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Volumn 7, Issue 4, 2006, Pages 225-235

Recent advances in growth hormone signaling

Author keywords

Growth hormone (GH); Janus kinase 2 (JAK2); Mitogen activated protein kinase (MAPK); Protein tyrosine phosphatase (PTP); Signal transducers and activators of transcription (Stats); Suppressor of cytokine signaling (SOCS)

Indexed keywords

ACTIN; GROWTH HORMONE; GROWTH HORMONE RECEPTOR; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; STAT PROTEIN;

EID: 33947174144     PISSN: 13899155     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11154-007-9025-5     Document Type: Review
Times cited : (183)

References (99)
  • 1
    • 0030050701 scopus 로고    scopus 로고
    • Binding in the growth hormone receptor complex
    • Wells JA. Binding in the growth hormone receptor complex. Proc Natl Acad Sci U S A 1996;93:1-6.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 1-6
    • Wells, J.A.1
  • 2
    • 0032570710 scopus 로고    scopus 로고
    • Activation of chimeric and full-length growth hormone receptors by growth hormone receptor monoclonal antibodies. A specific conformational change may be required for full-length receptor signaling
    • Rowlinson SW, Behncken SN, Rowland JE, Clarkson RW, Strasburger CJ, Wu Z, et al. Activation of chimeric and full-length growth hormone receptors by growth hormone receptor monoclonal antibodies. A specific conformational change may be required for full-length receptor signaling. J Biol Chem 1998; 273:5307-14.
    • (1998) J Biol Chem , vol.273 , pp. 5307-5314
    • Rowlinson, S.W.1    Behncken, S.N.2    Rowland, J.E.3    Clarkson, R.W.4    Strasburger, C.J.5    Wu, Z.6
  • 3
    • 0037162458 scopus 로고    scopus 로고
    • Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis
    • Gent J, van Kerkhof P, Roza M, Bu G, Strous GJ. Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis. Proc Natl Acad Sci U.S.A. 2002;99:9858-63.
    • (2002) Proc Natl Acad Sci U.S.A , vol.99 , pp. 9858-9863
    • Gent, J.1    van Kerkhof, P.2    Roza, M.3    Bu, G.4    Strous, G.J.5
  • 6
    • 0027936422 scopus 로고
    • Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase
    • VanderKuur JA, Wang X, Zhang L, Campbell GS, Allevato G, Billestrup N, et al. Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase. J Biol Chem 1994;269:21709-17.
    • (1994) J Biol Chem , vol.269 , pp. 21709-21717
    • VanderKuur, J.A.1    Wang, X.2    Zhang, L.3    Campbell, G.S.4    Allevato, G.5    Billestrup, N.6
  • 7
    • 0029024882 scopus 로고
    • Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor
    • Frank SJ, Yi W, Zhao Y, Goldsmith JF, Gilliland G, Jiang J, et al. Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor. J Biol Chem 1995;270:14776-85.
    • (1995) J Biol Chem , vol.270 , pp. 14776-14785
    • Frank, S.J.1    Yi, W.2    Zhao, Y.3    Goldsmith, J.F.4    Gilliland, G.5    Jiang, J.6
  • 8
    • 0028957771 scopus 로고
    • The conserved box 1 motif of cytokine receptors is required for association with JAK kinases
    • Tanner JW, Chen W, Young RL, Longmore GD, Shaw AS. The conserved box 1 motif of cytokine receptors is required for association with JAK kinases. J Biol Chem 1995;270:6523-30.
    • (1995) J Biol Chem , vol.270 , pp. 6523-6530
    • Tanner, J.W.1    Chen, W.2    Young, R.L.3    Longmore, G.D.4    Shaw, A.S.5
  • 11
    • 17544369037 scopus 로고    scopus 로고
    • Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation
    • Hansen LH, Wang X, Kopchick JJ, Bouchelouche P, Nielsen JH, Galsgaard ED, Billestrup N. Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation. J Biol Chem 1996;271:12669-73.
    • (1996) J Biol Chem , vol.271 , pp. 12669-12673
    • Hansen, L.H.1    Wang, X.2    Kopchick, J.J.3    Bouchelouche, P.4    Nielsen, J.H.5    Galsgaard, E.D.6    Billestrup, N.7
  • 12
    • 0030953469 scopus 로고    scopus 로고
    • Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop
    • Feng J, Witthuhn BA, Matsuda T, Kohlhuber F, Kerr IM, Ihle JN. Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop. Mol Cell Biol 1997;17:2497-501.
    • (1997) Mol Cell Biol , vol.17 , pp. 2497-2501
    • Feng, J.1    Witthuhn, B.A.2    Matsuda, T.3    Kohlhuber, F.4    Kerr, I.M.5    Ihle, J.N.6
  • 13
  • 14
    • 33750221616 scopus 로고    scopus 로고
    • Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2
    • Funakoshi-Tago M, Pelletier S, Matsuda T, Parganas E, Ihle JN. Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2. Embo J 2006;25:4763-72.
    • (2006) Embo J , vol.25 , pp. 4763-4772
    • Funakoshi-Tago, M.1    Pelletier, S.2    Matsuda, T.3    Parganas, E.4    Ihle, J.N.5
  • 15
    • 20244389693 scopus 로고    scopus 로고
    • The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop
    • Yasukawa H, Misawa H, Sakamoto H, Masuhara M, Sasaki A, Wakioka T, et al. The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop. Embo J 1999;18:1309-20.
    • (1999) Embo J , vol.18 , pp. 1309-1320
    • Yasukawa, H.1    Misawa, H.2    Sakamoto, H.3    Masuhara, M.4    Sasaki, A.5    Wakioka, T.6
  • 16
    • 0032803530 scopus 로고    scopus 로고
    • Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain
    • Sasaki A, Yasukawa H, Suzuki A, Kamizono S, Syoda T, Kinjyo I, Sasaki M, Johnston JA, Yoshimura A. Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain. Genes Cells 1999;4:339-51.
    • (1999) Genes Cells , vol.4 , pp. 339-351
    • Sasaki, A.1    Yasukawa, H.2    Suzuki, A.3    Kamizono, S.4    Syoda, T.5    Kinjyo, I.6    Sasaki, M.7    Johnston, J.A.8    Yoshimura, A.9
  • 18
    • 33747748126 scopus 로고    scopus 로고
    • Binding of SH2-B family members within a potential negative regulatory region maintains JAK2 in an active state
    • Kurzer JH, Saharinen P, Silvennoinen O, Carter-Su C. Binding of SH2-B family members within a potential negative regulatory region maintains JAK2 in an active state. Mol Cell Biol 2006;26:6381-94.
    • (2006) Mol Cell Biol , vol.26 , pp. 6381-6394
    • Kurzer, J.H.1    Saharinen, P.2    Silvennoinen, O.3    Carter-Su, C.4
  • 20
    • 0036837657 scopus 로고    scopus 로고
    • Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein
    • Carpino N, Kobayashi R, Zang H, Takahashi Y, Jou ST, Feng J, Nakajima H, Ihle JN. Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein. Mol Cell Biol 2002;22:7491-500.
    • (2002) Mol Cell Biol , vol.22 , pp. 7491-7500
    • Carpino, N.1    Kobayashi, R.2    Zang, H.3    Takahashi, Y.4    Jou, S.T.5    Feng, J.6    Nakajima, H.7    Ihle, J.N.8
  • 21
    • 0000963436 scopus 로고    scopus 로고
    • Molecular events in growth hormone-receptor interaction and signaling
    • Kostyo JL, editor, New York: Oxford University Press;
    • Smit LS, Meyer DJ, Argetsinger LS, Schwartz J, Carter-Su C. Molecular events in growth hormone-receptor interaction and signaling. In: Kostyo JL, editor. Handbook of physiology. New York: Oxford University Press; 1999. p. 445-80.
    • (1999) Handbook of physiology , pp. 445-480
    • Smit, L.S.1    Meyer, D.J.2    Argetsinger, L.S.3    Schwartz, J.4    Carter-Su, C.5
  • 22
    • 0029968831 scopus 로고
    • The role of the growth hormone receptor and JAK1 and JAK2 kinases in the activation of Stats 1 and 3 by growth hormone
    • Smit LS, Meyer DJ, Billestrup N, Norstedt G, Schwartz J, Carter-Su C. The role of the growth hormone receptor and JAK1 and JAK2 kinases in the activation of Stats 1 and 3 by growth hormone. Mol Endocrinol 1995;10:519-33.
    • (1995) Mol Endocrinol , vol.10 , pp. 519-533
    • Smit, L.S.1    Meyer, D.J.2    Billestrup, N.3    Norstedt, G.4    Schwartz, J.5    Carter-Su, C.6
  • 23
    • 0029760144 scopus 로고    scopus 로고
    • Identification of growth hormone receptor (GHR) tyrosine residues required for GHR phosphorylation and JAK2 and STAT5 activation
    • Wang X, Darus CJ, Xu BC, Kopchick JJ. Identification of growth hormone receptor (GHR) tyrosine residues required for GHR phosphorylation and JAK2 and STAT5 activation. Mol Endocrinol 1996;10:1249-60.
    • (1996) Mol Endocrinol , vol.10 , pp. 1249-1260
    • Wang, X.1    Darus, C.J.2    Xu, B.C.3    Kopchick, J.J.4
  • 24
    • 0030737957 scopus 로고    scopus 로고
    • Growth hormone-induced tyrosyl phosphorylation and DNA binding activity of Stat5A and Stat5B
    • Smit LS, VanderKuur JA, Stimage A, Han Y, Luo G, Yu-lee L, et al. Growth hormone-induced tyrosyl phosphorylation and DNA binding activity of Stat5A and Stat5B. Endocrinol 1997;138:3426-34.
    • (1997) Endocrinol , vol.138 , pp. 3426-3434
    • Smit, L.S.1    VanderKuur, J.A.2    Stimage, A.3    Han, Y.4    Luo, G.5    Yu-lee, L.6
  • 26
    • 0037160137 scopus 로고    scopus 로고
    • Identification of a JAK2-independent pathway regulating growth hormone (GH)-stimulated p44/42 mitogen-activated protein kinase activity. GH activation of Ral and phospholipase D is Src-dependent
    • Zhu T, Ling L, Lobie PE. Identification of a JAK2-independent pathway regulating growth hormone (GH)-stimulated p44/42 mitogen-activated protein kinase activity. GH activation of Ral and phospholipase D is Src-dependent. J Biol Chem 2002;277:45592-603.
    • (2002) J Biol Chem , vol.277 , pp. 45592-45603
    • Zhu, T.1    Ling, L.2    Lobie, P.E.3
  • 27
    • 0038034941 scopus 로고    scopus 로고
    • Src-CrkII-C3G-dependent activation of Rap1 switches growth hormone-stimulated p44/42 MAP kinase and JNK/SAPK activities
    • Ling L, Zhu T, Lobie PE. Src-CrkII-C3G-dependent activation of Rap1 switches growth hormone-stimulated p44/42 MAP kinase and JNK/SAPK activities. J Biol Chem 2003;278:27301-11.
    • (2003) J Biol Chem , vol.278 , pp. 27301-27311
    • Ling, L.1    Zhu, T.2    Lobie, P.E.3
  • 28
    • 33748103173 scopus 로고    scopus 로고
    • Src transduces signaling via growth hormone (GH)-activated GH receptor (GHR) tyrosine-phosphorylating GHR and STAT5 in human leukemia cells
    • Manabe N, Kubota Y, Kitanaka A, Ohnishi H, Taminato T, Tanaka T. Src transduces signaling via growth hormone (GH)-activated GH receptor (GHR) tyrosine-phosphorylating GHR and STAT5 in human leukemia cells. Leuk Res 2006;30:1391-8.
    • (2006) Leuk Res , vol.30 , pp. 1391-1398
    • Manabe, N.1    Kubota, Y.2    Kitanaka, A.3    Ohnishi, H.4    Taminato, T.5    Tanaka, T.6
  • 29
    • 33748423394 scopus 로고    scopus 로고
    • Involvement of JAK2 and Src kinase tyrosine phosphorylation in human growth hormone-stimulated increases in cytosolic free Ca2+ and insulin secretion
    • Zhang F, Zhang Q, Tengholm A, Sjoholm A. Involvement of JAK2 and Src kinase tyrosine phosphorylation in human growth hormone-stimulated increases in cytosolic free Ca2+ and insulin secretion. Am J Physiol Cell Physiol 2006;291:C466-75.
    • (2006) Am J Physiol Cell Physiol , vol.291
    • Zhang, F.1    Zhang, Q.2    Tengholm, A.3    Sjoholm, A.4
  • 32
    • 33947170405 scopus 로고    scopus 로고
    • Pravin B, Sehgal, editors. Signal Transducers and Activators of Transcription STATs, Dordrecht, The Netherlands: Kluwer;
    • Kurzer. Growth hormone induced activation and regulation of Jak2 and Stat proteins. In: Pravin B, Sehgal DEL, Toshio Hirano, editors. Signal Transducers and Activators of Transcription (STATs). Dordrecht, The Netherlands: Kluwer; 2003. p. 177-90.
    • (2003) Growth hormone induced activation and regulation of Jak2 and Stat proteins , pp. 177-190
    • Kurzer1
  • 33
    • 33744456856 scopus 로고    scopus 로고
    • Growth hormone regulation of sex-dependent liver gene expression
    • Waxman DJ, O'Connor C. Growth hormone regulation of sex-dependent liver gene expression. Mol Endocrinol 2006;20:2613-29.
    • (2006) Mol Endocrinol , vol.20 , pp. 2613-2629
    • Waxman, D.J.1    O'Connor, C.2
  • 34
    • 0346435095 scopus 로고    scopus 로고
    • Mechanisms of growth hormone (GH) action. Identification of conserved Stat5 binding sites that mediate GH-induced insulin-like growth factor-I gene activation
    • Woelfle J, Chia DJ, Rotwein P. Mechanisms of growth hormone (GH) action. Identification of conserved Stat5 binding sites that mediate GH-induced insulin-like growth factor-I gene activation. J Biol Chem 2003;278:51261-6.
    • (2003) J Biol Chem , vol.278 , pp. 51261-51266
    • Woelfle, J.1    Chia, D.J.2    Rotwein, P.3
  • 35
    • 33645649507 scopus 로고    scopus 로고
    • Characterization of distinct Stat5b binding sites that mediate growth hormone-stimulated IGF-I gene transcription
    • Chia DJ, Ono M, Woelfle J, Schlesinger-Massart M, Jiang H, Rotwein P. Characterization of distinct Stat5b binding sites that mediate growth hormone-stimulated IGF-I gene transcription. J Biol Chem 2006;281:3190-7.
    • (2006) J Biol Chem , vol.281 , pp. 3190-3197
    • Chia, D.J.1    Ono, M.2    Woelfle, J.3    Schlesinger-Massart, M.4    Jiang, H.5    Rotwein, P.6
  • 37
    • 33750798269 scopus 로고    scopus 로고
    • Functional interaction of common {gamma}-chain and growth hormone receptor signaling apparatus
    • Adriani M, Garbi C, Amodio G, Russo I, Giovannini M, Amorosi S, et al. Functional interaction of common {gamma}-chain and growth hormone receptor signaling apparatus. J Immunol 2006;177:6889-95.
    • (2006) J Immunol , vol.177 , pp. 6889-6895
    • Adriani, M.1    Garbi, C.2    Amodio, G.3    Russo, I.4    Giovannini, M.5    Amorosi, S.6
  • 38
    • 33746131621 scopus 로고    scopus 로고
    • Growth hormone/JAK-STAT axis signal-transduction defect. A novel treatable cause of growth failure
    • Rojas-Gil AP, Ziros PG, Diaz L, Kletsas D, Basdra EK, Alexandrides TK, et al. Growth hormone/JAK-STAT axis signal-transduction defect. A novel treatable cause of growth failure. Febs J 2006;273:3454-66.
    • (2006) Febs J , vol.273 , pp. 3454-3466
    • Rojas-Gil, A.P.1    Ziros, P.G.2    Diaz, L.3    Kletsas, D.4    Basdra, E.K.5    Alexandrides, T.K.6
  • 39
    • 0026767414 scopus 로고
    • Growth hormone stimulates the tyrosyl phosphorylation of 42- and 45-kDa ERK-related proteins
    • Winston LA, Bertics PJ. Growth hormone stimulates the tyrosyl phosphorylation of 42- and 45-kDa ERK-related proteins. J Biol Chem 1992;267:4747-51.
    • (1992) J Biol Chem , vol.267 , pp. 4747-4751
    • Winston, L.A.1    Bertics, P.J.2
  • 40
    • 0028944585 scopus 로고
    • Growth hormone-promoted tyrosyl phosphorylation of Shc proteins and Shc association with Grb2
    • VanderKuur J, Allevato G, Billestrup N, Norstedt G, Carter-Su C. Growth hormone-promoted tyrosyl phosphorylation of Shc proteins and Shc association with Grb2. J Biol Chem 1995;270:7587-93.
    • (1995) J Biol Chem , vol.270 , pp. 7587-7593
    • VanderKuur, J.1    Allevato, G.2    Billestrup, N.3    Norstedt, G.4    Carter-Su, C.5
  • 41
    • 0029620504 scopus 로고
    • JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone
    • Winston LA, Hunter T. JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone. J Biol Chem 1995;270:30837-40.
    • (1995) J Biol Chem , vol.270 , pp. 30837-30840
    • Winston, L.A.1    Hunter, T.2
  • 43
    • 0030656447 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone
    • Yamauchi T, Ueki K, Tobe K, Tamemoto H, Sekine N, Wada M, et al. Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone. Nature 1997;390:91-6.
    • (1997) Nature , vol.390 , pp. 91-96
    • Yamauchi, T.1    Ueki, K.2    Tobe, K.3    Tamemoto, H.4    Sekine, N.5    Wada, M.6
  • 44
    • 0037113978 scopus 로고    scopus 로고
    • Dual regulation of phosphorylation and dephosphorylation of C/EBPbeta modulate its transcriptional activation and DNA binding in response to growth hormone
    • Piwien-Pilipuk G, MacDougald O, Schwartz J. Dual regulation of phosphorylation and dephosphorylation of C/EBPbeta modulate its transcriptional activation and DNA binding in response to growth hormone. J Biol Chem 2002;277:44557-65.
    • (2002) J Biol Chem , vol.277 , pp. 44557-44565
    • Piwien-Pilipuk, G.1    MacDougald, O.2    Schwartz, J.3
  • 45
    • 0042316837 scopus 로고    scopus 로고
    • Subnuclear localization of C/EBP beta is regulated by growth hormone and dependent on MAPK
    • Piwien Pilipuk G, Galigniana MD, Schwartz J. Subnuclear localization of C/EBP beta is regulated by growth hormone and dependent on MAPK. J Biol Chem 2003;278:35668-77
    • (2003) J Biol Chem , vol.278 , pp. 35668-35677
    • Piwien Pilipuk, G.1    Galigniana, M.D.2    Schwartz, J.3
  • 46
    • 0032515065 scopus 로고    scopus 로고
    • The role of C/EBP genes in adipocyte differentiation
    • Darlington GJ, Ross SE, MacDougald OA. The role of C/EBP genes in adipocyte differentiation. J Biol Chem 1998;273:30057-60.
    • (1998) J Biol Chem , vol.273 , pp. 30057-30060
    • Darlington, G.J.1    Ross, S.E.2    MacDougald, O.A.3
  • 47
    • 14944365624 scopus 로고    scopus 로고
    • Inadequacy of the Janus kinase 2/signal transducer and activator of transcription signal transduction pathway to mediate episodic growth hormone-dependent regulation of hepatic CYP2C11
    • Verma AS, Dhir RN, Shapiro BH. Inadequacy of the Janus kinase 2/signal transducer and activator of transcription signal transduction pathway to mediate episodic growth hormone-dependent regulation of hepatic CYP2C11. Mol Pharmacol 2005;67:891-901.
    • (2005) Mol Pharmacol , vol.67 , pp. 891-901
    • Verma, A.S.1    Dhir, R.N.2    Shapiro, B.H.3
  • 48
    • 2442675157 scopus 로고    scopus 로고
    • Caveolar and lipid raft localization of the growth hormone receptor and its signaling elements: Impact on growth hormone signaling
    • Yang N, Huang Y, Jiang J, Frank SJ. Caveolar and lipid raft localization of the growth hormone receptor and its signaling elements: impact on growth hormone signaling. J Biol Chem 2004;279:20898-905.
    • (2004) J Biol Chem , vol.279 , pp. 20898-20905
    • Yang, N.1    Huang, Y.2    Jiang, J.3    Frank, S.J.4
  • 49
    • 0034625343 scopus 로고    scopus 로고
    • CrkII participation in the cellular effects of growth hormone and insulin-like growth factor-1. Phosphatidylinositol-3 kinase dependent and independent effects
    • Goh EL, Zhu T, Yakar S, LeRoith D, Lobie PE. CrkII participation in the cellular effects of growth hormone and insulin-like growth factor-1. Phosphatidylinositol-3 kinase dependent and independent effects. J Biol Chem 2000;275:17683-92.
    • (2000) J Biol Chem , vol.275 , pp. 17683-17692
    • Goh, E.L.1    Zhu, T.2    Yakar, S.3    LeRoith, D.4    Lobie, P.E.5
  • 50
    • 0032568922 scopus 로고    scopus 로고
    • Grb10 identified as a potential regulator of growth hormone (GH) signaling by cloning of GH receptor target proteins
    • Moutoussamy S, Renaudie F, Lago F, Kelly PA, Finidori J. Grb10 identified as a potential regulator of growth hormone (GH) signaling by cloning of GH receptor target proteins. J Biol Chem 1998;273:15906-12.
    • (1998) J Biol Chem , vol.273 , pp. 15906-15912
    • Moutoussamy, S.1    Renaudie, F.2    Lago, F.3    Kelly, P.A.4    Finidori, J.5
  • 51
    • 0032537942 scopus 로고    scopus 로고
    • Effect of growth hormone on the translocation of GLUT4 and its relation to insulin-like and anti-insulin action
    • Yokota I, Hayashi H, Matsuda J, Saijo T, Naito E, Ito M, et al. Effect of growth hormone on the translocation of GLUT4 and its relation to insulin-like and anti-insulin action. Biochim Biophys Acta 1998;1404:451-6.
    • (1998) Biochim Biophys Acta , vol.1404 , pp. 451-456
    • Yokota, I.1    Hayashi, H.2    Matsuda, J.3    Saijo, T.4    Naito, E.5    Ito, M.6
  • 52
    • 0033305495 scopus 로고    scopus 로고
    • Activation of growth hormone receptor delivers an antiapoptotic signal: Evidence for a role of Akt in this pathway
    • Costoya JA, Finidori J, Moutoussamy S, Searis R, Devesa J, Arce VM. Activation of growth hormone receptor delivers an antiapoptotic signal: evidence for a role of Akt in this pathway. Endocrinol 1999;140:5937-43.
    • (1999) Endocrinol , vol.140 , pp. 5937-5943
    • Costoya, J.A.1    Finidori, J.2    Moutoussamy, S.3    Searis, R.4    Devesa, J.5    Arce, V.M.6
  • 53
    • 33748714325 scopus 로고    scopus 로고
    • Retinal ganglion cell survival in development: Mechanisms of retinal growth hormone action
    • Sanders EJ, Parker E, Harvey S. Retinal ganglion cell survival in development: mechanisms of retinal growth hormone action. Exp Eye Res 2006;83:1205-14.
    • (2006) Exp Eye Res , vol.83 , pp. 1205-1214
    • Sanders, E.J.1    Parker, E.2    Harvey, S.3
  • 54
    • 0029872617 scopus 로고    scopus 로고
    • Requirement for phosphoinositide 3-OH kinase in growth hormone signalling to the mitogen-activated protein kinase and p70s6k pathways
    • Kilgour E, Gout I, Anderson NG. Requirement for phosphoinositide 3-OH kinase in growth hormone signalling to the mitogen-activated protein kinase and p70s6k pathways. Biochem J 1996;315:517-22.
    • (1996) Biochem J , vol.315 , pp. 517-522
    • Kilgour, E.1    Gout, I.2    Anderson, N.G.3
  • 55
    • 0032584089 scopus 로고    scopus 로고
    • Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytes
    • MacKenzie SJ, Yarwood SJ, Peden AH, Bolger GB, Vernon RG, Houslay MD. Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytes. Proc Natl Acad Sci USA 1998;95:3549-54.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3549-3554
    • MacKenzie, S.J.1    Yarwood, S.J.2    Peden, A.H.3    Bolger, G.B.4    Vernon, R.G.5    Houslay, M.D.6
  • 56
    • 0027336392 scopus 로고
    • Simultaneous activation of p90RSK and p70S6K S6 kinases by growth hormone in 3T3-F442A preadipocytes
    • Anderson NG. Simultaneous activation of p90RSK and p70S6K S6 kinases by growth hormone in 3T3-F442A preadipocytes. Biochem Biophys Res Commun 1993;193:284-90.
    • (1993) Biochem Biophys Res Commun , vol.193 , pp. 284-290
    • Anderson, N.G.1
  • 57
    • 0030795552 scopus 로고    scopus 로고
    • Growth hormone-induced reorganization of the actin cytoskeleton is not required for STAT5 (signal transducer and activator of transcription-5)-mediated transcription
    • Goh EL, Pircher TJ, Wood TJ, Norstedt G, Graichen R, Lobie PE. Growth hormone-induced reorganization of the actin cytoskeleton is not required for STAT5 (signal transducer and activator of transcription-5)-mediated transcription. Endocrinol 1997;138:3207-15.
    • (1997) Endocrinol , vol.138 , pp. 3207-3215
    • Goh, E.L.1    Pircher, T.J.2    Wood, T.J.3    Norstedt, G.4    Graichen, R.5    Lobie, P.E.6
  • 58
    • 0031734567 scopus 로고    scopus 로고
    • Growth hormone promotion of tubulin polymerization stabilizes the microtubule network and protects against colchicine-induced apoptosis
    • Goh EL, Pircher TJ, Lobie PE. Growth hormone promotion of tubulin polymerization stabilizes the microtubule network and protects against colchicine-induced apoptosis. Endocrinol 1998;139:4364-72.
    • (1998) Endocrinol , vol.139 , pp. 4364-4372
    • Goh, E.L.1    Pircher, T.J.2    Lobie, P.E.3
  • 59
    • 0032509512 scopus 로고    scopus 로고
    • Growth hormone stimulates the formation of a multiprotein signaling complex involving p130Cas and CrkII. Resultant activation of c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK)
    • Zhu T, Goh ELK, LeRoith D, Lobie PE. Growth hormone stimulates the formation of a multiprotein signaling complex involving p130Cas and CrkII. Resultant activation of c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK). J Biol Chem 1998;273:33864-75.
    • (1998) J Biol Chem , vol.273 , pp. 33864-33875
    • Zhu, T.1    Goh, E.L.K.2    LeRoith, D.3    Lobie, P.E.4
  • 60
    • 0032559562 scopus 로고    scopus 로고
    • Klemke RL, Leng J, Molander R, Brooks PC, Vuori K, Cheresh DA. CAS/Crk coupling serves as a molecular switch for induction of cell migration. J Cell Biol 1998;140:961-72.
    • Klemke RL, Leng J, Molander R, Brooks PC, Vuori K, Cheresh DA. CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. J Cell Biol 1998;140:961-72.
  • 61
    • 0032562717 scopus 로고    scopus 로고
    • Growth hormone stimulates the tyrosine phosphorylation and association of p125 focal adhesion kinase (FAK) with JAK2. Fak is not required for stat-mediated transcription
    • Zhu T, Goh EL, Lobie PE. Growth hormone stimulates the tyrosine phosphorylation and association of p125 focal adhesion kinase (FAK) with JAK2. Fak is not required for stat-mediated transcription. J Biol Chem 1998;273:10682-89.
    • (1998) J Biol Chem , vol.273 , pp. 10682-10689
    • Zhu, T.1    Goh, E.L.2    Lobie, P.E.3
  • 62
    • 0034695690 scopus 로고    scopus 로고
    • Janus kinase 2-dependent activation of p38 mitogen-activated protein kinase by growth hormone. Resultant transcriptional activation of ATF-2 and CHOP, cytoskeletal reorganization and mitogenesis
    • Zhu T, Lobie PE. Janus kinase 2-dependent activation of p38 mitogen-activated protein kinase by growth hormone. Resultant transcriptional activation of ATF-2 and CHOP, cytoskeletal reorganization and mitogenesis. J Biol Chem 2000;275:2103-14.
    • (2000) J Biol Chem , vol.275 , pp. 2103-2114
    • Zhu, T.1    Lobie, P.E.2
  • 64
    • 0037155344 scopus 로고    scopus 로고
    • SH2-Bb is a Rac-binding protein that regulates cell motility
    • Diakonova M, Gunter DR, Herrington J, Carter-Su C. SH2-Bb is a Rac-binding protein that regulates cell motility. J Biol Chem 2002;277:10669-77.
    • (2002) J Biol Chem , vol.277 , pp. 10669-10677
    • Diakonova, M.1    Gunter, D.R.2    Herrington, J.3    Carter-Su, C.4
  • 66
    • 20244389693 scopus 로고    scopus 로고
    • The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop
    • Yasukawa H, Misawa H, Sakamoto H, Masuhara M, Sasaki A, Wakioka T, et al. The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop. Embo J 1999;18:1309-20.
    • (1999) Embo J , vol.18 , pp. 1309-1320
    • Yasukawa, H.1    Misawa, H.2    Sakamoto, H.3    Masuhara, M.4    Sasaki, A.5    Wakioka, T.6
  • 67
    • 0033305402 scopus 로고    scopus 로고
    • Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins
    • Hansen JA, Lindberg K, Hilton DJ, Nielsen JH, Billestrup N. Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins. Mol Endocrinol 1999;13:1832-43.
    • (1999) Mol Endocrinol , vol.13 , pp. 1832-1843
    • Hansen, J.A.1    Lindberg, K.2    Hilton, D.J.3    Nielsen, J.H.4    Billestrup, N.5
  • 68
    • 0033544899 scopus 로고    scopus 로고
    • Ram PA, Waxman DJ. SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms. J Biol Chem 1999;274:35553-61.
    • Ram PA, Waxman DJ. SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms. J Biol Chem 1999;274:35553-61.
  • 69
    • 0037174816 scopus 로고    scopus 로고
    • Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling
    • Greenhalgh CJ, Metcalf D, Thaus AL, Corbin JE, Uren R, Morgan PO, et al. Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling. J Biol Chem 2002;277:40181-4.
    • (2002) J Biol Chem , vol.277 , pp. 40181-40184
    • Greenhalgh, C.J.1    Metcalf, D.2    Thaus, A.L.3    Corbin, J.E.4    Uren, R.5    Morgan, P.O.6
  • 70
    • 27844472746 scopus 로고    scopus 로고
    • Role of the cytokine-induced SH2 domain-containing protein CIS in growth hormone receptor internalization
    • Landsman T, Waxman DJ. Role of the cytokine-induced SH2 domain-containing protein CIS in growth hormone receptor internalization. J Biol Chem 2005;280:37471-80.
    • (2005) J Biol Chem , vol.280 , pp. 37471-37480
    • Landsman, T.1    Waxman, D.J.2
  • 75
    • 0033520326 scopus 로고    scopus 로고
    • SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine
    • Alexander WS, Starr R, Fenner JE, Scott CL, Handman E, Sprigg NS, et al. SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine. Cell 1999;98:597-608.
    • (1999) Cell , vol.98 , pp. 597-608
    • Alexander, W.S.1    Starr, R.2    Fenner, J.E.3    Scott, C.L.4    Handman, E.5    Sprigg, N.S.6
  • 77
    • 17744382150 scopus 로고    scopus 로고
    • Differential expression of suppressors of cytokine signalling genes in response to nutrition and growth hormone in the septic rat
    • Johnson TS, O'Leary M, Justice SK, Maamra M, Zarkesh-Esfahani SH, Furlanetto R, et al. Differential expression of suppressors of cytokine signalling genes in response to nutrition and growth hormone in the septic rat. J Endocrinol 2001;169:409-15.
    • (2001) J Endocrinol , vol.169 , pp. 409-415
    • Johnson, T.S.1    O'Leary, M.2    Justice, S.K.3    Maamra, M.4    Zarkesh-Esfahani, S.H.5    Furlanetto, R.6
  • 78
    • 33646560290 scopus 로고    scopus 로고
    • Hepatic growth hormone resistance during sepsis is associated with increased suppressors of cytokine signaling expression and impaired growth hormone signaling
    • Yumet G, Shumate ML, Bryant DP, Lang CH, Cooney RN. Hepatic growth hormone resistance during sepsis is associated with increased suppressors of cytokine signaling expression and impaired growth hormone signaling. Crit Care Med 2006;34:1420-7.
    • (2006) Crit Care Med , vol.34 , pp. 1420-1427
    • Yumet, G.1    Shumate, M.L.2    Bryant, D.P.3    Lang, C.H.4    Cooney, R.N.5
  • 79
    • 0034908363 scopus 로고    scopus 로고
    • Impaired JAKSTAT signal transduction contributes to growth hormone resistance in chronic uremia
    • Schaefer F, Chen Y, Tsao T, Nouri P, Rabkin R. Impaired JAKSTAT signal transduction contributes to growth hormone resistance in chronic uremia. J Clin Invest 2001;108:467-75.
    • (2001) J Clin Invest , vol.108 , pp. 467-475
    • Schaefer, F.1    Chen, Y.2    Tsao, T.3    Nouri, P.4    Rabkin, R.5
  • 80
    • 0030945444 scopus 로고    scopus 로고
    • Mapping of a cytoplasmic domain of the human growth hormone receptor that regulates rates of inactivation of Jak2 and Stat proteins
    • Hackett RH, Wang YD, Sweitzer S, Feldman G, Wood WI, Larner AC. Mapping of a cytoplasmic domain of the human growth hormone receptor that regulates rates of inactivation of Jak2 and Stat proteins. J Biol Chem 1997;272:11128-32.
    • (1997) J Biol Chem , vol.272 , pp. 11128-11132
    • Hackett, R.H.1    Wang, Y.D.2    Sweitzer, S.3    Feldman, G.4    Wood, W.I.5    Larner, A.C.6
  • 81
    • 0031890381 scopus 로고    scopus 로고
    • Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling
    • Kim SO, Jiang J, Yi W, Feng GS, Frank SJ. Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling. J Biol Chem 1998;273:2344-54.
    • (1998) J Biol Chem , vol.273 , pp. 2344-2354
    • Kim, S.O.1    Jiang, J.2    Yi, W.3    Feng, G.S.4    Frank, S.J.5
  • 82
    • 0033755417 scopus 로고    scopus 로고
    • Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B
    • Stofega MR, Herrington J, Billestrup N, Carter-Su C. Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B. Mol Endo 2000;14:1338-50.
    • (2000) Mol Endo , vol.14 , pp. 1338-1350
    • Stofega, M.R.1    Herrington, J.2    Billestrup, N.3    Carter-Su, C.4
  • 83
    • 0034623242 scopus 로고    scopus 로고
    • Negative regulation of growth hormone receptor/JAK2 signaling by signal regulatory protein a
    • Stofega MR, Argetsinger LS, Wang H, Ullrich A, Carter-Su C. Negative regulation of growth hormone receptor/JAK2 signaling by signal regulatory protein a. J Biol Chem 2000;275:28222-9.
    • (2000) J Biol Chem , vol.275 , pp. 28222-28229
    • Stofega, M.R.1    Argetsinger, L.S.2    Wang, H.3    Ullrich, A.4    Carter-Su, C.5
  • 86
    • 33751536492 scopus 로고    scopus 로고
    • Phospholipase Cgamma1 negatively regulates growth hormone signalling by forming a ternary complex with Jak2 and protein tyrosine phosphatase-1B
    • Choi JH, Kim HS, Kim SH, Yang YR, Bae YS, Chang JS, et al. Phospholipase Cgamma1 negatively regulates growth hormone signalling by forming a ternary complex with Jak2 and protein tyrosine phosphatase-1B. Nat Cell Biol 2006;8:1389-97.
    • (2006) Nat Cell Biol , vol.8 , pp. 1389-1397
    • Choi, J.H.1    Kim, H.S.2    Kim, S.H.3    Yang, Y.R.4    Bae, Y.S.5    Chang, J.S.6
  • 87
    • 0033521670 scopus 로고    scopus 로고
    • Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor
    • Govers R, ten Broeke T, van Kerkhof P, Schwartz AL, Strous GJ. Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor. Embo J 1999;18:28-36.
    • (1999) Embo J , vol.18 , pp. 28-36
    • Govers, R.1    ten Broeke, T.2    van Kerkhof, P.3    Schwartz, A.L.4    Strous, G.J.5
  • 88
    • 0034695587 scopus 로고    scopus 로고
    • Endocytosis and degradation of the growth hormone receptor are proteasome-dependent
    • van Kerkhof P, Govers R, Alves dos Santos CM, Strous GJ. Endocytosis and degradation of the growth hormone receptor are proteasome-dependent. J Biol Chem 2000;275:1575-80.
    • (2000) J Biol Chem , vol.275 , pp. 1575-1580
    • van Kerkhof, P.1    Govers, R.2    Alves dos Santos, C.M.3    Strous, G.J.4
  • 89
    • 33744455446 scopus 로고    scopus 로고
    • Subcellular shift of the hepatic growth hormone receptor with progression of hepatitis C virus-related chronic liver disease
    • Vespasiani Gentilucci U, Perrone G, Galati G, D'Avola D, Zardi EM, Rabitti C, et al. Subcellular shift of the hepatic growth hormone receptor with progression of hepatitis C virus-related chronic liver disease. Histopathology 2006;48:822-30.
    • (2006) Histopathology , vol.48 , pp. 822-830
    • Vespasiani Gentilucci, U.1    Perrone, G.2    Galati, G.3    D'Avola, D.4    Zardi, E.M.5    Rabitti, C.6
  • 90
    • 1242339600 scopus 로고    scopus 로고
    • Downregulation of the growth hormone-induced Janus kinase 2/signal transducer and activator of transcription 5 signaling pathway requires an intact actin cytoskeleton
    • Rico-Bautista E, Negrin-Martinez C, Novoa-Mogollon J, Fernandez-Perez L, Flores-Morales A. Downregulation of the growth hormone-induced Janus kinase 2/signal transducer and activator of transcription 5 signaling pathway requires an intact actin cytoskeleton. Exp Cell Res 2004;294:269-80.
    • (2004) Exp Cell Res , vol.294 , pp. 269-280
    • Rico-Bautista, E.1    Negrin-Martinez, C.2    Novoa-Mogollon, J.3    Fernandez-Perez, L.4    Flores-Morales, A.5
  • 91
    • 4344624361 scopus 로고    scopus 로고
    • Got RIP? Presenilin-dependent intramembrane proteolysis in growth factor receptor signaling
    • Landman N, Kim TW. Got RIP? Presenilin-dependent intramembrane proteolysis in growth factor receptor signaling. Cytokine Growth Factor Rev 2004;15:337-51.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 337-351
    • Landman, N.1    Kim, T.W.2
  • 92
    • 0034520154 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha converting enzyme (TACE) is a growth hormone binding protein (GHBP) sheddase: The metalloprotease TACE/ADAM-17 is critical for (PMA-induced) GH receptor proteolysis and GHBP generation
    • Zhang Y, Jiang J, Black RA, Baumann G, Frank SJ. Tumor necrosis factor-alpha converting enzyme (TACE) is a growth hormone binding protein (GHBP) sheddase: the metalloprotease TACE/ADAM-17 is critical for (PMA-induced) GH receptor proteolysis and GHBP generation. Endocrinol 2000;141:4342-8.
    • (2000) Endocrinol , vol.141 , pp. 4342-4348
    • Zhang, Y.1    Jiang, J.2    Black, R.A.3    Baumann, G.4    Frank, S.J.5
  • 93
    • 21444457762 scopus 로고    scopus 로고
    • Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage
    • Cowan JW, Wang X, Guan R, He K, Jiang J, Baumann G, et al. Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage. J Biol Chem 2005;280:19331-42.
    • (2005) J Biol Chem , vol.280 , pp. 19331-19342
    • Cowan, J.W.1    Wang, X.2    Guan, R.3    He, K.4    Jiang, J.5    Baumann, G.6
  • 94
    • 33751328082 scopus 로고    scopus 로고
    • ErbB receptors: New insights on mechanisms and biology
    • Linggi B, Carpenter G. ErbB receptors: new insights on mechanisms and biology. Trends Cell Biol 2006;16:649-56.
    • (2006) Trends Cell Biol , vol.16 , pp. 649-656
    • Linggi, B.1    Carpenter, G.2
  • 96
    • 0035992641 scopus 로고    scopus 로고
    • Localization and regulation of the growth hormone receptor and growth hormone-binding protein in the rat growth plate
    • Gevers EF, van der Eerden BC, Karperien M, Raap AK, Robinson IC, Wit JM. Localization and regulation of the growth hormone receptor and growth hormone-binding protein in the rat growth plate. J Bone Miner Res 2002;17:1408-19.
    • (2002) J Bone Miner Res , vol.17 , pp. 1408-1419
    • Gevers, E.F.1    van der Eerden, B.C.2    Karperien, M.3    Raap, A.K.4    Robinson, I.C.5    Wit, J.M.6
  • 98
    • 0030070235 scopus 로고    scopus 로고
    • Cellular trafficking of exogenous growth hormone in dwarf rat pituitary
    • Mertani HC, Waters MJ, Morel G. Cellular trafficking of exogenous growth hormone in dwarf rat pituitary. Neuroendocrinology 1996;63:257-68.
    • (1996) Neuroendocrinology , vol.63 , pp. 257-268
    • Mertani, H.C.1    Waters, M.J.2    Morel, G.3
  • 99
    • 29144462020 scopus 로고    scopus 로고
    • Growth hormone activity in mitochondria depends on GH receptor Box 1 and involves caveolar pathway targeting
    • Perret-Vivancos C, Abbate A, Ardail D, Raccurt M, Usson Y, Lobie PE, Morel G. Growth hormone activity in mitochondria depends on GH receptor Box 1 and involves caveolar pathway targeting. Exp Cell Res 2006;312:215-32.
    • (2006) Exp Cell Res , vol.312 , pp. 215-232
    • Perret-Vivancos, C.1    Abbate, A.2    Ardail, D.3    Raccurt, M.4    Usson, Y.5    Lobie, P.E.6    Morel, G.7


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