-
1
-
-
3242793327
-
Historical review: A brief history and personal retrospective of seven-transmembrane receptors
-
Lefkowitz RJ. 2004. Historical review: a brief history and personal retrospective of seven-transmembrane receptors. Trends Pharmacol. Sci. 25:413-22
-
(2004)
Trends Pharmacol. Sci
, vol.25
, pp. 413-422
-
-
Lefkowitz, R.J.1
-
3
-
-
0037044197
-
Phosphorylation-independent desensitization of G protein-coupled receptors?
-
Pao CS, Benovic JL. 2002. Phosphorylation-independent desensitization of G protein-coupled receptors? Sci. STKE 2002:PE42
-
(2002)
Sci. STKE
, vol.2002
-
-
Pao, C.S.1
Benovic, J.L.2
-
4
-
-
0141629679
-
Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases
-
Penela P, Ribas C, Mayor F Jr. 2003. Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases. Cell Signal. 15:973-81
-
(2003)
Cell Signal
, vol.15
, pp. 973-981
-
-
Penela, P.1
Ribas, C.2
Mayor Jr., F.3
-
5
-
-
0023515309
-
Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: Potential role of an analog of the retinal protein arrestin (48-kDa protein)
-
Benovic JL, Kuhn H, Weyand I, Codina J, Caron MG, Lefkowitz RJ. 1987. Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein). Proc. Natl. Acad. Sci. USA 84:8879-82
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 8879-8882
-
-
Benovic, J.L.1
Kuhn, H.2
Weyand, I.3
Codina, J.4
Caron, M.G.5
Lefkowitz, R.J.6
-
6
-
-
0021813707
-
Retinal S antigen identified as the 48K protein regulating light-dependent phosphodiesterase in rods
-
Pfister C, Chabre M, Plouet J, Tuyen VV, De Kozak Y, et al. 1985. Retinal S antigen identified as the 48K protein regulating light-dependent phosphodiesterase in rods. Science 228:891-93
-
(1985)
Science
, vol.228
, pp. 891-893
-
-
Pfister, C.1
Chabre, M.2
Plouet, J.3
Tuyen, V.V.4
De Kozak, Y.5
-
7
-
-
0025352299
-
β-Arrestin: A protein that regulates β-adrenergic receptor function
-
Lohse MJ, Benovic JL, Codina J, Caron MG, Lefkowitz RJ. 1990. β-Arrestin: a protein that regulates β-adrenergic receptor function. Science 248:1547-50
-
(1990)
Science
, vol.248
, pp. 1547-1550
-
-
Lohse, M.J.1
Benovic, J.L.2
Codina, J.3
Caron, M.G.4
Lefkowitz, R.J.5
-
8
-
-
0026730336
-
Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family
-
Attramadal H, Arriza JL, Aoki C, Dawson TM, Codina J, et al. 1992. Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family. J. Biol. Chem. 267:17882-90
-
(1992)
J. Biol. Chem
, vol.267
, pp. 17882-17890
-
-
Attramadal, H.1
Arriza, J.L.2
Aoki, C.3
Dawson, T.M.4
Codina, J.5
-
9
-
-
33947314576
-
-
Moore CAC, Milano SK, Benovic J. 2007. Regulation of receptor trafficking by GRKs and arrestins. Annu. Rev. Physiol. 69:in press
-
Moore CAC, Milano SK, Benovic J. 2007. Regulation of receptor trafficking by GRKs and arrestins. Annu. Rev. Physiol. 69:in press
-
-
-
-
10
-
-
0030967614
-
Arrestin/clathrin interaction. Localization of the clathrin binding domain of nonvisual arrestins to the carboxy terminus
-
Krupnick JG, Goodman OB, Jr., Keen JH, Benovic JL. 1997. Arrestin/clathrin interaction. Localization of the clathrin binding domain of nonvisual arrestins to the carboxy terminus. J. Biol. Chem. 272:15011-16
-
(1997)
J. Biol. Chem
, vol.272
, pp. 15011-15016
-
-
Krupnick, J.G.1
Goodman Jr., O.B.2
Keen, J.H.3
Benovic, J.L.4
-
11
-
-
0029770657
-
Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor
-
Goodman OB Jr, Krupnick JG, Santini F, Gurevich VV, Penn RB, et al. 1996. Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor. Nature 383:447-50
-
(1996)
Nature
, vol.383
, pp. 447-450
-
-
Goodman Jr, O.B.1
Krupnick, J.G.2
Santini, F.3
Gurevich, V.V.4
Penn, R.B.5
-
12
-
-
0037088608
-
β-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: Identification of a β-arrestin binding site in β2-adaptin
-
Laporte SA, Miller WE, Kim KM, Caron MG. 2002. β-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a β-arrestin binding site in β2-adaptin. J. Biol. Chem. 277:9247-54
-
(2002)
J. Biol. Chem
, vol.277
, pp. 9247-9254
-
-
Laporte, S.A.1
Miller, W.E.2
Kim, K.M.3
Caron, M.G.4
-
14
-
-
0035834775
-
β-Arrestin-mediated ADP-ribosylation factor 6 activation and β2-adrenergic receptor endocytosis
-
Claing A, Chen W, Miller WE, Vitale N, Moss J, et al. 2001. β-Arrestin-mediated ADP-ribosylation factor 6 activation and β2-adrenergic receptor endocytosis. J. Biol. Chem. 276:42509-13
-
(2001)
J. Biol. Chem
, vol.276
, pp. 42509-42513
-
-
Claing, A.1
Chen, W.2
Miller, W.E.3
Vitale, N.4
Moss, J.5
-
15
-
-
0030732503
-
β-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to β-adrenergic stimulation
-
Conner DA, Mathier MA, Mortensen RM, Christe M, Vatner SF, et al. 1997. β-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to β-adrenergic stimulation. Circ. Res. 81:1021-26
-
(1997)
Circ. Res
, vol.81
, pp. 1021-1026
-
-
Conner, D.A.1
Mathier, M.A.2
Mortensen, R.M.3
Christe, M.4
Vatner, S.F.5
-
16
-
-
0033601341
-
Enhanced morphine analgesia in mice lacking beta-arrestin 2
-
Bohn LM, Lefkowitz RJ, Gainetdinov RR, Peppel K, Caron MG, Lin FT. 1999. Enhanced morphine analgesia in mice lacking beta-arrestin 2. Science 286:2495-98
-
(1999)
Science
, vol.286
, pp. 2495-2498
-
-
Bohn, L.M.1
Lefkowitz, R.J.2
Gainetdinov, R.R.3
Peppel, K.4
Caron, M.G.5
Lin, F.T.6
-
17
-
-
0035852697
-
β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
-
Kohout TA, Lin FS, Perry SJ, Conner DA, Lefkowitz RJ. 2001. β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking. Proc. Natl. Acad. Sci. USA 98:1601-6
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1601-1606
-
-
Kohout, T.A.1
Lin, F.S.2
Perry, S.J.3
Conner, D.A.4
Lefkowitz, R.J.5
-
18
-
-
0034595860
-
Differential affinities of visual arrestin, beta arrestin 1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors
-
Oakley RH, Laporte SA, Holt JA, Caron MG, Barak LS. 2000. Differential affinities of visual arrestin, beta arrestin 1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors. J. Biol. Chem. 275:17201-10
-
(2000)
J. Biol. Chem
, vol.275
, pp. 17201-17210
-
-
Oakley, R.H.1
Laporte, S.A.2
Holt, J.A.3
Caron, M.G.4
Barak, L.S.5
-
19
-
-
0037059795
-
β-Arrestins regulate protease-activated receptor-1 desensitization but not internalization or down-regulation
-
Paing MM, Stutts AB, Kohout TA, Lefkowitz RJ, Trejo J. 2002. β-Arrestins regulate protease-activated receptor-1 desensitization but not internalization or down-regulation. J. Biol. Chem. 277:1292-300
-
(2002)
J. Biol. Chem
, vol.277
, pp. 1292-1300
-
-
Paing, M.M.1
Stutts, A.B.2
Kohout, T.A.3
Lefkowitz, R.J.4
Trejo, J.5
-
20
-
-
0033522896
-
Feedback regulation of beta-arrestin1 function by extracellular signal-regulated kinases
-
Lin FT, Miller WE, Luttrell LM, Lefkowitz RJ. 1999. Feedback regulation of beta-arrestin1 function by extracellular signal-regulated kinases. J. Biol. Chem. 274:15971-74
-
(1999)
J. Biol. Chem
, vol.274
, pp. 15971-15974
-
-
Lin, F.T.1
Miller, W.E.2
Luttrell, L.M.3
Lefkowitz, R.J.4
-
21
-
-
0037053280
-
Regulation of arrestin-3 phosphorylation by casein kinase II
-
Kim YM, Barak LS, Caron MG, Benovic JL. 2002. Regulation of arrestin-3 phosphorylation by casein kinase II. J. Biol. Chem. 277:16837-46
-
(2002)
J. Biol. Chem
, vol.277
, pp. 16837-16846
-
-
Kim, Y.M.1
Barak, L.S.2
Caron, M.G.3
Benovic, J.L.4
-
22
-
-
0037183495
-
Phosphorylation of β-arrestin2 regulates its function in internalization of β2-adrenergic receptors
-
Lin FT, Chen W, Shenoy S, Cong M, Exum ST, Lefkowitz RJ. 2002. Phosphorylation of β-arrestin2 regulates its function in internalization of β2-adrenergic receptors. Biochemistry 41:10692-99
-
(2002)
Biochemistry
, vol.41
, pp. 10692-10699
-
-
Lin, F.T.1
Chen, W.2
Shenoy, S.3
Cong, M.4
Exum, S.T.5
Lefkowitz, R.J.6
-
23
-
-
0030680131
-
Clathrin-mediated endocytosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of beta-arrestin1
-
Lin FT, Krueger KM, Kendall HE, Daaka Y, Fredericks ZL, et al. 1997. Clathrin-mediated endocytosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of beta-arrestin1. J. Biol. Chem. 272:31051-57
-
(1997)
J. Biol. Chem
, vol.272
, pp. 31051-31057
-
-
Lin, F.T.1
Krueger, K.M.2
Kendall, H.E.3
Daaka, Y.4
Fredericks, Z.L.5
-
24
-
-
0035834428
-
Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin
-
Shenoy SK, McDonald PH, Kohout TA, Lefkowitz RJ. 2001. Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin. Science 294:1307-13
-
(2001)
Science
, vol.294
, pp. 1307-1313
-
-
Shenoy, S.K.1
McDonald, P.H.2
Kohout, T.A.3
Lefkowitz, R.J.4
-
25
-
-
0037737763
-
Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination
-
Shenoy SK, Lefkowitz RJ. 2003. Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination. J. Biol. Chem. 278:14498-506
-
(2003)
J. Biol. Chem
, vol.278
, pp. 14498-14506
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
26
-
-
17144364766
-
Receptor-specific ubiquitination of beta-arrestin directs assembly and targeting of seven-transmembrane receptor signalosomes
-
Shenoy SK, Lefkowitz RJ. 2005. Receptor-specific ubiquitination of beta-arrestin directs assembly and targeting of seven-transmembrane receptor signalosomes. J. Biol. Chem. 280:15315-24
-
(2005)
J. Biol. Chem
, vol.280
, pp. 15315-15324
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
27
-
-
12344276574
-
Real-time monitoring of ubiquitination in living cells by BRET
-
Perroy J, Pontier S, Charest PG, Aubry M, Bouvier M. 2004. Real-time monitoring of ubiquitination in living cells by BRET. Nat. Methods 1:203-8
-
(2004)
Nat. Methods
, vol.1
, pp. 203-208
-
-
Perroy, J.1
Pontier, S.2
Charest, P.G.3
Aubry, M.4
Bouvier, M.5
-
28
-
-
0019000271
-
Proposed role of ATP in protein breakdown: Conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis
-
Hershko A, Ciechanover A, Heller H, Haas AL, Rose IA. 1980. Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis. Proc. Natl. Acad. Sci. USA 77:1783-86
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 1783-1786
-
-
Hershko, A.1
Ciechanover, A.2
Heller, H.3
Haas, A.L.4
Rose, I.A.5
-
29
-
-
0020478717
-
Ubiquitin-activating enzyme. Mechanism and role in protein-ubiquitin conjugation
-
Haas AL, Warms JV, Hershko A, Rose IA. 1982. Ubiquitin-activating enzyme. Mechanism and role in protein-ubiquitin conjugation. J. Biol. Chem. 257:2543-48
-
(1982)
J. Biol. Chem
, vol.257
, pp. 2543-2548
-
-
Haas, A.L.1
Warms, J.V.2
Hershko, A.3
Rose, I.A.4
-
30
-
-
0141442586
-
Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins
-
Hicke L, Dunn R. 2003. Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins. Annu. Rev. Cell Dev. Biol. 19:141-72
-
(2003)
Annu. Rev. Cell Dev. Biol
, vol.19
, pp. 141-172
-
-
Hicke, L.1
Dunn, R.2
-
31
-
-
0242721361
-
Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling
-
Shenoy SK, Lefkowitz RJ. 2003. Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling. Biochem. J. 375:503-15
-
(2003)
Biochem. J
, vol.375
, pp. 503-515
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
32
-
-
23144449208
-
Ubiquitin and ubiquitin-like proteins as multifunctional signals
-
Welchman RL, Gordon C, Mayer RJ. 2005. Ubiquitin and ubiquitin-like proteins as multifunctional signals. Nat. Rev. Mol. Cell Biol. 6:599-609
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 599-609
-
-
Welchman, R.L.1
Gordon, C.2
Mayer, R.J.3
-
33
-
-
0346655115
-
Regulated ubiquitination of proteins in GPCR-initiated signaling pathways
-
Wojcikiewicz RJ. 2004. Regulated ubiquitination of proteins in GPCR-initiated signaling pathways. Trends Pharmacol. Sci. 25:35-41
-
(2004)
Trends Pharmacol. Sci
, vol.25
, pp. 35-41
-
-
Wojcikiewicz, R.J.1
-
34
-
-
23144449789
-
Ubiquitin signalling in the NF-κB pathway
-
Chen ZJ. 2005. Ubiquitin signalling in the NF-κB pathway. Nat. Cell Biol. 7:758-65
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 758-765
-
-
Chen, Z.J.1
-
35
-
-
0242412524
-
Regulation of V2 vasopressin receptor degradation by agonist-promoted ubiquitination
-
Martin NP, Lefkowitz RJ, Shenoy SK. 2003. Regulation of V2 vasopressin receptor degradation by agonist-promoted ubiquitination. J. Biol. Chem. 278:45954-59
-
(2003)
J. Biol. Chem
, vol.278
, pp. 45954-45959
-
-
Martin, N.P.1
Lefkowitz, R.J.2
Shenoy, S.K.3
-
36
-
-
0035824563
-
Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting
-
Marchese A, Benovic JL. 2001. Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting. J. Biol. Chem. 276:45509-12
-
(2001)
J. Biol. Chem
, vol.276
, pp. 45509-45512
-
-
Marchese, A.1
Benovic, J.L.2
-
37
-
-
0242362743
-
The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
-
Marchese A, Raiborg C, Santini F, Keen JH, Stenmark H, Benovic JL. 2003. The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4. Dev. Cell 5:709-22
-
(2003)
Dev. Cell
, vol.5
, pp. 709-722
-
-
Marchese, A.1
Raiborg, C.2
Santini, F.3
Keen, J.H.4
Stenmark, H.5
Benovic, J.L.6
-
38
-
-
18144412332
-
c-Cbl mediates ubiquitination, degradation, and down-regulation of human protease-activated receptor 2
-
Jacob C, Cottrell GS, Gehringer D, Schmidlin F, Grady EF, Bunnett NW. 2005. c-Cbl mediates ubiquitination, degradation, and down-regulation of human protease-activated receptor 2. J. Biol. Chem. 280:16076-87
-
(2005)
J. Biol. Chem
, vol.280
, pp. 16076-16087
-
-
Jacob, C.1
Cottrell, G.S.2
Gehringer, D.3
Schmidlin, F.4
Grady, E.F.5
Bunnett, N.W.6
-
39
-
-
0037816235
-
Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor
-
Girnita L, Girnita A, Larsson O. 2003. Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor. Proc. Natl. Acad. Sci. USA 100:8247-52
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8247-8252
-
-
Girnita, L.1
Girnita, A.2
Larsson, O.3
-
40
-
-
21644463635
-
β-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase
-
Girnita L, Shenoy SK, Sehat B, Vasilcanu R, Girnita A, et al. 2005. β-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase. J. Biol. Chem. 280:24412-19
-
(2005)
J. Biol. Chem
, vol.280
, pp. 24412-24419
-
-
Girnita, L.1
Shenoy, S.K.2
Sehat, B.3
Vasilcanu, R.4
Girnita, A.5
-
41
-
-
28544440935
-
Regulation of Notch signalling by non-visual beta-arrestin
-
Mukherjee A, Veraksa A, Bauer A, Rosse C, Camonis J, Artavanis-Tsakonas S. 2005. Regulation of Notch signalling by non-visual beta-arrestin. Nat. Cell Biol. 7:1191-201
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 1191-1201
-
-
Mukherjee, A.1
Veraksa, A.2
Bauer, A.3
Rosse, C.4
Camonis, J.5
Artavanis-Tsakonas, S.6
-
42
-
-
24744447205
-
Arrestin-related proteins mediate pH signaling in fungi
-
Herranz S, Rodriguez JM, Bussink HJ, Sanchez-Ferrero JC, Arst HN Jr, et al. 2005. Arrestin-related proteins mediate pH signaling in fungi. Proc. Natl. Acad. Sci. USA 102:12141-46
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 12141-12146
-
-
Herranz, S.1
Rodriguez, J.M.2
Bussink, H.J.3
Sanchez-Ferrero, J.C.4
Arst Jr, H.N.5
-
44
-
-
0031438076
-
G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases
-
Luttrell LM, Daaka Y, Della Rocca GJ, Lefkowitz RJ. 1997. G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases. J. Biol. Chem. 272:31648-56
-
(1997)
J. Biol. Chem
, vol.272
, pp. 31648-31656
-
-
Luttrell, L.M.1
Daaka, Y.2
Della Rocca, G.J.3
Lefkowitz, R.J.4
-
45
-
-
0033610892
-
β-Arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor
-
Lin FT, Daaka Y, Lefkowitz RJ. 1998. β-Arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor. J. Biol. Chem. 273:31640-43
-
(1998)
J. Biol. Chem
, vol.273
, pp. 31640-31643
-
-
Lin, F.T.1
Daaka, Y.2
Lefkowitz, R.J.3
-
46
-
-
0031975838
-
Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase
-
Daaka Y, Luttrell LM, Ahn S, Della Rocca GJ, Ferguson SS, et al. 1998. Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. J. Biol. Chem. 273:685-88
-
(1998)
J. Biol. Chem
, vol.273
, pp. 685-688
-
-
Daaka, Y.1
Luttrell, L.M.2
Ahn, S.3
Della Rocca, G.J.4
Ferguson, S.S.5
-
47
-
-
0033613938
-
Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes
-
Luttrell LM, Ferguson SS, Daaka Y, Miller WE, Maudsley S, et al. 1999. Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science 283:655-61
-
(1999)
Science
, vol.283
, pp. 655-661
-
-
Luttrell, L.M.1
Ferguson, S.S.2
Daaka, Y.3
Miller, W.E.4
Maudsley, S.5
-
48
-
-
0034718604
-
The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta-arrestin-dependent scaffolding complex
-
DeFea KA, Vaughn ZD, O'Bryan EM, Nishijima D, Dery O, Bunnett NW. 2000. The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta-arrestin-dependent scaffolding complex. Proc. Natl. Acad. Sci. USA 97:11086-91
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 11086-11091
-
-
DeFea, K.A.1
Vaughn, Z.D.2
O'Bryan, E.M.3
Nishijima, D.4
Dery, O.5
Bunnett, N.W.6
-
49
-
-
0034646687
-
Beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis
-
Miller WE, Maudsley S, Ahn S, Khan KD, Luttrell LM, Lefkowitz RJ. 2000. Beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis. J. Biol. Chem. 275:11312-19
-
(2000)
J. Biol. Chem
, vol.275
, pp. 11312-11319
-
-
Miller, W.E.1
Maudsley, S.2
Ahn, S.3
Khan, K.D.4
Luttrell, L.M.5
Lefkowitz, R.J.6
-
50
-
-
0034689003
-
Beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2
-
DeFea KA, Zalevsky J, Thoma MS, Dery O, Mullins RD, Bunnett NW. 2000. Beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. J Cell Biol 148:1267-81
-
(2000)
J Cell Biol
, vol.148
, pp. 1267-1281
-
-
DeFea, K.A.1
Zalevsky, J.2
Thoma, M.S.3
Dery, O.4
Mullins, R.D.5
Bunnett, N.W.6
-
51
-
-
0035956983
-
Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds
-
Luttrell LM, Roudabush FL, Choy EW, Miller WE, Field ME, et al. 2001. Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds. Proc. Natl. Acad. Sci. USA 98:2449-54
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 2449-2454
-
-
Luttrell, L.M.1
Roudabush, F.L.2
Choy, E.W.3
Miller, W.E.4
Field, M.E.5
-
52
-
-
33646263875
-
Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and β-arrestins
-
Scott MG, Pierotti V, Storez H, Lindberg E, Thuret A, et al. 2006. Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and β-arrestins. Mol. Cell Biol. 26:3432-45
-
(2006)
Mol. Cell Biol
, vol.26
, pp. 3432-3445
-
-
Scott, M.G.1
Pierotti, V.2
Storez, H.3
Lindberg, E.4
Thuret, A.5
-
53
-
-
0037088585
-
β-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation
-
Tohgo A, Pierce KL, Choy EW, Lefkowitz RJ, Luttrell LM. 2002. β-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation. J. Biol. Chem. 277:9429-36
-
(2002)
J. Biol. Chem
, vol.277
, pp. 9429-9436
-
-
Tohgo, A.1
Pierce, K.L.2
Choy, E.W.3
Lefkowitz, R.J.4
Luttrell, L.M.5
-
54
-
-
0037458614
-
The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation
-
Tohgo A, Choy EW, Gesty-Palmer D, Pierce KL, Laporte S, et al. 2003. The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation. J. Biol. Chem. 278:6258-67
-
(2003)
J. Biol. Chem
, vol.278
, pp. 6258-6267
-
-
Tohgo, A.1
Choy, E.W.2
Gesty-Palmer, D.3
Pierce, K.L.4
Laporte, S.5
-
55
-
-
14844338481
-
β-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation
-
Barnes WG, Reiter E, Violin JD, Ren XR, Milligan G, Lefkowitz RJ. 2005. β-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation. J. Biol. Chem. 280:8041-50
-
(2005)
J. Biol. Chem
, vol.280
, pp. 8041-8050
-
-
Barnes, W.G.1
Reiter, E.2
Violin, J.D.3
Ren, X.R.4
Milligan, G.5
Lefkowitz, R.J.6
-
56
-
-
0141483377
-
A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis
-
Ge L, Ly Y, Hollenberg M, DeFea K. 2003. A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis. J. Biol. Chem. 278:34418-26
-
(2003)
J. Biol. Chem
, vol.278
, pp. 34418-34426
-
-
Ge, L.1
Ly, Y.2
Hollenberg, M.3
DeFea, K.4
-
57
-
-
15744390934
-
Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis
-
Hunton DL, Barnes WG, Kim J, Ren XR, Violin JD, et al. 2005. Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis. Mol. Pharmacol. 67:1229-36
-
(2005)
Mol. Pharmacol
, vol.67
, pp. 1229-1236
-
-
Hunton, D.L.1
Barnes, W.G.2
Kim, J.3
Ren, X.R.4
Violin, J.D.5
-
58
-
-
0037452623
-
Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference
-
Ahn S, Nelson CD, Garrison TR, Miller WE, Lefkowitz RJ. 2003. Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference. Proc. Natl. Acad. Sci. USA 100:1740-44
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1740-1744
-
-
Ahn, S.1
Nelson, C.D.2
Garrison, T.R.3
Miller, W.E.4
Lefkowitz, R.J.5
-
59
-
-
4143070533
-
Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor
-
Ahn S, Shenoy SK, Wei H, Lefkowitz RJ. 2004. Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor. J. Biol. Chem. 279:35518-25
-
(2004)
J. Biol. Chem
, vol.279
, pp. 35518-35525
-
-
Ahn, S.1
Shenoy, S.K.2
Wei, H.3
Lefkowitz, R.J.4
-
60
-
-
17644402459
-
Transduction of receptor signals by beta-arrestins
-
Lefkowitz RJ, Shenoy SK. 2005. Transduction of receptor signals by beta-arrestins. Science 308:512-17
-
(2005)
Science
, vol.308
, pp. 512-517
-
-
Lefkowitz, R.J.1
Shenoy, S.K.2
-
61
-
-
1542350042
-
Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2
-
Ahn S, Wei H, Garrison TR, Lefkowitz RJ. 2004. Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2. J. Biol. Chem. 279:7807-11
-
(2004)
J. Biol. Chem
, vol.279
, pp. 7807-7811
-
-
Ahn, S.1
Wei, H.2
Garrison, T.R.3
Lefkowitz, R.J.4
-
62
-
-
13444270337
-
Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor
-
Ren XR, Reiter E, Ahn S, Kim J, Chen W, Lefkowitz RJ. 2005. Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor. Proc. Natl. Acad. Sci. USA 102:1448-53
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1448-1453
-
-
Ren, X.R.1
Reiter, E.2
Ahn, S.3
Kim, J.4
Chen, W.5
Lefkowitz, R.J.6
-
63
-
-
33644857279
-
Beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor
-
Shenoy SK, Drake MT, Nelson CD, Houtz DA, Xiao K, et al. 2006. Beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. J. Biol. Chem. 281:1261-73
-
(2006)
J. Biol. Chem
, vol.281
, pp. 1261-1273
-
-
Shenoy, S.K.1
Drake, M.T.2
Nelson, C.D.3
Houtz, D.A.4
Xiao, K.5
-
64
-
-
33744957160
-
Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation
-
Gesty-Palmer D, Chen M, Reiter E, Ahn S, Nelson CD, et al. 2006. Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation. J. Biol. Chem. 281:10856-64
-
(2006)
J. Biol. Chem
, vol.281
, pp. 10856-10864
-
-
Gesty-Palmer, D.1
Chen, M.2
Reiter, E.3
Ahn, S.4
Nelson, C.D.5
-
65
-
-
0141811657
-
The role of a conserved region of the second intracellular loop in AT1 angiotensin receptor activation and signaling
-
Gaborik Z, Jagadeesh G, Zhang M, Spat A, Catt KJ, Hunyady L. 2003. The role of a conserved region of the second intracellular loop in AT1 angiotensin receptor activation and signaling. Endocrinology 144:2220-28
-
(2003)
Endocrinology
, vol.144
, pp. 2220-2228
-
-
Gaborik, Z.1
Jagadeesh, G.2
Zhang, M.3
Spat, A.4
Catt, K.J.5
Hunyady, L.6
-
66
-
-
0141703263
-
Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
-
Wei H, Ahn S, Shenoy SK, Karnik SS, Hunyady L, et al. 2003. Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2. Proc. Natl. Acad. Sci. USA 100:10782-87
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10782-10787
-
-
Wei, H.1
Ahn, S.2
Shenoy, S.K.3
Karnik, S.S.4
Hunyady, L.5
-
67
-
-
0036208442
-
Side-chain substitutions within angiotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors
-
Holloway AC, Qian H, Pipolo L, Ziogas J, Miura S, et al. 2002. Side-chain substitutions within angiotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors. Mol. Pharmacol. 61:768-77
-
(2002)
Mol. Pharmacol
, vol.61
, pp. 768-777
-
-
Holloway, A.C.1
Qian, H.2
Pipolo, L.3
Ziogas, J.4
Miura, S.5
-
68
-
-
33746632120
-
Identification of structural determinants for G-protein independent activation of mitogen activated protein kinases in the seventh transmembrane domain of the angiotensin II type 1 receptor
-
Yee DK, Suzuki A, Luo L, Fluharty SJ. 2006. Identification of structural determinants for G-protein independent activation of mitogen activated protein kinases in the seventh transmembrane domain of the angiotensin II type 1 receptor. Mol. Endocrinol. 20(8):1924-34
-
(2006)
Mol. Endocrinol
, vol.20
, Issue.8
, pp. 1924-1934
-
-
Yee, D.K.1
Suzuki, A.2
Luo, L.3
Fluharty, S.J.4
-
69
-
-
27844583473
-
Divergent behavioral roles of angiotensin receptor intracellular signaling cascades
-
Daniels D, Yee DK, Faulconbridge LF, Fluharty SJ. 2005. Divergent behavioral roles of angiotensin receptor intracellular signaling cascades. Endocrinology 146:5552-60
-
(2005)
Endocrinology
, vol.146
, pp. 5552-5560
-
-
Daniels, D.1
Yee, D.K.2
Faulconbridge, L.F.3
Fluharty, S.J.4
-
70
-
-
0019179135
-
Evidence that ICI 118551 is a potent, highly beta 2-selective adrenoceptor antagonist and can be used to characterize beta-adrenoceptor populations in tissues
-
O'Donnell SR, Wanstall JC. 1980. Evidence that ICI 118551 is a potent, highly beta 2-selective adrenoceptor antagonist and can be used to characterize beta-adrenoceptor populations in tissues. Life Sci. 27:671-77
-
(1980)
Life Sci
, vol.27
, pp. 671-677
-
-
O'Donnell, S.R.1
Wanstall, J.C.2
-
71
-
-
0141593597
-
Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors
-
Azzi M, Charest PG, Angers S, Rousseau G, Kohout T, et al. 2003. Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors. Proc. Natl. Acad. Sci. USA 100:11406-11
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 11406-11411
-
-
Azzi, M.1
Charest, P.G.2
Angers, S.3
Rousseau, G.4
Kohout, T.5
-
72
-
-
2542423686
-
Differential desensitization, receptor phosphorylation, beta-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7
-
Kohout TA, Nicholas SL, Perry SJ, Reinhart G, Junger S, Struthers RS. 2004. Differential desensitization, receptor phosphorylation, beta-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7. J. Biol. Chem. 279:23214-22
-
(2004)
J. Biol. Chem
, vol.279
, pp. 23214-23222
-
-
Kohout, T.A.1
Nicholas, S.L.2
Perry, S.J.3
Reinhart, G.4
Junger, S.5
Struthers, R.S.6
-
73
-
-
0037147145
-
Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation
-
Sun Y, Cheng Z, Ma L, Pei G. 2002. Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation. J. Biol. Chem. 277:49212-19
-
(2002)
J. Biol. Chem
, vol.277
, pp. 49212-49219
-
-
Sun, Y.1
Cheng, Z.2
Ma, L.3
Pei, G.4
-
74
-
-
33646446045
-
Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism
-
Jiang Q, Yan Z, Feng J. 2006. Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism. J. Neurosci. 26:4318-28
-
(2006)
J. Neurosci
, vol.26
, pp. 4318-4328
-
-
Jiang, Q.1
Yan, Z.2
Feng, J.3
-
75
-
-
0028984151
-
p493F12 kinase: A novel MAP kinase expressed in a subset of neurons in the human nervous system
-
Mohit AA, Martin JH, Miller CA. 1995. p493F12 kinase: a novel MAP kinase expressed in a subset of neurons in the human nervous system. Neuron 14:67-78
-
(1995)
Neuron
, vol.14
, pp. 67-78
-
-
Mohit, A.A.1
Martin, J.H.2
Miller, C.A.3
-
76
-
-
0034711397
-
Beta-arrestin 2: A receptor-regulated MAPK scaffold for the activation of JNK3
-
McDonald PH, Chow CW, Miller WE, Laporte SA, Field ME, et al. 2000. Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. Science 290:1574-77
-
(2000)
Science
, vol.290
, pp. 1574-1577
-
-
McDonald, P.H.1
Chow, C.W.2
Miller, W.E.3
Laporte, S.A.4
Field, M.E.5
-
77
-
-
0035958940
-
Identification of a motif in the carboxyl terminus of beta-arrestin2 responsible for activation of JNK3
-
Miller WE, McDonald PH, Cai SF, Field ME, Davis RJ, Lefkowitz RJ. 2001. Identification of a motif in the carboxyl terminus of beta-arrestin2 responsible for activation of JNK3. J. Biol. Chem. 276:27770-77
-
(2001)
J. Biol. Chem
, vol.276
, pp. 27770-27777
-
-
Miller, W.E.1
McDonald, P.H.2
Cai, S.F.3
Field, M.E.4
Davis, R.J.5
Lefkowitz, R.J.6
-
78
-
-
0037020264
-
Differential nucleocytoplasmic shuttling of beta-arrestins. Characterization of a leucine-rich nuclear export signal in beta-arrestin2
-
Scott MG, Le Rouzic E, Perianin A, Pierotti V, Enslen H, et al. 2002. Differential nucleocytoplasmic shuttling of beta-arrestins. Characterization of a leucine-rich nuclear export signal in beta-arrestin2. J. Biol. Chem. 277:37693-701
-
(2002)
J. Biol. Chem
, vol.277
, pp. 37693-37701
-
-
Scott, M.G.1
Le Rouzic, E.2
Perianin, A.3
Pierotti, V.4
Enslen, H.5
-
79
-
-
21844468001
-
Dynamic interaction between the dual specificity phosphatase MKP7 and the JNK3 scaffold protein beta-arrestin 2
-
Willoughby EA, Collins MK. 2005. Dynamic interaction between the dual specificity phosphatase MKP7 and the JNK3 scaffold protein beta-arrestin 2. J. Biol. Chem. 280:25651-58
-
(2005)
J. Biol. Chem
, vol.280
, pp. 25651-25658
-
-
Willoughby, E.A.1
Collins, M.K.2
-
80
-
-
0037821781
-
G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR
-
Miller WE, Houtz DA, Nelson CD, Kolattukudy PE, Lefkowitz RJ. 2003. G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR. J. Biol. Chem. 278:21663-71
-
(2003)
J. Biol. Chem
, vol.278
, pp. 21663-21671
-
-
Miller, W.E.1
Houtz, D.A.2
Nelson, C.D.3
Kolattukudy, P.E.4
Lefkowitz, R.J.5
-
81
-
-
33745832645
-
Kappa opioid receptor activation of p38 MAPK is GRK3- and arrestin-dependent in neurons and astrocytes
-
Bruchas MR, Macey TA, Lowe JD, Chavkin C. 2006. Kappa opioid receptor activation of p38 MAPK is GRK3- and arrestin-dependent in neurons and astrocytes. J. Biol. Chem. 281:18081-89
-
(2006)
J. Biol. Chem
, vol.281
, pp. 18081-18089
-
-
Bruchas, M.R.1
Macey, T.A.2
Lowe, J.D.3
Chavkin, C.4
-
82
-
-
0347695992
-
Beta-arrestin1 mediates insulin-like growth factor 1 (IGF-1) activation of phosphatidylinositol 3-kinase (PI3K) and anti-apoptosis
-
Povsic TJ, Kohout TA, Lefkowitz RJ. 2003. Beta-arrestin1 mediates insulin-like growth factor 1 (IGF-1) activation of phosphatidylinositol 3-kinase (PI3K) and anti-apoptosis. J. Biol. Chem. 278:51334-39
-
(2003)
J. Biol. Chem
, vol.278
, pp. 51334-51339
-
-
Povsic, T.J.1
Kohout, T.A.2
Lefkowitz, R.J.3
-
83
-
-
0037166254
-
α-Thrombin induces rapid and sustained Akt phosphorylation by β-arrestin 1-dependent and -independent mechanisms, and only the sustained Akt phosphorylation is essential for G1 phase progression
-
Goel R, Phillips-Mason PJ, Raben DM, Baldassare JJ. 2002. α-Thrombin induces rapid and sustained Akt phosphorylation by β-arrestin 1-dependent and -independent mechanisms, and only the sustained Akt phosphorylation is essential for G1 phase progression. J. Biol. Chem. 277:18640-48
-
(2002)
J. Biol. Chem
, vol.277
, pp. 18640-18648
-
-
Goel, R.1
Phillips-Mason, P.J.2
Raben, D.M.3
Baldassare, J.J.4
-
84
-
-
0036962405
-
β-Arrestin 1 couples thrombin to the rapid activation of the Akt pathway
-
Goel R, Baldassare JJ. 2002. β-Arrestin 1 couples thrombin to the rapid activation of the Akt pathway. Ann. NY Acad. Sci. 973:138-41
-
(2002)
Ann. NY Acad. Sci
, vol.973
, pp. 138-141
-
-
Goel, R.1
Baldassare, J.J.2
-
85
-
-
1342282975
-
α-Thrombin-mediated phosphatidylinositol 3-kinase activation through release of Gβγ dimers from Gαq and Gαi2
-
Goel R, Phillips-Mason PJ, Gardner A, Raben DM, Baldassare JJ. 2004. α-Thrombin-mediated phosphatidylinositol 3-kinase activation through release of Gβγ dimers from Gαq and Gαi2. J. Biol. Chem. 279:6701-10
-
(2004)
J. Biol. Chem
, vol.279
, pp. 6701-6710
-
-
Goel, R.1
Phillips-Mason, P.J.2
Gardner, A.3
Raben, D.M.4
Baldassare, J.J.5
-
86
-
-
22744449073
-
An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
-
Beaulieu JM, Sotnikova TD, Marion S, Lefkowitz RJ, Gainetdinov RR, Caron MG. 2005. An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 122:261-73
-
(2005)
Cell
, vol.122
, pp. 261-273
-
-
Beaulieu, J.M.1
Sotnikova, T.D.2
Marion, S.3
Lefkowitz, R.J.4
Gainetdinov, R.R.5
Caron, M.G.6
-
87
-
-
0022930702
-
Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism
-
Sen R, Baltimore D. 1986. Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism. Cell 47:921-28
-
(1986)
Cell
, vol.47
, pp. 921-928
-
-
Sen, R.1
Baltimore, D.2
-
88
-
-
25844459154
-
NF-κB: Linking inflammation and immunity to cancer development and progression
-
Karin M, Greten FR. 2005. NF-κB: linking inflammation and immunity to cancer development and progression. Nat. Rev. Immunol. 5:749-59
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
90
-
-
2342510314
-
Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-κB pathways
-
Gao H, Sun Y, Wu Y, Luan B, Wang Y, et al. 2004. Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-κB pathways. Mol Cell 14:303-17
-
(2004)
Mol Cell
, vol.14
, pp. 303-317
-
-
Gao, H.1
Sun, Y.2
Wu, Y.3
Luan, B.4
Wang, Y.5
-
91
-
-
29244452161
-
Beta-arrestin2 functions as a phosphorylation-regulated suppressor of UV-induced NF-κB activation
-
Luan B, Zhang Z, Wu Y, Kang J, Pei G. 2005. Beta-arrestin2 functions as a phosphorylation-regulated suppressor of UV-induced NF-κB activation. EMBO J. 24:4237-46
-
(2005)
EMBO J
, vol.24
, pp. 4237-4246
-
-
Luan, B.1
Zhang, Z.2
Wu, Y.3
Kang, J.4
Pei, G.5
-
92
-
-
25444495647
-
β-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts
-
Gesty-Palmer D, Shewy HE, Kohout TA, Luttrell LM. 2005. β-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts. J. Biol. Chem. 280:32157-67
-
(2005)
J. Biol. Chem
, vol.280
, pp. 32157-32167
-
-
Gesty-Palmer, D.1
Shewy, H.E.2
Kohout, T.A.3
Luttrell, L.M.4
-
93
-
-
30544431968
-
Beta-arrestin 2 modulates the activity of nuclear receptor RAR beta2 through activation of ERK2 kinase
-
Piu F, Gauthier NK, Wang F. 2006. Beta-arrestin 2 modulates the activity of nuclear receptor RAR beta2 through activation of ERK2 kinase. Oncogene 25:218-29
-
(2006)
Oncogene
, vol.25
, pp. 218-229
-
-
Piu, F.1
Gauthier, N.K.2
Wang, F.3
-
94
-
-
28344452845
-
A nuclear function of beta-arrestin1 in GPCR signaling: Regulation of histone acetylation and gene transcription
-
Kang J, Shi Y, Xiang B, Qu B, Su W, et al. 2005. A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription. Cell 123:833-47
-
(2005)
Cell
, vol.123
, pp. 833-847
-
-
Kang, J.1
Shi, Y.2
Xiang, B.3
Qu, B.4
Su, W.5
-
95
-
-
0028948040
-
Synthetic phosphopeptide from rhodopsin sequence induces retinal arrestin binding to photoactivated unphosphorylated rhodopsin
-
Puig J, Arendt A, Tomson FL, Abdulaeva G, Miller R, et al. 1995. Synthetic phosphopeptide from rhodopsin sequence induces retinal arrestin binding to photoactivated unphosphorylated rhodopsin. FEBS Lett. 362:185-88
-
(1995)
FEBS Lett
, vol.362
, pp. 185-188
-
-
Puig, J.1
Arendt, A.2
Tomson, F.L.3
Abdulaeva, G.4
Miller, R.5
-
96
-
-
0033545831
-
Sulfhydryl reactivity demonstrates different conformational states for arrestin, arrestin activated by a synthetic phosphopeptide, and constitutively active arrestin
-
McDowell JH, Smith WC, Miller RL, Popp MP, Arendt A, et al. 1999. Sulfhydryl reactivity demonstrates different conformational states for arrestin, arrestin activated by a synthetic phosphopeptide, and constitutively active arrestin. Biochemistry 38:6119-25
-
(1999)
Biochemistry
, vol.38
, pp. 6119-6125
-
-
McDowell, J.H.1
Smith, W.C.2
Miller, R.L.3
Popp, M.P.4
Arendt, A.5
-
97
-
-
0842331059
-
The molecular acrobatics of arrestin activation
-
Gurevich VV, Gurevich EV. 2004. The molecular acrobatics of arrestin activation. Trends Pharmacol. Sci. 25:105-11
-
(2004)
Trends Pharmacol. Sci
, vol.25
, pp. 105-111
-
-
Gurevich, V.V.1
Gurevich, E.V.2
-
98
-
-
0032568021
-
X-ray crystal structure of arrestin from bovine rod outer segments
-
Granzin J, Wilden U, Choe HW, Labahn J, Krafft B, Buldt G. 1998. X-ray crystal structure of arrestin from bovine rod outer segments. Nature 391:918-21
-
(1998)
Nature
, vol.391
, pp. 918-921
-
-
Granzin, J.1
Wilden, U.2
Choe, H.W.3
Labahn, J.4
Krafft, B.5
Buldt, G.6
-
99
-
-
0034802172
-
Crystal structure of beta-arrestin at 1.9 Å: Possible mechanism of receptor binding and membrane translocation
-
Elan M, Gurevich VV, Vishnivetskiy SA, Sigler PB, Schubert C. 2001. Crystal structure of beta-arrestin at 1.9 Å: possible mechanism of receptor binding and membrane translocation. Structure 9:869-80
-
(2001)
Structure
, vol.9
, pp. 869-880
-
-
Elan, M.1
Gurevich, V.V.2
Vishnivetskiy, S.A.3
Sigler, P.B.4
Schubert, C.5
-
100
-
-
0033574274
-
The 2.8 Å crystal structure of visual arrestin: A model for arrestin's regulation
-
Hirsch JA, Schubert C, Gurevich VV, Sigler PB. 1999. The 2.8 Å crystal structure of visual arrestin: a model for arrestin's regulation. Cell 97:257-69
-
(1999)
Cell
, vol.97
, pp. 257-269
-
-
Hirsch, J.A.1
Schubert, C.2
Gurevich, V.V.3
Sigler, P.B.4
-
101
-
-
0037066145
-
Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis
-
Milano SK, Pace HC, Kim YM, Brenner C, Benovic JL. 2002. Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis. Biochemistry 41:3321-28
-
(2002)
Biochemistry
, vol.41
, pp. 3321-3328
-
-
Milano, S.K.1
Pace, H.C.2
Kim, Y.M.3
Brenner, C.4
Benovic, J.L.5
-
102
-
-
0033597328
-
How does arrestin respond to the phosphorylated state of rhodopsin?
-
Vishnivetskiy SA, Paz CL, Schubert C, Hirsch JA, Sigler PB, Gurevich VV. 1999. How does arrestin respond to the phosphorylated state of rhodopsin? J. Biol. Chem. 274:11451-54
-
(1999)
J. Biol. Chem
, vol.274
, pp. 11451-11454
-
-
Vishnivetskiy, S.A.1
Paz, C.L.2
Schubert, C.3
Hirsch, J.A.4
Sigler, P.B.5
Gurevich, V.V.6
-
103
-
-
11244311659
-
Activation-dependent conformational changes in beta-arrestin 2
-
Xiao K, Shenoy SK, Nobles K, Lefkowitz RJ. 2004. Activation-dependent conformational changes in beta-arrestin 2. J. Biol. Chem. 279:55744-53
-
(2004)
J. Biol. Chem
, vol.279
, pp. 55744-55753
-
-
Xiao, K.1
Shenoy, S.K.2
Nobles, K.3
Lefkowitz, R.J.4
-
104
-
-
17644391412
-
Monitoring agonist-promoted conformational changes of beta-arrestin in living cells by intramolecular BRET
-
6:334-40
-
Charest PG, Terrillon S, Bouvier M. 2005. Monitoring agonist-promoted conformational changes of beta-arrestin in living cells by intramolecular BRET. EMBO Rep. 6:334-40
-
(2005)
EMBO Rep
-
-
Charest, P.G.1
Terrillon, S.2
Bouvier, M.3
-
105
-
-
8144222927
-
Receptor activity-independent recruitment of beta-arrestin2 reveals specific signalling modes
-
Terrillon S, Bouvier M. 2004. Receptor activity-independent recruitment of beta-arrestin2 reveals specific signalling modes. EMBO J. 23:3950-61
-
(2004)
EMBO J
, vol.23
, pp. 3950-3961
-
-
Terrillon, S.1
Bouvier, M.2
-
106
-
-
0028924619
-
Visual arrestin binding to rhodopsin. Diverse functional roles of positively charged residues within the phosphorylation-recognition region of arrestin
-
Gurevich VV, Benovic JL. 1995. Visual arrestin binding to rhodopsin. Diverse functional roles of positively charged residues within the phosphorylation-recognition region of arrestin. J. Biol. Chem. 270:6010-16
-
(1995)
J. Biol. Chem
, vol.270
, pp. 6010-6016
-
-
Gurevich, V.V.1
Benovic, J.L.2
-
107
-
-
0033548433
-
Targeted construction of phosphorylation-independent beta-arrestin mutants with constitutive activity in cells
-
Kovoor A, Celver J, Abdryashitov RI, Chavkin C, Gurevich VV. 1999. Targeted construction of phosphorylation-independent beta-arrestin mutants with constitutive activity in cells. J. Biol. Chem. 274:6831-34
-
(1999)
J. Biol. Chem
, vol.274
, pp. 6831-6834
-
-
Kovoor, A.1
Celver, J.2
Abdryashitov, R.I.3
Chavkin, C.4
Gurevich, V.V.5
-
108
-
-
0035909783
-
β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
-
Chen W, Hu LA, Semenov MV, Yanagawa S, Kikuchi A, et al. 2001. β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins. Proc. Natl. Acad. Sci. USA 98:14889-94
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14889-14894
-
-
Chen, W.1
Hu, L.A.2
Semenov, M.V.3
Yanagawa, S.4
Kikuchi, A.5
-
109
-
-
11144256194
-
Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2
-
Chen W, Ren XR, Nelson CD, Barak LS, Chen JK, et al. 2004. Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2. Science 306:2257-60
-
(2004)
Science
, vol.306
, pp. 2257-2260
-
-
Chen, W.1
Ren, X.R.2
Nelson, C.D.3
Barak, L.S.4
Chen, J.K.5
-
110
-
-
0042471943
-
Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling
-
Chen W, Kirkbride KC, How T, Nelson CD, Mo J, et al. 2003. Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling. Science 301:1394-97
-
(2003)
Science
, vol.301
, pp. 1394-1397
-
-
Chen, W.1
Kirkbride, K.C.2
How, T.3
Nelson, C.D.4
Mo, J.5
-
111
-
-
0242414728
-
The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor
-
Wu JH, Peppel K, Nelson CD, Lin FT, Kohout TA, et al. 2003. The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor. J. Biol. Chem. 278:44238-45
-
(2003)
J. Biol. Chem
, vol.278
, pp. 44238-44245
-
-
Wu, J.H.1
Peppel, K.2
Nelson, C.D.3
Lin, F.T.4
Kohout, T.A.5
-
113
-
-
31344463886
-
Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling
-
Wang Y, Ting Y, Teng L, Wu Y, Zhao X, Pei G. 2006. Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling. Nat. Immunol. 7:139-47
-
(2006)
Nat. Immunol
, vol.7
, pp. 139-147
-
-
Wang, Y.1
Ting, Y.2
Teng, L.3
Wu, Y.4
Zhao, X.5
Pei, G.6
-
114
-
-
0035478438
-
Heterodimerization of G-protein-coupled receptors: Pharmacology, signaling and trafficking
-
Devi LA. 2001. Heterodimerization of G-protein-coupled receptors: pharmacology, signaling and trafficking. Trends Pharmacol. Sci. 22:532-37
-
(2001)
Trends Pharmacol. Sci
, vol.22
, pp. 532-537
-
-
Devi, L.A.1
-
115
-
-
1242276192
-
Roles of G-protein-coupled receptor dimerization
-
5:30-34
-
Terrillon S, Bouvier M. 2004. Roles of G-protein-coupled receptor dimerization. EMBO Rep. 5:30-34
-
(2004)
EMBO Rep
-
-
Terrillon, S.1
Bouvier, M.2
-
116
-
-
3242730441
-
Light-dependent translocation of visual arrestin regulated by the NINAC myosin III
-
Lee SJ, Montell C. 2004. Light-dependent translocation of visual arrestin regulated by the NINAC myosin III. Neuron. 43:95-103
-
(2004)
Neuron
, vol.43
, pp. 95-103
-
-
Lee, S.J.1
Montell, C.2
-
117
-
-
0038644177
-
Light adaptation through phosphoinositide-regulated translocation of Drosophila visual arrestin
-
Lee SJ, Xu H, Kang LW, Amzel LM, Montell C. 2003. Light adaptation through phosphoinositide-regulated translocation of Drosophila visual arrestin. Neuron 39:121-32
-
(2003)
Neuron
, vol.39
, pp. 121-132
-
-
Lee, S.J.1
Xu, H.2
Kang, L.W.3
Amzel, L.M.4
Montell, C.5
-
118
-
-
3242706927
-
Myosin III illuminates the mechanism of arrestin translocation
-
Strissel KJ, Arshavsky VY. 2004. Myosin III illuminates the mechanism of arrestin translocation. Neuron 43:2-4
-
(2004)
Neuron
, vol.43
, pp. 2-4
-
-
Strissel, K.J.1
Arshavsky, V.Y.2
-
119
-
-
0033557715
-
Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding
-
Gaidarov I, Krupnick JG, Falck JR, Benovic JL, Keen JH. 1999. Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding. EMBO J. 18:871-81
-
(1999)
EMBO J
, vol.18
, pp. 871-881
-
-
Gaidarov, I.1
Krupnick, J.G.2
Falck, J.R.3
Benovic, J.L.4
Keen, J.H.5
-
120
-
-
33646942810
-
Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding
-
Milano SK, Kim YM, Stefano FP, Benovic JL, Brenner C. 2006. Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding. J. Biol. Chem. 281:9812-23
-
(2006)
J. Biol. Chem
, vol.281
, pp. 9812-9823
-
-
Milano, S.K.1
Kim, Y.M.2
Stefano, F.P.3
Benovic, J.L.4
Brenner, C.5
-
121
-
-
28844444442
-
Homo- and heterooligomerization of beta-arrestins in living cells
-
Storez H, Scott MG, Issafras H, Burtey A, Benmerah A, et al. 2005. Homo- and heterooligomerization of beta-arrestins in living cells. J. Biol. Chem. 280:40210-15
-
(2005)
J. Biol. Chem
, vol.280
, pp. 40210-40215
-
-
Storez, H.1
Scott, M.G.2
Issafras, H.3
Burtey, A.4
Benmerah, A.5
-
122
-
-
1342304089
-
Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling
-
Varadan R, Assfalg M, Haririnia A, Raasi S, Pickart C, Fushman D. 2004. Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling. J. Biol. Chem. 279:7055-63
-
(2004)
J. Biol. Chem
, vol.279
, pp. 7055-7063
-
-
Varadan, R.1
Assfalg, M.2
Haririnia, A.3
Raasi, S.4
Pickart, C.5
Fushman, D.6
-
123
-
-
33749238356
-
Opposing effects of beta-arrestin1 and beta-arrestin2 on activation and degradation of Src induced by protease-activated receptor 1
-
In press
-
Kuo FT, Lu TL, Fu HW. 2006. Opposing effects of beta-arrestin1 and beta-arrestin2 on activation and degradation of Src induced by protease-activated receptor 1. Cell Signal. In press
-
(2006)
Cell Signal
-
-
Kuo, F.T.1
Lu, T.L.2
Fu, H.W.3
-
124
-
-
0033231189
-
Identification of protein kinase C phosphorylation sites in the angiotensin II (AT1A) receptor
-
Qian H, Pipolo L, Thomas WG. 1999. Identification of protein kinase C phosphorylation sites in the angiotensin II (AT1A) receptor. Biochem. J. 343(Pt. 3):637-44
-
(1999)
Biochem. J
, vol.343
, Issue.PART. 3
, pp. 637-644
-
-
Qian, H.1
Pipolo, L.2
Thomas, W.G.3
-
125
-
-
18844411824
-
The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation
-
Milasta S, Evans NA, Ormiston L, Wilson S, Lefkowitz RJ, Milligan G. 2005. The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation. Biochem. J. 387:573-84
-
(2005)
Biochem. J
, vol.387
, pp. 573-584
-
-
Milasta, S.1
Evans, N.A.2
Ormiston, L.3
Wilson, S.4
Lefkowitz, R.J.5
Milligan, G.6
-
126
-
-
11244328357
-
Multiple independent functions of arrestins in the regulation of protease-activated receptor-2 signaling and trafficking
-
Stalheim L, Ding Y, Gullapalli A, Paing MM, Wolfe BL, et al. 2005. Multiple independent functions of arrestins in the regulation of protease-activated receptor-2 signaling and trafficking. Mol. Pharmacol. 67:78-87
-
(2005)
Mol. Pharmacol
, vol.67
, pp. 78-87
-
-
Stalheim, L.1
Ding, Y.2
Gullapalli, A.3
Paing, M.M.4
Wolfe, B.L.5
-
127
-
-
0344824657
-
Enhanced rewarding properties of morphine, but not cocaine, in β-arrestin-2 knock-out mice
-
Bohn LM, Gainetdinov RR, Sotnikova TD, Medvedev IO, Lefkowitz RJ, et al. 2003. Enhanced rewarding properties of morphine, but not cocaine, in β-arrestin-2 knock-out mice. J. Neurosci. 23:10265-73
-
(2003)
J. Neurosci
, vol.23
, pp. 10265-10273
-
-
Bohn, L.M.1
Gainetdinov, R.R.2
Sotnikova, T.D.3
Medvedev, I.O.4
Lefkowitz, R.J.5
-
128
-
-
0034619796
-
Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence
-
Bohn LM, Gainetdinov RR, Lin FT, Lefkowitz RJ, Caron MG. 2000. Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence. Nature 408:720-23
-
(2000)
Nature
, vol.408
, pp. 720-723
-
-
Bohn, L.M.1
Gainetdinov, R.R.2
Lin, F.T.3
Lefkowitz, R.J.4
Caron, M.G.5
-
129
-
-
3042659111
-
Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors
-
Wang Q, Zhao J, Brady AE, Feng J, Allen PB, et al. 2004. Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors. Science 304:1940-94
-
(2004)
Science
, vol.304
, pp. 1940-1994
-
-
Wang, Q.1
Zhao, J.2
Brady, A.E.3
Feng, J.4
Allen, P.B.5
-
130
-
-
0032899715
-
Neuroendocrine effects of dehydration in mice lacking the angiotensin AT1a receptor
-
Morris M, Li P, Callahan MF, Oliverio MI, Coffman TM, et al. 1999. Neuroendocrine effects of dehydration in mice lacking the angiotensin AT1a receptor. Hypertension 33:482-86
-
(1999)
Hypertension
, vol.33
, pp. 482-486
-
-
Morris, M.1
Li, P.2
Callahan, M.F.3
Oliverio, M.I.4
Coffman, T.M.5
-
131
-
-
25844477611
-
Composition and function of G protein-coupled receptor signalsomes controlling mitogen-activated protein kinase activity
-
Luttrell LM. 2005. Composition and function of G protein-coupled receptor signalsomes controlling mitogen-activated protein kinase activity. J. Mol. Neurosci. 26:253-64
-
(2005)
J. Mol. Neurosci
, vol.26
, pp. 253-264
-
-
Luttrell, L.M.1
-
132
-
-
0242721361
-
Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signaling
-
Shenoy SK, Lefkowitz RJ. 2003. Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signaling. Biochem. J. 375(Pt. 3):503-15
-
(2003)
Biochem. J
, vol.375
, Issue.PART. 3
, pp. 503-515
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
133
-
-
0842331059
-
The molecular acrobatics of arrestin activation
-
Gurevich VV, Gurevich EV. 2004. The molecular acrobatics of arrestin activation. Trends Pharmacol. Sci. 25(2):105-11
-
(2004)
Trends Pharmacol. Sci
, vol.25
, Issue.2
, pp. 105-111
-
-
Gurevich, V.V.1
Gurevich, E.V.2
-
135
-
-
0036177114
-
Drug efficacy at G protein-coupled receptors
-
Kenakin T. 2002. Drug efficacy at G protein-coupled receptors. Annu. Rev. Pharmacol. Toxicol. 42:349-79
-
(2002)
Annu. Rev. Pharmacol. Toxicol
, vol.42
, pp. 349-379
-
-
Kenakin, T.1
|