SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks

Cell Metabolism

Volumn 18, Issue 6, 2013, Pages 920-933

  Rardin, Matthew J ^a   He, Wenjuan ^b   Nishida, Yuya ^b   Newman, John C ^b   Carrico, Chris ^b   Danielson, Steven R ^a   Guo, Ailan ^c   Gut, Philipp ^b   Sahu, Alexandria K ^a   Li, Biao ^a   Uppala, Radha ^d   Fitch, Mark ^e   Riiff, Timothy ^f   Zhu, Lei ^b   Zhou, Jing ^c   Mulhern, Daniel ^c   Stevens, Robert D ^g   Ilkayeva, Olga R ^g   Newgard, Christopher B ^g   Jacobson, Matthew P ^b   Hellerstein, Marc ^e,f   Goetzman, Eric S ^d   Gibson, Bradford W ^a,b   Verdin, Eric ^b   more..

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CELL SIGNALING TECHNOLOGY   (United States)

^d CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f KINEMED INC   (United States)

^g DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COA SYNTHASE 2; 3 HYDROXYBUTYRIC ACID; ACYLCARNITINE; ENZYME; GLUTAMIC ACID; LYSINE; SIRTUIN 5; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; ENZYME ACTIVITY; ENZYME REGULATION; FATTY ACID METABOLISM; FATTY ACID OXIDATION; IN VITRO STUDY; IN VIVO STUDY; KETOGENESIS; LIVER MITOCHONDRION; LYSINE SUCCINYLATION; METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEOMICS;

AMINO ACID MOTIFS; ANIMALS; CARNITINE; CELL LINE; HUMANS; HYDROXYBUTYRATES; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; KETONE BODIES; LYSINE; MALE; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, KNOCKOUT; MITOCHONDRIA, LIVER; MITOCHONDRIAL PROTEINS; MUTATION; OXIDATION-REDUCTION; SIRTUINS; SUCCINATES;

EID: 84889636259     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2013.11.013     Document Type: Article

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