-
1
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison DE, Strong R, Sharp ZD, et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature. 2009;460:392-395.
-
(2009)
Nature.
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
-
2
-
-
79951794971
-
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice
-
Miller RA, Harrison DE, Astle CM, et al. Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci. 2011;66:191-201.
-
(2011)
J Gerontol A Biol Sci Med Sci.
, vol.66
, pp. 191-201
-
-
Miller, R.A.1
Harrison, D.E.2
Astle, C.M.3
-
3
-
-
0028360374
-
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
-
Brown EJ, Albers MW, Shin TB, et al. A mammalian protein targeted by G1-arresting rapamycin-receptor complex. Nature. 1994;369:756-758.
-
(1994)
Nature.
, vol.369
, pp. 756-758
-
-
Brown, E.J.1
Albers, M.W.2
Shin, T.B.3
-
4
-
-
78650647490
-
A comprehensive map of the mTOR signaling network
-
Caron E, Ghosh S, Matsuoka Y, et al. A comprehensive map of the mTOR signaling network. Mol Syst Biol. 2010;6:453.
-
(2010)
Mol Syst Biol.
, vol.6
, pp. 453
-
-
Caron, E.1
Ghosh, S.2
Matsuoka, Y.3
-
5
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov DD, Ali SM, Sengupta S, et al. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol Cell. 2006;22:159-168.
-
(2006)
Mol Cell.
, vol.22
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
-
8
-
-
67650825231
-
Ageing: A midlife longevity drug?
-
Kaeberlein M, Kennedy BK. Ageing: a midlife longevity drug? Nature. 2009;460:331-332.
-
(2009)
Nature.
, vol.460
, pp. 331-332
-
-
Kaeberlein, M.1
Kennedy, B.K.2
-
9
-
-
27744511769
-
Cell biology: Regulation of yeast replicative life span by TOR and Sch9 response to nutrients
-
DOI 10.1126/science.1115535
-
Kaeberlein M, Powers RW III, Steffen KK, et al. Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science. 2005;310:1193-1196. (Pubitemid 41681747)
-
(2005)
Science
, vol.310
, Issue.5751
, pp. 1193-1196
-
-
Kaeberlein, M.1
Powers III, R.W.2
Steffen, K.K.3
Westman, E.A.4
Hu, D.5
Dang, N.6
Kerr, E.O.7
Kirkland, K.T.8
Fields, S.9
Kennedy, B.K.10
-
10
-
-
33846423520
-
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
-
DOI 10.1111/j.1474-9726.2006.00267.x
-
Hansen M, Taubert S, Crawford D, Libina N, Lee SJ, Kenyon C. Lifespan extension by conditions that inhibit translation in Caenorhab-ditis elegans. Aging Cell. 2007;6:95-110. (Pubitemid 46140143)
-
(2007)
Aging Cell
, vol.6
, Issue.1
, pp. 95-110
-
-
Hansen, M.1
Taubert, S.2
Crawford, D.3
Libina, N.4
Lee, S.-J.5
Kenyon, C.6
-
11
-
-
72649091698
-
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
-
Bjedov I, Toivonen JM, Kerr F, et al. Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster. Cell Metab. 2010;11:35-46.
-
(2010)
Cell Metab.
, vol.11
, pp. 35-46
-
-
Bjedov, I.1
Toivonen, J.M.2
Kerr, F.3
-
12
-
-
0032575366
-
Glutathione measurement in human plasma. Evaluation of sample collection, storage and derivatization conditions for analysis of dansyl derivatives by HPLC
-
DOI 10.1016/S0009-8981(98)00089-8, PII S0009898198000898
-
Jones DP, Carlson JL, Samiec PS, et al. Glutathione measurement in human plasma. Evaluation of sample collection, storage and derivatiza-tion conditions for analysis of dansyl derivatives by HPLC. Clin Chim Acta. 1998;275:175-184. (Pubitemid 28323074)
-
(1998)
Clinica Chimica Acta
, vol.275
, Issue.2
, pp. 175-184
-
-
Jones, D.P.1
Carlson, J.L.2
Samiec, P.S.3
Sternberg Jr., P.4
Mody Jr., V.C.5
Reed, R.L.6
Brown, L.A.S.7
-
13
-
-
0036125494
-
Redox state of cytoplasmic thioredoxin
-
DOI 10.1016/S0076-6879(02)47036-X
-
Ritz D, Beckwith J. Redox state of cytoplasmic thioredoxin. Methods Enzymol. 2002;347:360-370. (Pubitemid 34233289)
-
(2002)
Methods in Enzymology
, vol.347
, pp. 360-370
-
-
Ritz, D.1
Beckwith, J.2
-
14
-
-
14844298802
-
Compartmental oxidation of thiol-disulphide redox couples during epidermal growth factor signalling
-
DOI 10.1042/BJ20041829
-
Halvey PJ, Watson WH, Hansen JM, Go YM, Samali A, Jones DP. Compartmental oxidation of thiol-disulphide redox couples during epidermal growth factor signalling. Biochem J. 2005;386:215-219. (Pubitemid 40343778)
-
(2005)
Biochemical Journal
, vol.386
, Issue.2
, pp. 215-219
-
-
Halvey, P.J.1
Watson, W.H.2
Hansen, J.M.3
Go, Y.-M.4
Samali, A.5
Jones, D.P.6
-
15
-
-
0842333986
-
Caloric restriction, body fat and ageing in experimental models
-
DOI 10.1111/j.1467-789X.2004.00115.x
-
Das M, Gabriely I, Barzilai N. Caloric restriction, body fat and ageing in experimental models. Obes Rev. 2004;5:13-19. (Pubitemid 38173590)
-
(2004)
Obesity Reviews
, vol.5
, Issue.1
, pp. 13-19
-
-
Das, M.1
Gabriely, I.2
Barzilai, N.3
-
16
-
-
63049094292
-
Bone growth during rapamycin therapy in young rats
-
Sanchez CP, HeYZ. Bone growth during rapamycin therapy in young rats. BMC Pediatr. 2009;9:3.
-
(2009)
BMC Pediatr.
, vol.9
, pp. 3
-
-
Sanchez, C.P.1
He, Y.Z.2
-
17
-
-
67349217986
-
Molecular mechanisms of mTOR-mediated transla-tional control
-
Ma XM, Blenis J. Molecular mechanisms of mTOR-mediated transla-tional control. Nat Rev Mol Cell Biol. 2009;10:307-318.
-
(2009)
Nat Rev Mol Cell Biol.
, vol.10
, pp. 307-318
-
-
Ma, X.M.1
Blenis, J.2
-
18
-
-
2642586352
-
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
-
DOI 10.1038/ng1362
-
Ravikumar B, Vacher C, Berger Z, et al. Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fl y and mouse models of Huntington disease. Nat Genet. 2004;36:585-595. (Pubitemid 38715985)
-
(2004)
Nature Genetics
, vol.36
, Issue.6
, pp. 585-595
-
-
Ravikumar, B.1
Vacher, C.2
Berger, Z.3
Davies, J.E.4
Luo, S.5
Oroz, L.G.6
Scaravilli, F.7
Easton, D.F.8
Duden, R.9
O'Kane, C.J.10
Rubinsztein, D.C.11
-
19
-
-
35848957932
-
Cytosolic LC3 ratio as a sensitive index of macroautophagy in isolated rat hepatocytes and H4-II-E cells
-
Karim MR, Kanazawa T, Daigaku Y, Fujimura S, Miotto G, Kadowaki M. Cytosolic LC3 ratio as a sensitive index of macroau-tophagy in isolated rat hepatocytes and H4-II-E cells. A utophagy. 2007;3:553-560. (Pubitemid 350060051)
-
(2007)
Autophagy
, vol.3
, Issue.6
, pp. 553-560
-
-
Karim, Md.R.1
Kanazawa, T.2
Daigaku, Y.3
Fujimura, S.4
Miotto, G.5
Kadowaki, M.6
-
20
-
-
8344282655
-
The role of oxidative damage and stress in aging
-
DOI 10.1016/j.mad.2004.07.009, PII S004763740400171X
-
Bokov A, Chaudhuri A, Richardson A. The role of oxidative damage and stress in aging. Mech Ageing Dev. 2004;125:811-826. (Pubitemid 39482409)
-
(2004)
Mechanisms of Ageing and Development
, vol.125
, Issue.10-11 SPEC. ISS.
, pp. 811-826
-
-
Bokov, A.1
Chaudhuri, A.2
Richardson, A.3
-
21
-
-
0037207525
-
1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin
-
DOI 10.1182/blood-2002-01-0189
-
Decker T, Hipp S, Ringshausen I, et al. Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin. Blood. 2003;101:278-285. (Pubitemid 36025919)
-
(2003)
Blood
, vol.101
, Issue.1
, pp. 278-285
-
-
Decker, T.1
Hipp, S.2
Ringshausen, I.3
Bogner, C.4
Oelsner, M.5
Schneller, F.6
Peschel, C.7
-
22
-
-
0037653628
-
Modulation of glutathione and thioredoxin systems by calorie restriction during the aging process
-
DOI 10.1016/S0531-5565(03)00005-6
-
Cho CG, Kim HJ, Chung SW, et al. Modulation of glutathione and thioredoxin systems by calorie restriction during the aging process. Exp Gerontol. 2003;38:539-548. (Pubitemid 36549040)
-
(2003)
Experimental Gerontology
, vol.38
, Issue.5
, pp. 539-548
-
-
Cho, C.G.1
Kim, H.J.2
Chung, S.W.3
Jung, K.J.4
Shim, K.H.5
Yu, B.P.6
Yodoi, J.7
Chung, H.Y.8
-
23
-
-
0041326831
-
Effects of age and caloric restriction on glutathione redox state in mice
-
DOI 10.1016/S0891-5849(03)00388-5
-
Rebrin I, Kamzalov S, Sohal RS. Effects of age and caloric restriction on glutathione redox state in mice. Free Radic Biol Med. 2003;35:626-635. (Pubitemid 37101130)
-
(2003)
Free Radical Biology and Medicine
, vol.35
, Issue.6
, pp. 626-635
-
-
Rebrin, I.1
Kamzalov, S.2
Sohal, R.S.3
-
24
-
-
33845197506
-
Effects of age and caloric intake on glutathione redox state in different brain regions of C57BL/6 and DBA/2 mice
-
DOI 10.1016/j.brainres.2006.10.040, PII S0006899306031209
-
Rebrin I, Forster MJ, Sohal RS. Effects of age and caloric intake on glutathione redox state in different brain regions of C57BL/6 and DBA/2 mice. Brain Res. 2007;1127:10-18. (Pubitemid 44854853)
-
(2007)
Brain Research
, vol.1127
, Issue.1
, pp. 10-18
-
-
Rebrin, I.1
Forster, M.J.2
Sohal, R.S.3
-
25
-
-
77949887506
-
Mammalian sirtuins: Biological insights and disease relevance
-
Haigis MC, Sinclair DA. Mammalian sirtuins: biological insights and disease relevance. Annu Rev Pathol. 2010;5:253-295.
-
(2010)
Annu Rev Pathol.
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
26
-
-
33846583673
-
SIR2: A potential target for calorie restriction mimetics
-
DOI 10.1016/j.molmed.2006.12.004, PII S1471491406002863
-
Chen D, Guarente L. SIR2: a potential target for calorie restriction mimetics. Trends Mol Med. 2007;13:64-71. (Pubitemid 46186153)
-
(2007)
Trends in Molecular Medicine
, vol.13
, Issue.2
, pp. 64-71
-
-
Chen, D.1
Guarente, L.2
-
27
-
-
45549098657
-
SirT1 regulates energy metabolism and response to caloric restriction in mice
-
Boily G, Seifert EL, Bevilacqua L, et al. SirT1 regulates energy metabolism and response to caloric restriction in mice. PLoS One. 2008;3:e1759.
-
(2008)
PLoS One.
, vol.3
-
-
Boily, G.1
Seifert, E.L.2
Bevilacqua, L.3
-
28
-
-
78651468707
-
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction
-
Hallows WC, Yu W, Smith BC, et al. Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol Cell. 2011;41:139-149.
-
(2011)
Mol Cell.
, vol.41
, pp. 139-149
-
-
Hallows, W.C.1
Yu, W.2
Smith, B.C.3
-
29
-
-
36349030394
-
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase
-
DOI 10.1074/jbc.M705488200
-
Ahuja N, Schwer B, Carobbio S, et al. Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase. J Biol Chem. 2007; 282:33583-33592. (Pubitemid 350159524)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.46
, pp. 33583-33592
-
-
Ahuja, N.1
Schwer, B.2
Carobbio, S.3
Waltregny, D.4
North, B.J.5
Castronovo, V.6
Maechler, P.7
Verdin, E.8
-
30
-
-
65249087389
-
SIRT5 deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle
-
Nakagawa T, Lomb DJ, Haigis MC, Guarente L. SIRT5 deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle. Cell. 2009;137:560-570.
-
(2009)
Cell.
, vol.137
, pp. 560-570
-
-
Nakagawa, T.1
Lomb, D.J.2
Haigis, M.C.3
Guarente, L.4
-
31
-
-
77956550868
-
Human SIRT6 promotes DNA end resection through CtIP deacetylation
-
Kaidi A, Weinert BT, Choudhary C, Jackson SP. Human SIRT6 promotes DNA end resection through CtIP deacetylation. Science. 2010;329:1348-1353.
-
(2010)
Science.
, vol.329
, pp. 1348-1353
-
-
Kaidi, A.1
Weinert, B.T.2
Choudhary, C.3
Jackson, S.P.4
-
32
-
-
58149090925
-
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span
-
Kawahara TL, Michishita E, Adler AS, et al. SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell. 2009;136:62-74.
-
(2009)
Cell.
, vol.136
, pp. 62-74
-
-
Kawahara, T.L.1
Michishita, E.2
Adler, A.S.3
-
33
-
-
64849107827
-
Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis
-
Grob A, Roussel P, Wright JE, McStay B, Hernandez-Verdun D, Sirri V. Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis. J Cell Sci. 2009;122:489-498.
-
(2009)
J Cell Sci.
, vol.122
, pp. 489-498
-
-
Grob, A.1
Roussel, P.2
Wright, J.E.3
McStay, B.4
Hernandez-Verdun, D.5
Sirri, V.6
-
35
-
-
32644476664
-
Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest
-
DOI 10.1016/j.ygyno.2005.08.053, PII S0090825805007298
-
Bae-Jump VL, Zhou C, Gehrig PA, Whang YE, Boggess JF. Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest. Gynecol Oncol. 2006;100:487-494. (Pubitemid 43246863)
-
(2006)
Gynecologic Oncology
, vol.100
, Issue.3
, pp. 487-494
-
-
Bae-Jump, V.L.1
Zhou, C.2
Gehrig, P.A.3
Whang, Y.E.4
Boggess, J.F.5
-
36
-
-
0141720388
-
Calorie restriction and aging: Review of the literature and implications for studies in humans
-
Heilbronn LK, Ravussin E. Calorie restriction and aging: review of the literature and implications for studies in humans. Am J Clin Nutr. 2003;78:361-369. (Pubitemid 39663500)
-
(2003)
American Journal of Clinical Nutrition
, vol.78
, Issue.3
, pp. 361-369
-
-
Heilbronn, L.K.1
Ravussin, E.2
-
37
-
-
78049523857
-
Caloric restriction reverses hepatic insulin resistance and steatosis in rats with low aerobic capacity
-
Bowman TA, Ramakrishnan SK, Kaw M, et al. Caloric restriction reverses hepatic insulin resistance and steatosis in rats with low aerobic capacity. Endocrinology. 2010;151:5157-5164.
-
(2010)
Endocrinology.
, vol.151
, pp. 5157-5164
-
-
Bowman, T.A.1
Ramakrishnan, S.K.2
Kaw, M.3
-
38
-
-
42449104351
-
MTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes
-
Fraenkel M, Ketzinel-Gilad M, Ariav Y, et al. mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes. Diabetes. 2008;57:945-957.
-
(2008)
Diabetes.
, vol.57
, pp. 945-957
-
-
Fraenkel, M.1
Ketzinel-Gilad, M.2
Ariav, Y.3
-
39
-
-
55849132493
-
Insulin and aging
-
Bartke A. Insulin and aging. Cell Cycle. 2008;7:3338-3343.
-
(2008)
Cell Cycle.
, vol.7
, pp. 3338-3343
-
-
Bartke, A.1
-
40
-
-
23844488868
-
The role of oxidative stress in relation to caloric restriction and longevity
-
DOI 10.1210/en.2005-0378
-
Gredilla R, Barja G. Minireview: the role of oxidative stress in relation to caloric restriction and longevity. Endocrinology. 2005;146:3713-3717. (Pubitemid 41175737)
-
(2005)
Endocrinology
, vol.146
, Issue.9
, pp. 3713-3717
-
-
Gredilla, R.1
Barja, G.2
-
41
-
-
0041695625
-
Effects of FK506 and rapamycin on generation of reactive oxygen species, nitric oxide production and nuclear factor kappa B activation in rat hepatocytes
-
DOI 10.1016/S0006-2952(03)00288-0
-
Tunon MJ, Sanchez-Campos S, Gutierrez B, Culebras JM, Gonzalez-Gallego J. Effects of FK506 and rapamycin on generation of reactive oxygen species, nitric oxide production and nuclear factor kappa B activation in rat hepatocytes. Biochem Pharmacol. 2003;66:439-445. (Pubitemid 36937029)
-
(2003)
Biochemical Pharmacology
, vol.66
, Issue.3
, pp. 439-445
-
-
Tunon, M.J.1
Sanchez-Campos, S.2
Gutierrez, B.3
Culebras, J.M.4
Gonzalez-Gallego, J.5
-
42
-
-
21844446870
-
Glutathione redox state regulates mitochondrial reactive oxygen production
-
DOI 10.1074/jbc.M500095200
-
Shen D, Dalton TP, Nebert DW, Shertzer HG. Glutathione redox state regulates mitochondrial reactive oxygen production. J Biol Chem. 2005;280:25305-25312. (Pubitemid 40962232)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.27
, pp. 25305-25312
-
-
Shen, D.1
Dalton, T.P.2
Nebert, D.W.3
Shertzer, H.G.4
-
43
-
-
0035371184
-
Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple
-
DOI 10.1016/S0891-5849(01)00480-4, PII S0891584901004804
-
Schafer FQ, Buettner GR. Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radic Biol Med. 2001;30:1191-1212. (Pubitemid 32463931)
-
(2001)
Free Radical Biology and Medicine
, vol.30
, Issue.11
, pp. 1191-1212
-
-
Schafer, F.Q.1
Buettner, G.R.2
-
44
-
-
56349118798
-
Rapamycin reverses NPM-ALK-induced glucocorticoid resistance in lymphoid tumor cells by inhibiting mTOR signaling pathway, enhancing G1 cell cycle arrest and apoptosis
-
Gu L, Gao J, Li Q, et al. Rapamycin reverses NPM-ALK-induced glucocorticoid resistance in lymphoid tumor cells by inhibiting mTOR signaling pathway, enhancing G1 cell cycle arrest and apoptosis. Leukemia. 2008;22:2091-2096.
-
(2008)
Leukemia.
, vol.22
, pp. 2091-2096
-
-
Gu, L.1
Gao, J.2
Li, Q.3
-
45
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
DOI 10.1101/gad.13.19.2570
-
Kaeberlein M, McVey M, Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 1999;13:2570-2580. (Pubitemid 29489648)
-
(1999)
Genes and Development
, vol.13
, Issue.19
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
46
-
-
80053168829
-
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
-
Burnett C, Valentini S, Cabreiro F, et al. Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature. 2011; 477:482-485.
-
(2011)
Nature.
, vol.477
, pp. 482-485
-
-
Burnett, C.1
Valentini, S.2
Cabreiro, F.3
-
47
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
DOI 10.1126/science.1099196
-
Cohen HY, Miller C, Bitterman KJ, et al. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science. 2004;305:390-392. (Pubitemid 38938153)
-
(2004)
Science
, vol.305
, Issue.5682
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
De Cabo, R.9
Sinclair, D.A.10
-
48
-
-
34447626095
-
SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction
-
DOI 10.1111/j.1474-9726.2007.00304.x
-
Wang F, Nguyen M, Qin FX, Tong Q. SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction. Aging Cell. 2007;6:505-514. (Pubitemid 47087055)
-
(2007)
Aging Cell
, vol.6
, Issue.4
, pp. 505-514
-
-
Wang, F.1
Nguyen, M.2
Qin, F.X.-F.3
Tong, Q.4
-
49
-
-
33748316536
-
SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells
-
DOI 10.1016/j.cell.2006.06.057, PII S0092867406010208
-
Haigis MC, Mostoslavsky R, Haigis KM, et al. SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells. Cell. 2006;126:941-954. (Pubitemid 44321935)
-
(2006)
Cell
, vol.126
, Issue.5
, pp. 941-954
-
-
Haigis, M.C.1
Mostoslavsky, R.2
Haigis, K.M.3
Fahie, K.4
Christodoulou, D.C.5
Murphy, AndrewJ.6
Valenzuela, D.M.7
Yancopoulos, G.D.8
Karow, M.9
Blander, G.10
Wolberger, C.11
Prolla, T.A.12
Weindruch, R.13
Alt, F.W.14
Guarente, L.15
-
50
-
-
39649100868
-
Regulation of SIRT6 protein levels by nutrient availability
-
Kanfi Y, Shalman R, Peshti V, et al. Regulation of SIRT6 protein levels by nutrient availability. FEBS Lett. 2008;582:543-548.
-
(2008)
FEBS Lett.
, vol.582
, pp. 543-548
-
-
Kanfi, Y.1
Shalman, R.2
Peshti, V.3
-
51
-
-
77954018074
-
Dietary interventions to extend life span and health span based on calorie restriction
-
Minor RK, Allard JS, Younts CM, Ward TM, de Cabo R. Dietary interventions to extend life span and health span based on calorie restriction. J Gerontol A Biol Sci Med Sci. 2010;65:695-703.
-
(2010)
J Gerontol A Biol Sci Med Sci.
, vol.65
, pp. 695-703
-
-
Minor, R.K.1
Allard, J.S.2
Younts, C.M.3
Ward, T.M.4
De Cabo, R.5
-
52
-
-
77953014263
-
The role of mTOR signaling in controlling mammalian life span: What a fungicide teaches us about longevity
-
Sharp ZD, Strong R. The role of mTOR signaling in controlling mammalian life span: what a fungicide teaches us about longevity. J Gerontol A Biol Sci Med Sci. 2010;65:580-589.
-
(2010)
J Gerontol A Biol Sci Med Sci.
, vol.65
, pp. 580-589
-
-
Sharp, Z.D.1
Strong, R.2
-
53
-
-
62049084947
-
Autophagy enhances the effi cacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells
-
Jagannath C, Lindsey DR, Dhandayuthapani S, Xu Y, Hunter RL Jr, Eissa NT. Autophagy enhances the effi cacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells. Nat Med. 2009;15:267-276.
-
(2009)
Nat Med.
, vol.15
, pp. 267-276
-
-
Jagannath, C.1
Lindsey, D.R.2
Dhandayuthapani, S.3
Xu, Y.4
Hunter, Jr.R.L.5
Eissa, N.T.6
-
54
-
-
57449093795
-
Inhibition of human immuno-defi ciency virus (HIV-1) infection in human peripheral blood leucocytes-SCID reconstituted mice by rapamycin
-
Nicoletti F, Lapenta C, Donati S, et al. Inhibition of human immuno-defi ciency virus (HIV-1) infection in human peripheral blood leucocytes-SCID reconstituted mice by rapamycin. Clin Exp Immunol. 2009;155:28-34.
-
(2009)
Clin Exp Immunol.
, vol.155
, pp. 28-34
-
-
Nicoletti, F.1
Lapenta, C.2
Donati, S.3
-
55
-
-
80052783465
-
Sirolimus-induced pneumonitis complicated by pentamidine-induced phospholipidosis in a renal transplant recipient: A case report
-
Filippone EJ, Carson JM, Beckford RA, et al. Sirolimus-induced pneumonitis complicated by pentamidine-induced phospholipidosis in a renal transplant recipient: a case report. Transplant Proc. 2011;43:2792-2797.
-
(2011)
Transplant Proc.
, vol.43
, pp. 2792-2797
-
-
Filippone, E.J.1
Carson, J.M.2
Beckford, R.A.3
|