Cross-talk between sirtuin and mammalian target of rapamycin complex 1 (mTORC1) signaling in the regulation of S6 kinase 1 (S6K1) phosphorylation

Journal of Biological Chemistry

Volumn 289, Issue 19, 2014, Pages 13132-13141

  Hong, Sungki ^a   Zhao, Bin ^d   Lombard, David B ^b,c   Fingar, Diane C ^b   Inoki, Ken ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^d ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; ENZYMES; PHOSPHORYLATION; SUBSTRATES;

C-TERMINAL REGIONS; CELLULAR PROCESS; HISTONE DEACETYLASES; MAMMALIAN TARGET; MAMMALIAN TARGET OF RAPAMYCIN (MTOR); PHOSPHORYLATION SITES; POST-TRANSLATIONAL MODIFICATIONS; PROTEIN SYNTHESIS;

ACETYLATION;

HISTONE DEACETYLASE 3; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; RAPTOR PROTEIN; S6 KINASE; SCAFFOLD PROTEIN; SIRTUIN 1; SIRTUIN 2; THREONINE; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HUMAN CELL; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ACETYLATION; MTOR; MTOR COMPLEX (MTORC); PHOSPHORYLATION; RAPAMYCIN; S6 KINASE; SIRT1; SIRTUINS;

ACETYLATION; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; MULTIPROTEIN COMPLEXES; MUTATION; PHOSPHORYLATION; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; SIRTUIN 1; SIRTUIN 2; TOR SERINE-THREONINE KINASES;

EID: 84900404392     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.520734     Document Type: Article

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