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Volumn 77, Issue 10, 2010, Pages 855-860

Regulation of ion channels by secreted Klotho: Mechanisms and implications

Author keywords

Galectin; N glycan; ROMK; Sialidase; TRPC6; TRPV5

Indexed keywords

GALECTIN 1; GLYCAN; INSULIN; ION CHANNEL; KLOTHO PROTEIN; SIALIC ACID; SOMATOMEDIN; VANILLOID RECEPTOR 5;

EID: 77951871631     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2010.73     Document Type: Short Survey
Times cited : (66)

References (39)
  • 1
    • 0030724491 scopus 로고    scopus 로고
    • Mutation of the mouse klotho gene leads to a syndrome resembling aging
    • Kuro-o M, Matsumura Y, Aizawa H et al. Mutation of the mouse klotho gene leads to a syndrome resembling aging. Nature 1997; 390: 45-51.
    • (1997) Nature , vol.390 , pp. 45-51
    • Kuro-O, M.1    Matsumura, Y.2    Aizawa, H.3
  • 2
    • 24944481544 scopus 로고    scopus 로고
    • Suppression of aging in mice by the hormone Klotho
    • Kurosu H, Yamamoto M, Clark JD et al. Suppression of aging in mice by the hormone Klotho. Science 2005; 309: 1829-1833.
    • (2005) Science , vol.309 , pp. 1829-1833
    • Kurosu, H.1    Yamamoto, M.2    Clark, J.D.3
  • 3
    • 0037135232 scopus 로고    scopus 로고
    • Identification of a novel mouse membrane-bound family 1 glycosidase-like protein, which carries an atypical active site structure
    • Ito S, Fujimori T, Hayashizaki Y et al. Identification of a novel mouse membrane-bound family 1 glycosidase-like protein, which carries an atypical active site structure. Biochim Biophys Acta 2002; 1576: 341-345.
    • (2002) Biochim Biophys Acta , vol.1576 , pp. 341-345
    • Ito, S.1    Fujimori, T.2    Hayashizaki, Y.3
  • 4
    • 2342610541 scopus 로고    scopus 로고
    • Secreted Klotho protein in sera and CSF: Implication for post-translational cleavage in release of Klotho protein from cell membrane
    • Imura A, Iwano A, Tohyama O et al. Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane. FEBS Lett 2004; 565: 143-147.
    • (2004) FEBS Lett , vol.565 , pp. 143-147
    • Imura, A.1    Iwano, A.2    Tohyama, O.3
  • 5
    • 38049144010 scopus 로고    scopus 로고
    • Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17
    • Chen CD, Podvin S, Gillespie E et al. Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17. Proc Natl Acad Sci USA 2007; 104: 19796-19801.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 19796-19801
    • Chen, C.D.1    Podvin, S.2    Gillespie, E.3
  • 8
    • 1642352496 scopus 로고    scopus 로고
    • Klotho is a novel b-glucuronidase capable of hydrolyzing steroid b-glucuronides
    • Tohyama O, Imura A, Iwano A et al. Klotho is a novel b-glucuronidase capable of hydrolyzing steroid b-glucuronides. J Biol Chem 2004; 279: 9777-9784.
    • (2004) J Biol Chem , vol.279 , pp. 9777-9784
    • Tohyama, O.1    Imura, A.2    Iwano, A.3
  • 9
    • 47749148805 scopus 로고    scopus 로고
    • Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1
    • Cha SK, Ortega B, Kurosu H et al. Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1. Proc Natl Acad Sci USA 2008; 105: 9805-9810.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9805-9810
    • Cha, S.K.1    Ortega, B.2    Kurosu, H.3
  • 10
    • 67649834455 scopus 로고    scopus 로고
    • Reguation of ROMK1 channel and renal K+ excretion by Klotho
    • Cha SK, Hu MC, Kurosu H et al. Reguation of ROMK1 channel and renal K+ excretion by Klotho. Mol Pharmacol 2009; 76: 38-46.
    • (2009) Mol Pharmacol , vol.76 , pp. 38-46
    • Cha, S.K.1    Hu, M.C.2    Kurosu, H.3
  • 11
    • 27144440831 scopus 로고    scopus 로고
    • The b-glucuronidase klotho hydrolyzes and activates the TRPV5 channel
    • Chang Q, Hoefs S, van der Kemp AW et al. The b-glucuronidase klotho hydrolyzes and activates the TRPV5 channel. Science 2005; 310: 490-493.
    • (2005) Science , vol.310 , pp. 490-493
    • Chang, Q.1    Hoefs, S.2    Van Der Kemp, A.W.3
  • 13
    • 34247610845 scopus 로고    scopus 로고
    • Heparan sulphate proteoglycans fine-tune mammalian physiology
    • Bishop JR, Schuksz M, Esko JD. Heparan sulphate proteoglycans fine-tune mammalian physiology. Nature 2007; 446: 1030-1037.
    • (2007) Nature , vol.446 , pp. 1030-1037
    • Bishop, J.R.1    Schuksz, M.2    Esko, J.D.3
  • 14
    • 0035825644 scopus 로고    scopus 로고
    • Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation
    • Demetriou M, Granovsky M, Quaggin S et al. Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation. Nature 2001; 409: 733-739.
    • (2001) Nature , vol.409 , pp. 733-739
    • Demetriou, M.1    Granovsky, M.2    Quaggin, S.3
  • 15
    • 6044239186 scopus 로고    scopus 로고
    • Regulation of cytokine receptors by Golgi N-glycans processing and endocytosis
    • Partridge EA, Le Roy C, Di Guglielmo GM et al. Regulation of cytokine receptors by Golgi N-glycans processing and endocytosis. Science 2004; 306: 120-124.
    • (2004) Science , vol.306 , pp. 120-124
    • Partridge, E.A.1    Le Roy, C.2    Di Guglielmo, G.M.3
  • 16
    • 0026069647 scopus 로고
    • Biosynthesis and function of N-and O-substituted sialic acids
    • Schauer R. Biosynthesis and function of N-and O-substituted sialic acids. Glycobiology 1991; 1: 449-452.
    • (1991) Glycobiology , vol.1 , pp. 449-452
    • Schauer, R.1
  • 17
    • 31144466590 scopus 로고    scopus 로고
    • Identification of linkage-specific sequence motifs in sialyltransferases
    • Patel RY, Balaji PV. Identification of linkage-specific sequence motifs in sialyltransferases. Glycobiology 2006; 16: 108-116.
    • (2006) Glycobiology , vol.16 , pp. 108-116
    • Patel, R.Y.1    Balaji, P.V.2
  • 18
    • 0027965708 scopus 로고
    • Galectins: Structure and function of a large family of animal lectins
    • Barondes SH, Cooper DN, Gitt MA et al. Galectins: structure and function of a large family of animal lectins. J Biol Chem 1994; 269: 20807-20810.
    • (1994) J Biol Chem , vol.269 , pp. 20807-20810
    • Barondes, S.H.1    Cooper, D.N.2    Gitt, M.A.3
  • 19
    • 14044272136 scopus 로고    scopus 로고
    • Dimeric galectin-1 binds with high affinity to a2,3-sialylated and non-sialylated terminal N-acetyllactosamine units on surface-bound extended glycans
    • Leppanen A, Stowell S, Blixt O et al. Dimeric galectin-1 binds with high affinity to a2,3-sialylated and non-sialylated terminal N-acetyllactosamine units on surface-bound extended glycans. J Biol Chem 2005; 280: 5549-5562.
    • (2005) J Biol Chem , vol.280 , pp. 5549-5562
    • Leppanen, A.1    Stowell, S.2    Blixt, O.3
  • 20
    • 29244449332 scopus 로고    scopus 로고
    • Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes
    • Ohtsubo K, Takamatsu S, Minowa MT et al. Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes. Cell 2005; 123: 1307-1321.
    • (2005) Cell , vol.123 , pp. 1307-1321
    • Ohtsubo, K.1    Takamatsu, S.2    Minowa, M.T.3
  • 21
    • 55249119775 scopus 로고    scopus 로고
    • The Klotho gene family and the endocrine fibroblast growth factors
    • Kurosu H, Kuro-o M. The Klotho gene family and the endocrine fibroblast growth factors. Curr Opin Nephrol Hypertens 2008; 17: 368-372.
    • (2008) Curr Opin Nephrol Hypertens , vol.17 , pp. 368-372
    • Kurosu, H.1    Kuro-O, M.2
  • 22
    • 34250649644 scopus 로고    scopus 로고
    • The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasis
    • Razzaque MS, Lanske B. The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasis. J Endocrinol 2007; 194: 1-10.
    • (2007) J Endocrinol , vol.194 , pp. 1-10
    • Razzaque, M.S.1    Lanske, B.2
  • 23
    • 33646578195 scopus 로고    scopus 로고
    • Regulation of fibroblast growth factor-23 signaling by Klotho
    • Kurosu H, Ogawa Y, Miyoshi M et al. Regulation of fibroblast growth factor-23 signaling by Klotho. J Biol Chem 2006; 281: 6120-6123.
    • (2006) J Biol Chem , vol.281 , pp. 6120-6123
    • Kurosu, H.1    Ogawa, Y.2    Miyoshi, M.3
  • 24
    • 70350348267 scopus 로고    scopus 로고
    • The FGF23-Klotho axis: Endocrine regulation of phosphare homeostasis
    • Razzaque MS. The FGF23-Klotho axis: endocrine regulation of phosphare homeostasis. Nat Rev Endocrinol 2009; 5: 611-619.
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 611-619
    • Razzaque, M.S.1
  • 25
    • 0036150953 scopus 로고    scopus 로고
    • Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene
    • Yoshida T, Fujimori T, Nabeshima Y. Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene. Endocrinology 2002; 143: 683-689.
    • (2002) Endocrinology , vol.143 , pp. 683-689
    • Yoshida, T.1    Fujimori, T.2    Nabeshima, Y.3
  • 26
    • 64549096406 scopus 로고    scopus 로고
    • Klotho is a phosphaturic hormone: In vivo evidence
    • [abstract]
    • Hu MC, Zhang J, Shi M et al. Klotho is a phosphaturic hormone: in vivo evidence. J Am Sco Nephrol 2006; 17: 105a [abstract].
    • (2006) J Am Sco Nephrol , vol.17
    • Hu, M.C.1    Zhang, J.2    Shi, M.3
  • 29
    • 0036783531 scopus 로고    scopus 로고
    • Evidence for endocytosis of ROMK potassium channels via clathrin-coated vesicles
    • Zeng WZ, Babich V, Ortega B et al. Evidence for endocytosis of ROMK potassium channels via clathrin-coated vesicles. Am J Physiol 2002; 283: F630-F639.
    • (2002) Am J Physiol , vol.283
    • Zeng, W.Z.1    Babich, V.2    Ortega, B.3
  • 30
    • 45149092407 scopus 로고    scopus 로고
    • Protein kinase C inhibits caveolae-mediated endocytosis of TRPV5
    • Cha SK, Wu T, Huang CL. Protein kinase C inhibits caveolae-mediated endocytosis of TRPV5. Am J Physiol Renal Physiol 2008; 294: F1212-F1221.
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Cha, S.K.1    Wu, T.2    Huang, C.L.3
  • 31
    • 0036235099 scopus 로고    scopus 로고
    • In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage
    • Mitani H, Ishizaka N, Aizawa T et al. In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage. Hypertension 2002; 39: 838-843.
    • (2002) Hypertension , vol.39 , pp. 838-843
    • Mitani, H.1    Ishizaka, N.2    Aizawa, T.3
  • 32
    • 34250379991 scopus 로고    scopus 로고
    • Angiotensin II inhibits the ROMK-like small conductance K channel in renal cortical collecting duct during dietary potassium restriction
    • Wei Y, Zavilowitz B, Satlin LM et al. Angiotensin II inhibits the ROMK-like small conductance K channel in renal cortical collecting duct during dietary potassium restriction. J Biol Chem 2007; 282: 6455-6462.
    • (2007) J Biol Chem , vol.282 , pp. 6455-6462
    • Wei, Y.1    Zavilowitz, B.2    Satlin, L.M.3
  • 33
    • 77951801767 scopus 로고    scopus 로고
    • The anti-aging hormone Klotho regulates cell surface abundance of TRPC6
    • [abstract].
    • Cha SK, Kuroo M, Huang CL. The anti-aging hormone Klotho regulates cell surface abundance of TRPC6. J Am Soc Nephrol 2009 [abstract]. (Available online at http://www.asn-online.org).
    • (2009) J Am Soc Nephrol
    • Cha, S.K.1    Kuroo, M.2    Huang, C.L.3
  • 35
    • 20844461826 scopus 로고    scopus 로고
    • A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis
    • Winn MP, Conlon PJ, Lynn KL et al. A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. Science 2005; 308: 1801-1804.
    • (2005) Science , vol.308 , pp. 1801-1804
    • Winn, M.P.1    Conlon, P.J.2    Lynn, K.L.3
  • 36
    • 33845317604 scopus 로고    scopus 로고
    • TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling
    • Kuwahara K, Wang Y, McAnally J et al. TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling. J Clin Invest 2006; 116: 3114-3126.
    • (2006) J Clin Invest , vol.116 , pp. 3114-3126
    • Kuwahara, K.1    Wang, Y.2    McAnally, J.3
  • 37
    • 0034810211 scopus 로고    scopus 로고
    • Severely reduced production of klotho in human chronic renal failure kidney
    • Koh N, Fujimori T, Nishiguchi S et al. Severely reduced production of klotho in human chronic renal failure kidney. Biochem Biophys Res Commun 2001; 280: 1015-1020.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 1015-1020
    • Koh, N.1    Fujimori, T.2    Nishiguchi, S.3
  • 38
    • 33847781131 scopus 로고    scopus 로고
    • Amelioration of progreesive renal injury by genetic manipulation of Klotho gene
    • Haruna Y, Kashihara N, Satoh M et al. Amelioration of progreesive renal injury by genetic manipulation of Klotho gene. Proc Natl Acad Sci 2007; 104: 2331-2336.
    • (2007) Proc Natl Acad Sci , vol.104 , pp. 2331-2336
    • Haruna, Y.1    Kashihara, N.2    Satoh, M.3
  • 39
    • 34250803923 scopus 로고    scopus 로고
    • Alpha-Klotho as a regulator of calcium homeostasis
    • Imura A, Tsuji Y, Murata M et al. Alpha-Klotho as a regulator of calcium homeostasis. Science 2007; 316: 1615-1618.
    • (2007) Science , vol.316 , pp. 1615-1618
    • Imura, A.1    Tsuji, Y.2    Murata, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.