Transduction of receptor signals by β-arrestins

Science

Volumn 308, Issue 5721, 2005, Pages 512-517

  Lefkowitz, Robert J ^a,b   Shenoy, Sudha K ^b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IONS; MEMBRANES; MOLECULES; PROTEINS; SIGNAL PROCESSING; SIGNALING;

PLASMA MEMBRANES; RECEPTOR SIGNALS; SIGNALING PATHWAYS; TRANSMEMBRANES;

CELLS;

ADAPTOR PROTEIN; APOPTOSIS INHIBITOR; BETA ARRESTIN; BETA ARRESTIN 1; BETA ARRESTIN 2; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE PROTEIN; MEMBRANE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

BIOCHEMISTRY; BIOLOGY;

APOPTOSIS; CELL FUNCTION; CELL MEMBRANE; CELL MOTILITY; CHEMOTAXIS; CONFORMATIONAL TRANSITION; CYTOPLASM; ENDOCYTOSIS; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; APOPTOSIS; ARRESTINS; CELL MOVEMENT; CHEMOTAXIS; ENDOCYTOSIS; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN-TYROSINE KINASES; RECEPTORS, G-PROTEIN-COUPLED; SECOND MESSENGER SYSTEMS; SIGNAL TRANSDUCTION;

EID: 17644402459     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1109237     Document Type: Review

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67. We thank E. Hall and D. Addison for excellent secretarial assistance. R.J.L. is a HHMI investigator. NIH Grants HL 15037 and HL 70631 (to R.J.L.) supported this work.