메뉴 건너뛰기




Volumn 71, Issue , 2014, Pages 368-378

Revisiting an age-old question regarding oxidative stress

Author keywords

Age related disease; Aging; Free radicals; Life span; Longevity; Mouse models

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE PEROXIDASE; METHIONINE SULFOXIDE REDUCTASE; PEROXIREDOXIN; SUPEROXIDE DISMUTASE; THIOREDOXIN;

EID: 84899571023     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.03.038     Document Type: Review
Times cited : (63)

References (128)
  • 1
    • 84879862786 scopus 로고    scopus 로고
    • Time trends of incidence of age-associated diseases in the US elderly population: Medicare-based analysis
    • I. Akushevich, J. Kravchenko, S. Ukraintseva, K. Arbeev, and A.I. Yashin Time trends of incidence of age-associated diseases in the US elderly population: Medicare-based analysis Age Ageing 42 2013 494 500
    • (2013) Age Ageing , vol.42 , pp. 494-500
    • Akushevich, I.1    Kravchenko, J.2    Ukraintseva, S.3    Arbeev, K.4    Yashin, A.I.5
  • 2
    • 13944262937 scopus 로고    scopus 로고
    • Understanding the odd science of aging
    • T.B. L. Kirkwood Understanding the odd science of aging Cell 120 2005 437 447
    • (2005) Cell , vol.120 , pp. 437-447
    • Kirkwood, T.B.L.1
  • 4
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • D. Harman Aging: a theory based on free radical and radiation chemistry J. Gerontol. 11 1956 298 300
    • (1956) J. Gerontol. , vol.11 , pp. 298-300
    • Harman, D.1
  • 6
    • 8344282655 scopus 로고    scopus 로고
    • The role of oxidative damage and stress in aging
    • A. Bokov, A. Chaudhuri, and A. Richardson The role of oxidative damage and stress in aging Mech. Ageing Dev. 125 2004 811 826
    • (2004) Mech. Ageing Dev. , vol.125 , pp. 811-826
    • Bokov, A.1    Chaudhuri, A.2    Richardson, A.3
  • 7
    • 75149165994 scopus 로고    scopus 로고
    • Update on the oxidative stress theory of aging: Does oxidative stress play a role in aging or healthy aging?
    • A.B. Salmon, A. Richardson, and V.I. Pérez Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging? Free Radic. Biol. Med. 48 2010 642 655
    • (2010) Free Radic. Biol. Med. , vol.48 , pp. 642-655
    • Salmon, A.B.1    Richardson, A.2    Pérez, V.I.3
  • 10
    • 0033396970 scopus 로고    scopus 로고
    • Fundamental aspects of reactive oxygen species, or whats the matter with oxygen?
    • I. Fridovich Fundamental aspects of reactive oxygen species, or whats the matter with oxygen? Ann. N. Y. Acad. Sci. 893 1999 13 18
    • (1999) Ann. N. Y. Acad. Sci. , vol.893 , pp. 13-18
    • Fridovich, I.1
  • 11
    • 0017831243 scopus 로고
    • Glutathione peroxidase and hydroperoxides
    • A.L. Tappel Glutathione peroxidase and hydroperoxides Methods Enzymol. 52 1978 506 513
    • (1978) Methods Enzymol. , vol.52 , pp. 506-513
    • Tappel, A.L.1
  • 12
    • 0014819568 scopus 로고
    • Catalase: Physical and chemical properties, mechanism of catalysis, and physiological role
    • A. Deisseroth, and A.L. Dounce Catalase: physical and chemical properties, mechanism of catalysis, and physiological role Physiol. Rev. 50 1970 319 375
    • (1970) Physiol. Rev. , vol.50 , pp. 319-375
    • Deisseroth, A.1    Dounce, A.L.2
  • 14
    • 0035029131 scopus 로고    scopus 로고
    • Properties and biological activities of thioredoxins
    • G. Powis, and W.R. Montfort Properties and biological activities of thioredoxins Annu. Rev. Pharmacol. Toxicol. 41 2001 261 295
    • (2001) Annu. Rev. Pharmacol. Toxicol. , vol.41 , pp. 261-295
    • Powis, G.1    Montfort, W.R.2
  • 16
    • 0032621442 scopus 로고    scopus 로고
    • Deficiency in superoxide dismutases shortens life span of yeast cells
    • J. Wawryn, A. Krzepilko, A. Myszka, and T. Bilinski Deficiency in superoxide dismutases shortens life span of yeast cells Acta Biochim. Pol. 46 1999 249 253
    • (1999) Acta Biochim. Pol. , vol.46 , pp. 249-253
    • Wawryn, J.1    Krzepilko, A.2    Myszka, A.3    Bilinski, T.4
  • 17
    • 15844429977 scopus 로고    scopus 로고
    • Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae: Mitochondrial production of toxic oxygen species in vivo
    • V.D. Longo, E.B. Gralla, and J.S. Valentine Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae: mitochondrial production of toxic oxygen species in vivo J. Biol. Chem. 271 1996 12275 12280
    • (1996) J. Biol. Chem. , vol.271 , pp. 12275-12280
    • Longo, V.D.1    Gralla, E.B.2    Valentine, J.S.3
  • 18
    • 1642491749 scopus 로고    scopus 로고
    • Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae
    • P. Fabrizio, S.D. Pletcher, N. Minois, J.W. Vaupel, and V.D. Longo Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae FEBS Lett. 557 2004 136 142
    • (2004) FEBS Lett. , vol.557 , pp. 136-142
    • Fabrizio, P.1    Pletcher, S.D.2    Minois, N.3    Vaupel, J.W.4    Longo, V.D.5
  • 19
    • 0037683664 scopus 로고    scopus 로고
    • Mnsod overexpression extends the yeast chronological (G(0)) life span but acts independently of Sir2p histone deacetylase to shorten the replicative life span of dividing cells
    • N. Harris, V. Costa, M. MacLean, M. Mollapour, P. Moradas-Ferreira, and P.W. Piper Mnsod overexpression extends the yeast chronological (G(0)) life span but acts independently of Sir2p histone deacetylase to shorten the replicative life span of dividing cells Free Radic. Biol. Med. 34 2003 1599 1606
    • (2003) Free Radic. Biol. Med. , vol.34 , pp. 1599-1606
    • Harris, N.1    Costa, V.2    Maclean, M.3    Mollapour, M.4    Moradas-Ferreira, P.5    Piper, P.W.6
  • 21
    • 9644262490 scopus 로고    scopus 로고
    • Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae
    • M.H. Barros, B. Bandy, E.B. Tahara, and A.J. Kowaltowski Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae J. Biol. Chem. 279 2004 49883 49888
    • (2004) J. Biol. Chem. , vol.279 , pp. 49883-49888
    • Barros, M.H.1    Bandy, B.2    Tahara, E.B.3    Kowaltowski, A.J.4
  • 24
    • 0037438948 scopus 로고    scopus 로고
    • No increase in lifespan in Caenorhabditis elegans upon treatment with the superoxide dismutase mimetic EUK-8
    • M. Keaney, and D. Gems No increase in lifespan in Caenorhabditis elegans upon treatment with the superoxide dismutase mimetic EUK-8 Free Radic. Biol. Med. 34 2003 277 282
    • (2003) Free Radic. Biol. Med. , vol.34 , pp. 277-282
    • Keaney, M.1    Gems, D.2
  • 26
    • 57749095081 scopus 로고    scopus 로고
    • Against the oxidative damage theory of aging: Superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans
    • R. Doonan, J.J. McElwee, F. Matthijssens, G.A. Walker, K. Houthoofd, P. Back, A. Matscheski, J.R. Vanfleteren, and D. Gems Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans Genes Dev. 22 2008 3236 3241
    • (2008) Genes Dev. , vol.22 , pp. 3236-3241
    • Doonan, R.1    McElwee, J.J.2    Matthijssens, F.3    Walker, G.A.4    Houthoofd, K.5    Back, P.6    Matscheski, A.7    Vanfleteren, J.R.8    Gems, D.9
  • 27
    • 61449184625 scopus 로고    scopus 로고
    • Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans
    • J.M. Van Raamsdonk, and S. Hekimi Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans PLoS Genet. 5 2009 e1000361
    • (2009) PLoS Genet. , vol.5 , pp. 1000361
    • Van Raamsdonk, J.M.1    Hekimi, S.2
  • 28
    • 84862832312 scopus 로고    scopus 로고
    • Methionine sulfoxide reductase B in the endoplasmic reticulum is critical for stress resistance and aging in Drosophila
    • D.-H. Lim, J.Y. Han, J.-R. Kim, Y.S. Lee, and H.-Y. Kim Methionine sulfoxide reductase B in the endoplasmic reticulum is critical for stress resistance and aging in Drosophila Biochem. Biophys. Res. Commun. 419 2012 20 26
    • (2012) Biochem. Biophys. Res. Commun. , vol.419 , pp. 20-26
    • Lim, D.-H.1    Han, J.Y.2    Kim, J.-R.3    Lee, Y.S.4    Kim, H.-Y.5
  • 29
    • 0037358363 scopus 로고    scopus 로고
    • Does overexpression of Cu,Zn-SOD extend life span in Drosophila melanogaster?
    • W.C. Orr, and R.S. Sohal Does overexpression of Cu,Zn-SOD extend life span in Drosophila melanogaster? Exp. Gerontol. 38 2003 227 230
    • (2003) Exp. Gerontol. , vol.38 , pp. 227-230
    • Orr, W.C.1    Sohal, R.S.2
  • 32
    • 0032908347 scopus 로고    scopus 로고
    • FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies
    • J. Sun, and J. Tower FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies Mol. Cell. Biol. 19 1999 216 228
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 216-228
    • Sun, J.1    Tower, J.2
  • 33
    • 0032844257 scopus 로고    scopus 로고
    • Overexpression of glutathione reductase extends survival in transgenic Drosophila melanogaster under hyperoxia but not normoxia
    • R.J. Mockett, R.S. Sohal, and W.C. Orr Overexpression of glutathione reductase extends survival in transgenic Drosophila melanogaster under hyperoxia but not normoxia FASEB J 13 1999 1733 1742
    • (1999) FASEB J , vol.13 , pp. 1733-1742
    • Mockett, R.J.1    Sohal, R.S.2    Orr, W.C.3
  • 34
    • 27444442915 scopus 로고    scopus 로고
    • Enhanced catabolism of mitochondrial superoxide/hydrogen peroxide and aging in transgenic Drosophila
    • A.C. Bayne, R.J. Mockett, W.C. Orr, and R.S. Sohal Enhanced catabolism of mitochondrial superoxide/hydrogen peroxide and aging in transgenic Drosophila Biochem. J. 391 2005 277 284
    • (2005) Biochem. J. , vol.391 , pp. 277-284
    • Bayne, A.C.1    Mockett, R.J.2    Orr, W.C.3    Sohal, R.S.4
  • 35
    • 0037438869 scopus 로고    scopus 로고
    • Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevity
    • R.J. Mockett, A.C. Bayne, L.K. Kwong, W.C. Orr, and R.S. Sohal Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevity Free Radic. Biol. Med. 34 2003 207 217
    • (2003) Free Radic. Biol. Med. , vol.34 , pp. 207-217
    • Mockett, R.J.1    Bayne, A.C.2    Kwong, L.K.3    Orr, W.C.4    Sohal, R.S.5
  • 38
    • 33646344248 scopus 로고    scopus 로고
    • Phenotypes of mice lacking extracellular superoxide dismutase and copper- and zinc-containing superoxide dismutase
    • M.-L. Sentman, M. Granström, H. Jakobson, A. Reaume, S. Basu, and S.L. Marklund Phenotypes of mice lacking extracellular superoxide dismutase and copper- and zinc-containing superoxide dismutase J. Biol. Chem. 281 2006 6904 6909
    • (2006) J. Biol. Chem. , vol.281 , pp. 6904-6909
    • Sentman, M.-L.1    Granström, M.2    Jakobson, H.3    Reaume, A.4    Basu, S.5    Marklund, S.L.6
  • 40
    • 75149126964 scopus 로고    scopus 로고
    • Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity
    • Y. Zhang, Y. Ikeno, W. Qi, A. Chaudhuri, Y. Li, A. Bokov, S.R. Thorpe, J.W. Baynes, C. Epstein, A. Richardson, and H. Van Remmen Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity J. Gerontol., Ser. A 64 2009 1212 1220
    • (2009) J. Gerontol., Ser. A , vol.64 , pp. 1212-1220
    • Zhang, Y.1    Ikeno, Y.2    Qi, W.3    Chaudhuri, A.4    Li, Y.5    Bokov, A.6    Thorpe, S.R.7    Baynes, J.W.8    Epstein, C.9    Richardson, A.10    Van Remmen, H.11
  • 45
    • 70349693474 scopus 로고    scopus 로고
    • Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span
    • A.B. Salmon, V.I. Pérez, A. Bokov, A. Jernigan, G. Kim, H. Zhao, R.L. Levine, and A. Richardson Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span FASEB J 23 2009 3601 3608
    • (2009) FASEB J , vol.23 , pp. 3601-3608
    • Salmon, A.B.1    Pérez, V.I.2    Bokov, A.3    Jernigan, A.4    Kim, G.5    Zhao, H.6    Levine, R.L.7    Richardson, A.8
  • 49
    • 0032813103 scopus 로고    scopus 로고
    • Age-related cochlear hair cell loss is enhanced in mice lacking copper/zinc superoxide dismutase
    • S.L. McFadden, D. Ding, A.G. Reaume, D.G. Flood, and R.J. Salvi Age-related cochlear hair cell loss is enhanced in mice lacking copper/zinc superoxide dismutase Neurobiol. Aging 20 1999 1 8
    • (1999) Neurobiol. Aging , vol.20 , pp. 1-8
    • McFadden, S.L.1    Ding, D.2    Reaume, A.G.3    Flood, D.G.4    Salvi, R.J.5
  • 50
    • 11844297408 scopus 로고    scopus 로고
    • Effects of variation in superoxide dismutases (SOD) on oxidative stress and apoptosis in lens epithelium
    • V.N. Reddy, E. Kasahara, M. Hiraoka, L.R. Lin, and Y.S. Ho Effects of variation in superoxide dismutases (SOD) on oxidative stress and apoptosis in lens epithelium Exp. Eye Res. 79 2004 859 868
    • (2004) Exp. Eye Res. , vol.79 , pp. 859-868
    • Reddy, V.N.1    Kasahara, E.2    Hiraoka, M.3    Lin, L.R.4    Ho, Y.S.5
  • 51
    • 0034006162 scopus 로고    scopus 로고
    • Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice
    • T.T. Huang, E.J. Carlson, A.M. Gillespie, Y. Shi, and C.J. Epstein Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice J. Gerontol., Ser. A 55 2000 B5 9
    • (2000) J. Gerontol., Ser. A , vol.55 , pp. 5-9
    • Huang, T.T.1    Carlson, E.J.2    Gillespie, A.M.3    Shi, Y.4    Epstein, C.J.5
  • 52
  • 54
    • 33846345418 scopus 로고    scopus 로고
    • Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase
    • D. Hu, P. Cao, E. Thiels, C.T. Chu, G.Y. Wu, T.D. Oury, and E. Klann Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase Neurobiol. Learn. Mem. 87 2007 372 384
    • (2007) Neurobiol. Learn. Mem. , vol.87 , pp. 372-384
    • Hu, D.1    Cao, P.2    Thiels, E.3    Chu, C.T.4    Wu, G.Y.5    Oury, T.D.6    Klann, E.7
  • 59
    • 0022517746 scopus 로고
    • The retardation of aging in mice by dietary restriction: Longevity, cancer, immunity and lifetime energy intake
    • R. Weindruch, R.L. Walford, S. Fligiel, and D. Guthrie The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake J. Nutr. 116 1986 641 654
    • (1986) J. Nutr. , vol.116 , pp. 641-654
    • Weindruch, R.1    Walford, R.L.2    Fligiel, S.3    Guthrie, D.4
  • 60
    • 40649109044 scopus 로고    scopus 로고
    • Age-related cardiac muscle sarcopenia: Combining experimental and mathematical modeling to identify mechanisms
    • J. Lin, E.F. Lopez, Y. Jin, H. Van Remmen, T. Bauch, H.-C. Han, and M.L. Lindsey Age-related cardiac muscle sarcopenia: combining experimental and mathematical modeling to identify mechanisms Exp. Gerontol. 43 2008 296 306
    • (2008) Exp. Gerontol. , vol.43 , pp. 296-306
    • Lin, J.1    Lopez, E.F.2    Jin, Y.3    Van Remmen, H.4    Bauch, T.5    Han, H.-C.6    Lindsey, M.L.7
  • 63
    • 33746875150 scopus 로고    scopus 로고
    • Do long-lived mutant and calorie-restricted mice share common anti-aging mechanisms? - A pathological point of view
    • Y. Ikeno, C. Lew, L. Cortez, C. Webb, S. Lee, and G. Hubbard Do long-lived mutant and calorie-restricted mice share common anti-aging mechanisms? - a pathological point of view AGE 28 2006 163 171
    • (2006) AGE , vol.28 , pp. 163-171
    • Ikeno, Y.1    Lew, C.2    Cortez, L.3    Webb, C.4    Lee, S.5    Hubbard, G.6
  • 67
    • 33646922865 scopus 로고    scopus 로고
    • Reduction in mitochondrial superoxide dismutase modulates Alzheimers disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice
    • L. Esposito, J. Raber, L. Kekonius, F. Yan, G.-Q. Yu, N. Bien-Ly, J. Puoliväli, K. Scearce-Levie, E. Masliah, and L. Mucke Reduction in mitochondrial superoxide dismutase modulates Alzheimers disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice J. Neurosci. 26 2006 5167 5179
    • (2006) J. Neurosci. , vol.26 , pp. 5167-5179
    • Esposito, L.1    Raber, J.2    Kekonius, L.3    Yan, F.4    Yu, G.-Q.5    Bien-Ly, N.6    Puoliväli, J.7    Scearce-Levie, K.8    Masliah, E.9    Mucke, L.10
  • 68
    • 51349087228 scopus 로고    scopus 로고
    • MnSOD deficiency has a differential effect on disease progression in two different ALS mutant mouse models
    • F.L. Muller, Y. Liu, A. Jernigan, D. Borchelt, A. Richardson, and H. Van Remmen MnSOD deficiency has a differential effect on disease progression in two different ALS mutant mouse models Muscle Nerve 38 2008 1173 1183
    • (2008) Muscle Nerve , vol.38 , pp. 1173-1183
    • Muller, F.L.1    Liu, Y.2    Jernigan, A.3    Borchelt, D.4    Richardson, A.5    Van Remmen, H.6
  • 71
    • 0034801462 scopus 로고    scopus 로고
    • Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury
    • P.J. Crack, J.M. Taylor, N.J. Flentjar, J. De Haan, P. Hertzog, R.C. Iannello, and I. Kola Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury J. Neurochem. 78 2001 1389 1399
    • (2001) J. Neurochem. , vol.78 , pp. 1389-1399
    • Crack, P.J.1    Taylor, J.M.2    Flentjar, N.J.3    De Haan, J.4    Hertzog, P.5    Iannello, R.C.6    Kola, I.7
  • 73
    • 84885452439 scopus 로고    scopus 로고
    • Surprising behavioral and neurochemical enhancements in mice with combined mutations linked to Parkinsons disease
    • M.R. Hennis, M.A. Marvin, C.M. Taylor II, and M.S. Goldberg Surprising behavioral and neurochemical enhancements in mice with combined mutations linked to Parkinsons disease Neurobiol. Dis. 62 2014 113 123
    • (2014) Neurobiol. Dis. , vol.62 , pp. 113-123
    • Hennis, M.R.1    Marvin, M.A.2    Taylor, I.I.C.M.3    Goldberg, M.S.4
  • 76
    • 78649444069 scopus 로고    scopus 로고
    • Deficiency of methionine sulfoxide reductase A causes cellular dysfunction and mitochondrial damage in cardiac myocytes under physical and oxidative stresses
    • C. Nan, Y. Li, P.-Y. Jean-Charles, G. Chen, A. Kreymerman, H. Prentice, H. Weissbach, and X. Huang Deficiency of methionine sulfoxide reductase A causes cellular dysfunction and mitochondrial damage in cardiac myocytes under physical and oxidative stresses Biochem. Biophys. Res. Commun. 402 2010 608 613
    • (2010) Biochem. Biophys. Res. Commun. , vol.402 , pp. 608-613
    • Nan, C.1    Li, Y.2    Jean-Charles, P.-Y.3    Chen, G.4    Kreymerman, A.5    Prentice, H.6    Weissbach, H.7    Huang, X.8
  • 78
    • 34250880256 scopus 로고    scopus 로고
    • Elevated levels of brain-pathologies associated with neurodegenerative diseases in the methionine sulfoxide reductase A knockout mouse
    • R. Pal, D. Oien, F. Ersen, and J. Moskovitz Elevated levels of brain-pathologies associated with neurodegenerative diseases in the methionine sulfoxide reductase A knockout mouse Exp. Brain Res. 180 2007 765 774
    • (2007) Exp. Brain Res. , vol.180 , pp. 765-774
    • Pal, R.1    Oien, D.2    Ersen, F.3    Moskovitz, J.4
  • 79
    • 9344240424 scopus 로고    scopus 로고
    • Retardation of atherosclerosis by overexpression of catalase or both Cu/Zn-superoxide dismutase and catalase in mice lacking apolipoprotein e
    • H. Yang, L.J. Roberts, M.J. Shi, L.C. Zhou, B.R. Ballard, A. Richardson, and Z.M. Guo Retardation of atherosclerosis by overexpression of catalase or both Cu/Zn-superoxide dismutase and catalase in mice lacking apolipoprotein E Circ. Res. 95 2004 1075 1081
    • (2004) Circ. Res. , vol.95 , pp. 1075-1081
    • Yang, H.1    Roberts, L.J.2    Shi, M.J.3    Zhou, L.C.4    Ballard, B.R.5    Richardson, A.6    Guo, Z.M.7
  • 80
    • 84881557020 scopus 로고    scopus 로고
    • Oxidative damage associated with obesity is prevented by overexpression of CuZn- or Mn-superoxide dismutase
    • Y. Liu, W. Qi, A. Richardson, H. Van Remmen, Y. Ikeno, and A.B. Salmon Oxidative damage associated with obesity is prevented by overexpression of CuZn- or Mn-superoxide dismutase Biochem. Biophys. Res. Commun. 438 2013 78 83
    • (2013) Biochem. Biophys. Res. Commun. , vol.438 , pp. 78-83
    • Liu, Y.1    Qi, W.2    Richardson, A.3    Van Remmen, H.4    Ikeno, Y.5    Salmon, A.B.6
  • 81
    • 57049106701 scopus 로고    scopus 로고
    • Differential MRI patterns of brain atrophy in double or single transgenic mice for APP and/or SOD
    • J. Borg, and E. Chereul Differential MRI patterns of brain atrophy in double or single transgenic mice for APP and/or SOD J. Neurosci. Res. 86 2008 3275 3284
    • (2008) J. Neurosci. Res. , vol.86 , pp. 3275-3284
    • Borg, J.1    Chereul, E.2
  • 82
    • 20444471551 scopus 로고    scopus 로고
    • Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat+maneb-induced Parkinson disease phenotype
    • M. Thiruchelvam, O. Prokopenko, D.A. Cory-Slechta, E.K. Richfield, B. Buckley, and O. Mirochnitchenko Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat+maneb-induced Parkinson disease phenotype J. Biol. Chem. 280 2005 22530 22539
    • (2005) J. Biol. Chem. , vol.280 , pp. 22530-22539
    • Thiruchelvam, M.1    Prokopenko, O.2    Cory-Slechta, D.A.3    Richfield, E.K.4    Buckley, B.5    Mirochnitchenko, O.6
  • 83
    • 33644766038 scopus 로고    scopus 로고
    • Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy
    • X. Shen, S. Zheng, N.S. Metreveli, and P.N. Epstein Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy Diabetes 55 2006 798 805
    • (2006) Diabetes , vol.55 , pp. 798-805
    • Shen, X.1    Zheng, S.2    Metreveli, N.S.3    Epstein, P.N.4
  • 84
    • 68849110235 scopus 로고    scopus 로고
    • Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimers disease
    • M. Dumont, E. Wille, C. Stack, N.Y. Calingasan, M.F. Beal, and M.T. Lin Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimers disease FASEB J 23 2009 2459 2466
    • (2009) FASEB J , vol.23 , pp. 2459-2466
    • Dumont, M.1    Wille, E.2    Stack, C.3    Calingasan, N.Y.4    Beal, M.F.5    Lin, M.T.6
  • 85
    • 69449096141 scopus 로고    scopus 로고
    • Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimers disease
    • C.A. Massaad, T.M. Washington, R.G. Pautler, and E. Klann Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimers disease Proc. Natl. Acad. Sci. USA 106 2009 13576 13581
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 13576-13581
    • Massaad, C.A.1    Washington, T.M.2    Pautler, R.G.3    Klann, E.4
  • 86
    • 54949154110 scopus 로고    scopus 로고
    • Mitochondria-specific transgenic overexpression of phospholipid hydroperoxide glutathione peroxidase (GPx4) attenuates ischemia/reperfusion- associated cardiac dysfunction
    • E.R. Dabkowski, C.L. Williamson, and J.M. Hollander Mitochondria-specific transgenic overexpression of phospholipid hydroperoxide glutathione peroxidase (GPx4) attenuates ischemia/reperfusion-associated cardiac dysfunction Free Radic. Biol. Med. 45 2008 855 865
    • (2008) Free Radic. Biol. Med. , vol.45 , pp. 855-865
    • Dabkowski, E.R.1    Williamson, C.L.2    Hollander, J.M.3
  • 87
    • 84880144523 scopus 로고    scopus 로고
    • Overexpression of glutathione peroxidase 4 prevents beta-cell dysfunction induced by prolonged elevation of lipids in vivo
    • K. Koulajian, A. Ivovic, K. Ye, T. Desai, A. Shah, I.G. Fantus, Q. Ran, and A. Giacca Overexpression of glutathione peroxidase 4 prevents beta-cell dysfunction induced by prolonged elevation of lipids in vivo Am. J. Physiol. Endocrinol. Metab. 305 2013 E254 262
    • (2013) Am. J. Physiol. Endocrinol. Metab. , vol.305 , pp. 254-262
    • Koulajian, K.1    Ivovic, A.2    Ye, K.3    Desai, T.4    Shah, A.5    Fantus, I.G.6    Ran, Q.7    Giacca, A.8
  • 88
    • 84905864890 scopus 로고    scopus 로고
    • Reduction of glucose intolerance with high fat feeding is associated with anti-inflammatory effects of thioredoxin 1 overexpression in mice
    • A.B. Salmon, L.C. Flores, Y. Li, H. Van Remmen, A. Richardson, and Y. Ikeno Reduction of glucose intolerance with high fat feeding is associated with anti-inflammatory effects of thioredoxin 1 overexpression in mice Pathobiol. Aging Age Relat. Dis 2012 2
    • (2012) Pathobiol. Aging Age Relat. Dis , pp. 2
    • Salmon, A.B.1    Flores, L.C.2    Li, Y.3    Van Remmen, H.4    Richardson, A.5    Ikeno, Y.6
  • 89
    • 0037056109 scopus 로고    scopus 로고
    • Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity
    • K. Shioji, C. Kishimoto, H. Nakamura, H. Masutani, Z. Yuan, S.-i. Oka, and J. Yodoi Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity Circulation 106 2002 1403 1409
    • (2002) Circulation , vol.106 , pp. 1403-1409
    • Shioji, K.1    Kishimoto, C.2    Nakamura, H.3    Masutani, H.4    Yuan, Z.5    Oka, S.-I.6    Yodoi, J.7
  • 90
    • 0038279860 scopus 로고    scopus 로고
    • Thioredoxin redox signaling in the ischemic heart: An insight with transgenic mice overexpressing Trx1
    • T. Turoczi, V.W.-H. Chang, R.M. Engelman, N. Maulik, Y.-S. Ho, and D.K. Das Thioredoxin redox signaling in the ischemic heart: an insight with transgenic mice overexpressing Trx1 J. Mol. Cell. Cardiol. 35 2003 695 704
    • (2003) J. Mol. Cell. Cardiol. , vol.35 , pp. 695-704
    • Turoczi, T.1    Chang, V.W.-H.2    Engelman, R.M.3    Maulik, N.4    Ho, Y.-S.5    Das, D.K.6
  • 97
    • 78650681173 scopus 로고    scopus 로고
    • SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse
    • L.R. Fischer, A. Igoudjil, J. Magrané, Y. Li, J.M. Hansen, G. Manfredi, and J.D. Glass SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse Brain 134 2011 196 209
    • (2011) Brain , vol.134 , pp. 196-209
    • Fischer, L.R.1    Igoudjil, A.2    Magrané, J.3    Li, Y.4    Hansen, J.M.5    Manfredi, G.6    Glass, J.D.7
  • 102
    • 84862325005 scopus 로고    scopus 로고
    • Mitochondria-targeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimers disease: Implications for neuroprotection and lifespan extension
    • P. Mao, M. Manczak, M.J. Calkins, Q. Truong, T.P. Reddy, A.P. Reddy, U. Shirendeb, H.-H. Lo, P.S. Rabinovitch, and P.H. Reddy Mitochondria-targeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimers disease: implications for neuroprotection and lifespan extension Hum. Mol. Genet 21 2012 2973 2990
    • (2012) Hum. Mol. Genet , vol.21 , pp. 2973-2990
    • Mao, P.1    Manczak, M.2    Calkins, M.J.3    Truong, Q.4    Reddy, T.P.5    Reddy, A.P.6    Shirendeb, U.7    Lo, H.-H.8    Rabinovitch, P.S.9    Reddy, P.H.10
  • 103
    • 84876099875 scopus 로고    scopus 로고
    • Enhanced hippocampusdependent memory and reduced anxiety in mice overexpressing human catalase in mitochondria
    • H.J. O. Reid, A.J. Lance, G.Z. Damian, L.L. Charles, and R. Jacob Enhanced hippocampusdependent memory and reduced anxiety in mice overexpressing human catalase in mitochondria J. Neurochem. 125 2013 303 313
    • (2013) J. Neurochem. , vol.125 , pp. 303-313
    • Reid, H.J.O.1    Lance, A.J.2    Damian, G.Z.3    Charles, L.L.4    Jacob, R.5
  • 105
    • 29244485582 scopus 로고    scopus 로고
    • Organ-specific increase in mutation accumulation and apoptosis rate in CuZn-superoxide dismutase-deficient mice
    • R.A. Busuttil, A.M. Garcia, C. Cabrera, A. Rodriguez, Y. Suh, W.H. Kim, T.-T. Huang, and J. Vijg Organ-specific increase in mutation accumulation and apoptosis rate in CuZn-superoxide dismutase-deficient mice Cancer Res. 65 2005 11271 11275
    • (2005) Cancer Res. , vol.65 , pp. 11271-11275
    • Busuttil, R.A.1    Garcia, A.M.2    Cabrera, C.3    Rodriguez, A.4    Suh, Y.5    Kim, W.H.6    Huang, T.-T.7    Vijg, J.8
  • 110
    • 34249815785 scopus 로고    scopus 로고
    • Deficiency of manganese superoxide dismutase in hepatocytes disrupts zonated gene expression in mouse liver
    • J. Lenart, F. Dombrowski, A. Görlach, and T. Kietzmann Deficiency of manganese superoxide dismutase in hepatocytes disrupts zonated gene expression in mouse liver Arch. Biochem. Biophys. 462 2007 238 244
    • (2007) Arch. Biochem. Biophys. , vol.462 , pp. 238-244
    • Lenart, J.1    Dombrowski, F.2    Görlach, A.3    Kietzmann, T.4
  • 114
    • 33745154155 scopus 로고    scopus 로고
    • Conditional knockout of Mn superoxide dismutase in postnatal motor neurons reveals resistance to mitochondrial generated superoxide radicals
    • H. Misawa, K. Nakata, J. Matsuura, Y. Moriwaki, K. Kawashima, T. Shimizu, T. Shirasawa, and R. Takahashi Conditional knockout of Mn superoxide dismutase in postnatal motor neurons reveals resistance to mitochondrial generated superoxide radicals Neurobiol. Dis. 23 2006 169 177
    • (2006) Neurobiol. Dis. , vol.23 , pp. 169-177
    • Misawa, H.1    Nakata, K.2    Matsuura, J.3    Moriwaki, Y.4    Kawashima, K.5    Shimizu, T.6    Shirasawa, T.7    Takahashi, R.8
  • 115
    • 84867509100 scopus 로고    scopus 로고
    • Manganese superoxide dismutase is dispensable for post-natal development and lactation in the murine mammary gland
    • A.J. Case, and F.E. Domann Manganese superoxide dismutase is dispensable for post-natal development and lactation in the murine mammary gland Free Radic. Res. 46 2012 1361 1368
    • (2012) Free Radic. Res. , vol.46 , pp. 1361-1368
    • Case, A.J.1    Domann, F.E.2
  • 117
    • 84861663194 scopus 로고    scopus 로고
    • Neurodegeneration and early lethality in superoxide dismutase 2-deficient mice: A comprehensive analysis of the central and peripheral nervous systems
    • S.S. Oh, K.A. Sullivan, J.E. Wilkinson, C. Backus, J.M. Hayes, S.A. Sakowski, and E.L. Feldman Neurodegeneration and early lethality in superoxide dismutase 2-deficient mice: a comprehensive analysis of the central and peripheral nervous systems Neuroscience 212 2012 201 213
    • (2012) Neuroscience , vol.212 , pp. 201-213
    • Oh, S.S.1    Sullivan, K.A.2    Wilkinson, J.E.3    Backus, C.4    Hayes, J.M.5    Sakowski, S.A.6    Feldman, E.L.7
  • 122
    • 34547097247 scopus 로고    scopus 로고
    • Brain IRS2 signaling coordinates life span and nutrient homeostasis
    • A. Taguchi, L.M. Wartschow, and M.F. White Brain IRS2 signaling coordinates life span and nutrient homeostasis Science 317 2007 369 372
    • (2007) Science , vol.317 , pp. 369-372
    • Taguchi, A.1    Wartschow, L.M.2    White, M.F.3
  • 123
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • M. Blüher, B.B. Kahn, and C.R. Kahn Extended longevity in mice lacking the insulin receptor in adipose tissue Science 299 2003 572 574
    • (2003) Science , vol.299 , pp. 572-574
    • Blüher, M.1    Kahn, B.B.2    Kahn, C.R.3
  • 124
    • 84891777733 scopus 로고    scopus 로고
    • Glutathionylated lipid aldehydes are products of adipocyte oxidative stress and activators of macrophage inflammation
    • B.I. Frohnert, E.K. Long, W.S. Hahn, and D.A. Bernlohr Glutathionylated lipid aldehydes are products of adipocyte oxidative stress and activators of macrophage inflammation Diabetes 63 2014 89 100
    • (2014) Diabetes , vol.63 , pp. 89-100
    • Frohnert, B.I.1    Long, E.K.2    Hahn, W.S.3    Bernlohr, D.A.4
  • 125
    • 34247361278 scopus 로고    scopus 로고
    • Carbonylation of adipose proteins in obesity and insulin resistance: Identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal
    • P.A. Grimsrud, M.J. Picklo, T.J. Griffin, and D.A. Bernlohr Carbonylation of adipose proteins in obesity and insulin resistance: identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal Mol. Cell. Proteomics 6 2007 624 637
    • (2007) Mol. Cell. Proteomics , vol.6 , pp. 624-637
    • Grimsrud, P.A.1    Picklo, M.J.2    Griffin, T.J.3    Bernlohr, D.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.