Dual phosphorylation of Sin1 at T86 and T398 negatively regulates mTORC2 complex integrity and activity

Protein and Cell

Volumn 5, Issue 3, 2014, Pages 171-177

  Liu, Pengda ^a   Guo, Jianping ^a   Gan, Wenjian ^a   Wei, Wenyi ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR RECEPTOR BOUND PROTEIN 10; INSULIN RECEPTOR SUBSTRATE 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN C RECEPTOR;

APOPTOSIS; ARTICLE; CELL METABOLISM; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; ENZYME REPRESSION; GENE MUTATION; HUMAN; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SUBUNIT; SIGNAL PROCESSING; SIGNAL TRANSDUCTION; TUMOR PROMOTION;

MAMMALIA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; HUMANS; MODELS, BIOLOGICAL; MULTIPROTEIN COMPLEXES; PHOSPHORYLATION; PHOSPHOTHREONINE; TOR SERINE-THREONINE KINASES;

EID: 84898596335     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-014-0021-8     Document Type: Article

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