Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 26, 2003, Pages 15924-15929

  Tanaka, Toshiya ^a,b   Yamamoto, Joji ^c,d   Iwasaki, Satoshi ^d   Asaba, Hiroshi ^a   Hamura, Hiroki ^b   Ikeda, Yukio ^d   Watanabe, Mitsuhiro ^e   Magoori, Kenta ^a   Ioka, Ryoichi X ^d   Tachibana, Keisuke ^f   Watanabe, Yuichiro ^a   Uchiyama, Yasutoshi ^a   Sumi, Koichi ^a   Iguchi, Haruhisa ^d   Ito, Sadayoshi ^c   Doi, Takefumi ^f   Hamakubo, Takao ^a   Naito, Makoto ^g   Auwerx, Johan ^e   Yanagisawa, Masashi ^d,h   Kodama, Tatsuhiko ^a   Sakai, Juro ^a,d   more..

^a UNIVERSITY OF TOKYO   (Japan)

^b Grelan Pharmaceutical Co Ltd   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^f OSAKA UNIVERSITY   (Japan)

^g NIIGATA UNIVERSITY   (Japan)

^h HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Insulin resistance; Obesity; Pancreatic cell; PGC 1 ; Thermogenesis

Indexed keywords

[2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; FAT DROPLET; FATTY ACID; GLUCOSE; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIABETES MELLITUS; DIETARY INTAKE; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; GENE CONTROL; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LIPID DIET; MALE; METABOLIC DISORDER; METABOLISM; MITOCHONDRIAL RESPIRATION; MOUSE; MYOTUBE; NONHUMAN; OBESITY; PRIORITY JOURNAL; SKELETAL MUSCLE;

ANIMALS; DIMETHYL SULFOXIDE; ENZYMES; FATTY ACIDS, NONESTERIFIED; INSULIN RESISTANCE; LIPID METABOLISM; LIVER; MALE; METABOLIC SYNDROME X; MICE; MICE, INBRED C57BL; MICE, OBESE; MUSCLE, SKELETAL; OXIDATION-REDUCTION; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; THIAZOLES; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 9144271149     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0306981100     Document Type: Article

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