-
1
-
-
0141677687
-
Longevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatin
-
Bitterman K.J., Medvedik O., and Sinclair D.A. Longevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatin. Microbiol. Mol. Biol. Rev. 67 (2003) 376-399
-
(2003)
Microbiol. Mol. Biol. Rev.
, vol.67
, pp. 376-399
-
-
Bitterman, K.J.1
Medvedik, O.2
Sinclair, D.A.3
-
2
-
-
17144429302
-
Calorie restriction, SIRT1 and metabolism: understanding longevity
-
Bordone L., and Guarente L. Calorie restriction, SIRT1 and metabolism: understanding longevity. Nat. Rev. Mol. Cell Biol. 6 (2005) 298-305
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 298-305
-
-
Bordone, L.1
Guarente, L.2
-
3
-
-
5444269465
-
Hypophosphorylated SR splicing factors transiently localize around active nucleolar organizing regions in telophase daughter nuclei
-
Bubulya P.A., Prasanth K.V., Deerinck T.J., Gerlich D., Beaudouin J., Ellisman M.H., Ellenberg J., and Spector D.L. Hypophosphorylated SR splicing factors transiently localize around active nucleolar organizing regions in telophase daughter nuclei. J. Cell Biol. 167 (2004) 51-63
-
(2004)
J. Cell Biol.
, vol.167
, pp. 51-63
-
-
Bubulya, P.A.1
Prasanth, K.V.2
Deerinck, T.J.3
Gerlich, D.4
Beaudouin, J.5
Ellisman, M.H.6
Ellenberg, J.7
Spector, D.L.8
-
4
-
-
9444232851
-
Boundary elements and nuclear organization
-
Capelson M., and Corces V.G. Boundary elements and nuclear organization. Biol. Cell. 96 (2004) 617-629
-
(2004)
Biol. Cell.
, vol.96
, pp. 617-629
-
-
Capelson, M.1
Corces, V.G.2
-
5
-
-
2442485925
-
Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140
-
Christian M., Tullet J.M., and Parker M.G. Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140. J. Biol. Chem. 279 (2004) 15645-15651
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 15645-15651
-
-
Christian, M.1
Tullet, J.M.2
Parker, M.G.3
-
6
-
-
0021100690
-
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
-
Dignam J.D., Lebovitz R.M., and Roeder R.G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11 (1983) 1475-1489
-
(1983)
Nucleic Acids Res.
, vol.11
, pp. 1475-1489
-
-
Dignam, J.D.1
Lebovitz, R.M.2
Roeder, R.G.3
-
7
-
-
0034641739
-
Identification of a nuclear domain with deacetylase activity
-
Downes M., Ordentlich P., Kao H.Y., Alvarez J.G., and Evans R.M. Identification of a nuclear domain with deacetylase activity. Proc. Natl. Acad. Sci. USA 97 (2000) 10330-10335
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10330-10335
-
-
Downes, M.1
Ordentlich, P.2
Kao, H.Y.3
Alvarez, J.G.4
Evans, R.M.5
-
8
-
-
0842324779
-
Obesity wars: molecular progress confronts an expanding epidemic
-
Flier J.S. Obesity wars: molecular progress confronts an expanding epidemic. Cell 116 (2004) 337-350
-
(2004)
Cell
, vol.116
, pp. 337-350
-
-
Flier, J.S.1
-
9
-
-
23944476164
-
Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha
-
Handschin C., Lin J., Rhee J., Peyer A.K., Chin S., Wu P.H., Meyer U.A., and Spiegelman B.M. Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha. Cell 122 (2005) 505-515
-
(2005)
Cell
, vol.122
, pp. 505-515
-
-
Handschin, C.1
Lin, J.2
Rhee, J.3
Peyer, A.K.4
Chin, S.5
Wu, P.H.6
Meyer, U.A.7
Spiegelman, B.M.8
-
10
-
-
0036847620
-
Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes
-
Hassan A.H., Prochasson P., Neely K.E., Galasinski S.C., Chandy M., Carrozza M.J., and Workman J.L. Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes. Cell 111 (2002) 369-379
-
(2002)
Cell
, vol.111
, pp. 369-379
-
-
Hassan, A.H.1
Prochasson, P.2
Neely, K.E.3
Galasinski, S.C.4
Chandy, M.5
Carrozza, M.J.6
Workman, J.L.7
-
11
-
-
0035855905
-
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
-
Herzig S., Long F., Jhala U.S., Hedrick S., Quinn R., Bauer A., Rudolph D., Schutz G., Yoon C., Puigserver P., et al. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature 413 (2001) 179-183
-
(2001)
Nature
, vol.413
, pp. 179-183
-
-
Herzig, S.1
Long, F.2
Jhala, U.S.3
Hedrick, S.4
Quinn, R.5
Bauer, A.6
Rudolph, D.7
Schutz, G.8
Yoon, C.9
Puigserver, P.10
-
12
-
-
0032231606
-
Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies
-
Hodges M., Tissot C., Howe K., Grimwade D., and Freemont P.S. Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies. Am. J. Hum. Genet. 63 (1998) 297-304
-
(1998)
Am. J. Hum. Genet.
, vol.63
, pp. 297-304
-
-
Hodges, M.1
Tissot, C.2
Howe, K.3
Grimwade, D.4
Freemont, P.S.5
-
13
-
-
0242569349
-
A proteomic approach for quantitation of phosphorylation using stable isotope labeling in cell culture
-
Ibarrola N., Kalume D.E., Gronborg M., Iwahori A., and Pandey A. A proteomic approach for quantitation of phosphorylation using stable isotope labeling in cell culture. Anal. Chem. 75 (2003) 6043-6049
-
(2003)
Anal. Chem.
, vol.75
, pp. 6043-6049
-
-
Ibarrola, N.1
Kalume, D.E.2
Gronborg, M.3
Iwahori, A.4
Pandey, A.5
-
14
-
-
0034682736
-
Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis
-
Ikura T., Ogryzko V.V., Grigoriev M., Groisman R., Wang J., Horikoshi M., Scully R., Qin J., and Nakatani Y. Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell 102 (2000) 463-473
-
(2000)
Cell
, vol.102
, pp. 463-473
-
-
Ikura, T.1
Ogryzko, V.V.2
Grigoriev, M.3
Groisman, R.4
Wang, J.5
Horikoshi, M.6
Scully, R.7
Qin, J.8
Nakatani, Y.9
-
15
-
-
0025167967
-
Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene
-
Imai E., Stromstedt P.E., Quinn P.G., Carlstedt-Duke J., Gustafsson J.A., and Granner D.K. Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene. Mol. Cell. Biol. 10 (1990) 4712-4719
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 4712-4719
-
-
Imai, E.1
Stromstedt, P.E.2
Quinn, P.G.3
Carlstedt-Duke, J.4
Gustafsson, J.A.5
Granner, D.K.6
-
16
-
-
0037418829
-
The polycomb protein Pc2 is a SUMO E3
-
Kagey M.H., Melhuish T.A., and Wotton D. The polycomb protein Pc2 is a SUMO E3. Cell 113 (2003) 127-137
-
(2003)
Cell
, vol.113
, pp. 127-137
-
-
Kagey, M.H.1
Melhuish, T.A.2
Wotton, D.3
-
18
-
-
27144506185
-
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
-
Koo S.H., Flechner L., Qi L., Zhang X., Screaton R.A., Jeffries S., Hedrick S., Xu W., Boussouar F., Brindle P., et al. The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature 437 (2005) 1109-1111
-
(2005)
Nature
, vol.437
, pp. 1109-1111
-
-
Koo, S.H.1
Flechner, L.2
Qi, L.3
Zhang, X.4
Screaton, R.A.5
Jeffries, S.6
Hedrick, S.7
Xu, W.8
Boussouar, F.9
Brindle, P.10
-
19
-
-
2442701392
-
PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3
-
Koo S.H., Satoh H., Herzig S., Lee C.H., Hedrick S., Kulkarni R., Evans R.M., Olefsky J., and Montminy M. PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nat. Med. 10 (2004) 530-534
-
(2004)
Nat. Med.
, vol.10
, pp. 530-534
-
-
Koo, S.H.1
Satoh, H.2
Herzig, S.3
Lee, C.H.4
Hedrick, S.5
Kulkarni, R.6
Evans, R.M.7
Olefsky, J.8
Montminy, M.9
-
20
-
-
10844233155
-
Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions
-
Kusch T., Florens L., Macdonald W.H., Swanson S.K., Glaser R.L., Yates III J.R., Abmayr S.M., Washburn M.P., and Workman J.L. Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions. Science 306 (2004) 2084-2087
-
(2004)
Science
, vol.306
, pp. 2084-2087
-
-
Kusch, T.1
Florens, L.2
Macdonald, W.H.3
Swanson, S.K.4
Glaser, R.L.5
Yates III, J.R.6
Abmayr, S.M.7
Washburn, M.P.8
Workman, J.L.9
-
21
-
-
0041669439
-
Nuclear speckles: a model for nuclear organelles
-
Lamond A.I., and Spector D.L. Nuclear speckles: a model for nuclear organelles. Nat. Rev. Mol. Cell Biol. 4 (2003) 605-612
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 605-612
-
-
Lamond, A.I.1
Spector, D.L.2
-
22
-
-
2942532305
-
Nuclear receptor corepressor RIP140 regulates fat accumulation
-
Leonardsson G., Steel J.H., Christian M., Pocock V., Milligan S., Bell J., So P.W., Medina-Gomez G., Vidal-Puig A., White R., and Parker M.G. Nuclear receptor corepressor RIP140 regulates fat accumulation. Proc. Natl. Acad. Sci. USA 101 (2004) 8437-8442
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8437-8442
-
-
Leonardsson, G.1
Steel, J.H.2
Christian, M.3
Pocock, V.4
Milligan, S.5
Bell, J.6
So, P.W.7
Medina-Gomez, G.8
Vidal-Puig, A.9
White, R.10
Parker, M.G.11
-
23
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
Lin J., Handschin C., and Spiegelman B.M. Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab. 1 (2005) 361-370
-
(2005)
Cell Metab.
, vol.1
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
24
-
-
0038820074
-
c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation
-
Liu X., Tesfai J., Evrard Y.A., Dent S.Y., and Martinez E. c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation. J. Biol. Chem. 278 (2003) 20405-20412
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 20405-20412
-
-
Liu, X.1
Tesfai, J.2
Evrard, Y.A.3
Dent, S.Y.4
Martinez, E.5
-
25
-
-
0034812915
-
Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo
-
Martinez E., Palhan V.B., Tjernberg A., Lymar E.S., Gamper A.M., Kundu T.K., Chait B.T., and Roeder R.G. Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. Mol. Cell. Biol. 21 (2001) 6782-6795
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6782-6795
-
-
Martinez, E.1
Palhan, V.B.2
Tjernberg, A.3
Lymar, E.S.4
Gamper, A.M.5
Kundu, T.K.6
Chait, B.T.7
Roeder, R.G.8
-
26
-
-
0033638283
-
Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1
-
Monsalve M., Wu Z., Adelmant G., Puigserver P., Fan M., and Spiegelman B.M. Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol. Cell 6 (2000) 307-316
-
(2000)
Mol. Cell
, vol.6
, pp. 307-316
-
-
Monsalve, M.1
Wu, Z.2
Adelmant, G.3
Puigserver, P.4
Fan, M.5
Spiegelman, B.M.6
-
27
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha V.K., Lindgren C.M., Eriksson K.F., Subramanian A., Sihag S., Lehar J., Puigserver P., Carlsson E., Ridderstrale M., Laurila E., et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat. Genet. 34 (2003) 267-273
-
(2003)
Nat. Genet.
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
Subramanian, A.4
Sihag, S.5
Lehar, J.6
Puigserver, P.7
Carlsson, E.8
Ridderstrale, M.9
Laurila, E.10
-
28
-
-
0035185021
-
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
-
Nakae J., Kitamura T., Silver D.L., and Accili D. The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. J. Clin. Invest. 108 (2001) 1359-1367
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1359-1367
-
-
Nakae, J.1
Kitamura, T.2
Silver, D.L.3
Accili, D.4
-
29
-
-
0347381286
-
Immunoaffinity purification of mammalian protein complexes
-
Nakatani Y., and Ogryzko V. Immunoaffinity purification of mammalian protein complexes. Methods Enzymol. 370 (2003) 430-444
-
(2003)
Methods Enzymol.
, vol.370
, pp. 430-444
-
-
Nakatani, Y.1
Ogryzko, V.2
-
30
-
-
0032589689
-
Activation of PPARgamma coactivator-1 through transcription factor docking
-
Puigserver P., Adelmant G., Wu Z., Fan M., Xu J., O'Malley B., and Spiegelman B.M. Activation of PPARgamma coactivator-1 through transcription factor docking. Science 286 (1999) 1368-1371
-
(1999)
Science
, vol.286
, pp. 1368-1371
-
-
Puigserver, P.1
Adelmant, G.2
Wu, Z.3
Fan, M.4
Xu, J.5
O'Malley, B.6
Spiegelman, B.M.7
-
31
-
-
0038187621
-
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
-
Puigserver P., Rhee J., Donovan J., Walkey C.J., Yoon J.C., Oriente F., Kitamura Y., Altomonte J., Dong H., Accili D., and Spiegelman B.M. Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature 423 (2003) 550-555
-
(2003)
Nature
, vol.423
, pp. 550-555
-
-
Puigserver, P.1
Rhee, J.2
Donovan, J.3
Walkey, C.J.4
Yoon, J.C.5
Oriente, F.6
Kitamura, Y.7
Altomonte, J.8
Dong, H.9
Accili, D.10
Spiegelman, B.M.11
-
32
-
-
0242349197
-
Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis
-
Rhee J., Inoue Y., Yoon J.C., Puigserver P., Fan M., Gonzalez F.J., and Spiegelman B.M. Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. Proc. Natl. Acad. Sci. USA 100 (2003) 4012-4017
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4012-4017
-
-
Rhee, J.1
Inoue, Y.2
Yoon, J.C.3
Puigserver, P.4
Fan, M.5
Gonzalez, F.J.6
Spiegelman, B.M.7
-
33
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers J.T., Lerin C., Haas W., Gygi S.P., Spiegelman B.M., and Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434 (2005) 113-118
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
34
-
-
8644224064
-
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
-
Rogina B., and Helfand S.L. Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc. Natl. Acad. Sci. USA 101 (2004) 15998-16003
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15998-16003
-
-
Rogina, B.1
Helfand, S.L.2
-
35
-
-
0035936763
-
New perspectives into the molecular pathogenesis and treatment of type 2 diabetes
-
Saltiel A.R. New perspectives into the molecular pathogenesis and treatment of type 2 diabetes. Cell 104 (2001) 517-529
-
(2001)
Cell
, vol.104
, pp. 517-529
-
-
Saltiel, A.R.1
-
36
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman G.I. Cellular mechanisms of insulin resistance. J. Clin. Invest. 106 (2000) 171-176
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
37
-
-
0038036024
-
Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells
-
St-Pierre J., Lin J., Krauss S., Tarr P.T., Yang R., Newgard C.B., and Spiegelman B.M. Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells. J. Biol. Chem. 278 (2003) 26597-26603
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26597-26603
-
-
St-Pierre, J.1
Lin, J.2
Krauss, S.3
Tarr, P.T.4
Yang, R.5
Newgard, C.B.6
Spiegelman, B.M.7
-
38
-
-
0344413490
-
Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha
-
Wallberg A.E., Yamamura S., Malik S., Spiegelman B.M., and Roeder R.G. Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha. Mol. Cell 12 (2003) 1137-1149
-
(2003)
Mol. Cell
, vol.12
, pp. 1137-1149
-
-
Wallberg, A.E.1
Yamamura, S.2
Malik, S.3
Spiegelman, B.M.4
Roeder, R.G.5
-
39
-
-
0014082605
-
The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver
-
Williamson D.H., Lund P., and Krebs H.A. The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver. Biochem. J. 103 (1967) 514-527
-
(1967)
Biochem. J.
, vol.103
, pp. 514-527
-
-
Williamson, D.H.1
Lund, P.2
Krebs, H.A.3
-
40
-
-
0035855858
-
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
-
Yoon J.C., Puigserver P., Chen G., Donovan J., Wu Z., Rhee J., Adelmant G., Stafford J., Kahn C.R., Granner D.K., et al. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 413 (2001) 131-138
-
(2001)
Nature
, vol.413
, pp. 131-138
-
-
Yoon, J.C.1
Puigserver, P.2
Chen, G.3
Donovan, J.4
Wu, Z.5
Rhee, J.6
Adelmant, G.7
Stafford, J.8
Kahn, C.R.9
Granner, D.K.10
-
41
-
-
0035064047
-
Regulation of glucocorticoid receptor activity by 14-3-3-dependent intracellular relocalization of the corepressor RIP140
-
Zilliacus J., Holter E., Wakui H., Tazawa H., Treuter E., and Gustafsson J.A. Regulation of glucocorticoid receptor activity by 14-3-3-dependent intracellular relocalization of the corepressor RIP140. Mol. Endocrinol. 15 (2001) 501-511
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 501-511
-
-
Zilliacus, J.1
Holter, E.2
Wakui, H.3
Tazawa, H.4
Treuter, E.5
Gustafsson, J.A.6
|