Assessment of mitochondrial biogenesis and mtorc1 signaling during chronic rapamycin feeding in male and female mice

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 68, Issue 12 A, 2013, Pages 1493-1501

  Drake, Joshua C ^a   Peelor III, Frederick F ^a   Biela, Laurie M ^a   Watkins, Molly K ^a   Miller, Richard A ^b   Hamilton, Karyn L ^a   Miller, Benjamin F ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

2H2O; Deuterium; Mitochondria; mTOR; Protein synthesis; Rapamycin

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; DEUTERIUM OXIDE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; PROTEIN S6; RAPAMYCIN; RIBOSOMAL PROTEIN S6, MOUSE; TARGET OF RAPAMYCIN KINASE; DEUTERIUM;

ANIMAL; DIET; DRUG EFFECTS; FEMALE; GENETICS; LONGEVITY; MALE; METABOLISM; MITOCHONDRIAL DYNAMICS; MITOCHONDRION; MOUSE; PHOSPHORYLATION; PROCEDURES; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; 2H2O; ARTICLE; DRUG EFFECT; METHODOLOGY; MTOR.;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; DEUTERIUM OXIDE; DIET; FEMALE; LONGEVITY; MALE; MICE; MITOCHONDRIA; MITOCHONDRIAL TURNOVER; MULTIPROTEIN COMPLEXES; MUSCLE, SKELETAL; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RIBOSOMAL PROTEIN S6; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES;

2H2O; DEUTERIUM; MITOCHONDRIA; MTOR.; PROTEIN SYNTHESIS; RAPAMYCIN;

EID: 84891620324     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glt047     Document Type: Article

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