SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

Nature

Volumn 519, Issue 7544, 2015, Pages 477-481

  Rebsamen, Manuele ^a   Pochini, Lorena ^b   Stasyk, Taras ^c   De Araújo, Mariana E G ^c   Galluccio, Michele ^b   Kandasamy, Richard K ^a   Snijder, Berend ^a   Fauster, Astrid ^a   Rudashevskaya, Elena L ^a,e   Bruckner, Manuela ^a   Scorzoni, Stefania ^a   Filipek, Przemyslaw A ^c   Huber, Kilian V M ^a   Bigenzahn, Johannes W ^a   Heinz, Leonhard X ^a   Kraft, Claudine ^d   Bennett, Keiryn L ^a   Indiveri, Cesare ^b   Huber, Lukas A ^c   Superti Furga, Giulio ^a  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^b UNIVERSITY OF CALABRIA   (Italy)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d UNIVERSITY OF VIENNA   (Austria)

^e MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMINO ACID; AMINO ACID TRANSPORTER; ARGININE; CARRIER PROTEINS AND BINDING PROTEINS; GLUCOSE; GLUTAMINE; GUANINE NUCLEOTIDE BINDING PROTEIN; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MEMBRANE PROTEIN; METHIONYL AMINOPEPTIDASE 2; PROTEOLIPOSOME; RAG PROTEIN; SOLUTE CARRIER FAMILY 38 A9; UNCLASSIFIED DRUG; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MTOR PROTEIN, HUMAN; MULTIPROTEIN COMPLEX; NUCLEOTIDE; RRAGA PROTEIN, HUMAN; SLC38A9 PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

AMINO ACID; ENZYME ACTIVITY; GENE EXPRESSION; GLUCOSE; MEMBRANE; METABOLISM; NUTRIENT AVAILABILITY; PROTEIN; PROTEOMICS; SIGNALING;

AMINO ACID TRANSPORT; AMINO TERMINAL SEQUENCE; ARTICLE; AUTOPHAGOSOME; CELL LYSATE; CONTROLLED STUDY; FUNCTIONAL PROTEOMICS; HEK293 CELL LINE; HELA CELL LINE; K562 CELL LINE; LYSOSOME; LYSOSOME MEMBRANE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; HUMAN; METABOLISM; MOUSE;

AMINO ACID TRANSPORT SYSTEMS; AMINO ACIDS; ANIMALS; CELL LINE; HUMANS; LYSOSOMES; MICE; MONOMERIC GTP-BINDING PROTEINS; MULTIPROTEIN COMPLEXES; NUCLEOTIDES; TOR SERINE-THREONINE KINASES;

EID: 84925777835     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14107     Document Type: Article

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