Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB

Molecular Cell

Volumn 22, Issue 2, 2006, Pages 159-168

  Sarbassov, Dos D ^a,b   Ali, Siraj M ^a,b   Sengupta, Shomit ^a,b   Sheen, Joon Ho ^a,b   Hsu, Peggy P ^a,b   Bagley, Alex F ^a,b   Markhard, Andrew L ^a,b   Sabatini, David M ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

CELLCYCLE; CHEMBIO; SIGNALING

Indexed keywords

ANTINEOPLASTIC AGENT; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; RAPAMYCIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DEATH; CELL STRAIN HEK293; CELL TYPE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FEMALE; HELA CELL; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; HELA CELLS; HT29 CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; JURKAT CELLS; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PHOSPHORYLATION; PRECIPITIN TESTS; PROTO-ONCOGENE PROTEINS C-AKT; RETROVIRIDAE; SIGNAL TRANSDUCTION; SIROLIMUS; TIME FACTORS; TRANS-ACTIVATORS; TRANSPLANTATION, HETEROLOGOUS;

RAPTORES;

EID: 33646023695     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2006.03.029     Document Type: Article

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