Reversible effects of long-term caloric restriction protein oxidative damage

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 55, Issue 11, 2000, Pages

  Forster, M J ^a   Sohal, B H ^a   Sohal, R S ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONYL DERIVATIVE; THIOL DERIVATIVE;

AGE; ANIMAL EXPERIMENT; ARTICLE; BRAIN CORTEX; BRAIN HOMOGENATE; CALORIC INTAKE; CALORIC RESTRICTION; CONTROLLED STUDY; HEART; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 0034545209     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/55.11.B522     Document Type: Article

References (34)

1. The free radical theory of aging matures
2. Oxidative stress, caloric restriction, and aging
3. Caloric intake and aging
4. Extension of life-span by overexpression of super-oxide dismutase and catalase in Drosophila melanogaster
5. Role of caloric restriction in the prolongation of life
6. Possible mechanisms underlying the antiaging actions of caloric restriction
7. Aging and oxidative stress: Modulation by dietary restriction
8. Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice
9. Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse
10. Longevity, body weight, and neoplasia in ad libitum-fed and diet-restricted C57BL6 mice fed NIH-31 open formula diet
11. Effect of age and caloric intake on protein oxidation in different brain regions and on behavioral functions of the mouse
12. Estimating age-related changes in psychomotor function: Influence of practice and level of caloric intake in different genotypes
13. Age-related loss of cognitive function and motor skills in mice are associated with oxidative protein damage in the brain
14. Nutritional influences on aging of Fischer 344 rats: I. Physical, metabolic, and longevity characteristics
15. Dietary restriction in mice beginning at 1 year of age: Effect on lifespan and spontaneous cancer incidence
16. Modulation of age-related immune decline in mice dietarily restricted from or after midadulthood
17. Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin trapping compound N-tert-butyl-α-phenylnitrone
18. Effect of the spin-trapping compound N-tert-butyl α-phenylnitrone on protein oxidation and life span
19. Effect of chronic caloric restriction on the circadian regulation of physiological and behavioral variables in old male B6C3F1 mice
20. Carbonyl assays for determination of oxidatively modified proteins
21. Tissue sulfhydral groups
22. Mechanism of food restriction: Change of rate or change of set point?
23. Mitochondrial oxidative damage, hydrogen peroxide release and aging
24. Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria
25. Aging and proteolysis of oxidized proteins
26. Mitochondrial adenine nucleotide translocase is oxidatively modified during aging
27. Oxidative damage during aging targets mitochondrial aconitase
28. Biology of aging: Observations and principles
29. Biomarkers of aging
30. Biomarkers of age and aging
31. Toward the behavioral assessment of biological aging in the laboratory mouse: Concepts, terminology, and objectives