-
1
-
-
0036753494
-
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control
-
Loewith, R. et al. Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol. Cell 10, 457-468 (2002).
-
(2002)
Mol. Cell
, vol.10
, pp. 457-468
-
-
Loewith, R.1
-
2
-
-
0037345059
-
Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae
-
Wedaman, K. P. et al. Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae. Mol. Biol. Cell 14, 1204-1220 (2003).
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 1204-1220
-
-
Wedaman, K.P.1
-
4
-
-
0037178781
-
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
-
Hara, K. et al. Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action. Cell 110, 177-189 (2002).
-
(2002)
Cell
, vol.110
, pp. 177-189
-
-
Hara, K.1
-
5
-
-
0037178786
-
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
Kim, D. H. et al. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110, 163-175 (2002).
-
(2002)
Cell
, vol.110
, pp. 163-175
-
-
Kim, D.H.1
-
6
-
-
0037623417
-
GβL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR
-
Kim, D. H. et al. GβL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol. Cell 11, 895-904 (2003).
-
(2003)
Mol. Cell
, vol.11
, pp. 895-904
-
-
Kim, D.H.1
-
8
-
-
0042823530
-
mTOR signaling to translation
-
Gingras, A. C., Raught, B. & Sonenberg, N. mTOR signaling to translation. Curr. Top. Microbiol. Immunol. 279, 169-197 (2004).
-
(2004)
Curr. Top Microbiol. Immunol.
, vol.279
, pp. 169-197
-
-
Gingras, A.C.1
Raught, B.2
Sonenberg, N.3
-
9
-
-
0029831167
-
Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002
-
Brunn, G. J. et al. Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. EMBO J. 15, 5256-5267 (1996).
-
(1996)
EMBO J.
, vol.15
, pp. 5256-5267
-
-
Brunn, G.J.1
-
10
-
-
0033199892
-
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine
-
Sarkaria, J. N. et al. Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res. 59, 4375-4382 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 4375-4382
-
-
Sarkaria, J.N.1
-
11
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies, S. P., Reddy, H., Caivano, M. & Cohen, P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351, 95-105 (2000).
-
(2000)
Biochem. J.
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
12
-
-
0029123888
-
Growth factor-induced actin reorganization in Swiss 3T3 cells
-
Ridley, A. J. Growth factor-induced actin reorganization in Swiss 3T3 cells. Methods Enzymol. 256, 306-313 (1995).
-
(1995)
Methods Enzymol.
, vol.256
, pp. 306-313
-
-
Ridley, A.J.1
-
13
-
-
0035475321
-
Paxillin: A focal adhesion-associated adaptor protein
-
Schaller, M. D. Paxillin: a focal adhesion-associated adaptor protein. Oncogene 20, 6459-6472 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 6459-6472
-
-
Schaller, M.D.1
-
14
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville, S. & Hall, A. Rho GTPases in cell biology, Nature 420, 629-635 (2002).
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
15
-
-
2342545519
-
Target of rapamycin (TOR): An integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
-
Fingar, D. C. & Blenis, J. Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene 23, 3151-3171 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 3151-3171
-
-
Fingar, D.C.1
Blenis, J.2
-
16
-
-
0038645859
-
Mammalian target of rapamycin and protein kinase A signaling mediate the cardiac transcriptional response to glutamine
-
Xia, Y. et al. Mammalian target of rapamycin and protein kinase A signaling mediate the cardiac transcriptional response to glutamine. J. Biol. Chem. 278, 13143-13150 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13143-13150
-
-
Xia, Y.1
-
17
-
-
0033775869
-
The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho
-
Lamb, R. F. et al. The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho. Nature Cell Biol. 2, 281-287 (2000).
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 281-287
-
-
Lamb, R.F.1
-
18
-
-
0037028305
-
Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration
-
Astrinidis, A. et al. Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration. Oncogene 21, 8470-8476 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 8470-8476
-
-
Astrinidis, A.1
-
19
-
-
0030906569
-
The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2
-
Schmidt, A., Bickle, M., Beck, T. & Hall, M. N. The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2. Cell 88, 531-542 (1997).
-
(1997)
Cell
, vol.88
, pp. 531-542
-
-
Schmidt, A.1
Bickle, M.2
Beck, T.3
Hall, M.N.4
-
20
-
-
0029890229
-
The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1
-
Chou, M. M. & Blenis, J. The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1. Cell 85, 573-583 (1996).
-
(1996)
Cell
, vol.85
, pp. 573-583
-
-
Chou, M.M.1
Blenis, J.2
-
21
-
-
0344663973
-
PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1
-
Fang, Y. et al. PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1. Curr. Biol. 13, 2037-2044 (2003).
-
(2003)
Curr. Biol.
, vol.13
, pp. 2037-2044
-
-
Fang, Y.1
-
22
-
-
0034629365
-
FKBP12-rapamycin-associated protein (FRAP) autophosphorylates at serine 2481 under translationally repressive conditions
-
Peterson, R. T., Beal, P. A., Comb, M. J. & Schreiber, S. L. FKBP12-rapamycin-associated protein (FRAP) autophosphorylates at serine 2481 under translationally repressive conditions. J. Biol. Chem. 275, 7416-7423 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 7416-7423
-
-
Peterson, R.T.1
Beal, P.A.2
Comb, M.J.3
Schreiber, S.L.4
-
23
-
-
1942487890
-
Dissociation of raptor from mTOR is a mechanism of rapamycin-induced inhibition of mTOR function
-
Oshiro, N. et al. Dissociation of raptor from mTOR is a mechanism of rapamycin-induced inhibition of mTOR function. Genes Cells 9, 359-366 (2004).
-
(2004)
Genes Cells
, vol.9
, pp. 359-366
-
-
Oshiro, N.1
-
24
-
-
3342895823
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
-
Dos, D. S. et al. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr. Biol. 14, 1296-1302 (2004).
-
(2004)
Curr. Biol.
, vol.14
, pp. 1296-1302
-
-
Dos, D.S.1
-
25
-
-
0030007037
-
Mammalian CAP interacts with CAP, CAP2, and actin
-
Hubberstey, A., Yu, G., Loewith, R., Lakusta, C. & Young, D. Mammalian CAP interacts with CAP, CAP2, and actin. J. Cell. Biochem. 61, 459-466 (1996).
-
(1996)
J. Cell. Biochem.
, vol.61
, pp. 459-466
-
-
Hubberstey, A.1
Yu, G.2
Loewith, R.3
Lakusta, C.4
Young, D.5
-
26
-
-
0026654125
-
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
-
Ridley, A. J., Paterson, H. F., Johnston, C. L., Diekmann, D. & Hall, A. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70, 401-410 (1992).
-
(1992)
Cell
, vol.70
, pp. 401-410
-
-
Ridley, A.J.1
Paterson, H.F.2
Johnston, C.L.3
Diekmann, D.4
Hall, A.5
-
27
-
-
0035798097
-
Mammalian TOR: A homeostatic ATP sensor
-
Dennis, P. B. et al. Mammalian TOR: a homeostatic ATP sensor. Science 294, 1102-1105 (2001).
-
(2001)
Science
, vol.294
, pp. 1102-1105
-
-
Dennis, P.B.1
-
28
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp, T. R., Bernards, R. & Agami, R. A system for stable expression of short interfering RNAs in mammalian cells. Science 296, 550-553 (2002).
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
29
-
-
0033777308
-
Determination of GTP loading on Rac and Cdc42 in platelets and fibroblasts
-
Azim, A. C., Barkalow, K. L. & Hartwig, J. H. Determination of GTP loading on Rac and Cdc42 in platelets and fibroblasts. Methods Enzymol. 325, 257-263 (2000).
-
(2000)
Methods Enzymol.
, vol.325
, pp. 257-263
-
-
Azim, A.C.1
Barkalow, K.L.2
Hartwig, J.H.3
-
30
-
-
0034623005
-
T-Coffee: A novel method for fast and accurate multiple sequence alignment
-
Notredame, C., Higgins, D. G. & Heringa, J. T-Coffee: A novel method for fast and accurate multiple sequence alignment. J. Mol. Biol. 302, 205-217 (2000).
-
(2000)
J. Mol. Biol.
, vol.302
, pp. 205-217
-
-
Notredame, C.1
Higgins, D.G.2
Heringa, J.3
|