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Volumn 153, Issue 1, 2013, Pages 228-239

Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSYLMETHIONINE SYNTHASE; GLUCOSE; METFORMIN; METHIONINE; METHIONINE SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG;

EID: 84875738351     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2013.02.035     Document Type: Article
Times cited : (774)

References (70)
  • 2
    • 15544369658 scopus 로고    scopus 로고
    • Host-bacterial mutualism in the human intestine
    • DOI 10.1126/science.1104816
    • F. Bäckhed, R.E. Ley, J.L. Sonnenburg, D.A. Peterson, and J.I. Gordon Host-bacterial mutualism in the human intestine Science 307 2005 1915 1920 (Pubitemid 40404694)
    • (2005) Science , vol.307 , Issue.5717 , pp. 1915-1920
    • Backhed, F.1    Ley, R.E.2    Sonnenburg, J.L.3    Peterson, D.A.4    Gordon, J.I.5
  • 4
    • 0025228772 scopus 로고
    • Cobalamin-dependent methionine synthase
    • R.V. Banerjee, and R.G. Matthews Cobalamin-dependent methionine synthase FASEB J. 4 1990 1450 1459
    • (1990) FASEB J. , vol.4 , pp. 1450-1459
    • Banerjee, R.V.1    Matthews, R.G.2
  • 5
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • S. Brenner The genetics of Caenorhabditis elegans Genetics 77 1974 71 94
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 6
    • 0035186582 scopus 로고    scopus 로고
    • Oral hypoglycaemic drugs and gastrointestinal symptoms in diabetes mellitus
    • DOI 10.1046/j.1365-2036.2001.00896.x
    • P. Bytzer, N.J. Talley, M.P. Jones, and M. Horowitz Oral hypoglycaemic drugs and gastrointestinal symptoms in diabetes mellitus Aliment. Pharmacol. Ther. 15 2001 137 142 (Pubitemid 32055594)
    • (2001) Alimentary Pharmacology and Therapeutics , vol.15 , Issue.1 , pp. 137-142
    • Bytzer, P.1    Talley, N.J.2    Jones, M.P.3    Horowitz, M.4
  • 7
    • 37349018683 scopus 로고    scopus 로고
    • Gut microflora as a target for energy and metabolic homeostasis
    • DOI 10.1097/MCO.0b013e3282efdebb, PII 0007519720071100000013
    • P.D. Cani, and N.M. Delzenne Gut microflora as a target for energy and metabolic homeostasis Curr. Opin. Clin. Nutr. Metab. Care 10 2007 729 734 (Pubitemid 350293774)
    • (2007) Current Opinion in Clinical Nutrition and Metabolic Care , vol.10 , Issue.6 , pp. 729-734
    • Cani, P.D.1    Delzenne, N.M.2
  • 8
    • 77957226879 scopus 로고    scopus 로고
    • Drr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans
    • T.T. Ching, A.B. Paal, A. Mehta, L. Zhong, and A.L. Hsu drr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans Aging Cell 9 2010 545 557
    • (2010) Aging Cell , vol.9 , pp. 545-557
    • Ching, T.T.1    Paal, A.B.2    Mehta, A.3    Zhong, L.4    Hsu, A.L.5
  • 9
    • 79955896909 scopus 로고    scopus 로고
    • Gut microbiota and the pathogenesis of insulin resistance
    • N.M. Delzenne, and P.D. Cani Gut microbiota and the pathogenesis of insulin resistance Curr. Diab. Rep. 11 2011 154 159
    • (2011) Curr. Diab. Rep. , vol.11 , pp. 154-159
    • Delzenne, N.M.1    Cani, P.D.2
  • 10
    • 80054913827 scopus 로고    scopus 로고
    • Targeting gut microbiota in obesity: Effects of prebiotics and probiotics
    • N.M. Delzenne, A.M. Neyrinck, F. Backhed, and P.D. Cani Targeting gut microbiota in obesity: effects of prebiotics and probiotics Nat. Rev. Endocrinol. 7 2011 639 646
    • (2011) Nat. Rev. Endocrinol. , vol.7 , pp. 639-646
    • Delzenne, N.M.1    Neyrinck, A.M.2    Backhed, F.3    Cani, P.D.4
  • 11
    • 79953661884 scopus 로고    scopus 로고
    • Understanding the benefit of metformin use in cancer treatment
    • R.J. Dowling, P.J. Goodwin, and V. Stambolic Understanding the benefit of metformin use in cancer treatment BMC Med. 9 2011 33
    • (2011) BMC Med. , vol.9 , pp. 33
    • Dowling, R.J.1    Goodwin, P.J.2    Stambolic, V.3
  • 12
    • 0036021375 scopus 로고    scopus 로고
    • Genetic analysis of tissue aging in Caenorhabditis elegans: A role for heat-shock factor and bacterial proliferation
    • D. Garigan, A.L. Hsu, A.G. Fraser, R.S. Kamath, J. Ahringer, and C. Kenyon Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation Genetics 161 2002 1101 1112 (Pubitemid 34831435)
    • (2002) Genetics , vol.161 , Issue.3 , pp. 1101-1112
    • Garigan, D.1    Hsu, A.-L.2    Fraser, A.G.3    Kamath, R.S.4    Abringet, J.5    Kenyon, C.6
  • 14
    • 0034036321 scopus 로고    scopus 로고
    • Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans
    • D. Gems, and D.L. Riddle Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans Genetics 154 2000 1597 1610 (Pubitemid 30211244)
    • (2000) Genetics , vol.154 , Issue.4 , pp. 1597-1610
    • Gems, D.1    Riddle, D.L.2
  • 15
    • 72949117234 scopus 로고    scopus 로고
    • Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila
    • R.C. Grandison, M.D. Piper, and L. Partridge Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila Nature 462 2009 1061 1064
    • (2009) Nature , vol.462 , pp. 1061-1064
    • Grandison, R.C.1    Piper, M.D.2    Partridge, L.3
  • 17
    • 33645472504 scopus 로고    scopus 로고
    • New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen
    • M. Hansen, A.L. Hsu, A. Dillin, and C. Kenyon New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen PLoS Genet. 1 2005 119 128
    • (2005) PLoS Genet. , vol.1 , pp. 119-128
    • Hansen, M.1    Hsu, A.L.2    Dillin, A.3    Kenyon, C.4
  • 18
    • 0345107247 scopus 로고    scopus 로고
    • Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
    • S.A. Hawley, J. Boudeau, J.L. Reid, K.J. Mustard, L. Udd, T.P. Mäkelä, D.R. Alessi, and D.G. Hardie Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade J. Biol. 2 2003 28
    • (2003) J. Biol. , vol.2 , pp. 28
    • Hawley, S.A.1    Boudeau, J.2    Reid, J.L.3    Mustard, K.J.4    Udd, L.5    Mäkelä, T.P.6    Alessi, D.R.7    Hardie, D.G.8
  • 19
    • 35448970986 scopus 로고    scopus 로고
    • Influence of lactic acid bacteria on longevity of Caenorhabditis elegans and host defense against Salmonella enterica serovar Enteritidis
    • DOI 10.1128/AEM.00704-07
    • T. Ikeda, C. Yasui, K. Hoshino, K. Arikawa, and Y. Nishikawa Influence of lactic acid bacteria on longevity of Caenorhabditis elegans and host defense against salmonella enterica serovar enteritidis Appl. Environ. Microbiol. 73 2007 6404 6409 (Pubitemid 47623697)
    • (2007) Applied and Environmental Microbiology , vol.73 , Issue.20 , pp. 6404-6409
    • Ikeda, T.1    Yasui, C.2    Hoshino, K.3    Arikawa, K.4    Nishikawa, Y.5
  • 22
    • 77950200010 scopus 로고    scopus 로고
    • The genetics of ageing
    • C.J. Kenyon The genetics of ageing Nature 464 2010 504 512
    • (2010) Nature , vol.464 , pp. 504-512
    • Kenyon, C.J.1
  • 25
    • 0034735920 scopus 로고    scopus 로고
    • Caenorhabditis elegans is a model host for Salmonella typhimurium
    • DOI 10.1016/S0960-9822(00)00833-2
    • A. Labrousse, S. Chauvet, C. Couillault, C.L. Kurz, and J.J. Ewbank Caenorhabditis elegans is a model host for Salmonella typhimurium Curr. Biol. 10 2000 1543 1545 (Pubitemid 32003650)
    • (2000) Current Biology , vol.10 , Issue.23 , pp. 1543-1545
    • Labrousse, A.1    Chauvet, S.2    Couillault, C.3    Leopold Kurz, C.4    Ewbank, J.J.5
  • 26
    • 70350365110 scopus 로고    scopus 로고
    • Glucose shortens the lifespan of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression
    • S.J. Lee, C.T. Murphy, and C. Kenyon Glucose shortens the lifespan of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression Cell Metab. 10 2009 379 391
    • (2009) Cell Metab. , vol.10 , pp. 379-391
    • Lee, S.J.1    Murphy, C.T.2    Kenyon, C.3
  • 28
    • 77952908744 scopus 로고    scopus 로고
    • A neuromedin U receptor acts with the sensory system to modulate food type-dependent effects on C. elegans lifespan
    • W. Maier, B. Adilov, M. Regenass, and J. Alcedo A neuromedin U receptor acts with the sensory system to modulate food type-dependent effects on C. elegans lifespan PLoS Biol. 8 2010 e1000376
    • (2010) PLoS Biol. , vol.8 , pp. 1000376
    • Maier, W.1    Adilov, B.2    Regenass, M.3    Alcedo, J.4
  • 29
    • 50649099122 scopus 로고    scopus 로고
    • Aging and survival: The genetics of lifespan extension by dietary restriction
    • W. Mair, and A. Dillin Aging and survival: the genetics of lifespan extension by dietary restriction Annu. Rev. Biochem. 77 2008 727 754
    • (2008) Annu. Rev. Biochem. , vol.77 , pp. 727-754
    • Mair, W.1    Dillin, A.2
  • 35
    • 11244333118 scopus 로고    scopus 로고
    • A mathematical model of the folate cycle: New insights into folate homeostasis
    • DOI 10.1074/jbc.M410818200
    • H.F. Nijhout, M.C. Reed, P. Budu, and C.M. Ulrich A mathematical model of the folate cycle: new insights into folate homeostasis J. Biol. Chem. 279 2004 55008 55016 (Pubitemid 40066492)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.53 , pp. 55008-55016
    • Nijhout, H.F.1    Reed, M.C.2    Budu, P.3    Ulrich, C.M.4
  • 36
    • 77649311383 scopus 로고    scopus 로고
    • Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1
    • B. Onken, and M. Driscoll Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1 PLoS ONE 5 2010 e8758
    • (2010) PLoS ONE , vol.5 , pp. 8758
    • Onken, B.1    Driscoll, M.2
  • 38
    • 83555173345 scopus 로고    scopus 로고
    • Gut microbiota as a candidate for lifespan extension: An ecological/evolutionary perspective targeted on living organisms as metaorganisms
    • E. Ottaviani, N. Ventura, M. Mandrioli, M. Candela, A. Franchini, and C. Franceschi Gut microbiota as a candidate for lifespan extension: an ecological/evolutionary perspective targeted on living organisms as metaorganisms Biogerontology 12 2011 599 609
    • (2011) Biogerontology , vol.12 , pp. 599-609
    • Ottaviani, E.1    Ventura, N.2    Mandrioli, M.3    Candela, M.4    Franchini, A.5    Franceschi, C.6
  • 39
    • 84884211823 scopus 로고    scopus 로고
    • Targeting metabolism for cancer treatment and prevention: Metformin, an old drug with multi-faceted effects
    • 10.1038/onc.2012.181
    • M.A. Pierotti, F. Berrino, M. Gariboldi, C. Melani, A. Mogavero, T. Negri, P. Pasanisi, and S. Pilotti Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects Oncogene 2012 10.1038/onc.2012.181
    • (2012) Oncogene
    • Pierotti, M.A.1    Berrino, F.2    Gariboldi, M.3    Melani, C.4    Mogavero, A.5    Negri, T.6    Pasanisi, P.7    Pilotti, S.8
  • 40
    • 47949130628 scopus 로고    scopus 로고
    • Mechanisms underlying saturable intestinal absorption of metformin
    • W.R. Proctor, D.L. Bourdet, and D.R. Thakker Mechanisms underlying saturable intestinal absorption of metformin Drug Metab. Dispos. 36 2008 1650 1658
    • (2008) Drug Metab. Dispos. , vol.36 , pp. 1650-1658
    • Proctor, W.R.1    Bourdet, D.L.2    Thakker, D.R.3
  • 41
    • 84858251477 scopus 로고    scopus 로고
    • Prebiotic fiber increases hepatic acetyl CoA carboxylase phosphorylation and suppresses glucose-dependent insulinotropic polypeptide secretion more effectively when used with metformin in obese rats
    • K.A. Pyra, D.C. Saha, and R.A. Reimer Prebiotic fiber increases hepatic acetyl CoA carboxylase phosphorylation and suppresses glucose-dependent insulinotropic polypeptide secretion more effectively when used with metformin in obese rats J. Nutr. 142 2012 213 220
    • (2012) J. Nutr. , vol.142 , pp. 213-220
    • Pyra, K.A.1    Saha, D.C.2    Reimer, R.A.3
  • 42
    • 33847195790 scopus 로고    scopus 로고
    • Effects of metformin or rosiglitazone on serum concentrations of homocysteine, folate, and vitamin B12 in patients with type 2 diabetes mellitus
    • M. Sahin, N.B. Tutuncu, D. Ertugrul, N. Tanaci, and N.D. Guvener Effects of metformin or rosiglitazone on serum concentrations of homocysteine, folate, and vitamin B12 in patients with type 2 diabetes mellitus J. Diabetes Complications 21 2007 118 123
    • (2007) J. Diabetes Complications , vol.21 , pp. 118-123
    • Sahin, M.1    Tutuncu, N.B.2    Ertugrul, D.3    Tanaci, N.4    Guvener, N.D.5
  • 43
    • 43449139142 scopus 로고    scopus 로고
    • Altered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q
    • DOI 10.1111/j.1474-9726.2008.00378.x
    • R. Saiki, A.L. Lunceford, T. Bixler, P. Dang, W. Lee, S. Furukawa, P.L. Larsen, and C.F. Clarke Altered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q Aging Cell 7 2008 291 304 (Pubitemid 351663899)
    • (2008) Aging Cell , vol.7 , Issue.3 , pp. 291-304
    • Saiki, R.1    Lunceford, A.L.2    Bixler, T.3    Dang, P.4    Lee, W.5    Furukawa, S.6    Larsen, P.L.7    Clarke, C.F.8
  • 45
    • 84867621125 scopus 로고    scopus 로고
    • Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in Drosophila
    • C. Slack, A. Foley, and L. Partridge Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in Drosophila PLoS ONE 7 2012 e47699
    • (2012) PLoS ONE , vol.7 , pp. 47699
    • Slack, C.1    Foley, A.2    Partridge, L.3
  • 46
    • 44649170501 scopus 로고    scopus 로고
    • Age- and calorie-independent lifespan extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans
    • E.D. Smith, T.L. Kaeberlein, B.T. Lydum, J. Sager, K.L. Welton, B.K. Kennedy, and M. Kaeberlein Age- and calorie-independent lifespan extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans BMC Dev. Biol. 8 2008 49
    • (2008) BMC Dev. Biol. , vol.8 , pp. 49
    • Smith, E.D.1    Kaeberlein, T.L.2    Lydum, B.T.3    Sager, J.4    Welton, K.L.5    Kennedy, B.K.6    Kaeberlein, M.7
  • 47
    • 80052774197 scopus 로고    scopus 로고
    • Lactobacillus plantarum promotes Drosophila systemic growth by modulating hormonal signals through TOR-dependent nutrient sensing
    • G. Storelli, A. Defaye, B. Erkosar, P. Hols, J. Royet, and F. Leulier Lactobacillus plantarum promotes Drosophila systemic growth by modulating hormonal signals through TOR-dependent nutrient sensing Cell Metab. 14 2011 403 414
    • (2011) Cell Metab. , vol.14 , pp. 403-414
    • Storelli, G.1    Defaye, A.2    Erkosar, B.3    Hols, P.4    Royet, J.5    Leulier, F.6
  • 49
    • 36148982248 scopus 로고    scopus 로고
    • Glycemic index and glycemic load: Measurement issues and their effect on diet-disease relationships
    • B.J. Venn, and T.J. Green Glycemic index and glycemic load: measurement issues and their effect on diet-disease relationships Eur. J. Clin. Nutr. 61 Suppl 1 2007 S122 S131
    • (2007) Eur. J. Clin. Nutr. , vol.61 , Issue.SUPPL. 1
    • Venn, B.J.1    Green, T.J.2
  • 52
    • 74049092331 scopus 로고    scopus 로고
    • Mortality shifts in Caenorhabditis elegans: Remembrance of conditions past
    • D. Wu, S.L. Rea, J.R. Cypser, and T.E. Johnson Mortality shifts in Caenorhabditis elegans: remembrance of conditions past Aging Cell 8 2009 666 675
    • (2009) Aging Cell , vol.8 , pp. 666-675
    • Wu, D.1    Rea, S.L.2    Cypser, J.R.3    Johnson, T.E.4
  • 53
    • 49649111434 scopus 로고    scopus 로고
    • Role of microorganisms in the evolution of animals and plants: The hologenome theory of evolution
    • I. Zilber-Rosenberg, and E. Rosenberg Role of microorganisms in the evolution of animals and plants: the hologenome theory of evolution FEMS Microbiol. Rev. 32 2008 723 735
    • (2008) FEMS Microbiol. Rev. , vol.32 , pp. 723-735
    • Zilber-Rosenberg, I.1    Rosenberg, E.2
  • 54
    • 0014674485 scopus 로고
    • A complementation analysis of the restriction and modification of DNA in Escherichia coli
    • H.W. Boyer, and D. Roulland-Dussoix A complementation analysis of the restriction and modification of DNA in Escherichia coli J. Mol. Biol. 41 1969 459 472
    • (1969) J. Mol. Biol. , vol.41 , pp. 459-472
    • Boyer, H.W.1    Roulland-Dussoix, D.2
  • 55
    • 33845977697 scopus 로고    scopus 로고
    • Quantitative analysis of s-adenosylmethionine and s-adenosylhomocysteine in neurulation-stage mouse embryos by liquid chromatography tandem mass spectrometry
    • DOI 10.1016/j.jchromb.2006.07.012, PII S1570023206005538
    • K.A. Burren, K. Mills, A.J. Copp, and N.D. Greene Quantitative analysis of s-adenosylmethionine and s-adenosylhomocysteine in neurulation-stage mouse embryos by liquid chromatography tandem mass spectrometry J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 844 2006 112 118 (Pubitemid 46048615)
    • (2006) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.844 , Issue.1 , pp. 112-118
    • Burren, K.A.1    Mills, K.2    Copp, A.J.3    Greene, N.D.E.4
  • 56
    • 24644467263 scopus 로고    scopus 로고
    • Comprehensive metabolic profiling of mono- and polyglutamated folates and their precursors in plant and animal tissue using liquid chromatography/ negative ion electrospray ionisation tandem mass spectrometry
    • DOI 10.1002/rcm.2074
    • L.C. Garratt, C.A. Ortori, G.A. Tucker, F. Sablitzky, M.J. Bennett, and D.A. Barrett Comprehensive metabolic profiling of mono- and polyglutamated folates and their precursors in plant and animal tissue using liquid chromatography/negative ion electrospray ionisation tandem mass spectrometry Rapid Commun. Mass Spectrom. 19 2005 2390 2398 (Pubitemid 41284988)
    • (2005) Rapid Communications in Mass Spectrometry , vol.19 , Issue.17 , pp. 2390-2398
    • Garratt, L.C.1    Ortori, C.A.2    Tucker, G.A.3    Sablitzky, F.4    Bennett, M.J.5    Barrett, D.A.6
  • 57
    • 0027251266 scopus 로고
    • The Escherichia coli K-12 'wild types' W3110 and MG1655 have an rph frameshift mutation that leads to pyrimidine starvation due to low pyrE expression levels
    • K.F. Jensen The Escherichia coli K-12 "wild types" W3110 and MG1655 have an rph frameshift mutation that leads to pyrimidine starvation due to low pyrE expression levels J. Bacteriol. 175 1993 3401 3407 (Pubitemid 23163383)
    • (1993) Journal of Bacteriology , vol.175 , Issue.11 , pp. 3401-3407
    • Jensen, K.F.1
  • 58
    • 0035229245 scopus 로고    scopus 로고
    • Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans
    • RESEARCH0002
    • R.S. Kamath, M. Martinez-Campos, P. Zipperlen, A.G. Fraser, and J. Ahringer Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans Genome Biol. 2 2001 RESEARCH0002
    • (2001) Genome Biol. , vol.2
    • Kamath, R.S.1    Martinez-Campos, M.2    Zipperlen, P.3    Fraser, A.G.4    Ahringer, J.5
  • 59
    • 70449401564 scopus 로고    scopus 로고
    • Improved trimethoprim-resistance cassette for prokaryotic selections
    • Y.B. Kim Improved trimethoprim-resistance cassette for prokaryotic selections J. Biosci. Bioeng. 108 2009 441 445
    • (2009) J. Biosci. Bioeng. , vol.108 , pp. 441-445
    • Kim, Y.B.1
  • 61
    • 0037016442 scopus 로고    scopus 로고
    • Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q
    • DOI 10.1126/science.1064653
    • P.L. Larsen, and C.F. Clarke Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q Science 295 2002 120 123 (Pubitemid 34052359)
    • (2002) Science , vol.295 , Issue.5552 , pp. 120-123
    • Larsen, P.L.1    Clarke, C.F.2
  • 62
    • 33751203889 scopus 로고    scopus 로고
    • Dietary deprivation extends lifespan in Caenorhabditis elegans
    • DOI 10.1111/j.1474-9726.2006.00241.x
    • G.D. Lee, M.A. Wilson, M. Zhu, C.A. Wolkow, R. de Cabo, D.K. Ingram, and S. Zou Dietary deprivation extends lifespan in Caenorhabditis elegans Aging Cell 5 2006 515 524 (Pubitemid 44782620)
    • (2006) Aging Cell , vol.5 , Issue.6 , pp. 515-524
    • Lee, G.D.1    Wilson, M.A.2    Zhu, M.3    Wolkow, C.A.4    De Cabo, R.5    Ingram, D.K.6    Zou, S.7
  • 63
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transform
    • H. Li, and R. Durbin Fast and accurate short read alignment with Burrows-Wheeler transform Bioinformatics 25 2009 1754 1760
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 64
    • 0026741550 scopus 로고
    • Structures of the rfaB, rfaI, rfaJ, and rfaS genes of Escherichia coli K-12 and their roles in assembly of the lipopolysaccharide core
    • E. Pradel, C.T. Parker, and C.A. Schnaitman Structures of the rfaB, rfaI, rfaJ, and rfaS genes of Escherichia coli K-12 and their roles in assembly of the lipopolysaccharide core J. Bacteriol. 174 1992 4736 4745
    • (1992) J. Bacteriol. , vol.174 , pp. 4736-4745
    • Pradel, E.1    Parker, C.T.2    Schnaitman, C.A.3
  • 65
    • 0017128621 scopus 로고
    • Similarities between plasmids of the P-incompatibility group derived from different bacterial genera
    • V.A. Stanisich, and J.M. Ortiz Similarities between plasmids of the P-incompatibility group derived from different bacterial genera J. Gen. Microbiol. 94 1976 281 289
    • (1976) J. Gen. Microbiol. , vol.94 , pp. 281-289
    • Stanisich, V.A.1    Ortiz, J.M.2
  • 66
    • 0025283867 scopus 로고
    • Use of T7 RNA polymerase to direct expression of cloned genes
    • DOI 10.1016/0076-6879(90)85008-C
    • F.W. Studier, A.H. Rosenberg, J.J. Dunn, and J.W. Dubendorff Use of T7 RNA polymerase to direct expression of cloned genes Methods Enzymol. 185 1990 60 89 (Pubitemid 20219811)
    • (1990) Methods in Enzymology , vol.185 , pp. 60-89
    • Studier, F.W.1    Rosenberg, A.H.2    Dunn, J.J.3    Dubendorff, J.W.4
  • 67
    • 0020526269 scopus 로고
    • Heteroduplex analysis of P-plasmid evolution: The role of insertion and deletion of transposable elements
    • R. Villarroel, R.W. Hedges, R. Maenhaut, J. Leemans, G. Engler, M. Van Montagu, and J. Schell Heteroduplex analysis of P-plasmid evolution: the role of insertion and deletion of transposable elements Mol. Gen. Genet. 189 1983 390 399 (Pubitemid 13078657)
    • (1983) Molecular and General Genetics , vol.189 , Issue.3 , pp. 390-399
    • Villarroel, R.1    Hedges, R.W.2    Maenhaut, R.3
  • 68
    • 35548950179 scopus 로고    scopus 로고
    • Identification of potential therapeutic drugs for Huntington's disease using Caenorhabditis elegans
    • C. Voisine, H. Varma, N. Walker, E.A. Bates, B.R. Stockwell, and A.C. Hart Identification of potential therapeutic drugs for Huntington's disease using Caenorhabditis elegans PLoS ONE 2 2007 e504
    • (2007) PLoS ONE , vol.2 , pp. 504
    • Voisine, C.1    Varma, H.2    Walker, N.3    Bates, E.A.4    Stockwell, B.R.5    Hart, A.C.6
  • 69
    • 79958115671 scopus 로고    scopus 로고
    • Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst
    • J. Xia, and D.S. Wishart Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst Nat. Protoc. 6 2011 743 760
    • (2011) Nat. Protoc. , vol.6 , pp. 743-760
    • Xia, J.1    Wishart, D.S.2
  • 70
    • 33748502748 scopus 로고    scopus 로고
    • Role of N-acetylglucosamine within core lipopolysaccharide of several species of Gram-negative bacteria in targeting the DC-SIGN (CD209)
    • P. Zhang, S. Snyder, P. Feng, P. Azadi, S. Zhang, S. Bulgheresi, K.E. Sanderson, J. He, J. Klena, and T. Chen Role of N-acetylglucosamine within core lipopolysaccharide of several species of gram-negative bacteria in targeting the DC-SIGN (CD209) J. Immunol. 177 2006 4002 4011 (Pubitemid 44359933)
    • (2006) Journal of Immunology , vol.177 , Issue.6 , pp. 4002-4011
    • Zhang, P.1    Snyder, S.2    Feng, P.3    Azadi, P.4    Zhang, S.5    Bulgheresi, S.6    Sanderson, K.E.7    He, J.8    Klena, J.9    Chen, T.10


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