott, M.4
Verdin, E.5
-
34
-
-
0034331238
-
Cloning and characterization of two mouse genes with homology to the yeast Sir2 gene
-
Yang YH, Chen YH, Zhang CY, Nimmakayalu MA, Ward DC, et al. (2000) Cloning and characterization of two mouse genes with homology to the yeast Sir2 gene. Genomics 69: 355-369.
-
(2000)
Genomics
, vol.69
, pp. 355-369
-
-
Yang, Y.H.1
Chen, Y.H.2
Zhang, C.Y.3
Nimmakayalu, M.A.4
Ward, D.C.5
-
35
-
-
17144424946
-
SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
-
Shi T, Wang F, Stieren E, Tong Q (2005) SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J Biol Chem 280: 13560-13567.
-
(2005)
J Biol Chem
, vol.280
, pp. 13560-13567
-
-
Shi, T.1
Wang, F.2
Stieren, E.3
Tong, Q.4
-
36
-
-
63749099484
-
A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein
-
Cooper HM, Huang JY, Verdin E, Spelbrink JN (2009) A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein. PLoS ONE 4: e4986.
-
(2009)
PLoS ONE
, vol.4
-
-
Cooper, H.M.1
Huang, J.Y.2
Verdin, E.3
Spelbrink, J.N.4
-
37
-
-
61449209922
-
Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3
-
Jin L, Galonek H, Israelian K, Choy W, Morrison M, et al. (2009) Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3. Protein Sci 18: 514-525.
-
(2009)
Protein Sci
, vol.18
, pp. 514-525
-
-
Jin, L.1
Galonek, H.2
Israelian, K.3
Choy, W.4
Morrison, M.5
-
38
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, et al. (1998) A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci USA 95: 2509-2514.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
-
39
-
-
33644868031
-
Estrogenrelated receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription
-
Herzog B, Cardenas J, Hall RK, Villena JA, Budge PJ, et al. (2006) Estrogenrelated receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription. J Biol Chem 281: 99-106.
-
(2006)
J Biol Chem
, vol.281
, pp. 99-106
-
-
Herzog, B.1
Cardenas, J.2
Hall, R.K.3
Villena, J.A.4
Budge, P.J.5
-
40
-
-
2442701392
-
PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3
-
Koo SH, Satoh H, Herzig S, Lee CH, Hedrick S, et al. (2004) PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nat Med 10: 530-534.
-
(2004)
Nat Med
, vol.10
, pp. 530-534
-
-
Koo, S.H.1
Satoh, H.2
Herzig, S.3
Lee, C.H.4
Hedrick, S.5
-
41
-
-
0141991324
-
Specific gene inhibition by adenovirus-mediated expression of small interfering RNA
-
Zhao LJ, Jian H, Zhu H (2003) Specific gene inhibition by adenovirus-mediated expression of small interfering RNA. Gene 316: 137-141.
-
(2003)
Gene
, vol.316
, pp. 137-141
-
-
Zhao, L.J.1
Jian, H.2
Zhu, H.3
-
42
-
-
34247259630
-
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha
-
Gerhart-Hines Z, Rodgers JT, Bare O, Lerin C, Kim SH, et al. (2007) Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. Embo J 26: 1913-1923.
-
(2007)
Embo J
, vol.26
, pp. 1913-1923
-
-
Gerhart-Hines, Z.1
Rodgers, J.T.2
Bare, O.3
Lerin, C.4
Kim, S.H.5
-
43
-
-
1542790433
-
Primary hepatocyte culture in collagen gel mixture and collagen sandwich
-
Wang YJ, Liu HL, Guo HT, Wen HW, Liu J (2004) Primary hepatocyte culture in collagen gel mixture and collagen sandwich. World J Gastroenterol 10: 699-702.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 699-702
-
-
Wang, Y.J.1
Liu, H.L.2
Guo, H.T.3
Wen, H.W.4
Liu, J.5
-
44
-
-
70349333218
-
Peroxisome proliferatoractivated receptor gamma coactivator-1alpha enhances antiproliferative activity of 59-deoxy-5-fluorouridine in cancer cells through induction of uridine phosphorylase
-
Kong X, Fan H, Liu X, Wang R, Liang J, et al. (2009) peroxisome proliferatoractivated receptor gamma coactivator-1alpha enhances antiproliferative activity of 59-deoxy-5-fluorouridine in cancer cells through induction of uridine phosphorylase. Mol Pharmacol 76: 854-860.
-
(2009)
Mol Pharmacol
, vol.76
, pp. 854-860
-
-
Kong, X.1
Fan, H.2
Liu, X.3
Wang, R.4
Liang, J.5
-
45
-
-
33747893489
-
Mutation of succinate dehydrogenase subunit C results in increased O2.-, oxidative stress, and genomic instability
-
Slane BG, Aykin-Burns N, Smith BJ, Kalen AL, Goswami PC, et al. (2006) Mutation of succinate dehydrogenase subunit C results in increased O2.-, oxidative stress, and genomic instability. Cancer Res 66: 7615-7620.
-
(2006)
Cancer Res
, vol.66
, pp. 7615-7620
-
-
Slane, B.G.1
Aykin-Burns, N.2
Smith, B.J.3
Kalen, A.L.4
Goswami, P.C.5
-
46
-
-
71849093571
-
Regulation of mitochondrial biogenesis during myogenesis
-
Remels AH, Langen RC, Schrauwen P, Schaart G, Schols AM, et al. (2009) Regulation of mitochondrial biogenesis during myogenesis. Mol Cell Endocrinol.
-
(2009)
Mol Cell Endocrinol
-
-
Remels, A.H.1
Langen, R.C.2
Schrauwen, P.3
Schaart, G.4
Schols, A.M.5
-
47
-
-
2342592545
-
The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis
-
Schreiber SN, Emter R, Hock MB, Knutti D, Cardenas J, et al. (2004) The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis. Proc Natl Acad Sci USA 101: 6472-6477.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6472-6477
-
-
Schreiber, S.N.1
Emter, R.2
Hock, M.B.3
Knutti, D.4
Cardenas, J.5
-
48
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, et al. (2005) Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434: 113-118.
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
-
49
-
-
2342477730
-
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle
-
Mootha VK, Handschin C, Arlow D, Xie X, St Pierre J, et al. (2004) Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proc Natl Acad Sci USA 101: 6570-6575.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6570-6575
-
-
Mootha, V.K.1
Handschin, C.2
Arlow, D.3
Xie, X.4
St Pierre, J.5
-
50
-
-
28544438180
-
PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: A mechanism for transcriptional control of muscle glucose metabolism
-
Wende AR, Huss JM, Schaeffer PJ, Giguere V, Kelly DP (2005) PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: a mechanism for transcriptional control of muscle glucose metabolism. Mol Cell Biol 25: 10684-10694.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 10684-10694
-
-
Wende, A.R.1
Huss, J.M.2
Schaeffer, P.J.3
Giguere, V.4
Kelly, D.P.5
-
51
-
-
10344261154
-
Mitochondrial superoxide and aging: Uncoupling-protein activity and superoxide production
-
Brand MD, Buckingham JA, Esteves TC, Green K, Lambert AJ, et al. (2004) Mitochondrial superoxide and aging: uncoupling-protein activity and superoxide production. Biochem Soc Symp. pp 203-213.
-
(2004)
Biochem Soc Symp
, pp. 203-213
-
-
Brand, M.D.1
Buckingham, J.A.2
Esteves, T.C.3
Green, K.4
Lambert, A.J.5
-
52
-
-
33845327501
-
SIRT1: Linking adaptive cellular responses to aging-associated changes in organismal physiology
-
Anastasiou D, Krek W (2006) SIRT1: linking adaptive cellular responses to aging-associated changes in organismal physiology. Physiology (Bethesda) 21: 404-410.
-
(2006)
Physiology (Bethesda)
, vol.21
, pp. 404-410
-
-
Anastasiou, D.1
Krek, W.2
-
53
-
-
33644749330
-
Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells
-
Kukidome D, Nishikawa T, Sonoda K, Imoto K, Fujisawa K, et al. (2006) Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells. Diabetes 55: 120-127.
-
(2006)
Diabetes
, vol.55
, pp. 120-127
-
-
Kukidome, D.1
Nishikawa, T.2
Sonoda, K.3
Imoto, K.4
Fujisawa, K.5
-
54
-
-
19444365211
-
PGC- 1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells
-
Valle I, Alvarez-Barrientos A, Arza E, Lamas S, Monsalve M (2005) PGC- 1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells. Cardiovasc Res 66: 562-573.
-
(2005)
Cardiovasc Res
, vol.66
, pp. 562-573
-
-
Valle, I.1
Alvarez-Barrientos, A.2
Arza, E.3
Lamas, S.4
Monsalve, M.5
-
55
-
-
34548627517
-
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
-
Yang H, Yang T, Baur JA, Perez E, Matsui T, et al. (2007) Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival. Cell 130: 1095-1107.
-
(2007)
Cell
, vol.130
, pp. 1095-1107
-
-
Yang, H.1
Yang, T.2
Baur, J.A.3
Perez, E.4
Matsui, T.5
-
56
-
-
34247271282
-
SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
-
Scher MB, Vaquero A, Reinberg D (2007) SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress. Genes Dev 21: 920-928.
-
(2007)
Genes Dev
, vol.21
, pp. 920-928
-
-
Scher, M.B.1
Vaquero, A.2
Reinberg, D.3
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