MTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake

Nature

Volumn 486, Issue 7404, 2012, Pages 490-495

  Yilmaz, Ömer H ^a,b,c,d   Katajisto, Pekka ^b,c,d   Lamming, Dudley W ^b,c,d   Gültekin, Yetis ^a,b,c,d   Bauer Rowe, Khristian E ^b,c,d   Sengupta, Shomit ^b,c,d   Birsoy, Kivanc ^b,c,d   Dursun, Abdulmetin ^a   Onur Yilmaz, V ^b,c,d   Selig, Martin ^a   Nielsen, G Petur ^a   Mino Kenudson, Mari ^a   Zukerberg, Lawrence R ^a   Bhan, Atul K ^a   Deshpande, Vikram ^a   Sabatini, David M ^b,c,d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; ANTIGEN; BONE STROMAL ANTIGEN 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; RAPAMYCIN; UNCLASSIFIED DRUG;

ADULT; ANTIGEN; CYTOLOGY; MAMMAL; NUTRITIONAL STATUS;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALORIC INTAKE; CALORIC RESTRICTION; CELL ACTIVATION; CELL FUNCTION; CELL RENEWAL; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PANETH CELL; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEM CELL NICHE;

ADP-RIBOSYL CYCLASE; ANIMALS; ANTIGENS, CD; CALORIC RESTRICTION; CELL COUNT; CELL DIVISION; CYCLIC ADP-RIBOSE; ENERGY INTAKE; FEMALE; GPI-LINKED PROTEINS; INTESTINES; LONGEVITY; MALE; MICE; PANETH CELLS; PARACRINE COMMUNICATION; PROTEINS; REGENERATION; SIGNAL TRANSDUCTION; SIROLIMUS; STEM CELL NICHE; STEM CELLS;

MAMMALIA;

EID: 84862994618     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11163     Document Type: Article

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