Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1

Nature

Volumn 434, Issue 7029, 2005, Pages 113-118

  Rodgers, Joseph T ^a   Lerin, Carlos ^a   Haas, Wilhelm ^b   Gygi, Steven P ^b   Spiegelman, Bruce M ^b   Puigserver, Pere ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; BLOOD; GENES; HORMONES; METABOLISM; MOLECULAR DYNAMICS;

GLYCONEOGENIC GENES; LYSINE; MOLECULAR MECHANISM; NUTRIENTS;

GLUCOSE;

CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUCOKINASE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; HISTONE DEACETYLASE; LYSINE; MESSENGER RNA; PROTEIN SIRT1; PYRUVATE KINASE; PYRUVIC ACID; SILENT INFORMATION REGULATOR PROTEIN 2; SIRTUIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PGC 1ALPHA; UNCLASSIFIED DRUG; CYCLIC AMP; INSULIN; LACTIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE; PPARGC1A PROTEIN, MOUSE; SIRT1 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

BIOLOGY;

ACETYLATION; ADENOVIRUS; AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; DEACETYLATION; DIABETES MELLITUS; DIET RESTRICTION; ENERGY METABOLISM; GENE REPRESSION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLYCOLYSIS; HUMAN; HUMAN CELL; LIFESPAN; LIVER METABOLISM; MOUSE; NONHUMAN; NUTRIENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; TRANSCRIPTION REGULATION; ANIMAL; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HOMEOSTASIS; LIVER; LIVER CELL; LONGEVITY; METABOLISM; NUTRITIONAL STATUS; PROTEIN BINDING;

ADENOVIRIDAE; ANIMALIA; MAMMALIA;

ACETYLATION; ANIMALS; CALORIC RESTRICTION; CYCLIC AMP; FASTING; GENE EXPRESSION REGULATION; GLUCONEOGENESIS; GLUCOSE; GLYCOLYSIS; HEPATOCYTES; HOMEOSTASIS; INSULIN; LACTIC ACID; LIVER; LONGEVITY; LYSINE; MICE; NAD; NUTRITIONAL STATUS; PROTEIN BINDING; PYRUVIC ACID; RATS; RNA, MESSENGER; SIRTUINS; TRANS-ACTIVATORS;

EID: 14544282413     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03354     Document Type: Article

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