-
2
-
-
43949122957
-
Mice as clinically relevant models for the study of cytochrome P450-dependent metabolism
-
Muruganandan, S.; Sinal, C.J. Mice as clinically relevant models for the study of cytochrome P450-dependent metabolism. Clin. Pharmacol. Ther., 2008, 83(6), 818-828.
-
(2008)
Clin. Pharmacol. Ther
, vol.83
, Issue.6
, pp. 818-828
-
-
Muruganandan, S.1
Sinal, C.J.2
-
5
-
-
0002481616
-
Cytochrome P450 enzymes as biomarkers of PCB exposure and modulators of toxicity
-
Robertson, L.W, Hansen, L.G, Eds, University Press of Kentucky: Lexington
-
Bandiera, S.M. Cytochrome P450 enzymes as biomarkers of PCB exposure and modulators of toxicity. In PCBs: Recent Advances in Environmental Toxicology and Health Effects; Robertson, L.W., Hansen, L.G., Eds.; University Press of Kentucky: Lexington, 2001, pp. 185-192.
-
(2001)
PCBs: Recent Advances in Environmental Toxicology and Health Effects
, pp. 185-192
-
-
Bandiera, S.M.1
-
6
-
-
84892246340
-
Human cytochrome P450 enzymes
-
3rd ed, Ortiz de Montellano, P.R, Ed, Kluwer Academic/Plenum Publishers: New York
-
Guengerich, F.P. Human cytochrome P450 enzymes. In Cytochrome P450: Structure, Mechanism, and Biochemistry, 3rd ed.; Ortiz de Montellano, P.R., Ed.; Kluwer Academic/Plenum Publishers: New York, 2005, pp. 377-530.
-
(2005)
Cytochrome P450: Structure, Mechanism, and Biochemistry
, pp. 377-530
-
-
Guengerich, F.P.1
-
7
-
-
84899710005
-
Cytochrome P450 enzymes
-
Gad, S.C, Ed, John Wiley & Sons, Inc, Hoboken
-
Hrycay, E.G.; Bandiera, S.M. Cytochrome P450 enzymes. In Preclinical Development Handbook: ADME and Biopharmaceutical Properties; Gad, S.C., Ed.; John Wiley & Sons, Inc.: Hoboken, 2008, pp. 627-696.
-
(2008)
Preclinical Development Handbook: ADME and Biopharmaceutical Properties
, pp. 627-696
-
-
Hrycay, E.G.1
Bandiera, S.M.2
-
8
-
-
0842312531
-
Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants
-
Nelson, D.R.; Zeldin, D.C.; Hoffman, S.M.G.; Maltais, L.J.; Wain, H.M.; Nebert, D.W. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. Pharmacogenetics, 2004, 14(1), 1-18.
-
(2004)
Pharmacogenetics
, vol.14
, Issue.1
, pp. 1-18
-
-
Nelson, D.R.1
Zeldin, D.C.2
Hoffman, S.M.G.3
Maltais, L.J.4
Wain, H.M.5
Nebert, D.W.6
-
9
-
-
46449138900
-
Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening
-
McLaughlin, L.A.; Dickmann, L.J.; Wolf, C.R.; Henderson, C.J. Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening. Drug Metab. Dispos., 2008, 36(7), 1322-1331.
-
(2008)
Drug Metab. Dispos
, vol.36
, Issue.7
, pp. 1322-1331
-
-
McLaughlin, L.A.1
Dickmann, L.J.2
Wolf, C.R.3
Henderson, C.J.4
-
10
-
-
33646383620
-
4 ω-1/ω-2 hydroxylase in mouse polymorphonuclear leukocytes: Identification as the functional orthologue of human polymorphonuclear leukocyte CYP4F3A in the down-regulation of responses to LTB4
-
4 ω-1/ω-2 hydroxylase in mouse polymorphonuclear leukocytes: identification as the functional orthologue of human polymorphonuclear leukocyte CYP4F3A in the down-regulation of responses to LTB4. J. Biol. Chem., 2006, 281(11), 7189-7196.
-
(2006)
J. Biol. Chem
, vol.281
, Issue.11
, pp. 7189-7196
-
-
Christmas, P.1
Tolentino, K.2
Primo, V.3
Berry, K.Z.4
Murphy, R.C.5
Chen, M.6
Lee, D.M.7
Soberman, R.J.8
-
11
-
-
0033514998
-
Cytochrome P450 CYP1B1 determines susceptibility to 7,12-dimethylbenz[a]anthracene- induced lymphomas
-
Buters, J.T.M.; Sakai, S.; Richter, T.; Pineau, T.; Alexander, D.L.; Savas, U.; Doehmer, J.; Ward, J.M.; Jefcoate, C.R.; Gonzalez, F.J. Cytochrome P450 CYP1B1 determines susceptibility to 7,12-dimethylbenz[a]anthracene- induced lymphomas. Proc. Natl. Acad. Sci. USA, 1999, 96(5), 1977-1982.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, Issue.5
, pp. 1977-1982
-
-
Buters, J.T.M.1
Sakai, S.2
Richter, T.3
Pineau, T.4
Alexander, D.L.5
Savas, U.6
Doehmer, J.7
Ward, J.M.8
Jefcoate, C.R.9
Gonzalez, F.J.10
-
12
-
-
0033566691
-
-
Diliberto, J.J.; Burgin, D.E.; Birnbaum, L.S. Effects of CYP1A2 on disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,4,7,8- pentachlorodibenzofuran, and 2,2',4,4',5,5'-hexachlorobiphenyl in CYP1A2 knockout and parental (C57BL/6N and 129/Sv) strains of mice. Toxicol. Appl. Pharmacol., 1999, 159(1), 52-64.
-
Diliberto, J.J.; Burgin, D.E.; Birnbaum, L.S. Effects of CYP1A2 on disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,4,7,8- pentachlorodibenzofuran, and 2,2',4,4',5,5'-hexachlorobiphenyl in CYP1A2 knockout and parental (C57BL/6N and 129/Sv) strains of mice. Toxicol. Appl. Pharmacol., 1999, 159(1), 52-64.
-
-
-
-
13
-
-
0034614595
-
Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery
-
Dalton, T.P.; Dieter, M.Z.; Matlib, R.S.; Childs, N.L.; Shertzer, H.G.; Genter, M.B.; Nebert, D.W. Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery. Biochem. Biophys. Res. Commun., 2000, 267(1), 184-189.
-
(2000)
Biochem. Biophys. Res. Commun
, vol.267
, Issue.1
, pp. 184-189
-
-
Dalton, T.P.1
Dieter, M.Z.2
Matlib, R.S.3
Childs, N.L.4
Shertzer, H.G.5
Genter, M.B.6
Nebert, D.W.7
-
14
-
-
2142695286
-
Oral exposure to benzo[a]pyrene in the mouse: Detoxication by inducible cytochrome P450 is more important than metabolic activation
-
Uno, S.; Dalton, T.P.; Derkenne, S.; Curran, C.P.; Miller, M.L.; Shertzer, H.G.; Nebert, D.W. Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation. Mol. Pharmacol., 2004, 65(5), 1225-1237.
-
(2004)
Mol. Pharmacol
, vol.65
, Issue.5
, pp. 1225-1237
-
-
Uno, S.1
Dalton, T.P.2
Derkenne, S.3
Curran, C.P.4
Miller, M.L.5
Shertzer, H.G.6
Nebert, D.W.7
-
15
-
-
38649117595
-
Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract
-
Uno, S.; Dragin, N.; Miller, M.L.; Dalton, T.P.; Gonzalez, F.J.; Nebert, D.W. Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract. Free Radic. Biol. Med., 2008, 44(4), 570-583.
-
(2008)
Free Radic. Biol. Med
, vol.44
, Issue.4
, pp. 570-583
-
-
Uno, S.1
Dragin, N.2
Miller, M.L.3
Dalton, T.P.4
Gonzalez, F.J.5
Nebert, D.W.6
-
16
-
-
44249097769
-
Phenotype of the Cyp1a1/1a2/1b1(-/-) triple-knockout mouse
-
Dragin, N.; Shi, Z.; Madan, R.; Karp, C.L.; Sartor, M.A.; Chen, C.; Gonzalez, F.J.; Nebert, D.W. Phenotype of the Cyp1a1/1a2/1b1(-/-) triple-knockout mouse. Mol. Pharmacol., 2008, 73(6), 1844-1856.
-
(2008)
Mol. Pharmacol
, vol.73
, Issue.6
, pp. 1844-1856
-
-
Dragin, N.1
Shi, Z.2
Madan, R.3
Karp, C.L.4
Sartor, M.A.5
Chen, C.6
Gonzalez, F.J.7
Nebert, D.W.8
-
17
-
-
15844419997
-
Role of CYP2E1 in the hepatotoxicity of acetaminophen
-
Lee, S.S.T.; Buters, J.T.M.; Pineau, T.; Fernandez-Salguero, P.; Gonzalez, F.J. Role of CYP2E1 in the hepatotoxicity of acetaminophen. J. Biol. Chem., 1996, 271(20), 12063-12067.
-
(1996)
J. Biol. Chem
, vol.271
, Issue.20
, pp. 12063-12067
-
-
Lee, S.S.T.1
Buters, J.T.M.2
Pineau, T.3
Fernandez-Salguero, P.4
Gonzalez, F.J.5
-
18
-
-
34250785095
-
Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: Comparison of wild-type and Cyp2e1 (-/-) mice
-
Wolf, K.K.; Wood, S.G.; Allard, J.L.; Hunt, J.A.; Gorman, N.; Walton-Strong, B.W.; Szakacs, J.G.; Duan, S.X.; Hao, Q.; Court, M.H.; von Moltke, L.L.; Greenblatt, D.J.; Kostrubsky, V.; Jeffery, E.H.; Wrighton, S.A.; Gonzalez, F.J.; Sinclair, P.R.; Sinclair, J.F. Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and Cyp2e1 (-/-) mice. Drug Metab. Dispos., 2007, 35(7), 1223-1231.
-
(2007)
Drug Metab. Dispos
, vol.35
, Issue.7
, pp. 1223-1231
-
-
Wolf, K.K.1
Wood, S.G.2
Allard, J.L.3
Hunt, J.A.4
Gorman, N.5
Walton-Strong, B.W.6
Szakacs, J.G.7
Duan, S.X.8
Hao, Q.9
Court, M.H.10
von Moltke, L.L.11
Greenblatt, D.J.12
Kostrubsky, V.13
Jeffery, E.H.14
Wrighton, S.A.15
Gonzalez, F.J.16
Sinclair, P.R.17
Sinclair, J.F.18
-
19
-
-
1642498170
-
Targeted disruption of the olfactory mucosa-specific Cyp2g1 gene: Impact on acetaminophen toxicity in the lateral nasal gland, and tissue-selective effects on Cyp2a5 expression
-
Zhuo, X.; Gu, J.; Behr, M.J.; Swiatek, P.J.; Cui, H.; Zhang, Q.Y.; Xie, Y.; Collins, D.N.; Ding, X. Targeted disruption of the olfactory mucosa-specific Cyp2g1 gene: impact on acetaminophen toxicity in the lateral nasal gland, and tissue-selective effects on Cyp2a5 expression. J. Pharmacol. Exp. Ther., 2004, 308(2), 719-728.
-
(2004)
J. Pharmacol. Exp. Ther
, vol.308
, Issue.2
, pp. 719-728
-
-
Zhuo, X.1
Gu, J.2
Behr, M.J.3
Swiatek, P.J.4
Cui, H.5
Zhang, Q.Y.6
Xie, Y.7
Collins, D.N.8
Ding, X.9
-
20
-
-
57349108805
-
Increased blood pressure in mice lacking cytochrome P450 2J5
-
Athirakul, K.; Bradbury, J.A.; Graves, J.P.; DeGraff, L.M.; Ma, J.; Zhao, Y.; Couse, J.F.; Quigley, R.; Harder, D.R.; Zhao, X.; Imig, J.D.; Pedersen, T.L.; Newman, J.W.; Hammock, B.D.; Conley, A.J.; Korach, K.S.; Coffman, T.M.; Zeldin, D.C. Increased blood pressure in mice lacking cytochrome P450 2J5. FASEB J., 2008, 22(12), 4096-4108.
-
(2008)
FASEB J
, vol.22
, Issue.12
, pp. 4096-4108
-
-
Athirakul, K.1
Bradbury, J.A.2
Graves, J.P.3
DeGraff, L.M.4
Ma, J.5
Zhao, Y.6
Couse, J.F.7
Quigley, R.8
Harder, D.R.9
Zhao, X.10
Imig, J.D.11
Pedersen, T.L.12
Newman, J.W.13
Hammock, B.D.14
Conley, A.J.15
Korach, K.S.16
Coffman, T.M.17
Zeldin, D.C.18
-
21
-
-
36049034219
-
Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism
-
van Herwaarden, A.E.; Wagenaar, E.; van der Kruijssen, C.M.M.; van Waterschoot, R.A.B.; Smit, J.W.; Song, J.Y.; van der Valk, M.A.; van Tellingen, O.; van der Hoorn, J.W.A.; Rosing, H.; Beijnen, J.H.; Schinkel, A.H. Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism. J. Clin. Invest., 2007, 117(11), 3583-3592.
-
(2007)
J. Clin. Invest
, vol.117
, Issue.11
, pp. 3583-3592
-
-
van Herwaarden, A.E.1
Wagenaar, E.2
van der Kruijssen, C.M.M.3
van Waterschoot, R.A.B.4
Smit, J.W.5
Song, J.Y.6
van der Valk, M.A.7
van Tellingen, O.8
van der Hoorn, J.W.A.9
Rosing, H.10
Beijnen, J.H.11
Schinkel, A.H.12
-
22
-
-
40849120766
-
Midazolam metabolism in cytochrome P450 3A knockout mice can be attributed to upregulated CYP2C enzymes
-
van Waterschoot, R.A.B.; van Herwaarden, A.E.; Lagas, J.S.; Sparidans, R.W.; Wagenaar, E.; van der Kruijssen, C.M.M.; Goldstein, J.A.; Zeldin, D.C.; Beijnen, J.H.; Schinkel, A.H. Midazolam metabolism in cytochrome P450 3A knockout mice can be attributed to upregulated CYP2C enzymes. Mol. Pharmacol., 2008, 73(3), 1029-1036.
-
(2008)
Mol. Pharmacol
, vol.73
, Issue.3
, pp. 1029-1036
-
-
van Waterschoot, R.A.B.1
van Herwaarden, A.E.2
Lagas, J.S.3
Sparidans, R.W.4
Wagenaar, E.5
van der Kruijssen, C.M.M.6
Goldstein, J.A.7
Zeldin, D.C.8
Beijnen, J.H.9
Schinkel, A.H.10
-
23
-
-
58249107837
-
Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver
-
van Waterschoot, R.A.B.; Rooswinkel, R.W.; Wagenaar, E.; van der Kruijssen, C.M.M.; van Herwaarden, A.E.; Schinkel, A.H. Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver. FASEB J., 2009, 23(1), 224-231.
-
(2009)
FASEB J
, vol.23
, Issue.1
, pp. 224-231
-
-
van Waterschoot, R.A.B.1
Rooswinkel, R.W.2
Wagenaar, E.3
van der Kruijssen, C.M.M.4
van Herwaarden, A.E.5
Schinkel, A.H.6
-
24
-
-
0035942194
-
Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension
-
Holla, V.R.; Adas, F.; Imig, J.D.; Zhao, X.; Price E.Jr.; Olsen, N.; Kovacs, W.J.; Magnuson, M.A.; Keeney, D.S.; Breyer, M.D.; Falck, J.R.; Waterman, M.R.; Capdevila, J.H. Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension. Proc. Natl. Acad. Sci. USA, 2001, 98(9), 5211-5216.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.9
, pp. 5211-5216
-
-
Holla, V.R.1
Adas, F.2
Imig, J.D.3
Zhao, X.4
Price Jr, E.5
Olsen, N.6
Kovacs, W.J.7
Magnuson, M.A.8
Keeney, D.S.9
Breyer, M.D.10
Falck, J.R.11
Waterman, M.R.12
Capdevila, J.H.13
-
25
-
-
33745197144
-
Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel
-
Nakagawa, K.; Holla, V.R.; Wei, Y.; Wang, W.H.; Gatica, A.; Wei, S.; Mei, S.; Miller, C.M.; Cha, D.R.; Price, E.Jr.; Zent, R.; Pozzi, A.; Breyer, M.D.; Guan, Y.; Falck, J.R.; Waterman, M.R.; Capdevila, J.H. Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel. J. Clin. Invest., 2006, 116(6), 1696-1702.
-
(2006)
J. Clin. Invest
, vol.116
, Issue.6
, pp. 1696-1702
-
-
Nakagawa, K.1
Holla, V.R.2
Wei, Y.3
Wang, W.H.4
Gatica, A.5
Wei, S.6
Mei, S.7
Miller, C.M.8
Cha, D.R.9
Price Jr, E.10
Zent, R.11
Pozzi, A.12
Breyer, M.D.13
Guan, Y.14
Falck, J.R.15
Waterman, M.R.16
Capdevila, J.H.17
-
26
-
-
0029666289
-
Disruption of cholesterol 7α-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation
-
Ishibashi, S.; Schwarz, M.; Frykman, P.K.; Herz, J.; Russell, D.W. Disruption of cholesterol 7α-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation. J. Biol. Chem., 1996, 271(30), 18017-18023.
-
(1996)
J. Biol. Chem
, vol.271
, Issue.30
, pp. 18017-18023
-
-
Ishibashi, S.1
Schwarz, M.2
Frykman, P.K.3
Herz, J.4
Russell, D.W.5
-
27
-
-
0034595445
-
Disruption of the oxysterol 7α- hydroxylase gene in mice
-
Li-Hawkins, J.; Lund, E.G.; Turley, S.D.; Russell, D.W. Disruption of the oxysterol 7α- hydroxylase gene in mice. J. Biol. Chem., 2000, 275(22), 16536-16542.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.22
, pp. 16536-16542
-
-
Li-Hawkins, J.1
Lund, E.G.2
Turley, S.D.3
Russell, D.W.4
-
28
-
-
0036534671
-
Estrogen-dependent regulation of the expression of hepatic Cyp2b and 3a isoforms: Assessment using aromatase-deficient mice
-
Yamada, H.; Gohyama, N.; Honda, S.I.; Hara, T.; Harada, N.; Oguri, K. Estrogen-dependent regulation of the expression of hepatic Cyp2b and 3a isoforms: assessment using aromatase-deficient mice. Toxicol. Appl. Pharmacol., 2002, 180(1), 1-10.
-
(2002)
Toxicol. Appl. Pharmacol
, vol.180
, Issue.1
, pp. 1-10
-
-
Yamada, H.1
Gohyama, N.2
Honda, S.I.3
Hara, T.4
Harada, N.5
Oguri, K.6
-
29
-
-
0037422578
-
Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor
-
Goodwin, B.; Gauthier, K.C.; Umetani, M.; Watson, M.A.; Lochansky, M.I.; Collins, J.L.; Leitersdorf, E.; Mangelsdorf, D.J.; Kliewer, S.A.; Repa, J.J. Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor. Proc. Natl. Acad. Sci. USA, 2003, 100(1), 223-228.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.1
, pp. 223-228
-
-
Goodwin, B.1
Gauthier, K.C.2
Umetani, M.3
Watson, M.A.4
Lochansky, M.I.5
Collins, J.L.6
Leitersdorf, E.7
Mangelsdorf, D.J.8
Kliewer, S.A.9
Repa, J.J.10
-
30
-
-
0141459395
-
Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover
-
Xie, C.; Lund, E.G.; Turley, S.D.; Russell, D.W.; Dietschy, J.M. Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover. J. Lipid Res., 2003, 44(9), 1780-1789.
-
(2003)
J. Lipid Res
, vol.44
, Issue.9
, pp. 1780-1789
-
-
Xie, C.1
Lund, E.G.2
Turley, S.D.3
Russell, D.W.4
Dietschy, J.M.5
-
31
-
-
77649125221
-
P450-reductase knockout mouse models for drug metabolism research
-
Abstract 11
-
Ding, X.; Fang, C.; Wei, Y.; Zhou, X.; Gu, J.; Zhang, Q.Y. P450-reductase knockout mouse models for drug metabolism research. Drug Metab. Rev., 40(Suppl. 3), Abstract 11, 2009.
-
(2009)
Drug Metab. Rev
, vol.40
, Issue.SUPPL. 3
-
-
Ding, X.1
Fang, C.2
Wei, Y.3
Zhou, X.4
Gu, J.5
Zhang, Q.Y.6
-
32
-
-
84925563414
-
Role of Cyp2a5 in the metabolism of nicotine and cotinine: Insights from a Cyp2a5-null mouse model and a CYP2A6-humanized mouse model
-
Oct 18-22, Baltimore, Abstract 54
-
th North American Regional ISSX Meeting, Oct 18-22, Baltimore, Abstract 54, 2009
-
(2009)
th North American Regional ISSX Meeting
-
-
Zhou, X.1
Zhuo, X.2
Xie, F.3
Kluetzman, K.4
Shu, Y.Z.5
Humphreys, W.6
Ding, X.7
-
33
-
-
0037440941
-
Tissue-specific induction of cytochromes P450 1A1 and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in engineered C57BL/6J mice of arylhydrocarbon receptor gene
-
Shimada, T.; Sugie, A.; Shindo, M.; Nakajima, T.; Azuma, E.; Hashimoto, M.; Inoue, K. Tissue-specific induction of cytochromes P450 1A1 and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in engineered C57BL/6J mice of arylhydrocarbon receptor gene. Toxicol. Appl. Pharmacol., 2003, 187(1), 1-10.
-
(2003)
Toxicol. Appl. Pharmacol
, vol.187
, Issue.1
, pp. 1-10
-
-
Shimada, T.1
Sugie, A.2
Shindo, M.3
Nakajima, T.4
Azuma, E.5
Hashimoto, M.6
Inoue, K.7
-
34
-
-
0036765785
-
Nuclear pregnane X receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification
-
Maglich, J.M.; Stoltz, C.M.; Goodwin, B.; Hawkins-Brown, D.; Moore, J.T.; Kliewer, S.A. Nuclear pregnane X receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification. Mol. Pharmacol., 2002, 62(3), 638-646.
-
(2002)
Mol. Pharmacol
, vol.62
, Issue.3
, pp. 638-646
-
-
Maglich, J.M.1
Stoltz, C.M.2
Goodwin, B.3
Hawkins-Brown, D.4
Moore, J.T.5
Kliewer, S.A.6
-
35
-
-
10344224570
-
The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity
-
Zhang, J.; Huang, W.; Qatanani, M.; Evans, R.M.; Moore, D.D. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity. J. Biol. Chem., 2004, 279(47), 49517-49522.
-
(2004)
J. Biol. Chem
, vol.279
, Issue.47
, pp. 49517-49522
-
-
Zhang, J.1
Huang, W.2
Qatanani, M.3
Evans, R.M.4
Moore, D.D.5
-
36
-
-
7044237266
-
-
Anakk, S.; Kalsotra, A.; Kikuta, Y.; Huang, W.; Zhang, J.; Staudinger, J.L; Moore, D.D.; Strobel, H.W. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11. Pharmacogenom. J., 2004, 4(2), 91-101.
-
Anakk, S.; Kalsotra, A.; Kikuta, Y.; Huang, W.; Zhang, J.; Staudinger, J.L; Moore, D.D.; Strobel, H.W. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11. Pharmacogenom. J., 2004, 4(2), 91-101.
-
-
-
-
37
-
-
66449101442
-
Constitutive androstane receptor-mediated changes in bile acid composition contributes to hepatoprotection from lithocholic acid-induced liver injury in mice
-
Beilke, L.D.; Aleksunes, L.M.; Holland, R.D.; Besselsen, D.G.; Beger, R.D.; Klaassen, C.D.; Cherrington, N.J. Constitutive androstane receptor-mediated changes in bile acid composition contributes to hepatoprotection from lithocholic acid-induced liver injury in mice. Drug Metab. Dispos., 2009, 37(5), 1035-1045.
-
(2009)
Drug Metab. Dispos
, vol.37
, Issue.5
, pp. 1035-1045
-
-
Beilke, L.D.1
Aleksunes, L.M.2
Holland, R.D.3
Besselsen, D.G.4
Beger, R.D.5
Klaassen, C.D.6
Cherrington, N.J.7
-
38
-
-
0035853165
-
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity
-
Staudinger, J.L.; Goodwin, B.; Jones, S.A.; Hawkins-Brown, D.; MacKenzie, K.I.; LaTour, A.; Liu, Y.; Klaassen, C.D.; Brown, K.K.; Reinhard, J.; Willson, T.M.; Koller, B.H.; Kliewer, S.A. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proc. Natl. Acad. Sci. USA, 2001, 98(6), 3369-3374.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.6
, pp. 3369-3374
-
-
Staudinger, J.L.1
Goodwin, B.2
Jones, S.A.3
Hawkins-Brown, D.4
MacKenzie, K.I.5
LaTour, A.6
Liu, Y.7
Klaassen, C.D.8
Brown, K.K.9
Reinhard, J.10
Willson, T.M.11
Koller, B.H.12
Kliewer, S.A.13
-
39
-
-
0035853057
-
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids
-
Xie, W.; Radominska-Pandya, A.; Shi, Y.; Simon, C.M.; Nelson, M.C.; Ong, E.S.; Waxman, D.J.; Evans, R.M. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proc. Natl. Acad. Sci. USA, 2001, 98(6), 3375-3380.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.6
, pp. 3375-3380
-
-
Xie, W.1
Radominska-Pandya, A.2
Shi, Y.3
Simon, C.M.4
Nelson, M.C.5
Ong, E.S.6
Waxman, D.J.7
Evans, R.M.8
-
40
-
-
0034782509
-
Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor
-
Staudinger, J.; Liu, Y.; Madan, A.; Habeebu, S.; Klaassen, C.D. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor. Drug Metab. Dispos., 2001, 29(11), 1467-1472.
-
(2001)
Drug Metab. Dispos
, vol.29
, Issue.11
, pp. 1467-1472
-
-
Staudinger, J.1
Liu, Y.2
Madan, A.3
Habeebu, S.4
Klaassen, C.D.5
-
41
-
-
0035570381
-
Fibrates suppress bile acid synthesis via peroxisome proliferator- activated receptor-α-mediated downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase expression
-
Post, S.M.; Duez, H.; Gervois, P.P.; Staels, B.; Kuipers, F.; Princen, H.M.G. Fibrates suppress bile acid synthesis via peroxisome proliferator- activated receptor-α-mediated downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase expression. Arterioscler. Thromb. Vasc. Biol., 2001, 21(11), 1840-1845.
-
(2001)
Arterioscler. Thromb. Vasc. Biol
, vol.21
, Issue.11
, pp. 1840-1845
-
-
Post, S.M.1
Duez, H.2
Gervois, P.P.3
Staels, B.4
Kuipers, F.5
Princen, H.M.G.6
-
42
-
-
67650242396
-
Opposing roles of peroxisome proliferator-activated receptor α and growth hormone in the regulation of CYP4A11 expression in a transgenic mouse model
-
Savas, Ü.; Machemer, D.E.W.; Hsu, M.H.; Gaynor, P.; Lasker, J.M.; Tukey, R.H.; Johnson, E.F. Opposing roles of peroxisome proliferator-activated receptor α and growth hormone in the regulation of CYP4A11 expression in a transgenic mouse model. J. Biol. Chem., 2009, 284(24), 16541-16552.
-
(2009)
J. Biol. Chem
, vol.284
, Issue.24
, pp. 16541-16552
-
-
Savas, U.1
Machemer, D.E.W.2
Hsu, M.H.3
Gaynor, P.4
Lasker, J.M.5
Tukey, R.H.6
Johnson, E.F.7
-
43
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα
-
Peet, D.J.; Turley, S.D.; Ma, W.; Janowski, B.A.; Lobaccaro, J.M.A.; Hammer, R.E.; Mangelsdorf, D.J. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα. Cell, 1998, 93(5), 693-704.
-
(1998)
Cell
, vol.93
, Issue.5
, pp. 693-704
-
-
Peet, D.J.1
Turley, S.D.2
Ma, W.3
Janowski, B.A.4
Lobaccaro, J.M.A.5
Hammer, R.E.6
Mangelsdorf, D.J.7
-
44
-
-
23244432637
-
LXR deficiency and cholesterol feeding affect the expression and phenobarbital-mediated induction of cytochromes P450 in mouse liver
-
Gnerre, C.; Schuster, G.U.; Roth, A.; Handschin, C.; Johansson, L.; Looser, R.; Parini, P.; Podvinec, M.; Robertsson, K.; Gustafsson, J.Å.; Meyer, U.A. LXR deficiency and cholesterol feeding affect the expression and phenobarbital-mediated induction of cytochromes P450 in mouse liver. J. Lipid Res., 2005, 46(8), 1633-1642.
-
(2005)
J. Lipid Res
, vol.46
, Issue.8
, pp. 1633-1642
-
-
Gnerre, C.1
Schuster, G.U.2
Roth, A.3
Handschin, C.4
Johansson, L.5
Looser, R.6
Parini, P.7
Podvinec, M.8
Robertsson, K.9
Gustafsson, J.A.10
Meyer, U.A.11
-
45
-
-
33847699765
-
Activation of LXRs prevents bile acid toxicity and cholestasis in female mice
-
Uppal, H.; Saini, S.P.S.; Moschetta, A.; Mu, Y.; Zhou, J.; Gong, H.; Zhai, Y.; Ran, S.; Michalopoulos, G.K.; Mangelsdorf, D.J.; Xie, W. Activation of LXRs prevents bile acid toxicity and cholestasis in female mice. Hepatology, 2007, 45(2), 422-432.
-
(2007)
Hepatology
, vol.45
, Issue.2
, pp. 422-432
-
-
Uppal, H.1
Saini, S.P.S.2
Moschetta, A.3
Mu, Y.4
Zhou, J.5
Gong, H.6
Zhai, Y.7
Ran, S.8
Michalopoulos, G.K.9
Mangelsdorf, D.J.10
Xie, W.11
-
46
-
-
57349179929
-
A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4
-
Ma, X.; Cheung, C.; Krausz, K.W.; Shah, Y.M.; Wang, T.; Idle, J.R.; Gonzalez, F.J. A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4. Drug Metab. Dispos., 2008, 36(12), 2506-2512.
-
(2008)
Drug Metab. Dispos
, vol.36
, Issue.12
, pp. 2506-2512
-
-
Ma, X.1
Cheung, C.2
Krausz, K.W.3
Shah, Y.M.4
Wang, T.5
Idle, J.R.6
Gonzalez, F.J.7
-
47
-
-
33845267470
-
The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis
-
Nebert, D.W.; Dalton, T.P. The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis. Nat. Rev. Cancer, 2006, 6(12), 947-960.
-
(2006)
Nat. Rev. Cancer
, vol.6
, Issue.12
, pp. 947-960
-
-
Nebert, D.W.1
Dalton, T.P.2
-
48
-
-
9044254525
-
P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
-
Nelson, D.R.; Koymans, L.; Kamataki, T.; Stegeman, J.J.; Feyereisen, R.; Waxman, D.J.; Waterman, M.R.; Gotoh, O.; Coon, M.J.; Estabrook, R.W.; Gunsalus, I.C.; Nebert, D.W. P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics, 1996, 6(1), 1-42.
-
(1996)
Pharmacogenetics
, vol.6
, Issue.1
, pp. 1-42
-
-
Nelson, D.R.1
Koymans, L.2
Kamataki, T.3
Stegeman, J.J.4
Feyereisen, R.5
Waxman, D.J.6
Waterman, M.R.7
Gotoh, O.8
Coon, M.J.9
Estabrook, R.W.10
Gunsalus, I.C.11
Nebert, D.W.12
-
49
-
-
0031909277
-
Detection of cytochrome P4501A in several species using antibody against a synthetic peptide derived from rainbow trout cytochrome P4501A1
-
Lin, S.; Bullock, P.L.; Addison, R.F.; Bandiera, S.M. Detection of cytochrome P4501A in several species using antibody against a synthetic peptide derived from rainbow trout cytochrome P4501A1. Environ. Toxicol. Chem., 1998, 17(3), 439-445.
-
(1998)
Environ. Toxicol. Chem
, vol.17
, Issue.3
, pp. 439-445
-
-
Lin, S.1
Bullock, P.L.2
Addison, R.F.3
Bandiera, S.M.4
-
50
-
-
34248190848
-
Lipid reserve biodynamics and magnification of persistent organic pollutants in spawning sockeye salmon (Oncorhynchus nerka) from the Fraser river, British Columbia
-
Kelly, B.C.; Gray, S.L.; Ikonomou, G.; Macdonald, J.S.; Bandiera, S.M.; Hrycay, E.G. Lipid reserve biodynamics and magnification of persistent organic pollutants in spawning sockeye salmon (Oncorhynchus nerka) from the Fraser river, British Columbia. Environ. Sci. Technol., 2007, 41(9), 3083-3089.
-
(2007)
Environ. Sci. Technol
, vol.41
, Issue.9
, pp. 3083-3089
-
-
Kelly, B.C.1
Gray, S.L.2
Ikonomou, G.3
Macdonald, J.S.4
Bandiera, S.M.5
Hrycay, E.G.6
-
51
-
-
0028937648
-
Catalytic and immunologic characterization of hepatic and lung cytochromes P450 in the polar bear
-
Bandiera, S.M.; Torok, S.M.; Lin, S.; Ramsay, M.A.; Norstrom, R.J. Catalytic and immunologic characterization of hepatic and lung cytochromes P450 in the polar bear. Biochem. Pharmacol., 1995, 49(8), 1135-1146.
-
(1995)
Biochem. Pharmacol
, vol.49
, Issue.8
, pp. 1135-1146
-
-
Bandiera, S.M.1
Torok, S.M.2
Lin, S.3
Ramsay, M.A.4
Norstrom, R.J.5
-
53
-
-
0033564423
-
Immunochemical analysis of liver microsomal cytochromes P450 of the American alligator, Alligator mississippiensis
-
Ertl, R.P.; Bandiera, S.M.; Buhler, D.R.; Stegeman, J.J.; Winston, G.W. Immunochemical analysis of liver microsomal cytochromes P450 of the American alligator, Alligator mississippiensis. Toxicol. Appl. Pharmacol., 1999, 157(3), 157-165.
-
(1999)
Toxicol. Appl. Pharmacol
, vol.157
, Issue.3
, pp. 157-165
-
-
Ertl, R.P.1
Bandiera, S.M.2
Buhler, D.R.3
Stegeman, J.J.4
Winston, G.W.5
-
54
-
-
33847415936
-
Cytochrome P450 1A expression and organochlorine contaminants in harbour seals (Phoca vitulina): Evaluating a biopsy approach
-
Assunção, M.G.L.; Miller, K.A.; Dangerfield, N.J.; Bandiera, S.M.; Ross, P.S. Cytochrome P450 1A expression and organochlorine contaminants in harbour seals (Phoca vitulina): evaluating a biopsy approach. Comp. Biochem. Physiol. C Toxicol. Pharmacol., 2007, 145(2), 256-264.
-
(2007)
Comp. Biochem. Physiol. C Toxicol. Pharmacol
, vol.145
, Issue.2
, pp. 256-264
-
-
Assunção, M.G.L.1
Miller, K.A.2
Dangerfield, N.J.3
Bandiera, S.M.4
Ross, P.S.5
-
55
-
-
38149016903
-
Sexually dimorphic gene expression in the heart of mice and men
-
Isensee, J.; Witt, H.; Pregla, R.; Hetzer, R.; Regitz-Zagrosek, V.; Noppinger, P.R. Sexually dimorphic gene expression in the heart of mice and men. J. Mol. Med., 2008, 86(1), 61-74.
-
(2008)
J. Mol. Med
, vol.86
, Issue.1
, pp. 61-74
-
-
Isensee, J.1
Witt, H.2
Pregla, R.3
Hetzer, R.4
Regitz-Zagrosek, V.5
Noppinger, P.R.6
-
56
-
-
2942585589
-
Major molecular differences between mammalian sexes are involved in drug metabolism and renal function
-
Rinn, J.L.; Rozowsky, J.S.; Laurenzi, I.J.; Petersen, P.H.; Zou, K.; Zhong, W.; Gerstein, M.; Snyder, M. Major molecular differences between mammalian sexes are involved in drug metabolism and renal function. Dev. Cell, 2004, 6(6), 791-800.
-
(2004)
Dev. Cell
, vol.6
, Issue.6
, pp. 791-800
-
-
Rinn, J.L.1
Rozowsky, J.S.2
Laurenzi, I.J.3
Petersen, P.H.4
Zou, K.5
Zhong, W.6
Gerstein, M.7
Snyder, M.8
-
57
-
-
0027102629
-
Differences in regulation of gene expression between Cyp1a-1 and Cyp1a-2 in adult mouse hepatocytes in primary culture
-
Nemoto, N.; Sakurai, J. Differences in regulation of gene expression between Cyp1a-1 and Cyp1a-2 in adult mouse hepatocytes in primary culture. Carcinogenesis, 1992, 13(12), 2249-2254.
-
(1992)
Carcinogenesis
, vol.13
, Issue.12
, pp. 2249-2254
-
-
Nemoto, N.1
Sakurai, J.2
-
58
-
-
0025172709
-
Chlorinated biphenyls induce cytochrome P4501A2 and uroporphyrin accumulation in cultures of mouse hepatocytes
-
Sinclair, P.R.; Bement, W.J.; Lambrecht, R.W.; Gorman, N.; Sinclair, J.F. Chlorinated biphenyls induce cytochrome P4501A2 and uroporphyrin accumulation in cultures of mouse hepatocytes. Arch. Biochem. Biophys., 1990, 281(2), 225-232.
-
(1990)
Arch. Biochem. Biophys
, vol.281
, Issue.2
, pp. 225-232
-
-
Sinclair, P.R.1
Bement, W.J.2
Lambrecht, R.W.3
Gorman, N.4
Sinclair, J.F.5
-
59
-
-
0036236050
-
Identification of the cytochromes P450 that catalyze coumarin 3,4-epoxidation and 3-hydroxylation
-
Born, S.L.; Caudill, D.; Fliter, K.L.; Purdon, M.P. Identification of the cytochromes P450 that catalyze coumarin 3,4-epoxidation and 3-hydroxylation. Drug Metab. Dispos., 2002, 30(5), 483-487.
-
(2002)
Drug Metab. Dispos
, vol.30
, Issue.5
, pp. 483-487
-
-
Born, S.L.1
Caudill, D.2
Fliter, K.L.3
Purdon, M.P.4
-
60
-
-
34347404063
-
18O stable isotope labeling
-
18O stable isotope labeling. Mol. Cell. Proteomics, 2007, 6(6), 953-962.
-
(2007)
Mol. Cell. Proteomics
, vol.6
, Issue.6
, pp. 953-962
-
-
Lane, C.S.1
Wang, Y.2
Betts, R.3
Griffiths, W.J.4
Patterson, L.H.5
-
61
-
-
0030917089
-
Hydrogen peroxide supports human and rat cytochrome P450 1A2-catalyzed 2-amino-3-methylimidazo[4, 5-f]quinoline bioactivation to mutagenic metabolites: Significance of cytochrome P450 peroxygenase
-
Anari, M.R.; Josephy, P.D.; Henry, T.; O'Brien, P.J. Hydrogen peroxide supports human and rat cytochrome P450 1A2-catalyzed 2-amino-3-methylimidazo[4, 5-f]quinoline bioactivation to mutagenic metabolites: significance of cytochrome P450 peroxygenase. Chem. Res. Toxicol., 1997, 10(5), 582-588
-
(1997)
Chem. Res. Toxicol
, vol.10
, Issue.5
, pp. 582-588
-
-
Anari, M.R.1
Josephy, P.D.2
Henry, T.3
O'Brien, P.J.4
-
62
-
-
84925563306
-
Relative potential of anti-HIV protease inhibitors to induce cytochrome P450 enzymes and transporters in human hepatocytes
-
Oct 18-22, Baltimore, Abstract 180
-
th North American Regional ISSX Meeting, Oct 18-22, Baltimore, Abstract 180, 2009.
-
(2009)
th North American Regional ISSX Meeting
-
-
Liu, L.1
Mugundu, G.M.2
Samineni, D.3
Kirby, B.J.4
Desai, P.5
Unadkat, J.6
-
63
-
-
0034234716
-
Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent
-
Siewert, E.; Bort, R.; Kluge, R.; Heinrich, P.C.; Castell, J.; Jover, R. Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent. Hepatology, 2000, 32(1), 49-55.
-
(2000)
Hepatology
, vol.32
, Issue.1
, pp. 49-55
-
-
Siewert, E.1
Bort, R.2
Kluge, R.3
Heinrich, P.C.4
Castell, J.5
Jover, R.6
-
64
-
-
10644266103
-
Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones
-
Payne, A.H.; Hales, D.B. Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. Endocr. Rev., 2004, 25(6), 947-970.
-
(2004)
Endocr. Rev
, vol.25
, Issue.6
, pp. 947-970
-
-
Payne, A.H.1
Hales, D.B.2
-
65
-
-
33846385587
-
Mammalian cytochromes P450-importance of tissue specificity
-
Seliskar, M.; Rozman, D. Mammalian cytochromes P450-importance of tissue specificity. Biochim. Biophys. Acta, 2007, 1770(3), 458-466.
-
(2007)
Biochim. Biophys. Acta
, vol.1770
, Issue.3
, pp. 458-466
-
-
Seliskar, M.1
Rozman, D.2
-
66
-
-
0344586817
-
Severe cholestasis induced by cholic acid feeding in knockout mice of sister of P-glycoprotein
-
Wang, R.; Lam, P.; Liu, L.; Forrest, D.; Yousef, I.M.; Mignault, D.; Phillips, M.J.; Ling, V. Severe cholestasis induced by cholic acid feeding in knockout mice of sister of P-glycoprotein. Hepatology, 2003, 38(6), 1489-1499.
-
(2003)
Hepatology
, vol.38
, Issue.6
, pp. 1489-1499
-
-
Wang, R.1
Lam, P.2
Liu, L.3
Forrest, D.4
Yousef, I.M.5
Mignault, D.6
Phillips, M.J.7
Ling, V.8
-
67
-
-
0038706167
-
Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues
-
Choudhary, D.; Jansson, I.; Schenkman, J.B.; Sarfarazi, M.; Stoilov, I. Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues. Arch. Biochem. Biophys., 2003, 414(1), 91-100.
-
(2003)
Arch. Biochem. Biophys
, vol.414
, Issue.1
, pp. 91-100
-
-
Choudhary, D.1
Jansson, I.2
Schenkman, J.B.3
Sarfarazi, M.4
Stoilov, I.5
-
68
-
-
14744302949
-
Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues
-
Choudhary, D.; Jansson, I.; Stoilov, I.; Sarfarazi, M.; Schenkman, J.B. Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues. Arch. Biochem. Biophys., 2005, 436(1), 50-61.
-
(2005)
Arch. Biochem. Biophys
, vol.436
, Issue.1
, pp. 50-61
-
-
Choudhary, D.1
Jansson, I.2
Stoilov, I.3
Sarfarazi, M.4
Schenkman, J.B.5
-
69
-
-
34249009984
-
Expression and function of cytochrome P450 in brain drug metabolism
-
Meyer, R.P.; Gehlhaus, M.; Knoth, R.; Volk, B. Expression and function of cytochrome P450 in brain drug metabolism. Curr. Drug Metab., 2007, 8(4), 297-306.
-
(2007)
Curr. Drug Metab
, vol.8
, Issue.4
, pp. 297-306
-
-
Meyer, R.P.1
Gehlhaus, M.2
Knoth, R.3
Volk, B.4
-
70
-
-
34047124819
-
Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
-
Ma, X.; Idle, J.R.; Malfatti, M.A.; Krausz, K.W.; Nebert, D.W.; Chen, C.S.; Felton, J.S.; Waxman, D.J.; Gonzalez, F.J. Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Carcinogenesis, 2007, 28(3), 732-737.
-
(2007)
Carcinogenesis
, vol.28
, Issue.3
, pp. 732-737
-
-
Ma, X.1
Idle, J.R.2
Malfatti, M.A.3
Krausz, K.W.4
Nebert, D.W.5
Chen, C.S.6
Felton, J.S.7
Waxman, D.J.8
Gonzalez, F.J.9
-
71
-
-
38949159278
-
Expression, activity and regulation of CYP3A in human and rodent brain
-
Woodland, C.; Huang, T.T.; Gryz, E.; Bendayan, R. Expression, activity and regulation of CYP3A in human and rodent brain. Drug Metab. Rev., 2008, 40(1), 149-168.
-
(2008)
Drug Metab. Rev
, vol.40
, Issue.1
, pp. 149-168
-
-
Woodland, C.1
Huang, T.T.2
Gryz, E.3
Bendayan, R.4
-
72
-
-
33751397645
-
The cytochromes P450 (CYP) response to allergic inflammation of the lung
-
Stoilov, I.; Krueger, W.; Mankowski, D.; Guernsey, L.; Kaur, A.; Glynn, J.; Thrall, R.S. The cytochromes P450 (CYP) response to allergic inflammation of the lung. Arch. Biochem. Biophys., 2006, 456(1), 30-38.
-
(2006)
Arch. Biochem. Biophys
, vol.456
, Issue.1
, pp. 30-38
-
-
Stoilov, I.1
Krueger, W.2
Mankowski, D.3
Guernsey, L.4
Kaur, A.5
Glynn, J.6
Thrall, R.S.7
-
73
-
-
0142212150
-
Characterization of mouse small intestinal cytochrome P450 expression
-
Zhang, Q.Y.; Dunbar, D.; Kaminsky, L.S. Characterization of mouse small intestinal cytochrome P450 expression. Drug Metab. Dispos., 2003, 31(11), 1346-1351.
-
(2003)
Drug Metab. Dispos
, vol.31
, Issue.11
, pp. 1346-1351
-
-
Zhang, Q.Y.1
Dunbar, D.2
Kaminsky, L.S.3
-
74
-
-
0033049368
-
Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization
-
Dey, A.; Jones, J.E.; Nebert, D.W. Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization. Biochem. Pharmacol., 1999, 58(3), 525-537.
-
(1999)
Biochem. Pharmacol
, vol.58
, Issue.3
, pp. 525-537
-
-
Dey, A.1
Jones, J.E.2
Nebert, D.W.3
-
75
-
-
0015147501
-
Cytochrome P-450 as a microsomal peroxidase utilizing a lipid peroxide substrate
-
Hrycay, E.G.; O'Brien, P.J. Cytochrome P-450 as a microsomal peroxidase utilizing a lipid peroxide substrate. Arch. Biochem. Biophys., 1971, 147(1), 14-27.
-
(1971)
Arch. Biochem. Biophys
, vol.147
, Issue.1
, pp. 14-27
-
-
Hrycay, E.G.1
O'Brien, P.J.2
-
76
-
-
0037260154
-
Realtime polymerase chain reaction analysis of CYP1B1 gene expression in human liver
-
Chang, T.K.H.; Chen, J.; Pillay, V.; Ho, J.Y.; Bandiera, S.M. Realtime polymerase chain reaction analysis of CYP1B1 gene expression in human liver. Toxicol. Sci., 2003, 71(1), 11-19.
-
(2003)
Toxicol. Sci
, vol.71
, Issue.1
, pp. 11-19
-
-
Chang, T.K.H.1
Chen, J.2
Pillay, V.3
Ho, J.Y.4
Bandiera, S.M.5
-
77
-
-
28144458592
-
Simultaneous measurement of 23 isoforms from the human cytochrome P450 families 1 to 3 by quantitative reverse transcriptase-polymerase chain reaction
-
Girault, I.; Rougier, N.; Chesné, C.; Lidereau, R.; Beaune, P.; Bièche, I.; de Waziers, I. Simultaneous measurement of 23 isoforms from the human cytochrome P450 families 1 to 3 by quantitative reverse transcriptase-polymerase chain reaction. Drug Metab. Dispos., 2005, 33(12), 1803-1810.
-
(2005)
Drug Metab. Dispos
, vol.33
, Issue.12
, pp. 1803-1810
-
-
Girault, I.1
Rougier, N.2
Chesné, C.3
Lidereau, R.4
Beaune, P.5
Bièche, I.6
de Waziers, I.7
-
78
-
-
33749364917
-
Cytochrome P450 enzymes: Central players in cardiovascular health and disease
-
Elbekai, R.H.; El-Kadi, A.O.S. Cytochrome P450 enzymes: central players in cardiovascular health and disease. Pharmacol. Ther., 2006, 112(2), 564-587.
-
(2006)
Pharmacol. Ther
, vol.112
, Issue.2
, pp. 564-587
-
-
Elbekai, R.H.1
El-Kadi, A.O.S.2
-
79
-
-
41549114526
-
Xenobiotic-induced transcriptional regulation of xenobiotic metabolizing enzymes of the cytochrome P450 superfamily in human extrahepatic tissues
-
Pavek, P.; Dvorak, Z. Xenobiotic-induced transcriptional regulation of xenobiotic metabolizing enzymes of the cytochrome P450 superfamily in human extrahepatic tissues. Curr. Drug Metab., 2008, 9(2), 129-143.
-
(2008)
Curr. Drug Metab
, vol.9
, Issue.2
, pp. 129-143
-
-
Pavek, P.1
Dvorak, Z.2
-
80
-
-
0032894224
-
Quantitative RT-PCR: Pitfalls and potential
-
Freeman, W.M.; Walker, S.J.; Vrana, K.E. Quantitative RT-PCR: pitfalls and potential. BioTechniques, 1999, 26(1), 112-125.
-
(1999)
BioTechniques
, vol.26
, Issue.1
, pp. 112-125
-
-
Freeman, W.M.1
Walker, S.J.2
Vrana, K.E.3
-
81
-
-
0034091584
-
Use of a novel real-time quantitative reverse transcription-polymerase chain reaction method to study the effects of cytokines on cytochrome P450 mRNA expression in mouse liver
-
Pan, J.; Xiang, Q.; Ball, S. Use of a novel real-time quantitative reverse transcription-polymerase chain reaction method to study the effects of cytokines on cytochrome P450 mRNA expression in mouse liver. Drug Metab. Dispos., 2000, 28(6), 709-713.
-
(2000)
Drug Metab. Dispos
, vol.28
, Issue.6
, pp. 709-713
-
-
Pan, J.1
Xiang, Q.2
Ball, S.3
-
82
-
-
0041922374
-
Tissue distribution of mRNA expression of human cytochrome P450 isoforms assessed by high-sensitivity real-time reverse transcription PCR
-
Nishimura, M.; Yaguti, H.; Yoshitsugu, H.; Naito, S.; Satoh, T. Tissue distribution of mRNA expression of human cytochrome P450 isoforms assessed by high-sensitivity real-time reverse transcription PCR. Yakugaku Zasshi, 2003, 123(5), 369-375.
-
(2003)
Yakugaku Zasshi
, vol.123
, Issue.5
, pp. 369-375
-
-
Nishimura, M.1
Yaguti, H.2
Yoshitsugu, H.3
Naito, S.4
Satoh, T.5
-
83
-
-
0027179679
-
Methoxyresorufin and benzyloxyresorufin: Substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse
-
Nerurkar, P.V.; Park, S.S.; Thomas, P.E.; Nims, R.W.; Lubet, R.A. Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse. Biochem. Pharmacol., 1993, 46(5), 933-943.
-
(1993)
Biochem. Pharmacol
, vol.46
, Issue.5
, pp. 933-943
-
-
Nerurkar, P.V.1
Park, S.S.2
Thomas, P.E.3
Nims, R.W.4
Lubet, R.A.5
-
84
-
-
0344442736
-
Spectral interactions of tetrachlorobiphenyls with hepatic microsomal cytochrome P450 enzymes
-
Hrycay, E.G.; Bandiera, S.M. Spectral interactions of tetrachlorobiphenyls with hepatic microsomal cytochrome P450 enzymes. Chem.-Biol. Interact., 2003, 146(3), 285-296.
-
(2003)
Chem.-Biol. Interact
, vol.146
, Issue.3
, pp. 285-296
-
-
Hrycay, E.G.1
Bandiera, S.M.2
-
85
-
-
47049092256
-
-
Kania-Korwel, I.; Hrycay, E.G.; Bandiera, S.M.; Lehmler, H.J. 2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) atropisomers interact enantioselectively with hepatic microsomal cytochrome P450 enzymes. Chem. Res. Toxicol., 2008, 21(6), 1295-1303.
-
Kania-Korwel, I.; Hrycay, E.G.; Bandiera, S.M.; Lehmler, H.J. 2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) atropisomers interact enantioselectively with hepatic microsomal cytochrome P450 enzymes. Chem. Res. Toxicol., 2008, 21(6), 1295-1303.
-
-
-
-
86
-
-
0018576948
-
Structural gene products of the Ah locus. Genetic and immunochemical evidence for two forms of mouse liver cytochrome P-450 induced by 3-methylcholanthrene
-
Negishi, M.; Nebert, D.W. Structural gene products of the Ah locus. Genetic and immunochemical evidence for two forms of mouse liver cytochrome P-450 induced by 3-methylcholanthrene. J. Biol. Chem., 1979, 254(21), 11015-11023.
-
(1979)
J. Biol. Chem
, vol.254
, Issue.21
, pp. 11015-11023
-
-
Negishi, M.1
Nebert, D.W.2
-
87
-
-
0032609107
-
Constitutive expression and induction of CYP1B1 mRNA in the mouse
-
Ryu, D.Y.; Hodgson, E. Constitutive expression and induction of CYP1B1 mRNA in the mouse. J Biochem. Mol. Toxicol., 1999, 13(5), 249-251.
-
(1999)
J Biochem. Mol. Toxicol
, vol.13
, Issue.5
, pp. 249-251
-
-
Ryu, D.Y.1
Hodgson, E.2
-
88
-
-
34249048046
-
Cyp1b1 protein in the mouse eye during development: An immunohistochemical study
-
Choudhary, D.; Jansson, I.; Rezaul, K.; Han, D.K.M.; Sarfarazi, M.; Schenkman, J.B. Cyp1b1 protein in the mouse eye during development: an immunohistochemical study. Drug Metab. Dispos., 2007, 35(6), 987-994.
-
(2007)
Drug Metab. Dispos
, vol.35
, Issue.6
, pp. 987-994
-
-
Choudhary, D.1
Jansson, I.2
Rezaul, K.3
Han, D.K.M.4
Sarfarazi, M.5
Schenkman, J.B.6
-
89
-
-
0025907749
-
Purification and immunological characterization of a novel cytochrome P450 from C3H/10T1/2 cells
-
Pottenger, L.H.; Christou, M.; Jefcoate, C.R. Purification and immunological characterization of a novel cytochrome P450 from C3H/10T1/2 cells. Arch. Biochem. Biophys., 1991, 286(2), 488-497.
-
(1991)
Arch. Biochem. Biophys
, vol.286
, Issue.2
, pp. 488-497
-
-
Pottenger, L.H.1
Christou, M.2
Jefcoate, C.R.3
-
90
-
-
0028339108
-
Mouse cytochrome P-450EF, representative of a new 1B subfamily of cytochrome P-450s. Cloning, sequence determination, and tissue expression
-
Savas, Ü.; Bhattacharyya, K.K.; Christou, M.; Alexander, D.L.; Jefcoate, C.R. Mouse cytochrome P-450EF, representative of a new 1B subfamily of cytochrome P-450s. Cloning, sequence determination, and tissue expression. J. Biol. Chem., 1994, 269(21), 14905-14911.
-
(1994)
J. Biol. Chem
, vol.269
, Issue.21
, pp. 14905-14911
-
-
Savas, U.1
Bhattacharyya, K.K.2
Christou, M.3
Alexander, D.L.4
Jefcoate, C.R.5
-
91
-
-
34547899883
-
Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues
-
Bièche, I.; Narjoz, C.; Asselah, T.; Vacher, S.; Marcellin, P.; Lidereau, R.; Beaune, P.; de Waziers, I. Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues. Pharmacogenet. Genomics, 2007, 17(9), 731-742.
-
(2007)
Pharmacogenet. Genomics
, vol.17
, Issue.9
, pp. 731-742
-
-
Bièche, I.1
Narjoz, C.2
Asselah, T.3
Vacher, S.4
Marcellin, P.5
Lidereau, R.6
Beaune, P.7
de Waziers, I.8
-
92
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
Shimada, T.; Yamazaki, H.; Mimura, M.; Inui, Y.; Guengerich, F.P. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther., 1994, 270(1), 414-423.
-
(1994)
J. Pharmacol. Exp. Ther
, vol.270
, Issue.1
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Inui, Y.4
Guengerich, F.P.5
-
93
-
-
0345390836
-
Development of an antipeptide antibody that binds to the C-terminal region of human CYP1B1
-
Tang, Y.M.; Chen, G.F.; Thompson, P.A.; Lin, D.X.; Lang, N.P.; Kadlubar, F.F. Development of an antipeptide antibody that binds to the C-terminal region of human CYP1B1. Drug Metab. Dispos., 1999, 27(2), 274-280.
-
(1999)
Drug Metab. Dispos
, vol.27
, Issue.2
, pp. 274-280
-
-
Tang, Y.M.1
Chen, G.F.2
Thompson, P.A.3
Lin, D.X.4
Lang, N.P.5
Kadlubar, F.F.6
-
94
-
-
0030008731
-
Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1
-
Shimada, T.; Hayes, C.L.; Yamazaki, H.; Amin, S.; Hecht, S.S.; Guengerich, F.P.; Sutter, T.R. Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1. Cancer Res., 1996, 56(13), 2979-2984.
-
(1996)
Cancer Res
, vol.56
, Issue.13
, pp. 2979-2984
-
-
Shimada, T.1
Hayes, C.L.2
Yamazaki, H.3
Amin, S.4
Hecht, S.S.5
Guengerich, F.P.6
Sutter, T.R.7
-
95
-
-
0035150691
-
In situ hybridization and immunohistochemical analysis of cytochrome P450 1B1 expression in human normal tissues
-
Muskhelishvili, L.; Thompson, P.A.; Kusewitt, D.F.; Wang, C.; Kadlubar, F.F. In situ hybridization and immunohistochemical analysis of cytochrome P450 1B1 expression in human normal tissues. J. Histochem. Cytochem., 2001, 49(2), 229-236.
-
(2001)
J. Histochem. Cytochem
, vol.49
, Issue.2
, pp. 229-236
-
-
Muskhelishvili, L.1
Thompson, P.A.2
Kusewitt, D.F.3
Wang, C.4
Kadlubar, F.F.5
-
96
-
-
41149179260
-
Role of CYP1B1 in glaucoma
-
Vasiliou, V.; Gonzalez, F.J. Role of CYP1B1 in glaucoma. Annu. Rev. Pharmacol. Toxicol., 2008, 48(1), 333-358.
-
(2008)
Annu. Rev. Pharmacol. Toxicol
, vol.48
, Issue.1
, pp. 333-358
-
-
Vasiliou, V.1
Gonzalez, F.J.2
-
97
-
-
0021329662
-
15α). Purification, regioselectivity, stereo specificity, and sex-dependent expression
-
15α). Purification, regioselectivity, stereo specificity, and sex-dependent expression. J. Biol. Chem., 1984, 259(2), 1265-1271.
-
(1984)
J. Biol. Chem
, vol.259
, Issue.2
, pp. 1265-1271
-
-
Harada, N.1
Negishi, M.2
-
98
-
-
0022403303
-
Sexual dimorphism of testosterone 15α-hydroxylase mRNA levels in mouse liver
-
Burkhart, B.A.; Harada, N.; Negishi, M. Sexual dimorphism of testosterone 15α-hydroxylase mRNA levels in mouse liver. J. Biol. Chem., 1985, 260(28), 15357-15361.
-
(1985)
J. Biol. Chem
, vol.260
, Issue.28
, pp. 15357-15361
-
-
Burkhart, B.A.1
Harada, N.2
Negishi, M.3
-
99
-
-
0023893319
-
15α) in liver and kidney of male mice by androgen
-
15α) in liver and kidney of male mice by androgen. J. Biol. Chem., 1988, 263(9), 4166-4171.
-
(1988)
J. Biol. Chem
, vol.263
, Issue.9
, pp. 4166-4171
-
-
Squires, E.J.1
Negishi, M.2
-
100
-
-
0024535917
-
15α gene
-
15α gene. J. Biol. Chem., 1989, 264(11), 6465-6471.
-
(1989)
J. Biol. Chem
, vol.264
, Issue.11
, pp. 6465-6471
-
-
Lindberg, R.1
Burkhart, B.2
Ichikawa, T.3
Negishi, M.4
-
101
-
-
0024976419
-
Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue
-
Lindberg, R.L.P.; Negishi, M. Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue. Nature, 1989, 339(6226), 632-634.
-
(1989)
Nature
, vol.339
, Issue.6226
, pp. 632-634
-
-
Lindberg, R.L.P.1
Negishi, M.2
-
102
-
-
0029789370
-
Expression of CYP2A genes in rodent and human nasal mucosa
-
Su, T.; Sheng, J.J.; Lipinskas, T.W.; Ding, X. Expression of CYP2A genes in rodent and human nasal mucosa. Drug Metab. Dispos., 1996, 24(8), 884-890.
-
(1996)
Drug Metab. Dispos
, vol.24
, Issue.8
, pp. 884-890
-
-
Su, T.1
Sheng, J.J.2
Lipinskas, T.W.3
Ding, X.4
-
103
-
-
3142765079
-
Sexually dimorphic P450 gene expression in liver-specific hepatocyte nuclear factor 4α-deficient mice
-
Wiwi, C.A.; Gupte, M.; Waxman, D.J. Sexually dimorphic P450 gene expression in liver-specific hepatocyte nuclear factor 4α-deficient mice. Mol. Endocrinol., 2004, 18(8), 1975-1987.
-
(2004)
Mol. Endocrinol
, vol.18
, Issue.8
, pp. 1975-1987
-
-
Wiwi, C.A.1
Gupte, M.2
Waxman, D.J.3
-
104
-
-
33749240169
-
Gender-specific induction of cytochrome P450s in nonylphenoltreated FVB/NJ mice
-
Hernandez, J.P.; Chapman, L.M.; Kretschmer, X.C.; Baldwin, W.S. Gender-specific induction of cytochrome P450s in nonylphenoltreated FVB/NJ mice. Toxicol. Appl. Pharmacol., 2006, 216(2), 186-196.
-
(2006)
Toxicol. Appl. Pharmacol
, vol.216
, Issue.2
, pp. 186-196
-
-
Hernandez, J.P.1
Chapman, L.M.2
Kretschmer, X.C.3
Baldwin, W.S.4
-
105
-
-
31044434106
-
Modified expression of cytochrome P450 mRNAs by growth hormone in mouse liver
-
Jarukamjorn, K.; Sakuma, T.; Jaruchotikamol, A.; Ishino, Y.; Oguro, M.; Nemoto, N. Modified expression of cytochrome P450 mRNAs by growth hormone in mouse liver. Toxicology, 2006, 219(1-3), 97-105.
-
(2006)
Toxicology
, vol.219
, Issue.1-3
, pp. 97-105
-
-
Jarukamjorn, K.1
Sakuma, T.2
Jaruchotikamol, A.3
Ishino, Y.4
Oguro, M.5
Nemoto, N.6
-
106
-
-
0345256292
-
Cell-specific expression of CYP2A5 in the mouse respiratory tract: Effects of olfactory toxicants
-
Piras, E.; Franzén, A.; Fernández, E.L.; Bergström, U.; Raffalli-Mathieu, F.; Lang, M.; Brittebo, E.B. Cell-specific expression of CYP2A5 in the mouse respiratory tract: effects of olfactory toxicants. J. Histochem. Cytochem., 2003, 51(11), 1545-1555.
-
(2003)
J. Histochem. Cytochem
, vol.51
, Issue.11
, pp. 1545-1555
-
-
Piras, E.1
Franzén, A.2
Fernández, E.L.3
Bergström, U.4
Raffalli-Mathieu, F.5
Lang, M.6
Brittebo, E.B.7
-
107
-
-
27744555294
-
Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone-induced mouse lung adenomas
-
Miyazaki, M.;, Yamazaki, H.; Takeuchi, H.; Saoo, K.; Yokohira, M.; Masumura, K.; Nohmi, T.; Funae, Y.; Imaida, K.; Kamataki, T. Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone-induced mouse lung adenomas. Carcinogenesis, 2005, 26(11), 1947-1955.
-
(2005)
Carcinogenesis
, vol.26
, Issue.11
, pp. 1947-1955
-
-
Miyazaki, M.1
Yamazaki, H.2
Takeuchi, H.3
Saoo, K.4
Yokohira, M.5
Masumura, K.6
Nohmi, T.7
Funae, Y.8
Imaida, K.9
Kamataki, T.10
-
108
-
-
0031808169
-
-
Powell, P.K.; Wolf, I.; Jin, R.; Lasker, J.M. Metabolism of arachidonic acid to 20-hydroxy-5,8,11,14-eicosatetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11. J. Pharmacol. Exp. Ther., 1998, 285(3), 1327-1336.
-
Powell, P.K.; Wolf, I.; Jin, R.; Lasker, J.M. Metabolism of arachidonic acid to 20-hydroxy-5,8,11,14-eicosatetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11. J. Pharmacol. Exp. Ther., 1998, 285(3), 1327-1336.
-
-
-
-
110
-
-
0024337369
-
Mouse liver phenobarbital-inducible P450 system: Purification, characterization, and differential inducibility of four cytochrome P450 isozymes from D2 mouse
-
Honkakoski, P.; Lang, M.A. Mouse liver phenobarbital-inducible P450 system: purification, characterization, and differential inducibility of four cytochrome P450 isozymes from D2 mouse. Arch. Biochem. Biophys., 1989, 273(1), 42-57.
-
(1989)
Arch. Biochem. Biophys
, vol.273
, Issue.1
, pp. 42-57
-
-
Honkakoski, P.1
Lang, M.A.2
-
111
-
-
0024317616
-
Purification and characterization of a mouse liver cytochrome P-450 induced by cannabidiol
-
Bornheim, L.M.; Correia, M.A. Purification and characterization of a mouse liver cytochrome P-450 induced by cannabidiol. Mol. Pharmacol., 1989, 36(3), 377-383.
-
(1989)
Mol. Pharmacol
, vol.36
, Issue.3
, pp. 377-383
-
-
Bornheim, L.M.1
Correia, M.A.2
-
112
-
-
0026672926
-
Regulation of the mouse liver cytochrome P450 2B subfamily by sex hormones and phenobarbital
-
Honkakoski, P.; Kojo, A.; Lang, M.A. Regulation of the mouse liver cytochrome P450 2B subfamily by sex hormones and phenobarbital. Biochem. J., 1992, 285(3), 979-983.
-
(1992)
Biochem. J
, vol.285
, Issue.3
, pp. 979-983
-
-
Honkakoski, P.1
Kojo, A.2
Lang, M.A.3
-
113
-
-
0029070983
-
Glucocorticoid and sex hormones as activating or modulating factors for expression of Cyp2b-9 and Cyp2b-10 in the mouse liver and hepatocytes
-
Nemoto, N.; Sakurai, J. Glucocorticoid and sex hormones as activating or modulating factors for expression of Cyp2b-9 and Cyp2b-10 in the mouse liver and hepatocytes. Arch. Biochem. Biophys., 1995, 319(1), 286-292.
-
(1995)
Arch. Biochem. Biophys
, vol.319
, Issue.1
, pp. 286-292
-
-
Nemoto, N.1
Sakurai, J.2
-
114
-
-
0033198790
-
Different regulation of the expression of mouse hepatic cytochrome P450 2B enzymes by glucocorticoid and phenobarbital
-
Jarukamjorn, K.; Sakuma, T.; Miyaura, J.I.; Nemoto, N. Different regulation of the expression of mouse hepatic cytochrome P450 2B enzymes by glucocorticoid and phenobarbital. Arch. Biochem. Biophys., 1999, 369(1), 89-99.
-
(1999)
Arch. Biochem. Biophys
, vol.369
, Issue.1
, pp. 89-99
-
-
Jarukamjorn, K.1
Sakuma, T.2
Miyaura, J.I.3
Nemoto, N.4
-
115
-
-
0035879967
-
Sex-associated expression of mouse hepatic and renal CYP2B enzymes by glucocorticoid hormones
-
Jarukamjorn, K.; Sakuma, T.; Yamamoto, M.; Ohara, A.; Nemoto, N. Sex-associated expression of mouse hepatic and renal CYP2B enzymes by glucocorticoid hormones. Biochem. Pharmacol., 2001, 62(2), 161-169.
-
(2001)
Biochem. Pharmacol
, vol.62
, Issue.2
, pp. 161-169
-
-
Jarukamjorn, K.1
Sakuma, T.2
Yamamoto, M.3
Ohara, A.4
Nemoto, N.5
-
116
-
-
0033610838
-
Differentiating keratinocytes express a novel cytochrome P450 enzyme, CYP2B19, having arachidonate monooxygenase activity
-
Keeney, D.S.; Skinner, C.; Travers, J.B.; Capdevila, J.H.; Nanney, L.B.; King, L.E.Jr.; Waterman, M.R. Differentiating keratinocytes express a novel cytochrome P450 enzyme, CYP2B19, having arachidonate monooxygenase activity. J. Biol. Chem., 1998, 273(48), 32071-32079.
-
(1998)
J. Biol. Chem
, vol.273
, Issue.48
, pp. 32071-32079
-
-
Keeney, D.S.1
Skinner, C.2
Travers, J.B.3
Capdevila, J.H.4
Nanney, L.B.5
King Jr, L.E.6
Waterman, M.R.7
-
117
-
-
0032167962
-
Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid
-
Luo, G.; Zeldin, D.C.; Blaisdell, J.A.; Hodgson, E.; Goldstein, J.A. Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid. Arch. Biochem. Biophys., 1998, 357(1), 45-57.
-
(1998)
Arch. Biochem. Biophys
, vol.357
, Issue.1
, pp. 45-57
-
-
Luo, G.1
Zeldin, D.C.2
Blaisdell, J.A.3
Hodgson, E.4
Goldstein, J.A.5
-
118
-
-
0033916007
-
CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract
-
Tsao, C.C.; Foley, J.; Coulter, S.J.; Maronpot, R.; Zeldin, D.C.; Goldstein, J.A. CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract. Mol. Pharmacol., 2000, 58(2), 279-287.
-
(2000)
Mol. Pharmacol
, vol.58
, Issue.2
, pp. 279-287
-
-
Tsao, C.C.1
Foley, J.2
Coulter, S.J.3
Maronpot, R.4
Zeldin, D.C.5
Goldstein, J.A.6
-
119
-
-
0034802185
-
Identification and localization of five CYP2Cs in murine extrahepatic tissues and their metabolism of arachidonic acid to regio- and stereoselective products
-
Tsao, C.C.; Coulter, S.J.; Chien, A.; Luo, G.; Clayton, N.P.; Maronpot, R.; Goldstein, J.A.; Zeldin, D.C. Identification and localization of five CYP2Cs in murine extrahepatic tissues and their metabolism of arachidonic acid to regio- and stereoselective products. J. Pharmacol. Exp. Ther., 2001, 299(1), 39-47.
-
(2001)
J. Pharmacol. Exp. Ther
, vol.299
, Issue.1
, pp. 39-47
-
-
Tsao, C.C.1
Coulter, S.J.2
Chien, A.3
Luo, G.4
Clayton, N.P.5
Maronpot, R.6
Goldstein, J.A.7
Zeldin, D.C.8
-
120
-
-
2442657802
-
The constitutive active/androstane receptor regulates phenytoin induction of Cyp2c29
-
Jackson, J.P.; Ferguson, S.S.; Moore, R.; Negishi, M.; Goldstein, J.A. The constitutive active/androstane receptor regulates phenytoin induction of Cyp2c29. Mol. Pharmacol., 2004, 65(6), 1397-1404.
-
(2004)
Mol. Pharmacol
, vol.65
, Issue.6
, pp. 1397-1404
-
-
Jackson, J.P.1
Ferguson, S.S.2
Moore, R.3
Negishi, M.4
Goldstein, J.A.5
-
121
-
-
0942265563
-
Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice
-
Andreola, F.; Hayhurst, G.P.; Luo, G.; Ferguson, S.S.; Gonzalez, F.J.; Goldstein, J.A.; De Luca, L.M. Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice. J. Biol. Chem., 2004, 279(5), 3434-3438.
-
(2004)
J. Biol. Chem
, vol.279
, Issue.5
, pp. 3434-3438
-
-
Andreola, F.1
Hayhurst, G.P.2
Luo, G.3
Ferguson, S.S.4
Gonzalez, F.J.5
Goldstein, J.A.6
De Luca, L.M.7
-
122
-
-
2142695293
-
Cloning, expression, and characterization of three new mouse cytochrome P450 enzymes and partial characterization of their fatty acid oxidation activities
-
Wang, H.; Zhao, Y.; Bradbury, J.A.; Graves, J.P.; Foley, J.; Blaisdell, J.A.; Goldstein, J.A.; Zeldin, D.C. Cloning, expression, and characterization of three new mouse cytochrome P450 enzymes and partial characterization of their fatty acid oxidation activities. Mol. Pharmacol., 2004, 65(5), 1148-1158.
-
(2004)
Mol. Pharmacol
, vol.65
, Issue.5
, pp. 1148-1158
-
-
Wang, H.1
Zhao, Y.2
Bradbury, J.A.3
Graves, J.P.4
Foley, J.5
Blaisdell, J.A.6
Goldstein, J.A.7
Zeldin, D.C.8
-
123
-
-
4243182600
-
CYP2C44, a new murine CYP2C that metabolizes arachidonic acid to unique stereospecific products
-
DeLozier, T.C.; Tsao, C.C.; Coulter, S.J.; Foley, J.; Bradbury, J.A.; Zeldin, D.C.; Goldstein, J.A. CYP2C44, a new murine CYP2C that metabolizes arachidonic acid to unique stereospecific products. J. Pharmacol. Exp. Ther., 2004, 310(3), 845-854.
-
(2004)
J. Pharmacol. Exp. Ther
, vol.310
, Issue.3
, pp. 845-854
-
-
DeLozier, T.C.1
Tsao, C.C.2
Coulter, S.J.3
Foley, J.4
Bradbury, J.A.5
Zeldin, D.C.6
Goldstein, J.A.7
-
124
-
-
33645809139
-
The human intestinal cytochrome P450 "pie
-
Paine, M.F.; Hart, H.L.; Ludington, S.S.; Haining, R.L.; Rettie, A.E.; Zeldin, D.C. The human intestinal cytochrome P450 "pie". Drug Metab. Dispos., 2006, 34(5), 880-886.
-
(2006)
Drug Metab. Dispos
, vol.34
, Issue.5
, pp. 880-886
-
-
Paine, M.F.1
Hart, H.L.2
Ludington, S.S.3
Haining, R.L.4
Rettie, A.E.5
Zeldin, D.C.6
-
126
-
-
0024520426
-
16α) in mice. Organization, differential regulation, and chromosome localization
-
16α) in mice. Organization, differential regulation, and chromosome localization. J. Biol. Chem., 1989, 264(5), 2920-2927.
-
(1989)
J. Biol. Chem
, vol.264
, Issue.5
, pp. 2920-2927
-
-
Wong, G.1
Itakura, T.2
Kawajiri, K.3
Skow, L.4
Negishi, M.5
-
127
-
-
70349569532
-
Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers
-
Režen, T.; Tamasi, V.; Lövgren-Sandblom, A.; Björkhem, I.; Meyer, U.A.; Rozman, D. Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers. BMC Genomics, 2009, 10(1), 384-398.
-
(2009)
BMC Genomics
, vol.10
, Issue.1
, pp. 384-398
-
-
Režen, T.1
Tamasi, V.2
Lövgren-Sandblom, A.3
Björkhem, I.4
Meyer, U.A.5
Rozman, D.6
-
128
-
-
0034664679
-
Characterization of Cyp2d22, a novel cytochrome P450 expressed in mouse mammary cells
-
Blume, N.; Leonard, J.; Xu, Z.J.; Watanabe, O.; Remotti, H.; Fishman, J. Characterization of Cyp2d22, a novel cytochrome P450 expressed in mouse mammary cells. Arch. Biochem. Biophys., 2000, 381(2), 191-204.
-
(2000)
Arch. Biochem. Biophys
, vol.381
, Issue.2
, pp. 191-204
-
-
Blume, N.1
Leonard, J.2
Xu, Z.J.3
Watanabe, O.4
Remotti, H.5
Fishman, J.6
-
129
-
-
0031000628
-
The ability of C/EBPβ but not C/EBPα to synergize with an Sp1 protein is specified by the leucine zipper and activation domain
-
Lee, Y.H.; Williams, S.C.; Baer, M.; Sterneck, E.; Gonzalez, F.J.; Johnson, P.F. The ability of C/EBPβ but not C/EBPα to synergize with an Sp1 protein is specified by the leucine zipper and activation domain. Mol. Cell. Biol., 1997, 17(4), 2038-2047.
-
(1997)
Mol. Cell. Biol
, vol.17
, Issue.4
, pp. 2038-2047
-
-
Lee, Y.H.1
Williams, S.C.2
Baer, M.3
Sterneck, E.4
Gonzalez, F.J.5
Johnson, P.F.6
-
130
-
-
0028366090
-
Multiple cytochrome P450 isozymes in murine skin: Induction of P450 1A, 2B, 2E, and 3A by dexamethasone
-
Jugert, F.K.; Agarwal, R.; Kuhn, A.; Bickers, D.R.; Merk, H.F.; Mukhtar, H. Multiple cytochrome P450 isozymes in murine skin: induction of P450 1A, 2B, 2E, and 3A by dexamethasone. J. Invest. Dermatol., 1994, 102(6), 970-975.
-
(1994)
J. Invest. Dermatol
, vol.102
, Issue.6
, pp. 970-975
-
-
Jugert, F.K.1
Agarwal, R.2
Kuhn, A.3
Bickers, D.R.4
Merk, H.F.5
Mukhtar, H.6
-
131
-
-
0037497148
-
Expression and activity of cytochromes P450 2E1, 2A, and 2B in the mouse ovary: The effect of 4-vinylcyclohexene and its diepoxide metabolite
-
Cannady, E.A.; Dyer, C.A.; Christian, P.J.; Sipes, I.G.; Hoyer, P.B. Expression and activity of cytochromes P450 2E1, 2A, and 2B in the mouse ovary: the effect of 4-vinylcyclohexene and its diepoxide metabolite. Toxicol. Sci., 2003, 73(2), 423-430.
-
(2003)
Toxicol. Sci
, vol.73
, Issue.2
, pp. 423-430
-
-
Cannady, E.A.1
Dyer, C.A.2
Christian, P.J.3
Sipes, I.G.4
Hoyer, P.B.5
-
132
-
-
0031590422
-
Suppression of cytochrome P450 Cyp2f2 mRNA levels in mice by the peroxisome proliferator diethylhexylphthalate
-
Ye, X.; Lu, L.; Gill, S.S. Suppression of cytochrome P450 Cyp2f2 mRNA levels in mice by the peroxisome proliferator diethylhexylphthalate. Biochem. Biophys. Res. Commun., 1997, 239(3), 660-665.
-
(1997)
Biochem. Biophys. Res. Commun
, vol.239
, Issue.3
, pp. 660-665
-
-
Ye, X.1
Lu, L.2
Gill, S.S.3
-
133
-
-
1642377628
-
Comparison of pulmonary/nasal CYP2F expression levels in rodents and rhesus macaque
-
Baldwin, R.M.; Jewell, W.T.; Fanucchi, M.V.; Plopper, C.G.; Buckpitt, A.R. Comparison of pulmonary/nasal CYP2F expression levels in rodents and rhesus macaque. J. Pharmacol. Exp. Ther., 2004, 309(1), 127-136.
-
(2004)
J. Pharmacol. Exp. Ther
, vol.309
, Issue.1
, pp. 127-136
-
-
Baldwin, R.M.1
Jewell, W.T.2
Fanucchi, M.V.3
Plopper, C.G.4
Buckpitt, A.R.5
-
134
-
-
0032990708
-
Specific dehydrogenation of 3-methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells
-
Lanza, D.L.; Code, E.; Crespi, C.L.; Gonzalez, F.J.; Yost, G.S. Specific dehydrogenation of 3-methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells. Drug Metab. Dispos., 1999, 27(7), 798-803.
-
(1999)
Drug Metab. Dispos
, vol.27
, Issue.7
, pp. 798-803
-
-
Lanza, D.L.1
Code, E.2
Crespi, C.L.3
Gonzalez, F.J.4
Yost, G.S.5
-
135
-
-
0036793580
-
Testosterone, cytochrome P450, and cardiac hypertrophy
-
Thum, T.; Borlak, J. Testosterone, cytochrome P450, and cardiac hypertrophy. FASEB J., 2002, 16(12), 1537-1549.
-
(2002)
FASEB J
, vol.16
, Issue.12
, pp. 1537-1549
-
-
Thum, T.1
Borlak, J.2
-
136
-
-
0031569808
-
cDNA cloning, heterologous expression, and characterization of mouse CYP2G1, an olfactory-specific steroid hydroxylase
-
Hua, Z.; Zhang, Q.Y.; Su, T.; Lipinskas, T.W.; Ding, X. cDNA cloning, heterologous expression, and characterization of mouse CYP2G1, an olfactory-specific steroid hydroxylase. Arch. Biochem. Biophys., 1997, 340(2), 208-214.
-
(1997)
Arch. Biochem. Biophys
, vol.340
, Issue.2
, pp. 208-214
-
-
Hua, Z.1
Zhang, Q.Y.2
Su, T.3
Lipinskas, T.W.4
Ding, X.5
-
137
-
-
0033009103
-
P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues
-
Scarborough, P.E.; Ma, J.; Qu, W.; Zeldin, D.C. P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues. Drug Metab. Rev., 1999, 31(1), 205-234.
-
(1999)
Drug Metab. Rev
, vol.31
, Issue.1
, pp. 205-234
-
-
Scarborough, P.E.1
Ma, J.2
Qu, W.3
Zeldin, D.C.4
-
138
-
-
0033580922
-
Molecular cloning, enzymatic characterization, developmental expression, and cellular localization of a mouse cytochrome P450 highly expressed in kidney
-
Ma, J.; Qu, W.; Scarborough, P.E.; Tomer, K.B.; Moomaw, C.R.; Maronpot, R.; Davis, L.S.; Breyer, M.D.; Zeldin, D.C. Molecular cloning, enzymatic characterization, developmental expression, and cellular localization of a mouse cytochrome P450 highly expressed in kidney. J. Biol. Chem., 1999, 274(25), 17777-17788.
-
(1999)
J. Biol. Chem
, vol.274
, Issue.25
, pp. 17777-17788
-
-
Ma, J.1
Qu, W.2
Scarborough, P.E.3
Tomer, K.B.4
Moomaw, C.R.5
Maronpot, R.6
Davis, L.S.7
Breyer, M.D.8
Zeldin, D.C.9
-
139
-
-
0033786280
-
Induction of mouse CYP2J by pyrazole in the eye, kidney, liver, lung, olfactory mucosa, and small intestine, but not in the heart
-
Xie, Q.; Zhang, Q.Y.; Zhang, Y.; Su, T.; Gu, J.; Kaminsky, L.S.; Ding, X. Induction of mouse CYP2J by pyrazole in the eye, kidney, liver, lung, olfactory mucosa, and small intestine, but not in the heart. Drug Metab. Dispos., 2000, 28(11), 1311-1316.
-
(2000)
Drug Metab. Dispos
, vol.28
, Issue.11
, pp. 1311-1316
-
-
Xie, Q.1
Zhang, Q.Y.2
Zhang, Y.3
Su, T.4
Gu, J.5
Kaminsky, L.S.6
Ding, X.7
-
140
-
-
0035816583
-
Cytochrome P450 CYP2J9, a new mouse arachidonic acid ω-1 hydroxylase predominantly expressed in brain
-
Qu, W.; Bradbury, J.A.; Tsao, C.C.; Maronpot, R.; Harry, G.J.; Parker, C.E.; Davis, L.S.; Breyer, M.D.; Waalkes, M.P.; Falck, J.R.; Chen, J.; Rosenberg, R.L.; Zeldin, D.C. Cytochrome P450 CYP2J9, a new mouse arachidonic acid ω-1 hydroxylase predominantly expressed in brain. J. Biol. Chem., 2001, 276(27), 25467-25479.
-
(2001)
J. Biol. Chem
, vol.276
, Issue.27
, pp. 25467-25479
-
-
Qu, W.1
Bradbury, J.A.2
Tsao, C.C.3
Maronpot, R.4
Harry, G.J.5
Parker, C.E.6
Davis, L.S.7
Breyer, M.D.8
Waalkes, M.P.9
Falck, J.R.10
Chen, J.11
Rosenberg, R.L.12
Zeldin, D.C.13
-
141
-
-
0030063499
-
Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart
-
Wu, S.; Moomaw, C.R.; Tomer, K.B.; Falck, J.R.; Zeldin, D.C. Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart. J. Biol. Chem., 1996, 271(7), 3460-3468.
-
(1996)
J. Biol. Chem
, vol.271
, Issue.7
, pp. 3460-3468
-
-
Wu, S.1
Moomaw, C.R.2
Tomer, K.B.3
Falck, J.R.4
Zeldin, D.C.5
-
142
-
-
33646586642
-
Effects of the differentiated keratinocyte phenotype on expression levels of CYP1-4 family genes in human skin cells
-
Du, L.; Neis, M.M.; Ladd, P.A.; Lanza, D.L.; Yost, G.S.; Keeney, D.S. Effects of the differentiated keratinocyte phenotype on expression levels of CYP1-4 family genes in human skin cells. Toxicol. Appl. Pharmacol., 2006, 213(2), 135-144.
-
(2006)
Toxicol. Appl. Pharmacol
, vol.213
, Issue.2
, pp. 135-144
-
-
Du, L.1
Neis, M.M.2
Ladd, P.A.3
Lanza, D.L.4
Yost, G.S.5
Keeney, D.S.6
-
143
-
-
0141732321
-
Deorphanization of cytochrome P450 2R1: A microsomal vitamin D 25-hydroxylase
-
Cheng, J.B.; Motola, D.L.; Mangelsdorf, D.J.; Russell, D.W. Deorphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxylase. J. Biol. Chem., 2003, 278(39), 38084-38093.
-
(2003)
J. Biol. Chem
, vol.278
, Issue.39
, pp. 38084-38093
-
-
Cheng, J.B.1
Motola, D.L.2
Mangelsdorf, D.J.3
Russell, D.W.4
-
144
-
-
24644473254
-
CYP2S1: A short review
-
Saarikoski, S.T.; Rivera, S.P.; Hankinson, O.; Husgafvel-Pursiainen, K. CYP2S1: a short review. Toxicol. Appl. Pharmacol., 2005, 207(2), S62-S69.
-
(2005)
Toxicol. Appl. Pharmacol
, vol.207
, Issue.2
-
-
Saarikoski, S.T.1
Rivera, S.P.2
Hankinson, O.3
Husgafvel-Pursiainen, K.4
-
145
-
-
67649253119
-
Characterization and expression of extrahepatic CYP2S1
-
Deb, S.; Bandiera, S.M. Characterization and expression of extrahepatic CYP2S1. Expert Opin. Drug Metab. Toxicol., 2009, 5(4), 367-380.
-
(2009)
Expert Opin. Drug Metab. Toxicol
, vol.5
, Issue.4
, pp. 367-380
-
-
Deb, S.1
Bandiera, S.M.2
-
146
-
-
10744226053
-
CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes ω- and (ω-1)-hydroxylation of fatty acids
-
Chuang, S.S.; Helvig, C.; Taimi, M.; Ramshaw, H.A.; Collop, A.H.; Amad, M.; White, J.A.; Petkovich, M.; Jones, G.; Korczak, B. CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes ω- and (ω-1)-hydroxylation of fatty acids. J. Biol. Chem., 2004, 279(8), 6305-6314.
-
(2004)
J. Biol. Chem
, vol.279
, Issue.8
, pp. 6305-6314
-
-
Chuang, S.S.1
Helvig, C.2
Taimi, M.3
Ramshaw, H.A.4
Collop, A.H.5
Amad, M.6
White, J.A.7
Petkovich, M.8
Jones, G.9
Korczak, B.10
-
147
-
-
1242272848
-
Characterization and tissue distribution of a novel human cytochrome P450-CYP2U1
-
Karlgren, M.; Backlund, M.; Johansson, I.; Oscarson, M.; Ingelman-Sundberg, M. Characterization and tissue distribution of a novel human cytochrome P450-CYP2U1. Biochem. Biophys. Res. Commun., 2004, 315(3), 679-685.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.315
, Issue.3
, pp. 679-685
-
-
Karlgren, M.1
Backlund, M.2
Johansson, I.3
Oscarson, M.4
Ingelman-Sundberg, M.5
-
148
-
-
31444443707
-
-
Karlgren, M.; Gomez, A.; Stark, K.; Svärd, J.; Rodriguez-Antona, C.; Oliw, E.; Bernal, M.L.; Ramón y Cajal, S.; Johansson, I.; Ingelman-Sundberg, M. Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1. Biochem. Biophys. Res. Commun., 2006, 341(2), 451-458.
-
Karlgren, M.; Gomez, A.; Stark, K.; Svärd, J.; Rodriguez-Antona, C.; Oliw, E.; Bernal, M.L.; Ramón y Cajal, S.; Johansson, I.; Ingelman-Sundberg, M. Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1. Biochem. Biophys. Res. Commun., 2006, 341(2), 451-458.
-
-
-
-
149
-
-
0025050635
-
Selective inactivation of mouse liver cytochrome P-450IIIA by cannabidiol
-
Bornheim, L.M.; Correia, M.A. Selective inactivation of mouse liver cytochrome P-450IIIA by cannabidiol. Mol. Pharmacol., 1990, 38(3), 319-326.
-
(1990)
Mol. Pharmacol
, vol.38
, Issue.3
, pp. 319-326
-
-
Bornheim, L.M.1
Correia, M.A.2
-
150
-
-
0031569864
-
Mouse cytochrome P450 (Cyp3a11): Predominant expression in liver and capacity to activate aflatoxin B1
-
Yanagimoto, T.; Itoh, S.; Sawada, M.; Kamataki, T. Mouse cytochrome P450 (Cyp3a11): predominant expression in liver and capacity to activate aflatoxin B1. Arch. Biochem. Biophys., 1997, 340(2), 215-218.
-
(1997)
Arch. Biochem. Biophys
, vol.340
, Issue.2
, pp. 215-218
-
-
Yanagimoto, T.1
Itoh, S.2
Sawada, M.3
Kamataki, T.4
-
151
-
-
0034192256
-
A novel female-specific member of the CYP3A gene subfamily in the mouse liver
-
Sakuma, T.; Takai, M.; Endo, Y.; Kuroiwa, M.; Ôhara, A.; Jarukamjorn, K.; Honma, R.; Nemoto, N. A novel female-specific member of the CYP3A gene subfamily in the mouse liver. Arch. Biochem. Biophys., 2000, 377(1), 153-162.
-
(2000)
Arch. Biochem. Biophys
, vol.377
, Issue.1
, pp. 153-162
-
-
Sakuma, T.1
Takai, M.2
Endo, Y.3
Kuroiwa, M.4
Ôhara, A.5
Jarukamjorn, K.6
Honma, R.7
Nemoto, N.8
-
152
-
-
33646799507
-
Comparison of mouse and rat cytochrome P450-mediated metabolism in liver and intestine
-
Martignoni, M.; Groothuis, G.; de Kanter, R. Comparison of mouse and rat cytochrome P450-mediated metabolism in liver and intestine. Drug Metab. Dispos., 2006, 34(6), 1047-1054.
-
(2006)
Drug Metab. Dispos
, vol.34
, Issue.6
, pp. 1047-1054
-
-
Martignoni, M.1
Groothuis, G.2
de Kanter, R.3
-
153
-
-
0027999639
-
Molecular cloning and functional expression of a mouse cytochrome P-450 (Cyp3a-13): Examination of Cyp3a-13 enzyme to activate aflatoxin B1 (AFB1)
-
Yanagimoto, T.; Itoh, S.; Sawada, M.; Hashimoto, H.; Kamataki, T. Molecular cloning and functional expression of a mouse cytochrome P-450 (Cyp3a-13): examination of Cyp3a-13 enzyme to activate aflatoxin B1 (AFB1). Biochim. Biophys. Acta, 1994, 1201(3), 405-410.
-
(1994)
Biochim. Biophys. Acta
, vol.1201
, Issue.3
, pp. 405-410
-
-
Yanagimoto, T.1
Itoh, S.2
Sawada, M.3
Hashimoto, H.4
Kamataki, T.5
-
154
-
-
0028556593
-
A novel form of mouse cytochrome P450 3A (Cyp3a-16). Its cDNA cloning and expression in fetal liver
-
Itoh, S.; Satoh, M.; Abe, Y.; Hashimoto, H.; Yanagimoto, T.; Kamataki, T. A novel form of mouse cytochrome P450 3A (Cyp3a-16). Its cDNA cloning and expression in fetal liver. Eur. J. Biochem., 1994, 226(3), 877-882.
-
(1994)
Eur. J. Biochem
, vol.226
, Issue.3
, pp. 877-882
-
-
Itoh, S.1
Satoh, M.2
Abe, Y.3
Hashimoto, H.4
Yanagimoto, T.5
Kamataki, T.6
-
155
-
-
0035048387
-
Cloning, sequencing, heterologous expression, and characterization of murine cytochrome P450 3a25*(Cyp3a25), a testosterone 6β-hydroxylase
-
Dai, D.; Bai, R.; Hodgson, E.; Rose, R.L. Cloning, sequencing, heterologous expression, and characterization of murine cytochrome P450 3a25*(Cyp3a25), a testosterone 6β-hydroxylase. J. Biochem. Mol. Toxicol., 2001, 15(2), 90-99.
-
(2001)
J. Biochem. Mol. Toxicol
, vol.15
, Issue.2
, pp. 90-99
-
-
Dai, D.1
Bai, R.2
Hodgson, E.3
Rose, R.L.4
-
156
-
-
0037102517
-
Regulation of the expression of two female-predominant CYP3A mRNAs (CYP3A41 and CYP3A44) in mouse liver by sex and growth hormones
-
Sakuma, T.; Endo, Y.; Mashino, M.; Kuroiwa, M.; Ohara, A.; Jarukamjorn, K.; Nemoto, N. Regulation of the expression of two female-predominant CYP3A mRNAs (CYP3A41 and CYP3A44) in mouse liver by sex and growth hormones. Arch. Biochem. Biophys., 2002, 404(2), 234-242.
-
(2002)
Arch. Biochem. Biophys
, vol.404
, Issue.2
, pp. 234-242
-
-
Sakuma, T.1
Endo, Y.2
Mashino, M.3
Kuroiwa, M.4
Ohara, A.5
Jarukamjorn, K.6
Nemoto, N.7
-
157
-
-
77649124246
-
Dietary cholic acid alters hepatic cytochrome P450 enzyme expression in SPGP knockout mice
-
Abstract 290
-
Hrycay, E.G.; Tai, J.K.; Forrest, D.N.; Wang, R.; Ling, V.; Bandiera, S.M. Dietary cholic acid alters hepatic cytochrome P450 enzyme expression in SPGP knockout mice. Drug Metab. Rev., 2004, 36(Suppl. 1), Abstract 290.
-
(2004)
Drug Metab. Rev
, vol.36
, Issue.SUPPL. 1
-
-
Hrycay, E.G.1
Tai, J.K.2
Forrest, D.N.3
Wang, R.4
Ling, V.5
Bandiera, S.M.6
-
158
-
-
0027304729
-
Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs
-
Bell, D.R.; Plant, N.J.; Rider, C.G.; Na, L.; Brown, S.; Ateitalla, I.; Acharya, S.K.; Davies, M.H.; Elias, E.; Jenkins, N.A.; Gilbert, D.J.; Copeland, N.G.; Elcombe, C.R. Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs. Biochem. J., 1993, 294(1), 173-180.
-
(1993)
Biochem. J
, vol.294
, Issue.1
, pp. 173-180
-
-
Bell, D.R.1
Plant, N.J.2
Rider, C.G.3
Na, L.4
Brown, S.5
Ateitalla, I.6
Acharya, S.K.7
Davies, M.H.8
Elias, E.9
Jenkins, N.A.10
Gilbert, D.J.11
Copeland, N.G.12
Elcombe, C.R.13
-
159
-
-
0030849408
-
A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans
-
Heng, Y.M.; Kuo, C.W.S.; Jones, P.S.; Savory, R.; Schulz, R.M.; Tomlinson, S.R.; Gray, T.J.B.; Bell, D.R. A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans. Biochem. J., 1997, 325(3), 741-749.
-
(1997)
Biochem. J
, vol.325
, Issue.3
, pp. 741-749
-
-
Heng, Y.M.1
Kuo, C.W.S.2
Jones, P.S.3
Savory, R.4
Schulz, R.M.5
Tomlinson, S.R.6
Gray, T.J.B.7
Bell, D.R.8
-
160
-
-
0037215134
-
Distribution of cytochrome P-450 4A and 4F isoforms along the nephron in mice
-
Stec, D.E.; Flasch, A.; Roman, R.J.; White, J.A. Distribution of cytochrome P-450 4A and 4F isoforms along the nephron in mice. Am. J. Physiol. Renal Physiol., 2003, 284(1), F95-F102.
-
(2003)
Am. J. Physiol. Renal Physiol
, vol.284
, Issue.1
-
-
Stec, D.E.1
Flasch, A.2
Roman, R.J.3
White, J.A.4
-
161
-
-
1842866273
-
Expression of cytochrome P450 4A mRNA in mouse lung: Effect of clofibrate and interleukin-1β
-
Le Bouquin, R.; Lugnier, R.; Frossard, A.; Pons, F. Expression of cytochrome P450 4A mRNA in mouse lung: effect of clofibrate and interleukin-1β. Fundam. Clin. Pharmacol., 2004, 18(2), 181-186.
-
(2004)
Fundam. Clin. Pharmacol
, vol.18
, Issue.2
, pp. 181-186
-
-
Le Bouquin, R.1
Lugnier, R.2
Frossard, A.3
Pons, F.4
-
162
-
-
0016837241
-
Sodium periodate, sodium chlorite, organic hydroperoxides, and H2O2 as hydroxylating agents in steroid hydroxylation reactions catalyzed by partially purified cytochrome P-450
-
Hrycay, E.G.; Gustafsson, J.Å.; Ingelman-Sundberg, M.; Ernster, L. Sodium periodate, sodium chlorite, organic hydroperoxides, and H2O2 as hydroxylating agents in steroid hydroxylation reactions catalyzed by partially purified cytochrome P-450. Biochem. Biophys. Res. Commun., 1975, 66(1), 209-216.
-
(1975)
Biochem. Biophys. Res. Commun
, vol.66
, Issue.1
, pp. 209-216
-
-
Hrycay, E.G.1
Gustafsson, J.A.2
Ingelman-Sundberg, M.3
Ernster, L.4
-
163
-
-
34147168221
-
Mouse Cyp4a isoforms: Enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation
-
Muller, D.N.; Schmidt, C.; Barbosa-Sicard, E.; Wellner, M.; Gross, V.; Hercule, H.; Markovic, M.; Honeck, H.; Luft, F.C.; Schunck, W.H. Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation. Biochem. J., 2007, 403(1), 109-118.
-
(2007)
Biochem. J
, vol.403
, Issue.1
, pp. 109-118
-
-
Muller, D.N.1
Schmidt, C.2
Barbosa-Sicard, E.3
Wellner, M.4
Gross, V.5
Hercule, H.6
Markovic, M.7
Honeck, H.8
Luft, F.C.9
Schunck, W.H.10
-
164
-
-
0027125989
-
2-terminal amino acid sequences of human and rat kidney fatty acid ω-hydroxylases
-
2-terminal amino acid sequences of human and rat kidney fatty acid ω-hydroxylases. Biochim. Biophys. Acta, 1992, 1123(2), 156-162.
-
(1992)
Biochim. Biophys. Acta
, vol.1123
, Issue.2
, pp. 156-162
-
-
Kawashima, H.1
Kusunose, E.2
Kubota, I.3
Maekawa, M.4
Kusunose, M.5
-
165
-
-
0027931396
-
Purification and cDNA cloning of human liver CYP4A fatty acid ω-hydroxylase
-
Kawashima, H.; Kusunose, E.; Kikuta, Y.; Kinoshita, H.; Tanaka, S.; Yamamoto, S.; Kishimoto, T.; Kusunose, M. Purification and cDNA cloning of human liver CYP4A fatty acid ω-hydroxylase. J. Biochem., 1994, 116(1), 74-80.
-
(1994)
J. Biochem
, vol.116
, Issue.1
, pp. 74-80
-
-
Kawashima, H.1
Kusunose, E.2
Kikuta, Y.3
Kinoshita, H.4
Tanaka, S.5
Yamamoto, S.6
Kishimoto, T.7
Kusunose, M.8
-
166
-
-
0030297422
-
Identification of CYP4A11 as the major lauric acid ω-hydroxylase in human liver microsomes
-
Powell, P.K.; Wolf, I.; Lasker, J.M. Identification of CYP4A11 as the major lauric acid ω-hydroxylase in human liver microsomes. Arch. Biochem. Biophys., 1996, 335(1), 219-226.
-
(1996)
Arch. Biochem. Biophys
, vol.335
, Issue.1
, pp. 219-226
-
-
Powell, P.K.1
Wolf, I.2
Lasker, J.M.3
-
167
-
-
0035166533
-
Cytochrome P450 4A11 expression in human keratinocytes: Effects of ultraviolet irradiation
-
Gonzalez, M.C.; Marteau, C.; Franchi, J.; Migliore-Samour, D. Cytochrome P450 4A11 expression in human keratinocytes: effects of ultraviolet irradiation. Br. J. Dermatol., 2001, 145(5), 749-757.
-
(2001)
Br. J. Dermatol
, vol.145
, Issue.5
, pp. 749-757
-
-
Gonzalez, M.C.1
Marteau, C.2
Franchi, J.3
Migliore-Samour, D.4
-
168
-
-
0037228554
-
Differential regulation of human CYP4A genes by peroxisome proliferators and dexamethasone
-
Savas, Ü.; Hsu, M.H.; Johnson, E.F. Differential regulation of human CYP4A genes by peroxisome proliferators and dexamethasone. Arch. Biochem. Biophys., 2003, 409(1), 212-220.
-
(2003)
Arch. Biochem. Biophys
, vol.409
, Issue.1
, pp. 212-220
-
-
Savas, U.1
Hsu, M.H.2
Johnson, E.F.3
-
169
-
-
0029144726
-
Mutagenic activation of 3-methoxy-4-aminoazobenzene by mouse renal cytochrome P450 CYP4B1: Cloning and characterization of mouse CYP4B1
-
Imaoka, S.; Hiroi, T.; Tamura, Y.; Yamazaki, H.; Shimada, T.; Komori, M.; Degawa, M.; Funae, Y. Mutagenic activation of 3-methoxy-4-aminoazobenzene by mouse renal cytochrome P450 CYP4B1: cloning and characterization of mouse CYP4B1. Arch. Biochem. Biophys., 1995, 321(1), 255-262.
-
(1995)
Arch. Biochem. Biophys
, vol.321
, Issue.1
, pp. 255-262
-
-
Imaoka, S.1
Hiroi, T.2
Tamura, Y.3
Yamazaki, H.4
Shimada, T.5
Komori, M.6
Degawa, M.7
Funae, Y.8
-
170
-
-
0036020994
-
Genetic polymorphism of the human cytochrome P450 CYP4B1: Evidence for a non-functional allelic variant
-
Lo-Guidice, J.M.; Allorge, D.; Cauffiez, C.; Chevalier, D.; Lafitte, J.J.; Lhermitte, M.; Broly, F. Genetic polymorphism of the human cytochrome P450 CYP4B1: evidence for a non-functional allelic variant. Pharmacogenetics, 2002, 12(5), 367-374.
-
(2002)
Pharmacogenetics
, vol.12
, Issue.5
, pp. 367-374
-
-
Lo-Guidice, J.M.1
Allorge, D.2
Cauffiez, C.3
Chevalier, D.4
Lafitte, J.J.5
Lhermitte, M.6
Broly, F.7
-
171
-
-
0034669338
-
4 ω-hydroxylase, CYP4F14
-
4 ω-hydroxylase, CYP4F14. Arch. Biochem. Biophys., 2000, 383(2), 225-232.
-
(2000)
Arch. Biochem. Biophys
, vol.383
, Issue.2
, pp. 225-232
-
-
Kikuta, Y.1
Kasyu, H.2
Kusunose, E.3
Kusunose, M.4
-
172
-
-
0035146291
-
Molecular cloning and regulation of expression of two novel mouse CYP4F genes: Expression in peroxisome proliferator-activated receptor α-deficient mice upon lipopolysaccharide and clofibrate challenges
-
Cui, X.; Kawashima, H.; Barclay, T.B.; Peters, J.M.; Gonzalez, F.J.; Morgan, E.T.; Strobel, H.W. Molecular cloning and regulation of expression of two novel mouse CYP4F genes: expression in peroxisome proliferator-activated receptor α-deficient mice upon lipopolysaccharide and clofibrate challenges. J. Pharmacol. Exp. Ther., 2001, 296(2), 542-550.
-
(2001)
J. Pharmacol. Exp. Ther
, vol.296
, Issue.2
, pp. 542-550
-
-
Cui, X.1
Kawashima, H.2
Barclay, T.B.3
Peters, J.M.4
Gonzalez, F.J.5
Morgan, E.T.6
Strobel, H.W.7
-
173
-
-
0034635521
-
Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of CYP4F2 and CYP4A11
-
Lasker, J.M.; Chen, W.B.; Wolf, I.; Bloswick, B.P.; Wilson, P.D.; Powell, P.K. Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of CYP4F2 and CYP4A11. J. Biol. Chem., 2000, 275(6), 4118-4126.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.6
, pp. 4118-4126
-
-
Lasker, J.M.1
Chen, W.B.2
Wolf, I.3
Bloswick, B.P.4
Wilson, P.D.5
Powell, P.K.6
-
174
-
-
0035851164
-
Alternative splicing determines the function of CYP4F3 by switching substrate specificity
-
Christmas, P.; Jones, J.P.; Patten, C.J.; Rock, D.A.; Zheng, Y.; Cheng, S.M.; Weber, B.M.; Carlesso, N.; Scadden, D.T.; Rettie, A.E.; Soberman, R.J. Alternative splicing determines the function of CYP4F3 by switching substrate specificity. J. Biol. Chem., 2001, 276(41), 38166-38172.
-
(2001)
J. Biol. Chem
, vol.276
, Issue.41
, pp. 38166-38172
-
-
Christmas, P.1
Jones, J.P.2
Patten, C.J.3
Rock, D.A.4
Zheng, Y.5
Cheng, S.M.6
Weber, B.M.7
Carlesso, N.8
Scadden, D.T.9
Rettie, A.E.10
Soberman, R.J.11
-
175
-
-
0037223836
-
Expression of CYP4F8 (prostaglandin H 19-hydroxylase) in human epithelia and prominent induction in epidermis of psoriatic lesions
-
Stark, K.; Torma, H.; Cristea, M.; Oliw, E.H. Expression of CYP4F8 (prostaglandin H 19-hydroxylase) in human epithelia and prominent induction in epidermis of psoriatic lesions. Arch. Biochem. Biophys., 2003, 409(1), 188-196.
-
(2003)
Arch. Biochem. Biophys
, vol.409
, Issue.1
, pp. 188-196
-
-
Stark, K.1
Torma, H.2
Cristea, M.3
Oliw, E.H.4
-
176
-
-
0034283075
-
A novel human cytochrome P450 4F isoform (CYP4F11): CDNA cloning, expression, and genomic structural characterization
-
Cui, X.; Nelson, D.R.; Strobel, H.W. A novel human cytochrome P450 4F isoform (CYP4F11): cDNA cloning, expression, and genomic structural characterization. Genomics, 2000, 68(2), 161-166.
-
(2000)
Genomics
, vol.68
, Issue.2
, pp. 161-166
-
-
Cui, X.1
Nelson, D.R.2
Strobel, H.W.3
-
177
-
-
1942437980
-
Expression of CYP4F12 in gastrointestinal and urogenital epithelia
-
Stark, K.; Schauer, L.; Sahlén, G.E.; Ronquist, G.; Oliw, E.H. Expression of CYP4F12 in gastrointestinal and urogenital epithelia. Basic Clin. Pharmacol. Toxicol., 2004, 94(4), 177-183.
-
(2004)
Basic Clin. Pharmacol. Toxicol
, vol.94
, Issue.4
, pp. 177-183
-
-
Stark, K.1
Schauer, L.2
Sahlén, G.E.3
Ronquist, G.4
Oliw, E.H.5
-
178
-
-
0034809149
-
cDNA cloning and expression of CYP4F12, a novel human cytochrome P450
-
Bylund, J.; Bylund, M.; Oliw, E.H. cDNA cloning and expression of CYP4F12, a novel human cytochrome P450. Biochem. Biophys. Res. Commun., 2001, 280(3), 892-897.
-
(2001)
Biochem. Biophys. Res. Commun
, vol.280
, Issue.3
, pp. 892-897
-
-
Bylund, J.1
Bylund, M.2
Oliw, E.H.3
-
179
-
-
33144486941
-
Mutations in a new cytochrome P450 gene in lamellar ichthyosis type 3
-
Lefèvre, C.; Bouadjar, B.; Ferrand, V.; Tadini, G.; Mégarbané, A.; Lathrop, M.; Prud'homme, J.F.; Fischer, J. Mutations in a new cytochrome P450 gene in lamellar ichthyosis type 3. Hum. Mol. Genet., 2006, 15(5), 767-776.
-
(2006)
Hum. Mol. Genet
, vol.15
, Issue.5
, pp. 767-776
-
-
Lefèvre, C.1
Bouadjar, B.2
Ferrand, V.3
Tadini, G.4
Mégarbané, A.5
Lathrop, M.6
Prud'homme, J.F.7
Fischer, J.8
-
180
-
-
33645472062
-
Relative and absolute quantitative expression profiling of cytochromes P450 using isotope-coded affinity tags
-
Jenkins, R.E.; Kitteringham, N.R.; Hunter, C.L.; Webb, S.; Hunt, T.J.; Elsby, R.; Watson, R.B.; Williams, D.; Pennington, S.R.; Park, B.K. Relative and absolute quantitative expression profiling of cytochromes P450 using isotope-coded affinity tags. Proteomics, 2006, 6(6), 1934-1947.
-
(2006)
Proteomics
, vol.6
, Issue.6
, pp. 1934-1947
-
-
Jenkins, R.E.1
Kitteringham, N.R.2
Hunter, C.L.3
Webb, S.4
Hunt, T.J.5
Elsby, R.6
Watson, R.B.7
Williams, D.8
Pennington, S.R.9
Park, B.K.10
-
181
-
-
33747769939
-
Gene expression profiles of mouse retinas during the second and third postnatal weeks
-
Liu, J.; Wang, J.; Huang, Q.; Higdon, J.; Magdaleno, S.; Curran, T.; Zuo, J. Gene expression profiles of mouse retinas during the second and third postnatal weeks. Brain Res., 2006, 1098(1), 113-125.
-
(2006)
Brain Res
, vol.1098
, Issue.1
, pp. 113-125
-
-
Liu, J.1
Wang, J.2
Huang, Q.3
Higdon, J.4
Magdaleno, S.5
Curran, T.6
Zuo, J.7
-
182
-
-
33644941615
-
Cytochrome P450 Cyp4x1 is a major P450 protein in mouse brain
-
Al-Anizy, M.; Horley, N.J.; Kuo, C.W.S.; Gillett, L.C.; Laughton, C.A.; Kendall, D.; Barrett, D.A.; Parker, T.; Bell, D.R. Cytochrome P450 Cyp4x1 is a major P450 protein in mouse brain. FEBS J., 2006, 273(5), 936-947.
-
(2006)
FEBS J
, vol.273
, Issue.5
, pp. 936-947
-
-
Al-Anizy, M.1
Horley, N.J.2
Kuo, C.W.S.3
Gillett, L.C.4
Laughton, C.A.5
Kendall, D.6
Barrett, D.A.7
Parker, T.8
Bell, D.R.9
-
183
-
-
17744383371
-
Conditional regulation of the human CYP4X1 and CYP4Z1 genes
-
Savas, Ü., Hsu, M.H.; Griffin, K.J.; Bell, D.R.; Johnson, E.F. Conditional regulation of the human CYP4X1 and CYP4Z1 genes. Arch. Biochem. Biophys., 2005, 436(2), 377-385.
-
(2005)
Arch. Biochem. Biophys
, vol.436
, Issue.2
, pp. 377-385
-
-
Savas, U.1
Hsu, M.H.2
Griffin, K.J.3
Bell, D.R.4
Johnson, E.F.5
-
184
-
-
50549083650
-
Expression and purification of orphan cytochrome P450 4X1 and oxidation of anandamide
-
Stark, K.; Dostalek, M.; Guengerich, F.P. Expression and purification of orphan cytochrome P450 4X1 and oxidation of anandamide. FEBS J., 2008, 275(14), 3706-3717.
-
(2008)
FEBS J
, vol.275
, Issue.14
, pp. 3706-3717
-
-
Stark, K.1
Dostalek, M.2
Guengerich, F.P.3
-
185
-
-
1942532186
-
Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma
-
Rieger, M.A.; Ebner, R.; Bell, D.R.; Kiessling, A.; Rohayem, J.; Schmitz, M.; Temme, A.; Rieber, E.P.; Weigle, B. Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma. Cancer Res., 2004, 64(7), 2357-2364.
-
(2004)
Cancer Res
, vol.64
, Issue.7
, pp. 2357-2364
-
-
Rieger, M.A.1
Ebner, R.2
Bell, D.R.3
Kiessling, A.4
Rohayem, J.5
Schmitz, M.6
Temme, A.7
Rieber, E.P.8
Weigle, B.9
-
186
-
-
0027301535
-
Molecular cloning and expression of murine thromboxane synthase
-
Zhang, L.; Chase, M.B.; Shen, R.F. Molecular cloning and expression of murine thromboxane synthase. Biochem. Biophys. Res. Commun., 1993, 194(2), 741-748.
-
(1993)
Biochem. Biophys. Res. Commun
, vol.194
, Issue.2
, pp. 741-748
-
-
Zhang, L.1
Chase, M.B.2
Shen, R.F.3
-
187
-
-
0028855905
-
Prostacyclin and thromboxane synthases
-
Tanabe, T.; Ullrich, V. Prostacyclin and thromboxane synthases. J. Lipid Mediat. Cell Signal., 1995, 12(2-3), 243-255.
-
(1995)
J. Lipid Mediat. Cell Signal
, vol.12
, Issue.2-3
, pp. 243-255
-
-
Tanabe, T.1
Ullrich, V.2
-
188
-
-
0028133007
-
Characterization of the human gene (TBXAS1) encoding thromboxane synthase
-
Miyata, A.; Yokoyama, C.; Ihara, H.; Bandoh, S.; Takeda, O.; Takahashi, E.I.; Tanabe, T. Characterization of the human gene (TBXAS1) encoding thromboxane synthase. Eur. J. Biochem., 1994, 224(2), 273-279.
-
(1994)
Eur. J. Biochem
, vol.224
, Issue.2
, pp. 273-279
-
-
Miyata, A.1
Yokoyama, C.2
Ihara, H.3
Bandoh, S.4
Takeda, O.5
Takahashi, E.I.6
Tanabe, T.7
-
189
-
-
0028332262
-
Molecular cloning and expression of human prostacyclin synthase
-
Miyata, A.; Hara, S.; Yokoyama, C.; Inoue, H.; Ullrich, V.; Tanabe, T. Molecular cloning and expression of human prostacyclin synthase. Biochem. Biophys. Res. Commun., 1994, 200(3), 1728-1734.
-
(1994)
Biochem. Biophys. Res. Commun
, vol.200
, Issue.3
, pp. 1728-1734
-
-
Miyata, A.1
Hara, S.2
Yokoyama, C.3
Inoue, H.4
Ullrich, V.5
Tanabe, T.6
-
190
-
-
33947617210
-
Enzymes in the conversion of cholesterol into bile acids
-
Norlin, M.; Wikvall, K. Enzymes in the conversion of cholesterol into bile acids. Curr. Mol. Med., 2007, 7(2), 199-218.
-
(2007)
Curr. Mol. Med
, vol.7
, Issue.2
, pp. 199-218
-
-
Norlin, M.1
Wikvall, K.2
-
191
-
-
0025231590
-
Purification of cholesterol 7α-hydroxylase from human and rat liver and production of inhibiting polyclonal antibodies
-
Nguyen, L.B.; Shefer, S.; Salen, G.; Ness, G.; Tanaka, R.D.; Packin, V.; Thomas, P.; Shore, V.; Batta, A. Purification of cholesterol 7α-hydroxylase from human and rat liver and production of inhibiting polyclonal antibodies. J. Biol. Chem., 1990, 265(8), 4541-4546.
-
(1990)
J. Biol. Chem
, vol.265
, Issue.8
, pp. 4541-4546
-
-
Nguyen, L.B.1
Shefer, S.2
Salen, G.3
Ness, G.4
Tanaka, R.D.5
Packin, V.6
Thomas, P.7
Shore, V.8
Batta, A.9
-
192
-
-
0029589217
-
A novel cytochrome P450 expressed primarily in brain
-
Stapleton, G.; Steel, M.; Richardson, M.; Mason, J.O.; Rose, K.A.; Morris, R.G.M.; Lathe, R. A novel cytochrome P450 expressed primarily in brain. J. Biol. Chem., 1995, 270(50), 29739-29745.
-
(1995)
J. Biol. Chem
, vol.270
, Issue.50
, pp. 29739-29745
-
-
Stapleton, G.1
Steel, M.2
Richardson, M.3
Mason, J.O.4
Rose, K.A.5
Morris, R.G.M.6
Lathe, R.7
-
193
-
-
0030845921
-
Identification and characterization of a mouse oxysterol 7α-hydroxylase cDNA
-
Schwarz, M.; Lund, E.G.; Lathe, R.; Björkhem, I.; Russell, D.W. Identification and characterization of a mouse oxysterol 7α-hydroxylase cDNA. J. Biol. Chem., 1997, 272(38), 23995-24001.
-
(1997)
J. Biol. Chem
, vol.272
, Issue.38
, pp. 23995-24001
-
-
Schwarz, M.1
Lund, E.G.2
Lathe, R.3
Björkhem, I.4
Russell, D.W.5
-
194
-
-
0035962004
-
Ontogeny of the neurosteroid enzyme Cyp7b in the mouse
-
Bean, R.; Seckl, J.R.; Lathe, R.; Martin, C. Ontogeny of the neurosteroid enzyme Cyp7b in the mouse. Mol. Cell. Endocrinol., 2001, 174(1-2), 137-144.
-
(2001)
Mol. Cell. Endocrinol
, vol.174
, Issue.1-2
, pp. 137-144
-
-
Bean, R.1
Seckl, J.R.2
Lathe, R.3
Martin, C.4
-
195
-
-
0033386688
-
Structure and functions of human oxysterol 7α-hydroxylase cDNAs and gene CYP7B1
-
Wu, Z.; Martin, K.O.; Javitt, N.B.; Chiang, J.Y.L. Structure and functions of human oxysterol 7α-hydroxylase cDNAs and gene CYP7B1. J. Lipid Res., 1999, 40(12), 2195-2203.
-
(1999)
J. Lipid Res
, vol.40
, Issue.12
, pp. 2195-2203
-
-
Wu, Z.1
Martin, K.O.2
Javitt, N.B.3
Chiang, J.Y.L.4
-
196
-
-
0033106423
-
Structure and chromosomal assignment of the sterol 12α-hydroxylase gene (CYP8B1) in human and mouse: Eukaryotic cytochrome P-450 gene devoid of introns
-
Gåfvels, M.; Olin, M.; Chowdhary, B.P.; Raudsepp, T.; Andersson, U.; Persson, B.; Jansson, M.; Björkhem, I.; Eggertsen, G. Structure and chromosomal assignment of the sterol 12α-hydroxylase gene (CYP8B1) in human and mouse: eukaryotic cytochrome P-450 gene devoid of introns. Genomics, 1999, 56(2), 184-196.
-
(1999)
Genomics
, vol.56
, Issue.2
, pp. 184-196
-
-
Gåfvels, M.1
Olin, M.2
Chowdhary, B.P.3
Raudsepp, T.4
Andersson, U.5
Persson, B.6
Jansson, M.7
Björkhem, I.8
Eggertsen, G.9
-
197
-
-
12344273662
-
Immunohistochemical detection of the human cytochrome P4507B1: Production of a monoclonal antibody after cDNA immunization
-
Trap, C.; Nato, F.; Chalbot, S.; Kim, S.B.; Lafaye, P.; Morfin, R. Immunohistochemical detection of the human cytochrome P4507B1: production of a monoclonal antibody after cDNA immunization. J. Neuroimmunol., 2005, 159(1-2), 41-47.
-
(2005)
J. Neuroimmunol
, vol.159
, Issue.1-2
, pp. 41-47
-
-
Trap, C.1
Nato, F.2
Chalbot, S.3
Kim, S.B.4
Lafaye, P.5
Morfin, R.6
-
198
-
-
0028068796
-
Atherosclerosis and sterol 27-hydroxylase: Evidence for a role of this enzyme in elimination of cholesterol from human macrophages
-
Björkhem, I.; Andersson, O.; Diczpalusy, U.; Sevastik, B.; Xiu, R.J.; Duan, C.; Lund, E. Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages. Proc. Natl. Acad. Sci. USA, 1994, 91(18), 8592-8596.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, Issue.18
, pp. 8592-8596
-
-
Björkhem, I.1
Andersson, O.2
Diczpalusy, U.3
Sevastik, B.4
Xiu, R.J.5
Duan, C.6
Lund, E.7
-
199
-
-
0034595650
-
Expression cloning of an oxysterol 7α-hydroxylase selective for 24- hydroxycholesterol
-
Li-Hawkins, J.; Lund, E.G.; Bronson, A.D.; Russell, D.W. Expression cloning of an oxysterol 7α-hydroxylase selective for 24- hydroxycholesterol. J. Biol. Chem., 2000, 275(22), 16543-16549.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.22
, pp. 16543-16549
-
-
Li-Hawkins, J.1
Lund, E.G.2
Bronson, A.D.3
Russell, D.W.4
-
200
-
-
0029974620
-
The ubiquitously expressed human CYP51 encodes lanosterol 14α-demethylase, a cytochrome P450 whose expression is regulated by oxysterols
-
Strömstedt, M.; Rozman, D.; Waterman, M.R. The ubiquitously expressed human CYP51 encodes lanosterol 14α-demethylase, a cytochrome P450 whose expression is regulated by oxysterols. Arch. Biochem. Biophys., 1996, 329(1), 73-81.
-
(1996)
Arch. Biochem. Biophys
, vol.329
, Issue.1
, pp. 73-81
-
-
Strömstedt, M.1
Rozman, D.2
Waterman, M.R.3
-
201
-
-
0037154995
-
Lanosterol 14α-demethylase and MAS sterols in mammalian gametogenesis
-
Rozman, D.; Cotman, M.; Frangež, R. Lanosterol 14α-demethylase and MAS sterols in mammalian gametogenesis. Mol. Cell. Endocrinol., 2002, 187(1-2), 179-187.
-
(2002)
Mol. Cell. Endocrinol
, vol.187
, Issue.1-2
, pp. 179-187
-
-
Rozman, D.1
Cotman, M.2
Frangež, R.3
-
202
-
-
0033594903
-
cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain
-
Lund, E.G.; Guileyardo, J.M.; Russell, D.W. cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain. Proc. Natl. Acad. Sci. USA, 1999, 96(13), 7238-7243.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, Issue.13
, pp. 7238-7243
-
-
Lund, E.G.1
Guileyardo, J.M.2
Russell, D.W.3
-
203
-
-
0037475157
-
Predominantly neuronal expression of cytochrome P450 isoforms CYP3A11 and CYP3A13 in mouse brain
-
Hagemeyer, C.E.; Rosenbrock, H.; Ditter, M.; Knoth, R.; Volk, B. Predominantly neuronal expression of cytochrome P450 isoforms CYP3A11 and CYP3A13 in mouse brain. Neuroscience, 2003, 117(3), 521-529.
-
(2003)
Neuroscience
, vol.117
, Issue.3
, pp. 521-529
-
-
Hagemeyer, C.E.1
Rosenbrock, H.2
Ditter, M.3
Knoth, R.4
Volk, B.5
-
204
-
-
0030962170
-
3
-
3. Endocrinology, 1997, 138(6), 2233-2240.
-
(1997)
Endocrinology
, vol.138
, Issue.6
, pp. 2233-2240
-
-
Akeno, N.1
Saikatsu, S.2
Kawane, T.3
Horiuchi, N.4
-
205
-
-
58049193076
-
3 is a natural chemopreventive agent against carcinogen induced precancerous lesions in mouse mammary gland organ culture
-
3 is a natural chemopreventive agent against carcinogen induced precancerous lesions in mouse mammary gland organ culture. Breast Cancer Res. Treat., 2009, 113(1), 31-41.
-
(2009)
Breast Cancer Res. Treat
, vol.113
, Issue.1
, pp. 31-41
-
-
Peng, X.1
Hawthorne, M.2
Vaishnav, A.3
St-Arnaud, R.4
Mehta, R.G.5
-
206
-
-
0033695681
-
Kinetic characteristics of norcocaine N-hydroxylation in mouse and human liver microsomes: Involvement of CYP enzymes
-
Pellinen, P.; Kulmala, L.; Kontilla, J.; Auriola, S.; Pasanen, M.; Juvonen, R. Kinetic characteristics of norcocaine N-hydroxylation in mouse and human liver microsomes: involvement of CYP enzymes. Arch. Toxicol., 2000, 74(99), 511-520.
-
(2000)
Arch. Toxicol
, vol.74
, Issue.99
, pp. 511-520
-
-
Pellinen, P.1
Kulmala, L.2
Kontilla, J.3
Auriola, S.4
Pasanen, M.5
Juvonen, R.6
-
207
-
-
33645839049
-
Coordinated induction of bile acid detoxification and alternative elimination in mice: Role of FXR-regulated organic solute transporter-α/β in the adaptive response to bile acids
-
Zollner, G.; Wagner, M.; Moustafa, T.; Fickert, P.; Silbert, D.; Gumhold, J.; Fuchsbichler, A.; Halilbasic, E.; Denk, H.; Marschall, H.U.; Trauner, M. Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-α/β in the adaptive response to bile acids. Am. J. Physiol. Gastrointest. Liver Physiol. 2006, 290(5), G923-G932.
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.290
, Issue.5
-
-
Zollner, G.1
Wagner, M.2
Moustafa, T.3
Fickert, P.4
Silbert, D.5
Gumhold, J.6
Fuchsbichler, A.7
Halilbasic, E.8
Denk, H.9
Marschall, H.U.10
Trauner, M.11
-
208
-
-
58149250221
-
Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR)
-
Hernandez, J.P.; Mota, L.C.; Huang, W.; Moore, D.D.; Baldwin, W.S. Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR). Toxicology, 2009, 256(1-2), 53-64.
-
(2009)
Toxicology
, vol.256
, Issue.1-2
, pp. 53-64
-
-
Hernandez, J.P.1
Mota, L.C.2
Huang, W.3
Moore, D.D.4
Baldwin, W.S.5
-
209
-
-
0028893368
-
Multiple steroid-binding orientations: Alteration of regiospecificity of dehydroepiandrosterone 2- and 7-hydroxylase activities of cytochrome P-450 2a-5 by mutation of residue 209
-
Iwasaki, M.; Davis, D.G.; Darden, T.A.; Pedersen, L.G.; Negishi, M. Multiple steroid-binding orientations: alteration of regiospecificity of dehydroepiandrosterone 2- and 7-hydroxylase activities of cytochrome P-450 2a-5 by mutation of residue 209. Biochem. J., 1995, 306(1), 29-33.
-
(1995)
Biochem. J
, vol.306
, Issue.1
, pp. 29-33
-
-
Iwasaki, M.1
Davis, D.G.2
Darden, T.A.3
Pedersen, L.G.4
Negishi, M.5
-
210
-
-
0030810985
-
CYP26, a novel mammalian cytochrome P450, is induced by retinoic acid and defines a new family
-
Ray, W.J.; Bain, G.; Yao, M.; Gottlieb, D.I. CYP26, a novel mammalian cytochrome P450, is induced by retinoic acid and defines a new family. J. Biol. Chem., 1997, 272(30), 18702-18708.
-
(1997)
J. Biol. Chem
, vol.272
, Issue.30
, pp. 18702-18708
-
-
Ray, W.J.1
Bain, G.2
Yao, M.3
Gottlieb, D.I.4
-
211
-
-
33745295126
-
Retinoids, eye development, and maturation of visual function
-
Luo, T.; Sakai, Y.; Wagner, E.; Dräger, U.C. Retinoids, eye development, and maturation of visual function. J. Neurobiol., 2006, 66(7), 677-686.
-
(2006)
J. Neurobiol
, vol.66
, Issue.7
, pp. 677-686
-
-
Luo, T.1
Sakai, Y.2
Wagner, E.3
Dräger, U.C.4
-
212
-
-
0033017180
-
Expression of retinoic acid 4-hydroxylase (CYP26) during mouse and Xenopus laevis embryogenesis
-
de Roos, K.; Sonneveld, E.; Compaan, B.; ten Berge, D.; Durston, A.J.; van der Saag, P.T. Expression of retinoic acid 4-hydroxylase (CYP26) during mouse and Xenopus laevis embryogenesis. Mech. Dev., 1999, 82(1-2), 205-211.
-
(1999)
Mech. Dev
, vol.82
, Issue.1-2
, pp. 205-211
-
-
de Roos, K.1
Sonneveld, E.2
Compaan, B.3
ten Berge, D.4
Durston, A.J.5
van der Saag, P.T.6
-
213
-
-
46749092864
-
Expression of RALDHs (ALDH1As) and CYP26s in human tissues and during the neural differentiation of P19 embryonal carcinoma stem cell
-
Xi, J.; Yang, Z. Expression of RALDHs (ALDH1As) and CYP26s in human tissues and during the neural differentiation of P19 embryonal carcinoma stem cell. Gene Expr. Patterns, 2008, 8(6), 438-442.
-
(2008)
Gene Expr. Patterns
, vol.8
, Issue.6
, pp. 438-442
-
-
Xi, J.1
Yang, Z.2
-
214
-
-
57649197948
-
Topical treatment with CYP26 inhibitor talarozole (R115866) dose dependently alters the expression of retinoid-regulated genes in normal human epidermis
-
Pavez Loriè, E.; Cools, M.; Borgers, M.; Wouters, L.; Shroot, B.; Hagforsen, E.; Törmä, H.; Vahlquist, A. Topical treatment with CYP26 inhibitor talarozole (R115866) dose dependently alters the expression of retinoid-regulated genes in normal human epidermis. Br. J. Dermatol., 2009, 160(1), 26-36.
-
(2009)
Br. J. Dermatol
, vol.160
, Issue.1
, pp. 26-36
-
-
Pavez Loriè, E.1
Cools, M.2
Borgers, M.3
Wouters, L.4
Shroot, B.5
Hagforsen, E.6
Törmä, H.7
Vahlquist, A.8
-
215
-
-
0027058038
-
Steroidogenic enzymes: Structure, function, and role in regulation of steroid hormone biosynthesis
-
Hanukoglu, I. Steroidogenic enzymes: structure, function, and role in regulation of steroid hormone biosynthesis. J. Steroid Biochem. Mol. Biol., 1992, 43(8), 779-804.
-
(1992)
J. Steroid Biochem. Mol. Biol
, vol.43
, Issue.8
, pp. 779-804
-
-
Hanukoglu, I.1
-
216
-
-
18044389529
-
Quantitative appreciation of steroidogenic gene expression in mouse tissues: New roles for type 2 5α-reductase, 20α-hydroxysteroid dehydrogenase and estrogen sulfotransferase
-
Luu-The, V.; Pelletier, G.; Labrie, F. Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5α-reductase, 20α-hydroxysteroid dehydrogenase and estrogen sulfotransferase. J. Steroid Biochem. Mol. Biol., 2005, 93(2-5), 269-276.
-
(2005)
J. Steroid Biochem. Mol. Biol
, vol.93
, Issue.2-5
, pp. 269-276
-
-
Luu-The, V.1
Pelletier, G.2
Labrie, F.3
-
217
-
-
27544515571
-
Molecular identity and gene expression of aldosterone synthase cytochrome P450
-
Okamoto, M.; Nonaka, Y.; Takemori, H.; Doi, J. Molecular identity and gene expression of aldosterone synthase cytochrome P450. Biochem. Biophys. Res. Commun., 2005, 338(1), 325-330.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.338
, Issue.1
, pp. 325-330
-
-
Okamoto, M.1
Nonaka, Y.2
Takemori, H.3
Doi, J.4
-
218
-
-
17844397702
-
Metabolism of 2,5-bis(trifluoromethyl)-7-benzyloxy-4-trifluoromethylcoumarin by human hepatic CYP isoforms: Evidence for selectivity towards CYP3A4
-
Renwick, A.B.; Lewis, D.F.V.; Fulford, S.; Surry, D.; Williams, B.; Worboys, P.D.; Cai, X.; Wang, R.W.; Price, R.J.; Lake, B.G.; Evans, D.C. Metabolism of 2,5-bis(trifluoromethyl)-7-benzyloxy-4-trifluoromethylcoumarin by human hepatic CYP isoforms: evidence for selectivity towards CYP3A4. Xenobiotica, 2001, 31(4), 187-204.
-
(2001)
Xenobiotica
, vol.31
, Issue.4
, pp. 187-204
-
-
Renwick, A.B.1
Lewis, D.F.V.2
Fulford, S.3
Surry, D.4
Williams, B.5
Worboys, P.D.6
Cai, X.7
Wang, R.W.8
Price, R.J.9
Lake, B.G.10
Evans, D.C.11
-
219
-
-
17844408291
-
Novel extrahepatic cytochrome P450s
-
Karlgren, M.; Miura, S.I.; Ingelman-Sundberg, M. Novel extrahepatic cytochrome P450s. Toxicol. Appl. Pharmacol., 2005, 207(2), S57-S61.
-
(2005)
Toxicol. Appl. Pharmacol
, vol.207
, Issue.2
-
-
Karlgren, M.1
Miura, S.I.2
Ingelman-Sundberg, M.3
-
220
-
-
50049131787
-
mRNA distribution and heterologous expression of orphan cytochrome P450 20A1
-
Stark, K.; Wu, Z.L.; Bartleson, C.J.; Guengerich, F.P. mRNA distribution and heterologous expression of orphan cytochrome P450 20A1. Drug Metab. Dispos., 2008, 36(9), 1930-1937.
-
(2008)
Drug Metab. Dispos
, vol.36
, Issue.9
, pp. 1930-1937
-
-
Stark, K.1
Wu, Z.L.2
Bartleson, C.J.3
Guengerich, F.P.4
-
221
-
-
0015690391
-
Testicular cytochrome P-450 and iron-sulfur protein as related to steroid metabolism
-
Mason, J.I.; Estabrook, R.W.; Purvis, J.L. Testicular cytochrome P-450 and iron-sulfur protein as related to steroid metabolism. Ann. NY Acad. Sci., 1973, 212, 406-419.
-
(1973)
Ann. NY Acad. Sci
, vol.212
, pp. 406-419
-
-
Mason, J.I.1
Estabrook, R.W.2
Purvis, J.L.3
-
222
-
-
0019805557
-
Aryl hydrocarbon hydroxylase and its components in human lung microsomes
-
Watanabe, M.; Abe, T. Aryl hydrocarbon hydroxylase and its components in human lung microsomes. Gann, 1981, 72(5), 806-810.
-
(1981)
Gann
, vol.72
, Issue.5
, pp. 806-810
-
-
Watanabe, M.1
Abe, T.2
-
223
-
-
0025373150
-
Preparation of brain microsomes with cytochrome P450 activity using calcium aggregation method
-
Ravindranath, V.; Anandatheerthavarada, H.K. Preparation of brain microsomes with cytochrome P450 activity using calcium aggregation method. Anal. Biochem., 1990, 187(2), 310-313.
-
(1990)
Anal. Biochem
, vol.187
, Issue.2
, pp. 310-313
-
-
Ravindranath, V.1
Anandatheerthavarada, H.K.2
-
224
-
-
0027244082
-
Purification of multiple forms of cytochrome P450 from a human brain and reconstitution of catalytic activities
-
Bhamre, S.; Anandatheerathavarada, H.K.; Shankar, S.K.; Boyd, M.R.; Ravindranath, V. Purification of multiple forms of cytochrome P450 from a human brain and reconstitution of catalytic activities. Arch. Biochem. Biophys., 1993, 301(2), 251-255.
-
(1993)
Arch. Biochem. Biophys
, vol.301
, Issue.2
, pp. 251-255
-
-
Bhamre, S.1
Anandatheerathavarada, H.K.2
Shankar, S.K.3
Boyd, M.R.4
Ravindranath, V.5
-
225
-
-
0017261047
-
The involvement of cytochrome P-450 in hepatic microsomal steroid hydroxylation reactions supported by sodium periodate, sodium chlorite, and organic hydroperoxides
-
Hrycay, E.G.; Gustafsson, J.Å.; Ingelman-Sundberg, M.; Ernster, L. The involvement of cytochrome P-450 in hepatic microsomal steroid hydroxylation reactions supported by sodium periodate, sodium chlorite, and organic hydroperoxides. Eur. J. Biochem., 1976, 61(1), 43-52.
-
(1976)
Eur. J. Biochem
, vol.61
, Issue.1
, pp. 43-52
-
-
Hrycay, E.G.1
Gustafsson, J.A.2
Ingelman-Sundberg, M.3
Ernster, L.4
-
226
-
-
19944426178
-
Transgenic mice with a hypomorphic NADPH-cytochrome P450 reductase gene: Effects on development, reproduction, and microsomal cytochrome P450
-
Wu, L.; Cui, H.; Zhang, Q.Y.; Behr, M.; Fang, C.; Weng, Y.; Kluetzman, K.; Swiatek, P.J.; Yang, W.; Kaminsky, L.; Ding, X. Transgenic mice with a hypomorphic NADPH-cytochrome P450 reductase gene: effects on development, reproduction, and microsomal cytochrome P450. J. Pharmacol. Exp. Ther., 2005, 312(1), 35-43.
-
(2005)
J. Pharmacol. Exp. Ther
, vol.312
, Issue.1
, pp. 35-43
-
-
Wu, L.1
Cui, H.2
Zhang, Q.Y.3
Behr, M.4
Fang, C.5
Weng, Y.6
Kluetzman, K.7
Swiatek, P.J.8
Yang, W.9
Kaminsky, L.10
Ding, X.11
-
227
-
-
36849043262
-
Evaluation of cytochrome P450 activity in vitro, using dermal and hepatic microsomes from four species and two keratinocyte cell lines in culture
-
Rolsted K.; Kissmeyer, A.M.; Rist, G.M.; Hansen, S.H. Evaluation of cytochrome P450 activity in vitro, using dermal and hepatic microsomes from four species and two keratinocyte cell lines in culture. Arch. Dermatol. Res., 2008, 300(1), 11-18.
-
(2008)
Arch. Dermatol. Res
, vol.300
, Issue.1
, pp. 11-18
-
-
Rolsted, K.1
Kissmeyer, A.M.2
Rist, G.M.3
Hansen, S.H.4
-
228
-
-
0028882757
-
Developmentally regulated expression of adrenal 17 alpha-hydroxylase cytochrome P450 in the mouse embryo
-
Keeney, D.S.; Jenkins, C.M.; Waterman, M.R. Developmentally regulated expression of adrenal 17 alpha-hydroxylase cytochrome P450 in the mouse embryo. Endocrinology, 1995, 136(11), 4872-4879.
-
(1995)
Endocrinology
, vol.136
, Issue.11
, pp. 4872-4879
-
-
Keeney, D.S.1
Jenkins, C.M.2
Waterman, M.R.3
-
229
-
-
0028817125
-
Immunocytochemical study of cytochrome P450 (1A1/1A2) induction in murine ocular tissues
-
Zhao, C.; Shichi, H. Immunocytochemical study of cytochrome P450 (1A1/1A2) induction in murine ocular tissues. Exp. Eye Res., 1995, 60(2), 143-152.
-
(1995)
Exp. Eye Res
, vol.60
, Issue.2
, pp. 143-152
-
-
Zhao, C.1
Shichi, H.2
-
230
-
-
0031862390
-
Purification and characterization of heterologously expressed mouse CYP2A5 and CYP2G1: Role in metabolic activation of acetaminophen and 2,6-dichlorobenzonitrile in mouse olfactory mucosal microsomes
-
Gu, J.; Zhang, Q.U.; Genter, M.B.; Lipinskas, T.W.; Negishi, M.; Nebert, D.W.; Ding, X. Purification and characterization of heterologously expressed mouse CYP2A5 and CYP2G1: role in metabolic activation of acetaminophen and 2,6-dichlorobenzonitrile in mouse olfactory mucosal microsomes. J. Pharmacol. Exp. Ther., 1998, 285(3), 1287-1295.
-
(1998)
J. Pharmacol. Exp. Ther
, vol.285
, Issue.3
, pp. 1287-1295
-
-
Gu, J.1
Zhang, Q.U.2
Genter, M.B.3
Lipinskas, T.W.4
Negishi, M.5
Nebert, D.W.6
Ding, X.7
-
231
-
-
0032004932
-
Effects of tobacco smoke on the gene expression of the Cyp1a, Cyp2b, Cyp2e, and Cyp3a subfamilies in mouse liver and lung: Relation to single strand breaks of DNA
-
Villard, P.H.; Seree, E.M.; Re, J.L.; De Meo, M.; Barra, Y.; Attolini, L.; Dumenil, G.; Catalin, J.; Durand, A.; Lacarelle, B. Effects of tobacco smoke on the gene expression of the Cyp1a, Cyp2b, Cyp2e, and Cyp3a subfamilies in mouse liver and lung: relation to single strand breaks of DNA. Toxicol. Appl. Pharmacol., 1998, 148(2), 195-204.
-
(1998)
Toxicol. Appl. Pharmacol
, vol.148
, Issue.2
, pp. 195-204
-
-
Villard, P.H.1
Seree, E.M.2
Re, J.L.3
De Meo, M.4
Barra, Y.5
Attolini, L.6
Dumenil, G.7
Catalin, J.8
Durand, A.9
Lacarelle, B.10
-
232
-
-
0032896835
-
Paracrine glucocorticoid activity produced by mouse thymic epithelial cells
-
Pazirandeh, A.; Xue, Y.; Rafter, I.; Sjövall, J.; Jondal, M.; Okret, S. Paracrine glucocorticoid activity produced by mouse thymic epithelial cells. FASEB J., 1999, 13(8), 893-901.
-
(1999)
FASEB J
, vol.13
, Issue.8
, pp. 893-901
-
-
Pazirandeh, A.1
Xue, Y.2
Rafter, I.3
Sjövall, J.4
Jondal, M.5
Okret, S.6
-
233
-
-
19944400762
-
Lipopolysaccharide treatment downregulates the expression of the pregnane X receptor, cyp3a11 and mdr1a genes in mouse placenta
-
Chen, Y.H.; Wang, J.P.; Wang, H.; Sun, M.F.; Wei, L.Z.; Wei, W.; Xu, D.X. Lipopolysaccharide treatment downregulates the expression of the pregnane X receptor, cyp3a11 and mdr1a genes in mouse placenta. Toxicology, 2005, 211(3), 242-252.
-
(2005)
Toxicology
, vol.211
, Issue.3
, pp. 242-252
-
-
Chen, Y.H.1
Wang, J.P.2
Wang, H.3
Sun, M.F.4
Wei, L.Z.5
Wei, W.6
Xu, D.X.7
-
234
-
-
33750000583
-
Cytochrome P450 4F subfamily: At the crossroads of eicosanoid and drug metabolism
-
Kalsotra, A.; Strobel, H.W. Cytochrome P450 4F subfamily: at the crossroads of eicosanoid and drug metabolism. Pharmacol. Ther., 2006, 112(3), 589-611.
-
(2006)
Pharmacol. Ther
, vol.112
, Issue.3
, pp. 589-611
-
-
Kalsotra, A.1
Strobel, H.W.2
-
235
-
-
0029834242
-
Expression of cytochromes P450 in human breast tissue and tumors
-
Huang, Z.; Fasco, M.J.; Figge, H.L.; Keyomarsi, K.; Kaminsky, L.S. Expression of cytochromes P450 in human breast tissue and tumors. Drug Metab. Dispos., 1996, 24(8), 899-905.
-
(1996)
Drug Metab. Dispos
, vol.24
, Issue.8
, pp. 899-905
-
-
Huang, Z.1
Fasco, M.J.2
Figge, H.L.3
Keyomarsi, K.4
Kaminsky, L.S.5
-
236
-
-
0029941924
-
ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin
-
Slominski, A.; Ermak, G.; Mihm, M. ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin. J. Clin. Endocrinol. Metab., 1996, 81(7), 2746-2749.
-
(1996)
J. Clin. Endocrinol. Metab
, vol.81
, Issue.7
, pp. 2746-2749
-
-
Slominski, A.1
Ermak, G.2
Mihm, M.3
-
237
-
-
0034698139
-
Identification of CYP4F8 in human seminal vesicles as a prominent 19-hydroxylase of prostaglandin endoperoxides
-
Bylund, J.; Hidestrand, M.; Ingelman-Sundberg, M.; Oliw, E.H. Identification of CYP4F8 in human seminal vesicles as a prominent 19-hydroxylase of prostaglandin endoperoxides. J. Biol. Chem., 2000, 275(29), 21844-21849.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.29
, pp. 21844-21849
-
-
Bylund, J.1
Hidestrand, M.2
Ingelman-Sundberg, M.3
Oliw, E.H.4
-
238
-
-
0032077398
-
Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues
-
Macé, K.; Bowman, E.D.; Vautravers, P.; Shields, P.G.; Harris, C.C.; Pfeifer, A.M.A. Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues. Eur. J. Cancer, 1998, 34(6), 914-920.
-
(1998)
Eur. J. Cancer
, vol.34
, Issue.6
, pp. 914-920
-
-
Macé, K.1
Bowman, E.D.2
Vautravers, P.3
Shields, P.G.4
Harris, C.C.5
Pfeifer, A.M.A.6
-
239
-
-
34548075902
-
-
Kocombining double acute accenthalmy, K.; Tamási, V.; Kóbori, L.; Sárvári, E.; Pascussi, J.M.; Porrogi, P.; Rozman, D.; Prough, R.A.; Meyer, U.A.; Monostory, K. Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor. Drug Metab. Dispos., 2007, 35(9), 1495-1501.
-
Kocombining double acute accenthalmy, K.; Tamási, V.; Kóbori, L.; Sárvári, E.; Pascussi, J.M.; Porrogi, P.; Rozman, D.; Prough, R.A.; Meyer, U.A.; Monostory, K. Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor. Drug Metab. Dispos., 2007, 35(9), 1495-1501.
-
-
-
-
240
-
-
0015450859
-
Cytochrome P-450 as a microsomal peroxidase in steroid hydroperoxide reduction
-
Hrycay, E.G.; O'Brien, P.J. Cytochrome P-450 as a microsomal peroxidase in steroid hydroperoxide reduction. Arch. Biochem. Biophys., 1972, 153(2), 480-494.
-
(1972)
Arch. Biochem. Biophys
, vol.153
, Issue.2
, pp. 480-494
-
-
Hrycay, E.G.1
O'Brien, P.J.2
-
241
-
-
0036223831
-
Summary of information on human CYP enzymes: Human P450 metabolism data
-
Rendic, S. Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab. Rev., 2002, 34(1-2), 83-448.
-
(2002)
Drug Metab. Rev
, vol.34
, Issue.1-2
, pp. 83-448
-
-
Rendic, S.1
-
242
-
-
8544284075
-
Enzymes involved in the activation and inactivation of vitamin D
-
Prosser, D.E.; Jones, G. Enzymes involved in the activation and inactivation of vitamin D. Trends Biochem. Sci., 2004, 29(12), 664-673.
-
(2004)
Trends Biochem. Sci
, vol.29
, Issue.12
, pp. 664-673
-
-
Prosser, D.E.1
Jones, G.2
-
243
-
-
2342537802
-
Bietti crystalline corneoretinal dystrophy is caused by mutations in the novel gene CYP4V2
-
Li, A.; Jiao, X.; Munier, F.L.; Schorderet, D.F.; Yao, W.; Iwata, F.; Hayakawa, M.; Kanai, A.; Chen, M.S; Lewis, R.A.; Heckenlively, J.; Weleber, R.G.; Traboulsi, E.I.; Zhang, Q.; Xiao, X.; Kaiser-Kupfer, M.; Sergeev, Y.V.; Hejtmancik, J.F. Bietti crystalline corneoretinal dystrophy is caused by mutations in the novel gene CYP4V2. Am. J. Hum. Genet., 2004, 74(5), 817-826.
-
(2004)
Am. J. Hum. Genet
, vol.74
, Issue.5
, pp. 817-826
-
-
Li, A.1
Jiao, X.2
Munier, F.L.3
Schorderet, D.F.4
Yao, W.5
Iwata, F.6
Hayakawa, M.7
Kanai, A.8
Chen, M.S.9
Lewis, R.A.10
Heckenlively, J.11
Weleber, R.G.12
Traboulsi, E.I.13
Zhang, Q.14
Xiao, X.15
Kaiser-Kupfer, M.16
Sergeev, Y.V.17
Hejtmancik, J.F.18
-
244
-
-
31344443943
-
Significance of the minor cytochrome P450 3A isoforms
-
Daly, A.K. Significance of the minor cytochrome P450 3A isoforms. Clin. Pharmacokinet., 2006, 45(1), 13-31.
-
(2006)
Clin. Pharmacokinet
, vol.45
, Issue.1
, pp. 13-31
-
-
Daly, A.K.1
-
245
-
-
0027139782
-
Enzyme-kinetic and immunochemical characteristics of mouse cDNA-expressed, microsomal, and purified CYP1A1 and CYP1A2
-
Tsyrlov, I.B.; Goldfarb, I.S.; Gelboin, H.V. Enzyme-kinetic and immunochemical characteristics of mouse cDNA-expressed, microsomal, and purified CYP1A1 and CYP1A2. Arch. Biochem. Biophys., 1993, 307(2), 259-266.
-
(1993)
Arch. Biochem. Biophys
, vol.307
, Issue.2
, pp. 259-266
-
-
Tsyrlov, I.B.1
Goldfarb, I.S.2
Gelboin, H.V.3
-
246
-
-
34447133377
-
7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes
-
Shertzer, H.G.; Genter, M.B.; Talaska, G.; Curran, C.P.; Nebert, D.W.; Dalton, T.P. 7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes. Carcinogenesis, 2007, 28(6), 1371-1378.
-
(2007)
Carcinogenesis
, vol.28
, Issue.6
, pp. 1371-1378
-
-
Shertzer, H.G.1
Genter, M.B.2
Talaska, G.3
Curran, C.P.4
Nebert, D.W.5
Dalton, T.P.6
-
247
-
-
0031721084
-
Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1
-
Crofts, F.G.; Sutter, T.R.; Strickland, P.T. Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1. Carcinogenesis, 1998, 19(11), 1969-1973.
-
(1998)
Carcinogenesis
, vol.19
, Issue.11
, pp. 1969-1973
-
-
Crofts, F.G.1
Sutter, T.R.2
Strickland, P.T.3
-
248
-
-
0030436261
-
Pregnenolone-7β- hydroxylating activities of yeast-expressed mouse cytochrome P450-1A1 and mouse-tissue microsomes
-
Doostzadeh, J.; Urban, P.; Pompon, D.; Morfin, R. Pregnenolone-7β- hydroxylating activities of yeast-expressed mouse cytochrome P450-1A1 and mouse-tissue microsomes. Eur. J. Biochem., 1996, 242(3), 641-647.
-
(1996)
Eur. J. Biochem
, vol.242
, Issue.3
, pp. 641-647
-
-
Doostzadeh, J.1
Urban, P.2
Pompon, D.3
Morfin, R.4
-
249
-
-
0030720779
-
Effects of cytochrome P450 inhibitors and of steroid hormones on the formation of 7-hydroxylated metabolites of pregnenolone in mouse brain microsomes
-
Doostzadeh, J.; Morfin, R. Effects of cytochrome P450 inhibitors and of steroid hormones on the formation of 7-hydroxylated metabolites of pregnenolone in mouse brain microsomes. J. Endocrinol., 1997, 155(2), 343-350.
-
(1997)
J. Endocrinol
, vol.155
, Issue.2
, pp. 343-350
-
-
Doostzadeh, J.1
Morfin, R.2
-
250
-
-
0031788908
-
Inhibition studies of dehydroepiandrosterone 7α- and 7β- hydroxylation in mouse liver microsomes
-
Doostzadeh, J.; Cotillon, A.C.; Benalychérif, A.; Morfin, R. Inhibition studies of dehydroepiandrosterone 7α- and 7β- hydroxylation in mouse liver microsomes. Steroids, 1998, 63(11), 608-614.
-
(1998)
Steroids
, vol.63
, Issue.11
, pp. 608-614
-
-
Doostzadeh, J.1
Cotillon, A.C.2
Benalychérif, A.3
Morfin, R.4
-
251
-
-
0030609849
-
Pregnenolone-7β-hydroxylating activity of human cytochrome P450-1A1
-
Doostzadeh, J.; Flinois, J.P.; Beaune, P.; and Morfin, R. Pregnenolone-7β-hydroxylating activity of human cytochrome P450-1A1. J. Steroid Biochem. Mol. Biol., 1997, 60(1-2), 147-152.
-
(1997)
J. Steroid Biochem. Mol. Biol
, vol.60
, Issue.1-2
, pp. 147-152
-
-
Doostzadeh, J.1
Flinois, J.P.2
Beaune, P.3
Morfin, R.4
-
252
-
-
0033979574
-
Midazolam and triazolam biotransformation in mouse and human liver microsomes: Relative contribution of CYP3A and CYP2C isoforms
-
Perloff, M.D.; von Moltke, L.L.; Court, M.H.; Kotegawa, T.; Shader, R.I.; Greenblatt, D.J. Midazolam and triazolam biotransformation in mouse and human liver microsomes: relative contribution of CYP3A and CYP2C isoforms. J. Pharmacol. Exp. Ther., 2000, 292(2), 618-628.
-
(2000)
J. Pharmacol. Exp. Ther
, vol.292
, Issue.2
, pp. 618-628
-
-
Perloff, M.D.1
von Moltke, L.L.2
Court, M.H.3
Kotegawa, T.4
Shader, R.I.5
Greenblatt, D.J.6
-
253
-
-
0024326433
-
Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a) pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons
-
Shimada, T.; Martin, M.V.; Pruess-Schwartz, D.; Marnett, L.J.; Guengerich, F.P. Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a) pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons. Cancer Res., 1989, 49(22), 6304-6312.
-
(1989)
Cancer Res
, vol.49
, Issue.22
, pp. 6304-6312
-
-
Shimada, T.1
Martin, M.V.2
Pruess-Schwartz, D.3
Marnett, L.J.4
Guengerich, F.P.5
-
254
-
-
0027077438
-
Characterization of human lung microsomal cytochrome P-450 1A1 and its role in the oxidation of chemical carcinogens
-
Shimada, T.; Yun, C.H.; Yamazaki, H.; Gautier, J.C.; Beaune, P.H.; Guengerich, F.P. Characterization of human lung microsomal cytochrome P-450 1A1 and its role in the oxidation of chemical carcinogens. Mol. Pharmacol., 1992, 41(5), 856-864.
-
(1992)
Mol. Pharmacol
, vol.41
, Issue.5
, pp. 856-864
-
-
Shimada, T.1
Yun, C.H.2
Yamazaki, H.3
Gautier, J.C.4
Beaune, P.H.5
Guengerich, F.P.6
-
255
-
-
0030069518
-
Metabolism of 5-methylchrysene and 6-methylchrysene by human hepatic and pulmonary cytochrome P450 enzymes
-
Koehl, W.; Amin, S.; Staretz, M.E.; Ueng, Y.F.; Yamazaki, H.; Tateishi, T.; Guengerich, F.P.; Hecht, S.S. Metabolism of 5-methylchrysene and 6-methylchrysene by human hepatic and pulmonary cytochrome P450 enzymes. Cancer Res., 1996, 56(2), 316-324.
-
(1996)
Cancer Res
, vol.56
, Issue.2
, pp. 316-324
-
-
Koehl, W.1
Amin, S.2
Staretz, M.E.3
Ueng, Y.F.4
Yamazaki, H.5
Tateishi, T.6
Guengerich, F.P.7
Hecht, S.S.8
-
256
-
-
0034776647
-
9-tetrahydrocannabinol to the corresponding ketones by CYP3A11
-
9-tetrahydrocannabinol to the corresponding ketones by CYP3A11. Drug Metab. Dispos., 2001, 29(11), 1485-1491.
-
(2001)
Drug Metab. Dispos
, vol.29
, Issue.11
, pp. 1485-1491
-
-
Matsunaga, T.1
Tanaka, H.2
Higuchi, S.3
Shibayama, K.4
Kishi, N.5
Watanabe, K.6
Yamamoto, I.7
-
257
-
-
0023354424
-
Expression of P1-450 and P3-450 DNA coding sequences as enzymatically active cytochromes P-450 in mammalian cells
-
Battula, N.; Sagara, J.; Gelboin, H.V. Expression of P1-450 and P3-450 DNA coding sequences as enzymatically active cytochromes P-450 in mammalian cells. Proc. Natl. Acad. Sci. USA, 1987, 84(12), 4073-4077.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, Issue.12
, pp. 4073-4077
-
-
Battula, N.1
Sagara, J.2
Gelboin, H.V.3
-
258
-
-
0024558065
-
Mutagen activation by cDNA-expressed P1450, P3450, and P450a
-
Aoyama, T.; Gonzalez, F.J.; Gelboin, H.V. Mutagen activation by cDNA-expressed P1450, P3450, and P450a. Mol. Carcinog., 1989, 1(4), 253-259.
-
(1989)
Mol. Carcinog
, vol.1
, Issue.4
, pp. 253-259
-
-
Aoyama, T.1
Gonzalez, F.J.2
Gelboin, H.V.3
-
259
-
-
0028085833
-
Regio- and stereo-selective metabolism of phenanthrene by twelve cDNA-expressed human, rodent, and rabbit cytochromes P-450
-
Shou, M.; Korzekwa, K.R.; Krausz, K.W.; Crespi, C.L.; Gonzalez, F.J.; Gelboin, H.V. Regio- and stereo-selective metabolism of phenanthrene by twelve cDNA-expressed human, rodent, and rabbit cytochromes P-450. Cancer Lett., 1994, 83(1-2), 305-313.
-
(1994)
Cancer Lett
, vol.83
, Issue.1-2
, pp. 305-313
-
-
Shou, M.1
Korzekwa, K.R.2
Krausz, K.W.3
Crespi, C.L.4
Gonzalez, F.J.5
Gelboin, H.V.6
-
260
-
-
0027937066
-
The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7,8-dihydrodiol
-
Shou, M.; Korzekwa, K.R.; Crespi, C.L.; Gonzalez, F.J.; Gelboin, H.V. The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7,8-dihydrodiol. Mol. Carcinog., 1994, 10(3), 159-168.
-
(1994)
Mol. Carcinog
, vol.10
, Issue.3
, pp. 159-168
-
-
Shou, M.1
Korzekwa, K.R.2
Crespi, C.L.3
Gonzalez, F.J.4
Gelboin, H.V.5
-
261
-
-
0024314124
-
Human cDNAexpressed cytochrome P450 IA2: Mutagen activation and substrate specificity
-
Aoyama, T.; Gonzalez, F.J.; Gelboin, H.V. Human cDNAexpressed cytochrome P450 IA2: mutagen activation and substrate specificity. Mol. Carcinog., 1989, 2(4), 192-198.
-
(1989)
Mol. Carcinog
, vol.2
, Issue.4
, pp. 192-198
-
-
Aoyama, T.1
Gonzalez, F.J.2
Gelboin, H.V.3
-
262
-
-
0034876318
-
Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P450 1B1 allelic variants and other human cytochromes P450 in Salmonella typhimurium NM2009
-
Shimada, T.; Oda, Y.; Gillam, E.M.J.; Guengerich, F.P.; Inoue, K. Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P450 1B1 allelic variants and other human cytochromes P450 in Salmonella typhimurium NM2009. Drug Metab. Dispos., 2001, 29(9), 1176-1182.
-
(2001)
Drug Metab. Dispos
, vol.29
, Issue.9
, pp. 1176-1182
-
-
Shimada, T.1
Oda, Y.2
Gillam, E.M.J.3
Guengerich, F.P.4
Inoue, K.5
-
263
-
-
33646494635
-
Functional expression of human cytochrome P450 enzymes in Escherichia coli
-
Yun, C.H.; Yim, S.K.; Kim, D.H.; Ahn, T. Functional expression of human cytochrome P450 enzymes in Escherichia coli. Curr. Drug Metab., 2006, 7(4), 411-429.
-
(2006)
Curr. Drug Metab
, vol.7
, Issue.4
, pp. 411-429
-
-
Yun, C.H.1
Yim, S.K.2
Kim, D.H.3
Ahn, T.4
-
264
-
-
0028328463
-
-
Christou, M.; Savas, Ü.; Spink, D.C.; Gierthy, J.F.; Jefcoate, C.R. Co-expression of human CYP1A1 and a human analog of cytochrome P450-EF in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin in the human mammary carcinoma-derived MCF-7 cells. Carcinogenesis, 1994, 15(4), 725-732.
-
Christou, M.; Savas, Ü.; Spink, D.C.; Gierthy, J.F.; Jefcoate, C.R. Co-expression of human CYP1A1 and a human analog of cytochrome P450-EF in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin in the human mammary carcinoma-derived MCF-7 cells. Carcinogenesis, 1994, 15(4), 725-732.
-
-
-
-
265
-
-
0033657888
-
Tissue-specific synthesis and oxidative metabolism of estrogens
-
Jefcoate, C.R.; Liehr, J.G.; Santen, R.J.; Sutter, T.R.; Yager, J.D.; Yue, W.; Santner, S.J.; Tekmal, R.; Demers, L.; Pauley, R.; Naftolin, F.; Mor, G.; Berstein, L. Tissue-specific synthesis and oxidative metabolism of estrogens. J. Natl. Cancer Inst. Monogr., 2000, (27), 95-112.
-
(2000)
J. Natl. Cancer Inst. Monogr
, vol.27
, pp. 95-112
-
-
Jefcoate, C.R.1
Liehr, J.G.2
Santen, R.J.3
Sutter, T.R.4
Yager, J.D.5
Yue, W.6
Santner, S.J.7
Tekmal, R.8
Demers, L.9
Pauley, R.10
Naftolin, F.11
Mor, G.12
Berstein, L.13
-
266
-
-
26844573065
-
Differences in caffeine 3-demethylation activity among inbred mouse strains: A comparison of hepatic Cyp1a2 gene expression between two inbred strains
-
Casley, W.L.; Menzies, J.A.; Girard, M.; Larocque, L.; Mousseau, N.; Whitehouse, L.W.; Moon, T.W. Differences in caffeine 3-demethylation activity among inbred mouse strains: a comparison of hepatic Cyp1a2 gene expression between two inbred strains. Fundam. Appl. Toxicol., 1997, 40(2), 228-237.
-
(1997)
Fundam. Appl. Toxicol
, vol.40
, Issue.2
, pp. 228-237
-
-
Casley, W.L.1
Menzies, J.A.2
Girard, M.3
Larocque, L.4
Mousseau, N.5
Whitehouse, L.W.6
Moon, T.W.7
-
267
-
-
0037098292
-
Differences in caffeine and paraxanthine metabolism between human and murine CYP1A2
-
Labedzki, A.; Buters, J.; Jabrane, W.; Fuhr, U. Differences in caffeine and paraxanthine metabolism between human and murine CYP1A2. Biochem. Pharmacol., 2002, 63(12), 2159-2167.
-
(2002)
Biochem. Pharmacol
, vol.63
, Issue.12
, pp. 2159-2167
-
-
Labedzki, A.1
Buters, J.2
Jabrane, W.3
Fuhr, U.4
-
268
-
-
9144249651
-
Metabolism of human cytochrome P450 marker substrates in mouse: A strain and gender comparison
-
Löfgren, S.; Hagbjörk, A.L.; Ekman, S.; Fransson-Steen, R.; Terelius, Y. Metabolism of human cytochrome P450 marker substrates in mouse: a strain and gender comparison. Xenobiotica, 2004, 34(9), 811-834.
-
(2004)
Xenobiotica
, vol.34
, Issue.9
, pp. 811-834
-
-
Löfgren, S.1
Hagbjörk, A.L.2
Ekman, S.3
Fransson-Steen, R.4
Terelius, Y.5
-
269
-
-
0024164616
-
The genetics of aflatoxin B1 metabolism. Association of the induction of aflatoxin B1-4-hydroxylase with the transcriptional activation of cytochrome P3-450 gene
-
Koser, P.L.; Faletto, M.B.; Maccubbin, A.E.; Gurtoo, H.L. The genetics of aflatoxin B1 metabolism. Association of the induction of aflatoxin B1-4-hydroxylase with the transcriptional activation of cytochrome P3-450 gene. J. Biol. Chem., 1988, 263(25), 12584-12595.
-
(1988)
J. Biol. Chem
, vol.263
, Issue.25
, pp. 12584-12595
-
-
Koser, P.L.1
Faletto, M.B.2
Maccubbin, A.E.3
Gurtoo, H.L.4
-
270
-
-
0036775873
-
Effect of CYP1A2 deficiency on heterocyclic amine DNA adduct levels in mice
-
Snyderwine, E.G.; Yu, M.; Schut, H.A.J.; Knight-Jones, L.; Kimura, S. Effect of CYP1A2 deficiency on heterocyclic amine DNA adduct levels in mice. Food Chem. Toxicol., 2002, 40(10), 1529-1533.
-
(2002)
Food Chem. Toxicol
, vol.40
, Issue.10
, pp. 1529-1533
-
-
Snyderwine, E.G.1
Yu, M.2
Schut, H.A.J.3
Knight-Jones, L.4
Kimura, S.5
-
271
-
-
13844316753
-
Cytochrome P450 activation of arylamines and heterocyclic amines
-
Kim, D.; Guengerich, F.P. Cytochrome P450 activation of arylamines and heterocyclic amines. Annu. Rev. Pharmacol. Toxicol., 2005, 45(1), 27-49.
-
(2005)
Annu. Rev. Pharmacol. Toxicol
, vol.45
, Issue.1
, pp. 27-49
-
-
Kim, D.1
Guengerich, F.P.2
-
272
-
-
0034527283
-
Clozapine pharmacokinetics and pharmacodynamics studied with CYP1A2-null mice
-
Aitchison, K.J.; Jann, M.W.; Zhao, J.H.; Sakai, T.; Zaher, H.; Wolff, K.; Collier, D.A.; Kerwin, R.W.; Gonzalez, F.J. Clozapine pharmacokinetics and pharmacodynamics studied with CYP1A2-null mice. J. Psychopharmacol., 2000, 14(4), 353-359.
-
(2000)
J. Psychopharmacol
, vol.14
, Issue.4
, pp. 353-359
-
-
Aitchison, K.J.1
Jann, M.W.2
Zhao, J.H.3
Sakai, T.4
Zaher, H.5
Wolff, K.6
Collier, D.A.7
Kerwin, R.W.8
Gonzalez, F.J.9
-
273
-
-
22544453632
-
Theophylline pharmacokinetics: Comparison of Cyp1a1( -/ -) and Cyp1a2 ( -/ -) knockout mice, humanized hCYP1A1-1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1 (+/+) wild-type mice
-
Derkenne, S.; Curran, C.P.; Shertzer, H.G.; Dalton, T.P.; Dragin, N.; Nebert, D.W. Theophylline pharmacokinetics: comparison of Cyp1a1( -/ -) and Cyp1a2 ( -/ -) knockout mice, humanized hCYP1A1-1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1 (+/+) wild-type mice. Pharmacogenet. Genomics, 2005, 15(7), 503-511.
-
(2005)
Pharmacogenet. Genomics
, vol.15
, Issue.7
, pp. 503-511
-
-
Derkenne, S.1
Curran, C.P.2
Shertzer, H.G.3
Dalton, T.P.4
Dragin, N.5
Nebert, D.W.6
-
274
-
-
0029867020
-
Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism
-
Liang, H.C.L.; Li, H.; McKinnon, R.A.; Duffy, J.J.; Potter, S.S.; Puga, A.; Nebert, D.W. Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism. Proc. Natl. Acad. Sci. USA, 1996, 93(4), 1671-1676.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, Issue.4
, pp. 1671-1676
-
-
Liang, H.C.L.1
Li, H.2
McKinnon, R.A.3
Duffy, J.J.4
Potter, S.S.5
Puga, A.6
Nebert, D.W.7
-
275
-
-
0025139365
-
Characterization of a novel cytochrome P450 from the transformable cell line, C3H/10T1/2
-
Pottenger, L.H.; Jefcoate, C.R. Characterization of a novel cytochrome P450 from the transformable cell line, C3H/10T1/2. Carcinogenesis, 1990, 11(2), 321-327.
-
(1990)
Carcinogenesis
, vol.11
, Issue.2
, pp. 321-327
-
-
Pottenger, L.H.1
Jefcoate, C.R.2
-
276
-
-
0035976381
-
Cytochrome P450 isozymes involved in the metabolism of phenol, a benzene metabolite
-
Powley, M.W.; Carlson, G.P. Cytochrome P450 isozymes involved in the metabolism of phenol, a benzene metabolite. Toxicol. Lett., 2001, 125(1-3), 117-123.
-
(2001)
Toxicol. Lett
, vol.125
, Issue.1-3
, pp. 117-123
-
-
Powley, M.W.1
Carlson, G.P.2
-
277
-
-
0028279667
-
Inhibitors of alprazolam metabolism in vitro: Effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine
-
von Moltke, L.L.; Greenblatt, D.J.; Cotreau-Bibbo, M.M.; Harmatz, J.S.; Shader, R.I. Inhibitors of alprazolam metabolism in vitro: effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine. Br. J. Clin. Pharmacol., 1994, 38(1), 23-31.
-
(1994)
Br. J. Clin. Pharmacol
, vol.38
, Issue.1
, pp. 23-31
-
-
von Moltke, L.L.1
Greenblatt, D.J.2
Cotreau-Bibbo, M.M.3
Harmatz, J.S.4
Shader, R.I.5
-
278
-
-
0034234231
-
Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene
-
Heidel, S.M.; MacWilliams, P.S.; Baird, W.M.; Dashwood, W.M.; Buters, J.T.M.; Gonzalez, F.J.; Larsen, M.C.; Czuprynski, C.J.; Jefcoate, C.R. Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene. Cancer Res., 2000, 60(13), 3454-3460.
-
(2000)
Cancer Res
, vol.60
, Issue.13
, pp. 3454-3460
-
-
Heidel, S.M.1
MacWilliams, P.S.2
Baird, W.M.3
Dashwood, W.M.4
Buters, J.T.M.5
Gonzalez, F.J.6
Larsen, M.C.7
Czuprynski, C.J.8
Jefcoate, C.R.9
-
279
-
-
10844248510
-
Role of cytochrome P4501 family members in the metabolic activation of polycyclic aromatic hydrocarbons in mouse epidermis
-
Kleiner, H.E.; Vulimiri, S.V.; Hatten, W.B.; Reed, M.J.; Nebert, D.W.; Jefcoate, C.R.; DiGiovanni, J. Role of cytochrome P4501 family members in the metabolic activation of polycyclic aromatic hydrocarbons in mouse epidermis. Chem. Res. Toxicol., 2004, 17(12), 1667-1674.
-
(2004)
Chem. Res. Toxicol
, vol.17
, Issue.12
, pp. 1667-1674
-
-
Kleiner, H.E.1
Vulimiri, S.V.2
Hatten, W.B.3
Reed, M.J.4
Nebert, D.W.5
Jefcoate, C.R.6
DiGiovanni, J.7
-
280
-
-
0033655310
-
Estrogens as endogenous genotoxic agents-DNA adducts and mutations
-
Cavalieri, E.; Frenkel, K.; Liehr, J.G.; Rogan, E.; Roy, D. Estrogens as endogenous genotoxic agents-DNA adducts and mutations. J. Natl. Cancer Inst. Monogr., 2000, (27), 75-93.
-
(2000)
J. Natl. Cancer Inst. Monogr
, vol.27
, pp. 75-93
-
-
Cavalieri, E.1
Frenkel, K.2
Liehr, J.G.3
Rogan, E.4
Roy, D.5
-
281
-
-
0037328718
-
CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: Correlation of CYP1B1-mediated DNA adducts with carcinogenicity
-
Buters, J.; Quintanilla-Martinez, L.; Schober, W.; Soballa, V.J.; Hintermair, J.; Wolff, T.; Gonzalez, F.J.; Greim, H. CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity. Carcinogenesis, 2003, 24(2), 327-334.
-
(2003)
Carcinogenesis
, vol.24
, Issue.2
, pp. 327-334
-
-
Buters, J.1
Quintanilla-Martinez, L.2
Schober, W.3
Soballa, V.J.4
Hintermair, J.5
Wolff, T.6
Gonzalez, F.J.7
Greim, H.8
-
282
-
-
0031573465
-
Biological oxidations and P450 reactions. Recombinant mouse CYP1B1 expressed in Escherichia coli exhibits selective binding by polycyclic hydrocarbons and metabolism which parallels C3H10T1/2 cell microsomes, but differs from human recombinant CYP1B1
-
Savas, Ü.; Carstens, C.P.; Jefcoate, C.R. Biological oxidations and P450 reactions. Recombinant mouse CYP1B1 expressed in Escherichia coli exhibits selective binding by polycyclic hydrocarbons and metabolism which parallels C3H10T1/2 cell microsomes, but differs from human recombinant CYP1B1. Arch. Biochem. Biophys., 1997, 347(2), 181-192.
-
(1997)
Arch. Biochem. Biophys
, vol.347
, Issue.2
, pp. 181-192
-
-
Savas, U.1
Carstens, C.P.2
Jefcoate, C.R.3
-
283
-
-
0035036154
-
Regulation, function, and tissue-specific expression of cytochrome P450 CYP1B1
-
Murray, G.I.; Melvin, W.T.; Greenlee, W.F.; Burke, M.D. Regulation, function, and tissue-specific expression of cytochrome P450 CYP1B1. Annu. Rev. Pharmacol. Toxicol., 2001, 41, 297-316.
-
(2001)
Annu. Rev. Pharmacol. Toxicol
, vol.41
, pp. 297-316
-
-
Murray, G.I.1
Melvin, W.T.2
Greenlee, W.F.3
Burke, M.D.4
-
284
-
-
0032903944
-
Immortalized human corneal epithelial cells for ocular toxicity and inflammation studies
-
Offord, E.A.; Sharif, N.A.; Macé, K.; Tromvoukis, Y.; Spillare, E.A.; Avanti, O.; Howe, W.E.; Pfeifer, A.M.A. Immortalized human corneal epithelial cells for ocular toxicity and inflammation studies. Invest. Ophthalmol. Vis. Sci., 1999, 40(6), 1091-1101.
-
(1999)
Invest. Ophthalmol. Vis. Sci
, vol.40
, Issue.6
, pp. 1091-1101
-
-
Offord, E.A.1
Sharif, N.A.2
Macé, K.3
Tromvoukis, Y.4
Spillare, E.A.5
Avanti, O.6
Howe, W.E.7
Pfeifer, A.M.A.8
-
285
-
-
33747841594
-
Regulation of constitutive mouse hepatic cytochromes P450 and growth hormone signaling components by 3-methylcholanthrene
-
Lee, C.; Hutson, J.R.; Tzau, V.K.; Riddick, D.S. Regulation of constitutive mouse hepatic cytochromes P450 and growth hormone signaling components by 3-methylcholanthrene. Drug Metab. Dispos., 2006, 34(9), 1530-1538.
-
(2006)
Drug Metab. Dispos
, vol.34
, Issue.9
, pp. 1530-1538
-
-
Lee, C.1
Hutson, J.R.2
Tzau, V.K.3
Riddick, D.S.4
-
286
-
-
0141890076
-
Dose-response studies on the induction of liver cytochromes P4501A1 and 1B1 by polycyclic aromatic hydrocarbons in arylhydrocarbon-responsive C57BL/6J mice
-
Shimada, T.; Sugie, A.; Yamada, T.; Kawazoe, H.; Hashimoto, M.; Azuma, E.; Nakajima, T.; Inoue, K.; Oda, Y. Dose-response studies on the induction of liver cytochromes P4501A1 and 1B1 by polycyclic aromatic hydrocarbons in arylhydrocarbon-responsive C57BL/6J mice. Xenobiotica, 2003, 33(9), 957-971.
-
(2003)
Xenobiotica
, vol.33
, Issue.9
, pp. 957-971
-
-
Shimada, T.1
Sugie, A.2
Yamada, T.3
Kawazoe, H.4
Hashimoto, M.5
Azuma, E.6
Nakajima, T.7
Inoue, K.8
Oda, Y.9
-
287
-
-
3242682298
-
Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1B1
-
Choudhary, D.; Jansson, I.; Stoilov, I.; Sarfarazi, M.; Schenkman, J.B. Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1B1. Drug Metab. Dispos., 2004, 32(8), 840-847.
-
(2004)
Drug Metab. Dispos
, vol.32
, Issue.8
, pp. 840-847
-
-
Choudhary, D.1
Jansson, I.2
Stoilov, I.3
Sarfarazi, M.4
Schenkman, J.B.5
-
288
-
-
15344344226
-
Metabolism of melatonin by human cytochromes P450
-
Ma, X.; Idle, J.R.; Krausz, K.W.; Gonzalez, F.J. Metabolism of melatonin by human cytochromes P450. Drug Metab. Dispos., 2005, 33(4), 489-494.
-
(2005)
Drug Metab. Dispos
, vol.33
, Issue.4
, pp. 489-494
-
-
Ma, X.1
Idle, J.R.2
Krausz, K.W.3
Gonzalez, F.J.4
-
289
-
-
0025122419
-
Catechol estrogen formation in the mouse uterus and its role in implantation
-
Paria, B.C.; Chakraborty, C.; Dey, S.K. Catechol estrogen formation in the mouse uterus and its role in implantation. Mol. Cell. Endocrinol., 1990, 69(1), 25-32.
-
(1990)
Mol. Cell. Endocrinol
, vol.69
, Issue.1
, pp. 25-32
-
-
Paria, B.C.1
Chakraborty, C.2
Dey, S.K.3
-
290
-
-
0033783376
-
NADPH- and hydroperoxide-supported 17β-estradiol hydroxylation catalyzed by a variant form (432L, 453S) of human cytochrome P450 1B1
-
Spink, D.C.; Spink, B.C.; Zhuo, X.; Hussain, M.M.; Gierthy, J.F.; Ding,
-
(2000)
J. Steroid Biochem. Mol. Biol
, vol.74
, Issue.1-2
, pp. 11-18
-
-
Spink, D.C.1
Spink, B.C.2
Zhuo, X.3
Hussain, M.M.4
Gierthy, J.F.5
Ding, X.6
-
291
-
-
33646678925
-
Physiological significance and expression of P450s in the developing eye
-
Choudhary, D.; Jansson, I.; Sarfarazi, M.; Schenkman, J.B. Physiological significance and expression of P450s in the developing eye. Drug Metab. Rev., 2006, 38(1-2), 337-352.
-
(2006)
Drug Metab. Rev
, vol.38
, Issue.1-2
, pp. 337-352
-
-
Choudhary, D.1
Jansson, I.2
Sarfarazi, M.3
Schenkman, J.B.4
-
292
-
-
34249048046
-
Cyp1b1 protein in the mouse eye during development: An immunohistochemical study
-
Choudhary, D.; Jansson, I.; Rezaul, K.; Han, D.K.M.; Sarfarazi, M.; Schenkman, J.B. Cyp1b1 protein in the mouse eye during development: an immunohistochemical study. Drug Metab. Dispos., 2007, 35(6), 987-994.
-
(2007)
Drug Metab. Dispos
, vol.35
, Issue.6
, pp. 987-994
-
-
Choudhary, D.1
Jansson, I.2
Rezaul, K.3
Han, D.K.M.4
Sarfarazi, M.5
Schenkman, J.B.6
-
293
-
-
0028574698
-
-
Spink, D.C.; Hayes, C.L.; Young, N.R.; Christou, M.; Sutter, T.R.; Jefcoate, C.R.; Gierthy, J.F. The effects of 2,3,7,8-tetrachlorodibenzo- p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: evidence for induction of a novel 17β-estradiol 4-hydroxylase. J. Steroid Biochem. Mol. Biol., 1994, 51(5-6), 251-258.
-
Spink, D.C.; Hayes, C.L.; Young, N.R.; Christou, M.; Sutter, T.R.; Jefcoate, C.R.; Gierthy, J.F. The effects of 2,3,7,8-tetrachlorodibenzo- p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: evidence for induction of a novel 17β-estradiol 4-hydroxylase. J. Steroid Biochem. Mol. Biol., 1994, 51(5-6), 251-258.
-
-
-
-
294
-
-
0034721159
-
Humanized xenobiotic response in mice expressing nuclear receptor SXR
-
Xie, W.; Barwick, J.L.; Downes, M.; Blumberg, B.; Simon, C.M.; Nelson, M.C.; Neuschwander-Tetri, B.A.; Brunt, E.M.; Guzelian, P.S.; Evans, R.M. Humanized xenobiotic response in mice expressing nuclear receptor SXR. Nature, 2000, 406(6794), 435-439.
-
(2000)
Nature
, vol.406
, Issue.6794
, pp. 435-439
-
-
Xie, W.1
Barwick, J.L.2
Downes, M.3
Blumberg, B.4
Simon, C.M.5
Nelson, M.C.6
Neuschwander-Tetri, B.A.7
Brunt, E.M.8
Guzelian, P.S.9
Evans, R.M.10
-
295
-
-
0032168855
-
Recombinant human cytochrome P450 1B1 expression in Escherichia coli
-
Shimada, T.; Wunsch, R.M.; Hanna, I.H.; Sutter, T.R.; Guengerich, F.P.; Gillam, E.M.J. Recombinant human cytochrome P450 1B1 expression in Escherichia coli. Arch. Biochem. Biophys., 1998, 357(1), 111-120.
-
(1998)
Arch. Biochem. Biophys
, vol.357
, Issue.1
, pp. 111-120
-
-
Shimada, T.1
Wunsch, R.M.2
Hanna, I.H.3
Sutter, T.R.4
Guengerich, F.P.5
Gillam, E.M.J.6
-
296
-
-
0042315387
-
Characterization of the oxidative metabolites of 17β-estradiol and estrone formed by 15 selectively expressed human cytochrome P450 isoforms
-
Lee, A.J.; Cai, M.X.; Thomas, P.E.; Conney, A.H.; Zhu, B.T. Characterization of the oxidative metabolites of 17β-estradiol and estrone formed by 15 selectively expressed human cytochrome P450 isoforms. Endocrinology, 2003, 144(8), 3382-3398.
-
(2003)
Endocrinology
, vol.144
, Issue.8
, pp. 3382-3398
-
-
Lee, A.J.1
Cai, M.X.2
Thomas, P.E.3
Conney, A.H.4
Zhu, B.T.5
-
297
-
-
0142169943
-
Bioactivation of clozapine by murine cardiac tissue in vivo and in vitro
-
Williams, D.P.; O'Donnell, C.J.; Maggs, J.L.; Leeder, J.S.; Uetrecht, J.; Pirmohamed, M.; Park, B.K. Bioactivation of clozapine by murine cardiac tissue in vivo and in vitro. Chem. Res. Toxicol., 2003, 16(10), 1359-1364.
-
(2003)
Chem. Res. Toxicol
, vol.16
, Issue.10
, pp. 1359-1364
-
-
Williams, D.P.1
O'Donnell, C.J.2
Maggs, J.L.3
Leeder, J.S.4
Uetrecht, J.5
Pirmohamed, M.6
Park, B.K.7
-
298
-
-
26944445430
-
Evidence for induced microsomal bilirubin degradation by cytochrome P450 2A5
-
Abu-Bakar, A.; Moore, M.R.; Lang, M.A. Evidence for induced microsomal bilirubin degradation by cytochrome P450 2A5. Biochem. Pharmacol., 2005, 70(10), 1527-1535.
-
(2005)
Biochem. Pharmacol
, vol.70
, Issue.10
, pp. 1527-1535
-
-
Abu-Bakar, A.1
Moore, M.R.2
Lang, M.A.3
-
299
-
-
0031427202
-
The structure, function, and regulation of cytochrome P450 2A enzymes
-
Honkakoski, P.; Negishi, M. The structure, function, and regulation of cytochrome P450 2A enzymes. Drug Metab. Rev., 1997, 29(4), 977-996.
-
(1997)
Drug Metab. Rev
, vol.29
, Issue.4
, pp. 977-996
-
-
Honkakoski, P.1
Negishi, M.2
-
300
-
-
0034671775
-
Characterization of cytochrome P450 2A4 and 2A5-catalyzed 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism
-
Felicia, N.D.; Rekha, G.K.; Murphy, S.E. Characterization of cytochrome P450 2A4 and 2A5-catalyzed 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism. Arch. Biochem. Biophys., 2000, 384(2), 418-424.
-
(2000)
Arch. Biochem. Biophys
, vol.384
, Issue.2
, pp. 418-424
-
-
Felicia, N.D.1
Rekha, G.K.2
Murphy, S.E.3
-
301
-
-
0030615123
-
Interaction of aflatoxin B1 with cytochrome P450 2A5 and its mutants: Correlation with metabolic activation and toxicity
-
Pelkonen, P.; Lang, M.A.; Negishi, M.; Wild, C.P.; Juvonen, R.O. Interaction of aflatoxin B1 with cytochrome P450 2A5 and its mutants: correlation with metabolic activation and toxicity. Chem. Res. Toxicol., 1997, 10(1), 85-90.
-
(1997)
Chem. Res. Toxicol
, vol.10
, Issue.1
, pp. 85-90
-
-
Pelkonen, P.1
Lang, M.A.2
Negishi, M.3
Wild, C.P.4
Juvonen, R.O.5
-
302
-
-
0027270458
-
High variability of nitrosamine metabolism among individuals: Role of cytochromes P450 2A6 and 2E1 in the dealkylation of Nnitrosodimethylamine and N-nitrosodiethylamine in mice and humans
-
Camus, A.M.; Geneste, O.; Honkakoski, P.; Béréziat, J.C.; Henderson, C.J.; Wolf, R.C.; Bartsch, H.; Lang, M.A. High variability of nitrosamine metabolism among individuals: role of cytochromes P450 2A6 and 2E1 in the dealkylation of Nnitrosodimethylamine and N-nitrosodiethylamine in mice and humans. Mol. Carcinog., 1993, 7(4), 268-275.
-
(1993)
Mol. Carcinog
, vol.7
, Issue.4
, pp. 268-275
-
-
Camus, A.M.1
Geneste, O.2
Honkakoski, P.3
Béréziat, J.C.4
Henderson, C.J.5
Wolf, R.C.6
Bartsch, H.7
Lang, M.A.8
-
303
-
-
0038311641
-
Synthesis of stereospecifically deuterated 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) diastereomers and metabolism by A/J mouse lung microsomes and cytochrome P450 2A5
-
Jalas, J.R.; Hecht, S.S. Synthesis of stereospecifically deuterated 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) diastereomers and metabolism by A/J mouse lung microsomes and cytochrome P450 2A5. Chem. Res. Toxicol., 2003, 16(6), 782-793.
-
(2003)
Chem. Res. Toxicol
, vol.16
, Issue.6
, pp. 782-793
-
-
Jalas, J.R.1
Hecht, S.S.2
-
304
-
-
12144265866
-
Cytochrome P450 2Acatalyzed metabolic activation of structurally similar carcinogenic nitrosamines: N'-nitrosonornicotine enantiomers, Nnitrosopiperidine, and N-nitrosopyrrolidine
-
Wong, H.L.; Murphy, S.E.; Hecht, S.S. Cytochrome P450 2Acatalyzed metabolic activation of structurally similar carcinogenic nitrosamines: N'-nitrosonornicotine enantiomers, Nnitrosopiperidine, and N-nitrosopyrrolidine. Chem. Res. Toxicol., 2005, 18(1), 61-69.
-
(2005)
Chem. Res. Toxicol
, vol.18
, Issue.1
, pp. 61-69
-
-
Wong, H.L.1
Murphy, S.E.2
Hecht, S.S.3
-
305
-
-
22944440387
-
Nicotine 5'-oxidation and methyl oxidation by P450 2A enzymes
-
Murphy, S.E.; Raulinaitis, V.; Brown, K.M. Nicotine 5'-oxidation and methyl oxidation by P450 2A enzymes. Drug Metab. Dispos., 2005, 33(8), 1166-1173.
-
(2005)
Drug Metab. Dispos
, vol.33
, Issue.8
, pp. 1166-1173
-
-
Murphy, S.E.1
Raulinaitis, V.2
Brown, K.M.3
-
306
-
-
0029862553
-
Baculovirus-mediated expression and characterization of rat CYP2A3 and human CYP2A6: Role in metabolic activation of nasal toxicants
-
Liu, C.; Zhuo, X.; Gonzalez, F.J.; Ding, X. Baculovirus-mediated expression and characterization of rat CYP2A3 and human CYP2A6: role in metabolic activation of nasal toxicants. Mol. Pharmacol., 1996, 50(4), 781-788.
-
(1996)
Mol. Pharmacol
, vol.50
, Issue.4
, pp. 781-788
-
-
Liu, C.1
Zhuo, X.2
Gonzalez, F.J.3
Ding, X.4
-
307
-
-
0033539937
-
Cytochrome P450 and steroid hydroxylase activity in mouse olfactory and vomeronasal mucosa
-
Gu, J.; Dudley, C.; Su, T.; Spink, D.C.; Zhang, Q.Y.; Moss, R.L.; Ding, X. Cytochrome P450 and steroid hydroxylase activity in mouse olfactory and vomeronasal mucosa. Biochem. Biophys. Res. Commun., 1999, 266(1), 262-267.
-
(1999)
Biochem. Biophys. Res. Commun
, vol.266
, Issue.1
, pp. 262-267
-
-
Gu, J.1
Dudley, C.2
Su, T.3
Spink, D.C.4
Zhang, Q.Y.5
Moss, R.L.6
Ding, X.7
-
308
-
-
0031949068
-
Oxidation of acetaminophen to its toxic quinone imine and nontoxic catechol metabolites by baculovirus-expressed and purified human cytochromes P450 2E1 and 2A6
-
Chen, W.; Koenigs, L.L.; Thompson, S.J.; Peter, R.M.; Rettie, A.E.; Trager, W.F.; Nelson, S.D. Oxidation of acetaminophen to its toxic quinone imine and nontoxic catechol metabolites by baculovirus-expressed and purified human cytochromes P450 2E1 and 2A6. Chem. Res. Toxicol., 1998, 11(4), 295-301.
-
(1998)
Chem. Res. Toxicol
, vol.11
, Issue.4
, pp. 295-301
-
-
Chen, W.1
Koenigs, L.L.2
Thompson, S.J.3
Peter, R.M.4
Rettie, A.E.5
Trager, W.F.6
Nelson, S.D.7
-
309
-
-
0027175349
-
7α): Role of residue-209 in determining steroid-cytochrome P-450 interaction
-
7α): role of residue-209 in determining steroid-cytochrome P-450 interaction. Biochem. J., 1993, 291(2), 569-573.
-
(1993)
Biochem. J
, vol.291
, Issue.2
, pp. 569-573
-
-
Iwasaki, M.1
Lindberg, R.L.P.2
Juvonen, R.O.3
Negishi, M.4
-
310
-
-
0026762428
-
Distinct induction profiles of three phenobarbital-responsive mouse liver cytochrome P450 isozymes
-
Honkakoski, P.; Auriola, S.; Lang, M.A. Distinct induction profiles of three phenobarbital-responsive mouse liver cytochrome P450 isozymes. Biochem. Pharmacol., 1992, 43(10), 2121-2128.
-
(1992)
Biochem. Pharmacol
, vol.43
, Issue.10
, pp. 2121-2128
-
-
Honkakoski, P.1
Auriola, S.2
Lang, M.A.3
-
311
-
-
0344097277
-
Induction of cytochrome P-450 enzymes after repeated exposure to 4-vinylcyclohexene in B6C3F1 mice
-
Doerr-Stevens, J.K.; Liu, J.; Stevens, G.J.; Kraner, J.C.; Fontaine, S.M.; Halpert, J.R.; Sipes, I.G. Induction of cytochrome P-450 enzymes after repeated exposure to 4-vinylcyclohexene in B6C3F1 mice. Drug Metab. Dispos., 1999, 27(2), 281-287.
-
(1999)
Drug Metab. Dispos
, vol.27
, Issue.2
, pp. 281-287
-
-
Doerr-Stevens, J.K.1
Liu, J.2
Stevens, G.J.3
Kraner, J.C.4
Fontaine, S.M.5
Halpert, J.R.6
Sipes, I.G.7
-
312
-
-
12844280070
-
Evidence that cytochrome P450 CYP2B19 is the major source of epoxyeicosatrienoic acids in mouse skin
-
Du, L.; Yermalitsky, V.; Ladd, P.A.; Capdevila, J.H.; Mernaugh, R.; Keeney, D.S. Evidence that cytochrome P450 CYP2B19 is the major source of epoxyeicosatrienoic acids in mouse skin. Arch. Biochem. Biophys., 2005, 435(1), 125-133.
-
(2005)
Arch. Biochem. Biophys
, vol.435
, Issue.1
, pp. 125-133
-
-
Du, L.1
Yermalitsky, V.2
Ladd, P.A.3
Capdevila, J.H.4
Mernaugh, R.5
Keeney, D.S.6
-
313
-
-
0031937118
-
Differential induction of Cyp1a1, Cyp1b1, Ahd4, and Nmo1 in murine skin tumors and adjacent normal epidermis by ligands of the aryl hydrocarbon receptor
-
Reiners, J.J.; Jones, C.L.; Hong, N.; Myrand, S.P. Differential induction of Cyp1a1, Cyp1b1, Ahd4, and Nmo1 in murine skin tumors and adjacent normal epidermis by ligands of the aryl hydrocarbon receptor. Mol. Carcinog., 1998, 21(2), 135-146.
-
(1998)
Mol. Carcinog
, vol.21
, Issue.2
, pp. 135-146
-
-
Reiners, J.J.1
Jones, C.L.2
Hong, N.3
Myrand, S.P.4
-
314
-
-
0035130457
-
Possible function of astrocyte cytochrome P450 in control of xenobiotic phenytoin in the brain: In vitro studies on murine astrocyte primary cultures
-
Meyer, R.P.; Knoth, R.; Schiltz, E.; Volk, B. Possible function of astrocyte cytochrome P450 in control of xenobiotic phenytoin in the brain: in vitro studies on murine astrocyte primary cultures. Exp. Neurol., 2001, 167(2), 376-384.
-
(2001)
Exp. Neurol
, vol.167
, Issue.2
, pp. 376-384
-
-
Meyer, R.P.1
Knoth, R.2
Schiltz, E.3
Volk, B.4
-
315
-
-
0034789597
-
Oxidative hydrolysis of scoparone by cytochrome P450 CYP2C29 reveals a novel metabolite
-
Meyer, R.P.; Hagemeyer, C.E.; Knoth, R.; Kurz, G.; Volk, B. Oxidative hydrolysis of scoparone by cytochrome P450 CYP2C29 reveals a novel metabolite. Biochem. Biophys. Res. Commun., 2001, 285(1), 32-39.
-
(2001)
Biochem. Biophys. Res. Commun
, vol.285
, Issue.1
, pp. 32-39
-
-
Meyer, R.P.1
Hagemeyer, C.E.2
Knoth, R.3
Kurz, G.4
Volk, B.5
-
316
-
-
0028177942
-
Cocaine Ndemethylation and the metabolism-related hepatotoxicity can be prevented by cytochrome P450 3A inhibitors
-
Pellinen, P.; Honkakoski. P.; Stenbäch, F.; Niemitz, M.; Alhava, E.; Pelkonen, O.; Lang, M.A.; Pasanen, M. Cocaine Ndemethylation and the metabolism-related hepatotoxicity can be prevented by cytochrome P450 3A inhibitors. Eur. J. Pharmacol., 1994, 270(1), 35-43.
-
(1994)
Eur. J. Pharmacol
, vol.270
, Issue.1
, pp. 35-43
-
-
Pellinen, P.1
Honkakoski, P.2
Stenbäch, F.3
Niemitz, M.4
Alhava, E.5
Pelkonen, O.6
Lang, M.A.7
Pasanen, M.8
-
317
-
-
20344366514
-
Ndemethylation by mouse liver microsomal cytochrome P450 enzymes
-
Chou, Y.C.; Ueng, Y.F.; Chou, C.Y.; Tien, J.H. Dimemorfan Ndemethylation by mouse liver microsomal cytochrome P450 enzymes. Life Sci., 2005, 77(7), 735-745.
-
(2005)
Life Sci
, vol.77
, Issue.7
, pp. 735-745
-
-
Chou, Y.C.1
Ueng, Y.F.2
Chou, C.Y.3
Tien, J.H.D.4
-
318
-
-
70349142732
-
Inhibition of human CYP2B6-catalyzed bupropion hydroxylation by Ginkgo biloba extract: Effect of terpene trilactones and flavonols
-
Lau, A.J.; Chang, T.K.H. Inhibition of human CYP2B6-catalyzed bupropion hydroxylation by Ginkgo biloba extract: effect of terpene trilactones and flavonols. Drug Metab. Dispos., 2009, 37(9), 1931-1937.
-
(2009)
Drug Metab. Dispos
, vol.37
, Issue.9
, pp. 1931-1937
-
-
Lau, A.J.1
Chang, T.K.H.2
-
319
-
-
0024353692
-
Functional characterization of two cytochrome P-450s within the mouse, male-specific steroid 16α-hydroxylase gene family: Expression in mammalian cells and chimeric proteins
-
Ichikawa, T.; Itakura, T.; Negishi, M. Functional characterization of two cytochrome P-450s within the mouse, male-specific steroid 16α-hydroxylase gene family: expression in mammalian cells and chimeric proteins. Biochemistry, 1989, 28(11), 4779-4784.
-
(1989)
Biochemistry
, vol.28
, Issue.11
, pp. 4779-4784
-
-
Ichikawa, T.1
Itakura, T.2
Negishi, M.3
-
320
-
-
0030885306
-
Selective deficiency of debrisoquine 4-hydroxylase activity in mouse liver microsomes
-
Masubuchi, Y.; Iwasa, T.; Hosokawa, S.; Suzuki, T.; Horie, T.; Imaoka, S.; Funae, Y.; Narimatsu, S. Selective deficiency of debrisoquine 4-hydroxylase activity in mouse liver microsomes. J. Pharmacol. Exp. Ther., 1997, 282(3), 1435-1441.
-
(1997)
J. Pharmacol. Exp. Ther
, vol.282
, Issue.3
, pp. 1435-1441
-
-
Masubuchi, Y.1
Iwasa, T.2
Hosokawa, S.3
Suzuki, T.4
Horie, T.5
Imaoka, S.6
Funae, Y.7
Narimatsu, S.8
-
321
-
-
33745245269
-
Expression, purification, and characterization of mouse CYP2D22
-
Yu, A.M.; Haining, R.L. Expression, purification, and characterization of mouse CYP2D22. Drug Metab. Dispos., 2006, 34(7), 1167-1174.
-
(2006)
Drug Metab. Dispos
, vol.34
, Issue.7
, pp. 1167-1174
-
-
Yu, A.M.1
Haining, R.L.2
-
322
-
-
35348908289
-
Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using Cyp2e1 -/ - mice
-
Ghanayem, B.I.; Hoffler, U. Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using Cyp2e1 -/ - mice. Curr. Drug Metab., 2007, 8(7), 728-749.
-
(2007)
Curr. Drug Metab
, vol.8
, Issue.7
, pp. 728-749
-
-
Ghanayem, B.I.1
Hoffler, U.2
-
323
-
-
0031901889
-
Cytochrome P450 catalyzed oxidation of monochlorobenzene, 1,2- and 1,4-dichlorobenzene in rat, mouse, and human liver microsomes
-
Nedelcheva, V.; Gut, I.; Souček, P.; Frantík, E. Cytochrome P450 catalyzed oxidation of monochlorobenzene, 1,2- and 1,4-dichlorobenzene in rat, mouse, and human liver microsomes. Chem.-Biol. Interact., 1998, 115(1), 53-70.
-
(1998)
Chem.-Biol. Interact
, vol.115
, Issue.1
, pp. 53-70
-
-
Nedelcheva, V.1
Gut, I.2
Souček, P.3
Frantík, E.4
-
324
-
-
1242320311
-
Kinetic factors involved in the metabolism of benzene in mouse lung and liver
-
Sheets, P.; Carlson, G. Kinetic factors involved in the metabolism of benzene in mouse lung and liver. J. Toxicol. Environ. Health A, 2004, 67(5), 421-430.
-
(2004)
J. Toxicol. Environ. Health A
, vol.67
, Issue.5
, pp. 421-430
-
-
Sheets, P.1
Carlson, G.2
-
325
-
-
0027499582
-
Cytochrome P450-related differences between rats and mice in the metabolism of benzene, toluene and trichloroethylene in liver microsomes
-
Nakajima, T.; Wang, R.S.; Elovaara, E.; Park, S.S.; Gelboin, H.V.; Vainio, H. Cytochrome P450-related differences between rats and mice in the metabolism of benzene, toluene and trichloroethylene in liver microsomes. Biochem. Pharmacol., 1992, 45(5), 1079-1085.
-
(1992)
Biochem. Pharmacol
, vol.45
, Issue.5
, pp. 1079-1085
-
-
Nakajima, T.1
Wang, R.S.2
Elovaara, E.3
Park, S.S.4
Gelboin, H.V.5
Vainio, H.6
-
326
-
-
0028239623
-
In vitro biotransformation of 1,1-dichloroethylene by hepatic cytochrome P-450 2E1 in mice
-
Lee, R.P.; Forkert, P.G. In vitro biotransformation of 1,1-dichloroethylene by hepatic cytochrome P-450 2E1 in mice. J. Pharmacol. Exp. Ther., 1994, 270(1), 371-376.
-
(1994)
J. Pharmacol. Exp. Ther
, vol.270
, Issue.1
, pp. 371-376
-
-
Lee, R.P.1
Forkert, P.G.2
-
327
-
-
0037799290
-
In vitro metabolism of styrene to styrene oxide in liver and lung of CYP2E1 knockout mice
-
Carlson, G.P. In vitro metabolism of styrene to styrene oxide in liver and lung of CYP2E1 knockout mice. J. Toxicol. Environ. Health A, 2003, 66(9), 861-869.
-
(2003)
J. Toxicol. Environ. Health A
, vol.66
, Issue.9
, pp. 861-869
-
-
Carlson, G.P.1
-
328
-
-
0026348668
-
Mouse pulmonary cytochrome P-450 naphthalene hydroxylase: CDNA cloning, sequence, and expression in Saccharomyces cerevisiae
-
Ritter, J.K.; Owens, I.S.; Negishi, M.; Nagata, K.; Sheen, Y.Y.; Gillette, J.R.; Sasame, H.A. Mouse pulmonary cytochrome P-450 naphthalene hydroxylase: cDNA cloning, sequence, and expression in Saccharomyces cerevisiae. Biochemistry, 1991, 30(48), 11430-11437.
-
(1991)
Biochemistry
, vol.30
, Issue.48
, pp. 11430-11437
-
-
Ritter, J.K.1
Owens, I.S.2
Negishi, M.3
Nagata, K.4
Sheen, Y.Y.5
Gillette, J.R.6
Sasame, H.A.7
-
329
-
-
0032967333
-
Role of murine cytochrome P-450 2F2 in metabolic activation of naphthalene and metabolism of other xenobiotics
-
Shultz, M.A.; Choudary, P.V.; Buckpitt, A.R. Role of murine cytochrome P-450 2F2 in metabolic activation of naphthalene and metabolism of other xenobiotics. J. Pharmacol. Exp. Ther., 1999, 290(1), 281-288.
-
(1999)
J. Pharmacol. Exp. Ther
, vol.290
, Issue.1
, pp. 281-288
-
-
Shultz, M.A.1
Choudary, P.V.2
Buckpitt, A.R.3
-
330
-
-
0035145702
-
Metabolic capabilities of CYP2F2 with various pulmonary toxicants and its relative abundance in mouse lung subcompartments
-
Shultz, M.A.; Morin, D.; Chang, A.M.; Buckpitt, A. Metabolic capabilities of CYP2F2 with various pulmonary toxicants and its relative abundance in mouse lung subcompartments. J. Pharmacol. Exp. Ther., 2001, 296(2), 510-519.
-
(2001)
J. Pharmacol. Exp. Ther
, vol.296
, Issue.2
, pp. 510-519
-
-
Shultz, M.A.1
Morin, D.2
Chang, A.M.3
Buckpitt, A.4
-
331
-
-
4143076189
-
Bioactivation of 1,1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes
-
Simmonds, A.C.; Reilly, C.A.; Baldwin, R.M.; Ghanayem, B.I.; Lanza, D.L.; Yost, G.S.; Collins, K.S.; Forkert, P.G. Bioactivation of 1,1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes. Drug Metab. Dispos., 2004, 32(9), 1032-1039.
-
(2004)
Drug Metab. Dispos
, vol.32
, Issue.9
, pp. 1032-1039
-
-
Simmonds, A.C.1
Reilly, C.A.2
Baldwin, R.M.3
Ghanayem, B.I.4
Lanza, D.L.5
Yost, G.S.6
Collins, K.S.7
Forkert, P.G.8
-
332
-
-
24944498459
-
Pulmonary bioactivation of trichloroethylene to chloral hydrate: Relative contributions of CYP2E1, CYP2F, and CYP2B1
-
Forkert, P.G.; Baldwin, R.M.; Millen, B.; Lash, L.H.; Putt, D.A.; Shultz, M.A.; Collins, K.S. Pulmonary bioactivation of trichloroethylene to chloral hydrate: relative contributions of CYP2E1, CYP2F, and CYP2B1. Drug Metab. Dispos., 2005, 33(10), 1429-1437.
-
(2005)
Drug Metab. Dispos
, vol.33
, Issue.10
, pp. 1429-1437
-
-
Forkert, P.G.1
Baldwin, R.M.2
Millen, B.3
Lash, L.H.4
Putt, D.A.5
Shultz, M.A.6
Collins, K.S.7
-
333
-
-
0027988797
-
Styrene metabolism by cDNA-expressed human hepatic and pulmonary cytochromes P450
-
Nakajima, T.; Elovaara, E.; Gonzalez, F.J.; Gelboin, H.V.; Raunio, H.; Pelkonen, O.; Vainio, H.; Aoyama, T. Styrene metabolism by cDNA-expressed human hepatic and pulmonary cytochromes P450. Chem. Res. Toxicol., 1994, 7(6), 891-896.
-
(1994)
Chem. Res. Toxicol
, vol.7
, Issue.6
, pp. 891-896
-
-
Nakajima, T.1
Elovaara, E.2
Gonzalez, F.J.3
Gelboin, H.V.4
Raunio, H.5
Pelkonen, O.6
Vainio, H.7
Aoyama, T.8
-
334
-
-
0033058630
-
Biotransformation of coumarin by rodent and human cytochromes P-450: Metabolic basis of tissue-selective toxicity in olfactory mucosa of rats and mice
-
Zhuo, X.; Gu, J.; Zhang, Q.Y.; Spink, D.C.; Kaminsky, L.S.; Ding, X. Biotransformation of coumarin by rodent and human cytochromes P-450: metabolic basis of tissue-selective toxicity in olfactory mucosa of rats and mice. J. Pharmacol. Exp. Ther., 1999, 288(2), 463-471.
-
(1999)
J. Pharmacol. Exp. Ther
, vol.288
, Issue.2
, pp. 463-471
-
-
Zhuo, X.1
Gu, J.2
Zhang, Q.Y.3
Spink, D.C.4
Kaminsky, L.S.5
Ding, X.6
-
335
-
-
2442699046
-
Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase
-
Cheng, J.B.; Levine, M.A.; Bell, N.H.; Mangelsdorf, D.J.; Russell, D.W. Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase. Proc. Natl. Acad. Sci. USA, 2004, 101(20), 7711-7715.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, Issue.20
, pp. 7711-7715
-
-
Cheng, J.B.1
Levine, M.A.2
Bell, N.H.3
Mangelsdorf, D.J.4
Russell, D.W.5
-
336
-
-
77649087361
-
Functional characterization of human and mouse cytochrome P450 2S1 proteins using a bacterial recombinant expression system
-
Abstract 1835
-
Bui, P.; Hankinson, O. Functional characterization of human and mouse cytochrome P450 2S1 proteins using a bacterial recombinant expression system. 45th Annual Meeting of Society of Toxicology, 2006, Abstract 1835.
-
(2006)
45th Annual Meeting of Society of Toxicology
-
-
Bui, P.1
Hankinson, O.2
-
337
-
-
0036799870
-
The nuclear pregnane X receptor: A key regulator of xenobiotic metabolism
-
Kliewer, S.A.; Goodwin, B.; Willson, T.M. The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. Endocr. Rev., 2002, 23(5), 687-702.
-
(2002)
Endocr. Rev
, vol.23
, Issue.5
, pp. 687-702
-
-
Kliewer, S.A.1
Goodwin, B.2
Willson, T.M.3
-
338
-
-
0035860807
-
-/ - mice but not in cerebrotendinous xanthomatosis
-
-/ - mice but not in cerebrotendinous xanthomatosis. J. Biol. Chem., 2001, 276(37), 34579-34585.
-
(2001)
J. Biol. Chem
, vol.276
, Issue.37
, pp. 34579-34585
-
-
Honda, A.1
Salen, G.2
Matsuzaki, Y.3
Batta, A.K.4
Xu, G.5
Leitersdorf, E.6
Tint, G.S.7
Erickson, S.K.8
Tanaka, N.9
Shefer, S.10
-
339
-
-
0141706810
-
Genomic characterization and regulation of CYP3a13: Role of xenobiotics and nuclear receptors
-
Anakk, S.; Kalsotra, A.; Shen, Q.; Vu, M.T.; Staudinger, J.L.; Davies, P.J.A.; Strobel, H.W. Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors. FASEB J., 2003, 17(12), 1736-1738.
-
(2003)
FASEB J
, vol.17
, Issue.12
, pp. 1736-1738
-
-
Anakk, S.1
Kalsotra, A.2
Shen, Q.3
Vu, M.T.4
Staudinger, J.L.5
Davies, P.J.A.6
Strobel, H.W.7
-
340
-
-
0036893593
-
Evaluation of cytochrome P450 probe substrates commonly used by the pharmaceutical industry to study in vitro drug interactions
-
Yuan, R.; Madani, S.; Wei, X.X.; Reynolds, K.; Huang, S.M. Evaluation of cytochrome P450 probe substrates commonly used by the pharmaceutical industry to study in vitro drug interactions. Drug Metab. Dispos., 2002, 30(12), 1311-1319.
-
(2002)
Drug Metab. Dispos
, vol.30
, Issue.12
, pp. 1311-1319
-
-
Yuan, R.1
Madani, S.2
Wei, X.X.3
Reynolds, K.4
Huang, S.M.5
-
341
-
-
0033613935
-
Identification of CYP3A4 as the major enzyme responsible for 25-hydroxylation of 5β-cholestane-3α,7α, 12α-triol in human liver microsomes
-
Furster, C.; Wikvall, K. Identification of CYP3A4 as the major enzyme responsible for 25-hydroxylation of 5β-cholestane-3α,7α, 12α-triol in human liver microsomes. Biochim. Biophys. Acta, 1999, 1437(1), 46-52.
-
(1999)
Biochim. Biophys. Acta
, vol.1437
, Issue.1
, pp. 46-52
-
-
Furster, C.1
Wikvall, K.2
-
342
-
-
0033583336
-
6α-Hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes
-
Araya, Z.; Wikvall, K. 6α-Hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes. Biochim. Biophys. Acta, 1999, 1438(1), 47-54.
-
(1999)
Biochim. Biophys. Acta
, vol.1438
, Issue.1
, pp. 47-54
-
-
Araya, Z.1
Wikvall, K.2
-
343
-
-
13644266845
-
Novel pathways of bile acid metabolism involving CYP3A4
-
Bodin, K.; Lindbom, U.; Diczfalusy, U. Novel pathways of bile acid metabolism involving CYP3A4. Biochim. Biophys. Acta, 2005, 1687(1-3), 84-93.
-
(2005)
Biochim. Biophys. Acta
, vol.1687
, Issue.1-3
, pp. 84-93
-
-
Bodin, K.1
Lindbom, U.2
Diczfalusy, U.3
-
344
-
-
0033779317
-
Cytochrome P450-dependent renal arachidonic acid metabolism in desoxycorticosterone acetate-salt hypertensive mice
-
Honeck, H.; Gross, V.; Erdmann, B.; Kärgel, E.; Neunaber, R.; Milia, A.F.; Schneider, W.; Luft, F.C.; Schunck, W.H. Cytochrome P450-dependent renal arachidonic acid metabolism in desoxycorticosterone acetate-salt hypertensive mice. Hypertension, 2000, 36(4), 610-616.
-
(2000)
Hypertension
, vol.36
, Issue.4
, pp. 610-616
-
-
Honeck, H.1
Gross, V.2
Erdmann, B.3
Kärgel, E.4
Neunaber, R.5
Milia, A.F.6
Schneider, W.7
Luft, F.C.8
Schunck, W.H.9
-
345
-
-
13844309746
-
Regulation and inhibition of arachidonic acid ω-hydroxylases and 20-HETE formation
-
Kroetz, D.L.; Xu, F. Regulation and inhibition of arachidonic acid ω-hydroxylases and 20-HETE formation. Annu. Rev. Pharmacol. Toxicol., 2005, 45, 413-438.
-
(2005)
Annu. Rev. Pharmacol. Toxicol
, vol.45
, pp. 413-438
-
-
Kroetz, D.L.1
Xu, F.2
-
346
-
-
0027459403
-
Characterization of a cDNA encoding a human kidney, cytochrome P-450 4A fatty acid ω-hydroxylase and the cognate enzyme expressed in Escherichia coli
-
Palmer, C.N.; Richardson, T.H.; Griffin, K.J.; Hsu, M.H.; Muerhoff, A.S.; Clark, J.E.; Johnson, E.F. Characterization of a cDNA encoding a human kidney, cytochrome P-450 4A fatty acid ω-hydroxylase and the cognate enzyme expressed in Escherichia coli. Biochim. Biophys. Acta, 1993, 1172(1-2), 161-166.
-
(1993)
Biochim. Biophys. Acta
, vol.1172
, Issue.1-2
, pp. 161-166
-
-
Palmer, C.N.1
Richardson, T.H.2
Griffin, K.J.3
Hsu, M.H.4
Muerhoff, A.S.5
Clark, J.E.6
Johnson, E.F.7
-
347
-
-
0343471515
-
Mutagenic activation of urinary bladder carcinogens by CYP4B1 and the presence of CYP4B1 in bladder mucosa
-
Imaoka, S.; Yoneda, Y.; Matsuda, T.; Degawa, M.; Fukushima, S.; Funae, Y. Mutagenic activation of urinary bladder carcinogens by CYP4B1 and the presence of CYP4B1 in bladder mucosa. Biochem. Pharmacol., 1997, 54(6), 677-683.
-
(1997)
Biochem. Pharmacol
, vol.54
, Issue.6
, pp. 677-683
-
-
Imaoka, S.1
Yoneda, Y.2
Matsuda, T.3
Degawa, M.4
Fukushima, S.5
Funae, Y.6
-
348
-
-
0034810603
-
A transgenic mouse expressing human CYP4B1 in the liver
-
Imaoka, S.; Hayashi, K.; Hiroi, T.; Yabusaki, Y.; Kamataki, T.; Funae, Y. A transgenic mouse expressing human CYP4B1 in the liver. Biochem. Biophys. Res. Commun., 2001, 284(3), 757-762.
-
(2001)
Biochem. Biophys. Res. Commun
, vol.284
, Issue.3
, pp. 757-762
-
-
Imaoka, S.1
Hayashi, K.2
Hiroi, T.3
Yabusaki, Y.4
Kamataki, T.5
Funae, Y.6
-
349
-
-
0032530321
-
Identification of a meander region proline residue critical for heme binding to cytochrome P450: Implications for the catalytic function of human CYP4B1
-
Zheng, Y.M.; Fisher, M.B.; Yokotani, N.; Fujii-Kuriyama, Y.; Rettie, A.E. Identification of a meander region proline residue critical for heme binding to cytochrome P450: implications for the catalytic function of human CYP4B1. Biochemistry, 1998, 37(37), 12847- 12851.
-
(1998)
Biochemistry
, vol.37
, Issue.37
, pp. 12847-12851
-
-
Zheng, Y.M.1
Fisher, M.B.2
Yokotani, N.3
Fujii-Kuriyama, Y.4
Rettie, A.E.5
-
350
-
-
0034597678
-
CYP4B1 is a possible risk factor for bladder cancer in humans
-
Imaoka, S.; Yoneda, Y.; Sugimoto, T.; Ikemoto, S.; Hiroi, T.; Yamamoto, K.; Nakatani, T.; Funae, Y. CYP4B1 is a possible risk factor for bladder cancer in humans. Biochem. Biophys. Res. Commun., 2000, 277(3), 776-780.
-
(2000)
Biochem. Biophys. Res. Commun
, vol.277
, Issue.3
, pp. 776-780
-
-
Imaoka, S.1
Yoneda, Y.2
Sugimoto, T.3
Ikemoto, S.4
Hiroi, T.5
Yamamoto, K.6
Nakatani, T.7
Funae, Y.8
-
351
-
-
0017156667
-
Sodium periodate, sodium chlorite, and organic hydroperoxides as hydroxylating agents in steroid hydroxylation reactions catalyzed by adrenocortical microsomal and mitochondrial cytochrome P450
-
Gustafsson, J.Å.; Hrycay, E.G.; Ernster, L. Sodium periodate, sodium chlorite, and organic hydroperoxides as hydroxylating agents in steroid hydroxylation reactions catalyzed by adrenocortical microsomal and mitochondrial cytochrome P450. Arch. Biochem. Biophys., 1976, 174(2), 440-453.
-
(1976)
Arch. Biochem. Biophys
, vol.174
, Issue.2
, pp. 440-453
-
-
Gustafsson, J.A.1
Hrycay, E.G.2
Ernster, L.3
-
352
-
-
4444312707
-
Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids
-
Kalsotra, A.; Turman, C.M.; Kikuta, Y.; Strobel, H.W. Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids. Toxicol. Appl. Pharmacol., 2004, 199(3), 295-304.
-
(2004)
Toxicol. Appl. Pharmacol
, vol.199
, Issue.3
, pp. 295-304
-
-
Kalsotra, A.1
Turman, C.M.2
Kikuta, Y.3
Strobel, H.W.4
-
353
-
-
0032213301
-
Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4
-
Jin, R.; Koop, D.R.; Raucy, J.L.; Lasker, J.M. Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4. Arch. Biochem. Biophys., 1998, 359(1), 89-98.
-
(1998)
Arch. Biochem. Biophys
, vol.359
, Issue.1
, pp. 89-98
-
-
Jin, R.1
Koop, D.R.2
Raucy, J.L.3
Lasker, J.M.4
-
355
-
-
0347683479
-
A novel human cytochrome P450, CYP26C1, involved in metabolism of 9-cis and all-trans isomers of retinoic acid
-
Taimi, M.; Helvig, C.; Wisniewski, J.; Ramshaw, H.; White, J.; Amad, M.; Korczak, B.; Petkovich, M. A novel human cytochrome P450, CYP26C1, involved in metabolism of 9-cis and all-trans isomers of retinoic acid. J. Biol. Chem., 2004, 279(1), 77-85.
-
(2004)
J. Biol. Chem
, vol.279
, Issue.1
, pp. 77-85
-
-
Taimi, M.1
Helvig, C.2
Wisniewski, J.3
Ramshaw, H.4
White, J.5
Amad, M.6
Korczak, B.7
Petkovich, M.8
-
356
-
-
0024211692
-
A comparative study of 1-substituted imidazole and 1,2,4-triazole antifungal compounds as inhibitors of testosterone hydroxylations catalysed by mouse hepatic microsomal cytochromes P-450
-
Ballard, S.A.; Lodola, A.; Tarbit, M.H. A comparative study of 1-substituted imidazole and 1,2,4-triazole antifungal compounds as inhibitors of testosterone hydroxylations catalysed by mouse hepatic microsomal cytochromes P-450. Biochem. Pharmacol., 1988, 37(24), 4643-4651.
-
(1988)
Biochem. Pharmacol
, vol.37
, Issue.24
, pp. 4643-4651
-
-
Ballard, S.A.1
Lodola, A.2
Tarbit, M.H.3
-
357
-
-
0027537370
-
Differential inhibition of coumarin 7-hydroxylase activity in mouse and human liver microsomes
-
Mäenpää, J.; Sigusch, H.; Raunio, H.; Syngelmä, T.; Vuorela, P.; Vuorela, H.; Pelkonen, O. Differential inhibition of coumarin 7-hydroxylase activity in mouse and human liver microsomes. Biochem. Pharmacol., 1993, 45(5), 1035-1042.
-
(1993)
Biochem. Pharmacol
, vol.45
, Issue.5
, pp. 1035-1042
-
-
Mäenpää, J.1
Sigusch, H.2
Raunio, H.3
Syngelmä, T.4
Vuorela, P.5
Vuorela, H.6
Pelkonen, O.7
-
358
-
-
1242338755
-
Cyp1a2 protects against reactive oxygen production in mouse liver microsomes
-
Shertzer, H.G.; Clay, C.D.; Genter, M.B.; Schneider, S.N.; Nebert, D.W.; Dalton, T.P. Cyp1a2 protects against reactive oxygen production in mouse liver microsomes. Free Rad. Biol. Med., 2004, 36(5), 605-617.
-
(2004)
Free Rad. Biol. Med
, vol.36
, Issue.5
, pp. 605-617
-
-
Shertzer, H.G.1
Clay, C.D.2
Genter, M.B.3
Schneider, S.N.4
Nebert, D.W.5
Dalton, T.P.6
-
359
-
-
38649091964
-
Different modes of inhibition of mouse Cyp2a5 and rat CYP2A3 by the food-derived 8-methoxypsoralen
-
Visoni, S.; Meireles, N.; Monteiro, L.; Rossini, A.; Pinto, L.F.R. Different modes of inhibition of mouse Cyp2a5 and rat CYP2A3 by the food-derived 8-methoxypsoralen. Food Chem. Toxicol., 2008, 46(3), 1190-1195.
-
(2008)
Food Chem. Toxicol
, vol.46
, Issue.3
, pp. 1190-1195
-
-
Visoni, S.1
Meireles, N.2
Monteiro, L.3
Rossini, A.4
Pinto, L.F.R.5
-
360
-
-
0028900417
-
The inhibition of CYP enzymes in mouse and human liver by pilocarpine
-
Kimonen, T.; Juvonen, R.O.; Alhava, E.; Pasanen, M. The inhibition of CYP enzymes in mouse and human liver by pilocarpine. Br. J. Pharmacol., 1995, 114(4), 832-836.
-
(1995)
Br. J. Pharmacol
, vol.114
, Issue.4
, pp. 832-836
-
-
Kimonen, T.1
Juvonen, R.O.2
Alhava, E.3
Pasanen, M.4
-
361
-
-
0036971001
-
Moricizine, an antiarrhythmic agent, as a potent inhibitor of hepatic microsomal CYP1A
-
Konishi, H.; Morita, K.; Minouchi, T.; Yamaji, A. Moricizine, an antiarrhythmic agent, as a potent inhibitor of hepatic microsomal CYP1A. Pharmacology, 2002, 66(4), 190-198.
-
(2002)
Pharmacology
, vol.66
, Issue.4
, pp. 190-198
-
-
Konishi, H.1
Morita, K.2
Minouchi, T.3
Yamaji, A.4
-
362
-
-
0032804346
-
Metabolism-based polycyclic aromatic acetylene inhibition of CYP1B1 in 10T1/2 cells potentiates aryl hydrocarbon receptor activity
-
Alexander, D.L.; Zhang, L.; Foroozesh, M.; Alworth, W.L.; Jefcoate, C.R. Metabolism-based polycyclic aromatic acetylene inhibition of CYP1B1 in 10T1/2 cells potentiates aryl hydrocarbon receptor activity. Toxicol. Appl. Pharmacol., 1999, 161(2), 123-139.
-
(1999)
Toxicol. Appl. Pharmacol
, vol.161
, Issue.2
, pp. 123-139
-
-
Alexander, D.L.1
Zhang, L.2
Foroozesh, M.3
Alworth, W.L.4
Jefcoate, C.R.5
-
363
-
-
0034666699
-
A transgenic mouse expressing human CYP1A2 in the pancreas
-
Ueno, T.; Tamura, S.; Frels, W.I.; Shou, M.; Gonzalez, F.J.; Kimura, S. A transgenic mouse expressing human CYP1A2 in the pancreas. Biochem. Pharmacol., 2000, 60(6), 857-863.
-
(2000)
Biochem. Pharmacol
, vol.60
, Issue.6
, pp. 857-863
-
-
Ueno, T.1
Tamura, S.2
Frels, W.I.3
Shou, M.4
Gonzalez, F.J.5
Kimura, S.6
-
364
-
-
0030974919
-
Mechanism-based inactivation of mouse hepatic cytochrome P4502B enzymes by amine metabolites of musk xylene
-
Lehman-McKeeman, L.D.; Johnson, D.R.; Caudill, D.; Stuard, S.B. Mechanism-based inactivation of mouse hepatic cytochrome P4502B enzymes by amine metabolites of musk xylene. Drug Metab. Dispos., 1997, 25(3), 384-389.
-
(1997)
Drug Metab. Dispos
, vol.25
, Issue.3
, pp. 384-389
-
-
Lehman-McKeeman, L.D.1
Johnson, D.R.2
Caudill, D.3
Stuard, S.B.4
-
365
-
-
0028836093
-
Oxidation of tolualdehydes to toluic acids catalyzed by cytochrome P450-dependent aldehyde oxygenase in the mouse liver
-
Watanabe, K.; Matsunaga, T.; Yamamoto, I.; Yashimura, H. Oxidation of tolualdehydes to toluic acids catalyzed by cytochrome P450-dependent aldehyde oxygenase in the mouse liver. Drug Metab. Dispos., 1995, 23(2), 261-265.
-
(1995)
Drug Metab. Dispos
, vol.23
, Issue.2
, pp. 261-265
-
-
Watanabe, K.1
Matsunaga, T.2
Yamamoto, I.3
Yashimura, H.4
-
366
-
-
0033695149
-
Characterization of cytochrome P450 enzymes involved in drug oxidations in mouse intestinal microsomes
-
Emoto, C.; Yamazaki, H.; Yamasaki, S.; Shimada, N.; Nakajima, M.; Yokoi, T. Characterization of cytochrome P450 enzymes involved in drug oxidations in mouse intestinal microsomes. Xenobiotica, 2000, 30(10), 943-953.
-
(2000)
Xenobiotica
, vol.30
, Issue.10
, pp. 943-953
-
-
Emoto, C.1
Yamazaki, H.2
Yamasaki, S.3
Shimada, N.4
Nakajima, M.5
Yokoi, T.6
-
367
-
-
36749009685
-
In silico and in vitro pharmacogenetic analysis in mice
-
Guo, V.; Lu, P.; Farrell, E.; Zhang, X.; Weller, P.; Monshouwer, M.; Wang, J.; Liao, G.; Zhang, Z.; Hu, S.; Allard, J.; Shafer, S.; Usuka, J.; Peltz, G. In silico and in vitro pharmacogenetic analysis in mice. Proc. Natl. Acad. Sci. USA, 2007, 104(45), 17735-17740.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, Issue.45
, pp. 17735-17740
-
-
Guo, V.1
Lu, P.2
Farrell, E.3
Zhang, X.4
Weller, P.5
Monshouwer, M.6
Wang, J.7
Liao, G.8
Zhang, Z.9
Hu, S.10
Allard, J.11
Shafer, S.12
Usuka, J.13
Peltz, G.14
-
368
-
-
27144434397
-
Profiling cytochrome P450 expression in ovarian cancer: Identification of prognostic markers
-
Downie, D.; McFadyen, M.C.E.; Rooney, P.H.; Cruickshank, M.E.; Parkin, D.E.; Miller, I.D.; Telfer, C.; Melvin, W.T.; Murray, G.I. Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers. Clin. Cancer Res., 2005, 11(20), 7369-7375.
-
(2005)
Clin. Cancer Res
, vol.11
, Issue.20
, pp. 7369-7375
-
-
Downie, D.1
McFadyen, M.C.E.2
Rooney, P.H.3
Cruickshank, M.E.4
Parkin, D.E.5
Miller, I.D.6
Telfer, C.7
Melvin, W.T.8
Murray, G.I.9
-
369
-
-
20444445398
-
-
Vidal, J.D.; VandeVoort, C.A.; Marcus, C.B.; Lazarewicz, N.R.; Conley, A.J. 2,3,7,8-tetrachlorodibenzo-p-dioxin induces CYP1B1 expression in human luteinized granulosa cells. Arch. Biochem. Biophys., 2005, 439(1), 53-60.
-
Vidal, J.D.; VandeVoort, C.A.; Marcus, C.B.; Lazarewicz, N.R.; Conley, A.J. 2,3,7,8-tetrachlorodibenzo-p-dioxin induces CYP1B1 expression in human luteinized granulosa cells. Arch. Biochem. Biophys., 2005, 439(1), 53-60.
-
-
-
-
370
-
-
84925567195
-
-
Deo, A.K. Hepatic microsomal bile acid biotransformation: identification of metabolites and cytochrome P450 enzymes involved. Ph.D. Thesis, 2009, The University of British Columbia, British Columbia, Canada.
-
Deo, A.K. Hepatic microsomal bile acid biotransformation: identification of metabolites and cytochrome P450 enzymes involved. Ph.D. Thesis, 2009, The University of British Columbia, British Columbia, Canada.
-
-
-
-
371
-
-
0034685779
-
Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands
-
Moore, L.B.; Parks, D.J.; Jones, S.A.; Bledsoe, R.K.; Consler, T.G.; Stimmel, J.B.; Goodwin, B.; Liddle, C.; Blanchard, S.G.; Willson, T.M.; Collins, J.L.; Kliewer, S.A. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands. J. Biol. Chem., 2000, 275(20), 15122-15127.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.20
, pp. 15122-15127
-
-
Moore, L.B.1
Parks, D.J.2
Jones, S.A.3
Bledsoe, R.K.4
Consler, T.G.5
Stimmel, J.B.6
Goodwin, B.7
Liddle, C.8
Blanchard, S.G.9
Willson, T.M.10
Collins, J.L.11
Kliewer, S.A.12
-
372
-
-
23044477294
-
The ratio of constitutive androstane receptor to pregnane X receptor determines the activity of guggulsterone against the Cyp2b10 promoter
-
Ding, X.; Staudinger, J.L. The ratio of constitutive androstane receptor to pregnane X receptor determines the activity of guggulsterone against the Cyp2b10 promoter. J. Pharmacol. Exp. Ther., 2005, 314(1), 120-127.
-
(2005)
J. Pharmacol. Exp. Ther
, vol.314
, Issue.1
, pp. 120-127
-
-
Ding, X.1
Staudinger, J.L.2
-
373
-
-
34447100166
-
Enhancer elements in the mouse CYP1A2 gene: A comparative sequencing among different inbred mouse strains
-
Mikhailova, O.N.; Gulyaeva, L.F.; Filipenko, M.L.; Kaledin, V.I. Enhancer elements in the mouse CYP1A2 gene: a comparative sequencing among different inbred mouse strains. Mutat. Res., 2007, 632(1-2), 99-103.
-
(2007)
Mutat. Res
, vol.632
, Issue.1-2
, pp. 99-103
-
-
Mikhailova, O.N.1
Gulyaeva, L.F.2
Filipenko, M.L.3
Kaledin, V.I.4
-
374
-
-
0038768712
-
Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
-
Denison, M.S.; Nagy, S.R. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol., 2003, 43, 309-334.
-
(2003)
Annu. Rev. Pharmacol. Toxicol
, vol.43
, pp. 309-334
-
-
Denison, M.S.1
Nagy, S.R.2
-
375
-
-
33646674486
-
CYP1A in TCDD and in physiology-with particular reference to CYP dependent arachidonic acid metabolism and other endogenous substrates
-
Rifkind, A.B. CYP1A in TCDD and in physiology-with particular reference to CYP dependent arachidonic acid metabolism and other endogenous substrates. Drug Metab. Rev., 2006, 38(1-2), 291-335.
-
(2006)
Drug Metab. Rev
, vol.38
, Issue.1-2
, pp. 291-335
-
-
Rifkind, A.B.1
-
376
-
-
34447530842
-
An aryl hydrocarbon receptor odyssey to the shores of toxicology: The Deichmann Lecture, International Congress of Toxicology-XI
-
Okey, A.B. An aryl hydrocarbon receptor odyssey to the shores of toxicology: the Deichmann Lecture, International Congress of Toxicology-XI. Toxicol. Sci., 2007, 98(1), 5-38.
-
(2007)
Toxicol. Sci
, vol.98
, Issue.1
, pp. 5-38
-
-
Okey, A.B.1
-
377
-
-
35548946775
-
Evidence for an aryl hydrocarbon receptor-mediated cytochrome P450 autoregulatory pathway
-
Chiaro, C.R.; Patel, R.D.; Marcus, C.B.; Perdew, G.H. Evidence for an aryl hydrocarbon receptor-mediated cytochrome P450 autoregulatory pathway. Mol. Pharmacol., 2007, 72(5), 1369-1379.
-
(2007)
Mol. Pharmacol
, vol.72
, Issue.5
, pp. 1369-1379
-
-
Chiaro, C.R.1
Patel, R.D.2
Marcus, C.B.3
Perdew, G.H.4
-
378
-
-
0036156514
-
Identification of a novel dioxin-inducible cytochrome P450
-
Rivera, S.P.; Saarikoski, S.T.; Hankinson, O. Identification of a novel dioxin-inducible cytochrome P450. Mol. Pharmacol., 2002, 61(2), 255-259.
-
(2002)
Mol. Pharmacol
, vol.61
, Issue.2
, pp. 255-259
-
-
Rivera, S.P.1
Saarikoski, S.T.2
Hankinson, O.3
-
379
-
-
15744390146
-
Regulation of the Cyp2a5 gene involves an aryl hydrocarbon receptor-dependent pathway
-
Arpiainen, S.; Raffalli-Mathieu, F.; Lang, M.A.; Pelkonen, O.; Hakkola, J. Regulation of the Cyp2a5 gene involves an aryl hydrocarbon receptor-dependent pathway. Mol. Pharmacol., 2005, 67(4), 1325-1333.
-
(2005)
Mol. Pharmacol
, vol.67
, Issue.4
, pp. 1325-1333
-
-
Arpiainen, S.1
Raffalli-Mathieu, F.2
Lang, M.A.3
Pelkonen, O.4
Hakkola, J.5
-
380
-
-
17844390622
-
Localization of cytochrome P450 CYP2S1 expression in human tissues by in situ hybridization and immunohistochemistry
-
Saarikoski, S.T.; Wikman, H.A.L.; Smith, G.; Wolff, C.H.J.; Husgafvel-Pursianen, K. Localization of cytochrome P450 CYP2S1 expression in human tissues by in situ hybridization and immunohistochemistry. J. Histochem. Cytochem., 2005, 53(5), 549-556.
-
(2005)
J. Histochem. Cytochem
, vol.53
, Issue.5
, pp. 549-556
-
-
Saarikoski, S.T.1
Wikman, H.A.L.2
Smith, G.3
Wolff, C.H.J.4
Husgafvel-Pursianen, K.5
-
381
-
-
33845937674
-
-
Medina-Diaz, I.M.; Arteaga-Illán, G.; Bermudez de León, M.; Cisneros, B.; Sierra-Santoyo, A.; Vega, L.; Gonzalez, F.J.; Elizondo, G. Pregnane X receptor-dependent induction of the CYP3A4 gene by o,p'-1,1,1,-trichloro-2,2-bis-(p-chlorophenyl) ethane. Drug Metab. Dispos., 2007, 35(1), 95-102.
-
Medina-Diaz, I.M.; Arteaga-Illán, G.; Bermudez de León, M.; Cisneros, B.; Sierra-Santoyo, A.; Vega, L.; Gonzalez, F.J.; Elizondo, G. Pregnane X receptor-dependent induction of the CYP3A4 gene by o,p'-1,1,1,-trichloro-2,2-bis-(p-chlorophenyl) ethane. Drug Metab. Dispos., 2007, 35(1), 95-102.
-
-
-
-
382
-
-
24944446096
-
Comparison of TCDD and PCB CYP1A induction sensitivities in fresh hepatocytes from human donors, Sprague-Dawley rats, and rhesus monkeys and HepG2 cells
-
Silkworth, J.B.; Koganti, A.; Illouz, K.; Possolo, A.; Zhao, M.; Hamilton, S.B. Comparison of TCDD and PCB CYP1A induction sensitivities in fresh hepatocytes from human donors, Sprague-Dawley rats, and rhesus monkeys and HepG2 cells. Toxicol. Sci., 2005, 87(2), 508-519.
-
(2005)
Toxicol. Sci
, vol.87
, Issue.2
, pp. 508-519
-
-
Silkworth, J.B.1
Koganti, A.2
Illouz, K.3
Possolo, A.4
Zhao, M.5
Hamilton, S.B.6
-
383
-
-
0030861704
-
Aryl hydrocarbon receptor-dependent induction of Cyp1a1 by bilirubin in mouse hepatoma hepa 1c1c7 cells
-
Sinal, C.J.; Bend, J.R. Aryl hydrocarbon receptor-dependent induction of Cyp1a1 by bilirubin in mouse hepatoma hepa 1c1c7 cells. Mol. Pharmacol., 1997, 52(4), 590-599.
-
(1997)
Mol. Pharmacol
, vol.52
, Issue.4
, pp. 590-599
-
-
Sinal, C.J.1
Bend, J.R.2
-
384
-
-
34547735466
-
Polychlorinated biphenyl exposure and CYP19 gene regulation in testicular and adrenocortical cell lines
-
Li, L.A. Polychlorinated biphenyl exposure and CYP19 gene regulation in testicular and adrenocortical cell lines. Toxicol. In Vitro, 2007, 21(6), 1087-1094.
-
(2007)
Toxicol. In Vitro
, vol.21
, Issue.6
, pp. 1087-1094
-
-
Li, L.A.1
-
385
-
-
0028235721
-
Polychlorinated biphenyls (PCBs): Environmental impact, biochemical and toxic responses, and implications for risk assessment
-
Safe, S.H. Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. Crit. Rev. Toxicol., 1994, 24(2), 87-149.
-
(1994)
Crit. Rev. Toxicol
, vol.24
, Issue.2
, pp. 87-149
-
-
Safe, S.H.1
-
386
-
-
0037440970
-
Antagonism of aryl hydrocarbon receptor-dependent induction of CYP1A1 and inhibition of IgM expression by di-ortho-substituted polychlorinated biphenyls
-
Suh, J.; Kang, J.S.; Yang, K.H.; Kaminski, N.E. Antagonism of aryl hydrocarbon receptor-dependent induction of CYP1A1 and inhibition of IgM expression by di-ortho-substituted polychlorinated biphenyls. Toxicol. Appl. Pharmacol., 2003, 187(1), 11-21.
-
(2003)
Toxicol. Appl. Pharmacol
, vol.187
, Issue.1
, pp. 11-21
-
-
Suh, J.1
Kang, J.S.2
Yang, K.H.3
Kaminski, N.E.4
-
387
-
-
0026046412
-
-
Bjeldanes, L.F.; Kim, J.Y.; Grose, K.R.; Bartholomew, J.C.; Bradfield, C.A. Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Proc. Natl. Acad. Sci. USA, 1991, 88(21), 9543-9547.
-
Bjeldanes, L.F.; Kim, J.Y.; Grose, K.R.; Bartholomew, J.C.; Bradfield, C.A. Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Proc. Natl. Acad. Sci. USA, 1991, 88(21), 9543-9547.
-
-
-
-
388
-
-
0032544183
-
Activation of the Ah receptor by tryptophan and tryptophan metabolites
-
Heath-Pagliuso, S.; Rogers, W.J.; Tullis, K.; Seidel, S.D.; Cenijn, P.H.; Brouwer, A.; Denison, M.S. Activation of the Ah receptor by tryptophan and tryptophan metabolites. Biochemistry, 1998, 37(33), 11508-11515.
-
(1998)
Biochemistry
, vol.37
, Issue.33
, pp. 11508-11515
-
-
Heath-Pagliuso, S.1
Rogers, W.J.2
Tullis, K.3
Seidel, S.D.4
Cenijn, P.H.5
Brouwer, A.6
Denison, M.S.7
-
389
-
-
0034326289
-
Regulation of CYP1A1 transcription via the metabolism of the tryptophan-derived 6-formylindolo[3,2-b]carbazole
-
Wei, Y.D., Bergander, L.; Rannug, U.; Rannug, A. Regulation of CYP1A1 transcription via the metabolism of the tryptophan-derived 6-formylindolo[3,2-b]carbazole. Arch. Biochem. Biophys., 2000, 383(1), 99-107.
-
(2000)
Arch. Biochem. Biophys
, vol.383
, Issue.1
, pp. 99-107
-
-
Wei, Y.D.1
Bergander, L.2
Rannug, U.3
Rannug, A.4
-
390
-
-
11144355731
-
Aryl hydrocarbon receptor-mediated induction of microsomal drug-metabolizing enzyme activity by indirubin and indigo
-
Sugihara, K.; Kitamura, S.; Yamada, T.; Okayama, T.; Ohta, S.; Yamashita, K.; Yasuda, M.; Fujii-Kuriyama, Y.; Saeki, K.; Matsui, S.; Matsuda, T. Aryl hydrocarbon receptor-mediated induction of microsomal drug-metabolizing enzyme activity by indirubin and indigo. Biochem. Biophys. Res. Commun., 2004, 318(2), 571-578.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.318
, Issue.2
, pp. 571-578
-
-
Sugihara, K.1
Kitamura, S.2
Yamada, T.3
Okayama, T.4
Ohta, S.5
Yamashita, K.6
Yasuda, M.7
Fujii-Kuriyama, Y.8
Saeki, K.9
Matsui, S.10
Matsuda, T.11
-
391
-
-
0032570685
-
Characterization of the mouse Cyp1B1 gene. Identification of an enhancer region that directs aryl hydrocarbon receptor-mediated constitutive and induced expression
-
Zhang, L.; Savas, Ü.; Alexander, D.L.; Jefcoate, C.R. Characterization of the mouse Cyp1B1 gene. Identification of an enhancer region that directs aryl hydrocarbon receptor-mediated constitutive and induced expression. J. Biol. Chem., 1998, 273(9), 5174-5183.
-
(1998)
J. Biol. Chem
, vol.273
, Issue.9
, pp. 5174-5183
-
-
Zhang, L.1
Savas, U.2
Alexander, D.L.3
Jefcoate, C.R.4
-
392
-
-
0033535843
-
Lipoxin A4: A new class of ligand for the Ah receptor
-
Schaldach, C.M.; Riby, J.; Bjeldanes, L.F. Lipoxin A4: a new class of ligand for the Ah receptor. Biochemistry, 1999, 38(23), 7594-7600.
-
(1999)
Biochemistry
, vol.38
, Issue.23
, pp. 7594-7600
-
-
Schaldach, C.M.1
Riby, J.2
Bjeldanes, L.F.3
-
393
-
-
0034897230
-
Activation of the Ah receptor signaling pathway by prostaglandins
-
Seidel, S.D.; Winters, G.M.; Rogers, W.J.; Ziccardi, M.H.; Li, V.; Keser, B.; Denison, M.S. Activation of the Ah receptor signaling pathway by prostaglandins. J. Biochem. Mol. Toxicol., 2001, 15(4), 187-196.
-
(2001)
J. Biochem. Mol. Toxicol
, vol.15
, Issue.4
, pp. 187-196
-
-
Seidel, S.D.1
Winters, G.M.2
Rogers, W.J.3
Ziccardi, M.H.4
Li, V.5
Keser, B.6
Denison, M.S.7
-
394
-
-
0842303036
-
-
Lin, P.; Chang, Y.C.; Chen, C.H.; Yang, W.J.; Cheng, Y.H.; Chang, L.W. A comparative study on the effects of 2,3,7,8,-tetrachlorodibenzo-p-dioxin, polychlorinated biphenyl 126 and estrogen in human bronchial epithelial cells. Toxicol. Appl. Pharmacol., 2004, 195(1), 83-91.
-
Lin, P.; Chang, Y.C.; Chen, C.H.; Yang, W.J.; Cheng, Y.H.; Chang, L.W. A comparative study on the effects of 2,3,7,8,-tetrachlorodibenzo-p-dioxin, polychlorinated biphenyl 126 and estrogen in human bronchial epithelial cells. Toxicol. Appl. Pharmacol., 2004, 195(1), 83-91.
-
-
-
-
395
-
-
0027443904
-
Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture
-
Abdel-Razzak, Z.; Loyer, P.; Fautrel, A.; Gauthier, J.C.; Corcos, L.; Turlin, B.; Beaune, P.; Guillouzo, A. Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture. Mol. Pharmacol., 1993, 44(4), 707-715.
-
(1993)
Mol. Pharmacol
, vol.44
, Issue.4
, pp. 707-715
-
-
Abdel-Razzak, Z.1
Loyer, P.2
Fautrel, A.3
Gauthier, J.C.4
Corcos, L.5
Turlin, B.6
Beaune, P.7
Guillouzo, A.8
-
396
-
-
0038699442
-
Induction and suppression of cytochrome P450 isoenzymes and generation of oxygen radicals by procymidone in liver, kidney and lung of CD1 mice
-
Sapone, A.; Affatato, A.; Canistro, D.; Broccoli, M.; Trespidi, S.; Pozzetti, L.; Biagi, G.L.; Cantelli-Forti, G.; Paolini, M. Induction and suppression of cytochrome P450 isoenzymes and generation of oxygen radicals by procymidone in liver, kidney and lung of CD1 mice. Mutat. Res., 2003, 527(1-2), 67-80.
-
(2003)
Mutat. Res
, vol.527
, Issue.1-2
, pp. 67-80
-
-
Sapone, A.1
Affatato, A.2
Canistro, D.3
Broccoli, M.4
Trespidi, S.5
Pozzetti, L.6
Biagi, G.L.7
Cantelli-Forti, G.8
Paolini, M.9
-
397
-
-
33750885465
-
Expression of xenobiotic metabolizing enzymes in different lung compartments of smokers and non-smokers
-
Thum, T.; Erpenbeck, V.J.; Moeller, J.; Hohlfeld, J.; Krug, N.; Borlak, J. Expression of xenobiotic metabolizing enzymes in different lung compartments of smokers and non-smokers. Environ. Health Perspect., 2006, 114(11), 1655-1661.
-
(2006)
Environ. Health Perspect
, vol.114
, Issue.11
, pp. 1655-1661
-
-
Thum, T.1
Erpenbeck, V.J.2
Moeller, J.3
Hohlfeld, J.4
Krug, N.5
Borlak, J.6
-
398
-
-
68149164709
-
The role of CYP26 enzymes in retinoic acid clearance
-
Thatcher, J.E.; Isoherranen, N. The role of CYP26 enzymes in retinoic acid clearance. Expert Opin. Drug Metab. Toxicol., 2009, 5(8), 875-886.
-
(2009)
Expert Opin. Drug Metab. Toxicol
, vol.5
, Issue.8
, pp. 875-886
-
-
Thatcher, J.E.1
Isoherranen, N.2
-
399
-
-
0031807287
-
P450 isoforms in a murine macrophage cell line, RAW264.7, and changes in the levels of P450 isoforms by treatment of cells with lipopolysaccharide and interferon-γ
-
Nakamura, M.; Imaoka, S.; Amano, F.; Funae, Y. P450 isoforms in a murine macrophage cell line, RAW264.7, and changes in the levels of P450 isoforms by treatment of cells with lipopolysaccharide and interferon-γ. Biochim. Biophys. Acta, 1998, 1385(1), 101-106.
-
(1998)
Biochim. Biophys. Acta
, vol.1385
, Issue.1
, pp. 101-106
-
-
Nakamura, M.1
Imaoka, S.2
Amano, F.3
Funae, Y.4
-
400
-
-
3142665438
-
Mechanisms of cholesterol and sterol regulatory element binding protein regulation of the sterol 12α- hydroxylase gene (CYP8B1)
-
Yang, Y.; Eggertsen, G.; Gåfvels, M.; Andersson, U.; Einarsson, C.; Björkhem, I.; Chiang, J.Y.L. Mechanisms of cholesterol and sterol regulatory element binding protein regulation of the sterol 12α- hydroxylase gene (CYP8B1). Biochem. Biophys. Res. Commun., 2004, 320(4), 1204-1210.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.320
, Issue.4
, pp. 1204-1210
-
-
Yang, Y.1
Eggertsen, G.2
Gåfvels, M.3
Andersson, U.4
Einarsson, C.5
Björkhem, I.6
Chiang, J.Y.L.7
-
401
-
-
0034597670
-
Down-regulation of murine Cyp1a-1 in mouse hepatoma Hepa-1c1c7 cells by bisphenol A
-
Jeong, H.G.; Kimand, J.Y.; Choi, C.Y. Down-regulation of murine Cyp1a-1 in mouse hepatoma Hepa-1c1c7 cells by bisphenol A. Biochem. Biophys. Res. Commun., 2000, 277(3), 594-598.
-
(2000)
Biochem. Biophys. Res. Commun
, vol.277
, Issue.3
, pp. 594-598
-
-
Jeong, H.G.1
Kimand, J.Y.2
Choi, C.Y.3
-
402
-
-
13244258414
-
The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice
-
Teng, S.; Piquette-Miller, M. The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice. J. Pharmacol. Exp. Ther., 2005, 312(2), 841-848.
-
(2005)
J. Pharmacol. Exp. Ther
, vol.312
, Issue.2
, pp. 841-848
-
-
Teng, S.1
Piquette-Miller, M.2
-
403
-
-
0031871085
-
Down-regulation of cytochrome P450 mRNAs and proteins in mice lacking a functional NOS2 gene
-
Sewer, M.B.; Barclay, T.B.; Morgan, E.T. Down-regulation of cytochrome P450 mRNAs and proteins in mice lacking a functional NOS2 gene. Mol. Pharmacol., 1998, 54(2), 273-279.
-
(1998)
Mol. Pharmacol
, vol.54
, Issue.2
, pp. 273-279
-
-
Sewer, M.B.1
Barclay, T.B.2
Morgan, E.T.3
-
404
-
-
0036367792
-
Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response
-
Wei, P.; Zhang, J.; Dowhan, D.H.; Han, Y.; Moore, D.D. Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response. Pharmacogenom. J., 2002, 2(2), 117-126.
-
(2002)
Pharmacogenom. J
, vol.2
, Issue.2
, pp. 117-126
-
-
Wei, P.1
Zhang, J.2
Dowhan, D.H.3
Han, Y.4
Moore, D.D.5
-
405
-
-
0008014571
-
Role of extrahepatic metabolism in drug disposition and toxicity
-
Testa, B, Jenner, P, Eds, Marcel Dekker, Inc, New York
-
Vainio, H.; Hietanen, E. Role of extrahepatic metabolism in drug disposition and toxicity. In Concepts in Drug Metabolism; Testa, B., Jenner, P., Eds.; Marcel Dekker, Inc.: New York, 1980, pp. 251-284.
-
(1980)
Concepts in Drug Metabolism
, pp. 251-284
-
-
Vainio, H.1
Hietanen, E.2
-
406
-
-
23044436687
-
CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice
-
Wagner, M.; Halilbasic, E.; Marschall, H.U.; Zollner, G.; Fickert, P.; Langner, C.; Zatloukal, K.; Denk, H.; Trauner, M. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice. Hepatology, 2005, 42(2), 420-430.
-
(2005)
Hepatology
, vol.42
, Issue.2
, pp. 420-430
-
-
Wagner, M.1
Halilbasic, E.2
Marschall, H.U.3
Zollner, G.4
Fickert, P.5
Langner, C.6
Zatloukal, K.7
Denk, H.8
Trauner, M.9
-
407
-
-
0036236065
-
Induction of CYP3A expression by dehydroepiandrosterone: Involvement of the pregnane X receptor
-
Ripp, S.L.; Fitzpatrick, J.L.; Peters, J.M.; Prough, R.A. Induction of CYP3A expression by dehydroepiandrosterone: involvement of the pregnane X receptor. Drug Metab. Dispos., 2002, 30(5), 570-575.
-
(2002)
Drug Metab. Dispos
, vol.30
, Issue.5
, pp. 570-575
-
-
Ripp, S.L.1
Fitzpatrick, J.L.2
Peters, J.M.3
Prough, R.A.4
-
408
-
-
0344519717
-
Induction of cytochrome P450 3A by paclitaxel in mice: Pivotal role of the nuclear xenobiotic receptor, pregnane X receptor
-
Nallani, S.C.; Goodwin, B.; Maglich, J.M.; Buckley, D.J.; Buckley, A.R.; Desai, P.B. Induction of cytochrome P450 3A by paclitaxel in mice: pivotal role of the nuclear xenobiotic receptor, pregnane X receptor. Drug Metab. Dispos., 2003, 31(5), 681-684.
-
(2003)
Drug Metab. Dispos
, vol.31
, Issue.5
, pp. 681-684
-
-
Nallani, S.C.1
Goodwin, B.2
Maglich, J.M.3
Buckley, D.J.4
Buckley, A.R.5
Desai, P.B.6
-
409
-
-
34249747403
-
Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis
-
Teng, S.; Piquette-Miller, M. Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis. Br. J. Pharmacol., 2007, 151(3), 367-376.
-
(2007)
Br. J. Pharmacol
, vol.151
, Issue.3
, pp. 367-376
-
-
Teng, S.1
Piquette-Miller, M.2
-
410
-
-
3342977959
-
Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor
-
Brobst, D.E.; Ding, X.; Creech, K.L.; Goodwin, B.; Kelley, B.; Staudinger, J.L. Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor. J. Pharmacol. Exp. Ther., 2004, 310(2), 528-535.
-
(2004)
J. Pharmacol. Exp. Ther
, vol.310
, Issue.2
, pp. 528-535
-
-
Brobst, D.E.1
Ding, X.2
Creech, K.L.3
Goodwin, B.4
Kelley, B.5
Staudinger, J.L.6
-
411
-
-
35548992006
-
Disruption of clock gene expression alters responses of the aryl hydrocarbon receptor signaling pathway in the mouse mammary gland
-
Qu, X.; Metz, R.P.; Porter, W.W.; Cassone, V.M.; Earnest, D.J. Disruption of clock gene expression alters responses of the aryl hydrocarbon receptor signaling pathway in the mouse mammary gland. Mol. Pharmacol., 2007, 72(5), 1349-1358.
-
(2007)
Mol. Pharmacol
, vol.72
, Issue.5
, pp. 1349-1358
-
-
Qu, X.1
Metz, R.P.2
Porter, W.W.3
Cassone, V.M.4
Earnest, D.J.5
-
412
-
-
55349131019
-
Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o,p'-DDT
-
Kiyosawa, N.; Kwekel, J.C.; Burgoon, L.D.; Dere, E.; Williams, K.J.; Tashiro, C.; Chittim, B.; Zacharewski, T.R. Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o,p'-DDT. BMC Genomics, 2008, 9(1), 487-499.
-
(2008)
BMC Genomics
, vol.9
, Issue.1
, pp. 487-499
-
-
Kiyosawa, N.1
Kwekel, J.C.2
Burgoon, L.D.3
Dere, E.4
Williams, K.J.5
Tashiro, C.6
Chittim, B.7
Zacharewski, T.R.8
-
413
-
-
33747070775
-
In vivo and mechanistic evidence of nuclear receptor CAR induction by artemisinin
-
Simonsson, U.S.H.; Lindell, M.; Raffalli-Mathieu, F.; Lannerbro, A.; Honkakoski, P.; Lang, M.A. In vivo and mechanistic evidence of nuclear receptor CAR induction by artemisinin. Eur. J. Clin. Investig., 2006, 36(9), 647-653.
-
(2006)
Eur. J. Clin. Investig
, vol.36
, Issue.9
, pp. 647-653
-
-
Simonsson, U.S.H.1
Lindell, M.2
Raffalli-Mathieu, F.3
Lannerbro, A.4
Honkakoski, P.5
Lang, M.A.6
-
414
-
-
33845794361
-
Regulation and induction of CYP3A11, CYP3A13 and CYP3A25 in C57BL/6J mouse liver
-
Down, M.J.; Arkle, S.; Mills, J.J. Regulation and induction of CYP3A11, CYP3A13 and CYP3A25 in C57BL/6J mouse liver. Arch. Biochem. Biophys., 2007, 457(1), 105-110.
-
(2007)
Arch. Biochem. Biophys
, vol.457
, Issue.1
, pp. 105-110
-
-
Down, M.J.1
Arkle, S.2
Mills, J.J.3
-
415
-
-
34347263448
-
The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators
-
Pacyniak, E.K.; Cheng, X.; Cunningham, M.L.; Crofton, K.; Klaassen, C.D.; Guo, G.L. The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators. Toxicol. Sci., 2007, 97(1), 94-102.
-
(2007)
Toxicol. Sci
, vol.97
, Issue.1
, pp. 94-102
-
-
Pacyniak, E.K.1
Cheng, X.2
Cunningham, M.L.3
Crofton, K.4
Klaassen, C.D.5
Guo, G.L.6
-
416
-
-
34347270605
-
The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors
-
Ricketts, M.L.. Boekschoten, M.V.; Kreeft, A.J.; Hooiveld, G.J.E.J.; Moen, C.J.A.; Müller, M.; Frants, R.R.; Kasanmoentalib, S.; Post, S.M.; Princen, H.M.G.; Porter, J.G.; Katan, M.B.; Hofker, M.H.; Moore, D.D. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol. Endocrinol., 2007, 21(7), 1603-1616.
-
(2007)
Mol. Endocrinol
, vol.21
, Issue.7
, pp. 1603-1616
-
-
Ricketts, M.L.1
Boekschoten, M.V.2
Kreeft, A.J.3
Hooiveld, G.J.E.J.4
Moen, C.J.A.5
Müller, M.6
Frants, R.R.7
Kasanmoentalib, S.8
Post, S.M.9
Princen, H.M.G.10
Porter, J.G.11
Katan, M.B.12
Hofker, M.H.13
Moore, D.D.14
-
417
-
-
51349112400
-
A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response
-
Scheer, N.; Ross, J.; Rode, A.; Zevnik, B.; Niehaves, S.; Faust, N.; Wolf, C.R. A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response. J. Clin. Invest., 2008, 118(9), 3228-3239.
-
(2008)
J. Clin. Invest
, vol.118
, Issue.9
, pp. 3228-3239
-
-
Scheer, N.1
Ross, J.2
Rode, A.3
Zevnik, B.4
Niehaves, S.5
Faust, N.6
Wolf, C.R.7
-
418
-
-
0033591297
-
Identification of a nuclear receptor for bile acids
-
Makishima, M.; Okamoto, A.Y.; Repa, J.J.; Tu, H.; Learned, R.M.; Luk, A.; Hull, M.V.; Lustig, K.D.; Mangelsdorf, D.J.; Shan, B. Identification of a nuclear receptor for bile acids. Science, 1999, 284(5418), 1362-1365.
-
(1999)
Science
, vol.284
, Issue.5418
, pp. 1362-1365
-
-
Makishima, M.1
Okamoto, A.Y.2
Repa, J.J.3
Tu, H.4
Learned, R.M.5
Luk, A.6
Hull, M.V.7
Lustig, K.D.8
Mangelsdorf, D.J.9
Shan, B.10
-
419
-
-
33744482554
-
Reproductive and endocrine effects of pnonylphenol and methoxychlor: A review
-
Bandiera, S.M. Reproductive and endocrine effects of pnonylphenol and methoxychlor: a review. Immun. Endocr. Metab. Agents in Med. Chem., 2006, 6(1), 15-26.
-
(2006)
Immun. Endocr. Metab. Agents in Med. Chem
, vol.6
, Issue.1
, pp. 15-26
-
-
Bandiera, S.M.1
-
420
-
-
23944516070
-
Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4α
-
Ferguson, S.S.; Chen, Y.; LeCluyse, E.L.; Negishi, M.; Goldstein, J.A. Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4α. Mol. Pharmacol., 2005, 68(3), 747-757.
-
(2005)
Mol. Pharmacol
, vol.68
, Issue.3
, pp. 747-757
-
-
Ferguson, S.S.1
Chen, Y.2
LeCluyse, E.L.3
Negishi, M.4
Goldstein, J.A.5
-
421
-
-
0031968936
-
Activation by diverse xenochemicals of the 51-base pair phenobarbitalresponsive enhancer module in the CYP2B10 gene
-
Honkakoski, P.; Moore, R.; Washburn, K.A.; Negishi, M. Activation by diverse xenochemicals of the 51-base pair phenobarbitalresponsive enhancer module in the CYP2B10 gene. Mol. Pharmacol., 1998, 53(4), 597-601.
-
(1998)
Mol. Pharmacol
, vol.53
, Issue.4
, pp. 597-601
-
-
Honkakoski, P.1
Moore, R.2
Washburn, K.A.3
Negishi, M.4
-
422
-
-
33751541421
-
Phenytoin induction of the Cyp2c37 gene is mediated by the constitutive androstane receptor
-
Jackson, J.P.; Ferguson, S.S.; Negishi, M.; Goldstein, J.A. Phenytoin induction of the Cyp2c37 gene is mediated by the constitutive androstane receptor. Drug Metab. Dispos., 2006, 34(12), 2003-2010.
-
(2006)
Drug Metab. Dispos
, vol.34
, Issue.12
, pp. 2003-2010
-
-
Jackson, J.P.1
Ferguson, S.S.2
Negishi, M.3
Goldstein, J.A.4
-
423
-
-
0038798874
-
Drug-activated nuclear receptors CAR and PXR
-
Honkakoski, P.; Sueyoshi, T.; Negishi, M. Drug-activated nuclear receptors CAR and PXR. Ann. Med., 2003, 35(3), 172-182.
-
(2003)
Ann. Med
, vol.35
, Issue.3
, pp. 172-182
-
-
Honkakoski, P.1
Sueyoshi, T.2
Negishi, M.3
-
424
-
-
8444233675
-
Induction of hepatic Cyp2b and Cyp3a subfamily enzymes by nicardipine and nifedipine in mice
-
Konno, Y.; Sekimoto, M.; Nemoto, K.; Degawa, M. Induction of hepatic Cyp2b and Cyp3a subfamily enzymes by nicardipine and nifedipine in mice. Xenobiotica, 2004, 34(7), 607-618.
-
(2004)
Xenobiotica
, vol.34
, Issue.7
, pp. 607-618
-
-
Konno, Y.1
Sekimoto, M.2
Nemoto, K.3
Degawa, M.4
-
425
-
-
13844255025
-
α-Tocopherol modulates Cyp3a expression, increases γ-CEHC production, and limits tissue γ-tocopherol accumulation in mice fed high γ-tocopherol diets
-
Traber, M.G.; Siddens, L.K.; Leonard, S.W.; Schock, B.; Gohil, K.; Krueger, S.K.; Cross, C.E.; Williams, D.E. α-Tocopherol modulates Cyp3a expression, increases γ-CEHC production, and limits tissue γ-tocopherol accumulation in mice fed high γ-tocopherol diets. Free Radic. Biol. Med., 2005, 38(6), 773-785.
-
(2005)
Free Radic. Biol. Med
, vol.38
, Issue.6
, pp. 773-785
-
-
Traber, M.G.1
Siddens, L.K.2
Leonard, S.W.3
Schock, B.4
Gohil, K.5
Krueger, S.K.6
Cross, C.E.7
Williams, D.E.8
-
426
-
-
34748821996
-
Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport
-
Petrick, J.S.; Klaassen, C.D. Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport. Drug Metab. Dispos., 2007, 35(10), 1806-1815.
-
(2007)
Drug Metab. Dispos
, vol.35
, Issue.10
, pp. 1806-1815
-
-
Petrick, J.S.1
Klaassen, C.D.2
-
427
-
-
0033652116
-
Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene
-
Kawamoto, T.; Kakizaki, S.; Yoshinari, K.; Negishi, M. Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene. Mol. Endocrinol., 2000, 14(11), 1897-1905.
-
(2000)
Mol. Endocrinol
, vol.14
, Issue.11
, pp. 1897-1905
-
-
Kawamoto, T.1
Kakizaki, S.2
Yoshinari, K.3
Negishi, M.4
-
428
-
-
0037931737
-
Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes
-
Maglich, J.M.; Parks, D.J.; Moore, L.B.; Collins, J.L.; Goodwin, B.; Billin, A.N.; Stoltz, C.A.; Kliewer, S.A.; Lambert, M.H.; Willson, T.M.; Moore, J.T. Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes. J. Biol. Chem., 2003, 278(19), 17277-17283.
-
(2003)
J. Biol. Chem
, vol.278
, Issue.19
, pp. 17277-17283
-
-
Maglich, J.M.1
Parks, D.J.2
Moore, L.B.3
Collins, J.L.4
Goodwin, B.5
Billin, A.N.6
Stoltz, C.A.7
Kliewer, S.A.8
Lambert, M.H.9
Willson, T.M.10
Moore, J.T.11
-
429
-
-
33751170721
-
Induction of human CYP2A6 is mediated by the pregnane X receptor with peroxisome proliferator-activated receptor-γ coactivator 1α
-
Itoh, M.; Nakajima, M.; Higashi, E.; Yoshida, R.; Nagata, K.; Yamazoe, Y.; Yokoi, T. Induction of human CYP2A6 is mediated by the pregnane X receptor with peroxisome proliferator-activated receptor-γ coactivator 1α. J. Pharmacol. Exp. Ther., 2006, 319(2), 693-702.
-
(2006)
J. Pharmacol. Exp. Ther
, vol.319
, Issue.2
, pp. 693-702
-
-
Itoh, M.1
Nakajima, M.2
Higashi, E.3
Yoshida, R.4
Nagata, K.5
Yamazoe, Y.6
Yokoi, T.7
-
430
-
-
0034012654
-
The glucocorticoid receptor is essential for induction of cytochrome P-4502B by steroids but not for drug or steroid induction of CYP3A or P-450 reductase in mouse liver
-
Schuetz, E.G.; Schmid, W.; Schutz, G.; Brimer, C.; Yasuda, K.; Kamataki, T.; Bornheim, L.; Myles, K.; Cole, T.J. The glucocorticoid receptor is essential for induction of cytochrome P-4502B by steroids but not for drug or steroid induction of CYP3A or P-450 reductase in mouse liver. Drug Metab. Dispos., 2000, 28(3), 268-278.
-
(2000)
Drug Metab. Dispos
, vol.28
, Issue.3
, pp. 268-278
-
-
Schuetz, E.G.1
Schmid, W.2
Schutz, G.3
Brimer, C.4
Yasuda, K.5
Kamataki, T.6
Bornheim, L.7
Myles, K.8
Cole, T.J.9
-
431
-
-
61449167104
-
Dexamethasone induction of murine CYP2B genes requires the glucocorticoid receptor
-
Audet-Walsh, É.; Anderson, A. Dexamethasone induction of murine CYP2B genes requires the glucocorticoid receptor. Drug Metab. Dispos., 2009, 37(3), 580-588.
-
(2009)
Drug Metab. Dispos
, vol.37
, Issue.3
, pp. 580-588
-
-
Audet-Walsh, E.1
Anderson, A.2
-
432
-
-
33845924452
-
Gender dictates the nuclear receptor-mediated regulation of CYP3A44
-
Anakk, S.; Huang, W.; Staudinger, J.L.; Tan, K.; Cole, T.J.; Moore, D.D.; Strobel, H.W. Gender dictates the nuclear receptor-mediated regulation of CYP3A44. Drug Metab. Dispos., 2007, 35(1), 36-42.
-
(2007)
Drug Metab. Dispos
, vol.35
, Issue.1
, pp. 36-42
-
-
Anakk, S.1
Huang, W.2
Staudinger, J.L.3
Tan, K.4
Cole, T.J.5
Moore, D.D.6
Strobel, H.W.7
-
433
-
-
34748824383
-
Involvement of glucocorticoid receptor and pregnane X receptor in the regulation of mouse CYP3A44 femalepredominant expression by glucocorticoid hormone
-
Bhadhprasit, W.; Sakuma, T.; Hatakeyama, N.; Fuwa, M.; Kitajima, K.; Nemoto, N. Involvement of glucocorticoid receptor and pregnane X receptor in the regulation of mouse CYP3A44 femalepredominant expression by glucocorticoid hormone. Drug Metab. Dispos., 2007, 35(10), 1880-1885.
-
(2007)
Drug Metab. Dispos
, vol.35
, Issue.10
, pp. 1880-1885
-
-
Bhadhprasit, W.1
Sakuma, T.2
Hatakeyama, N.3
Fuwa, M.4
Kitajima, K.5
Nemoto, N.6
-
434
-
-
0348038715
-
Transcriptional regulation of cytochrome P450 2B genes by nuclear receptors
-
Wang, H.; Negishi, M. Transcriptional regulation of cytochrome P450 2B genes by nuclear receptors. Curr. Drug Metab., 2003, 4(6), 515-525.
-
(2003)
Curr. Drug Metab
, vol.4
, Issue.6
, pp. 515-525
-
-
Wang, H.1
Negishi, M.2
-
435
-
-
23944483961
-
CAR and PXR: Xenosensors of endocrine disruptors
-
Kretschmer, X.C.; Baldwin, W.S. CAR and PXR: xenosensors of endocrine disruptors. Chem.-Biol. Interact., 2005, 155(3), 111-128.
-
(2005)
Chem.-Biol. Interact
, vol.155
, Issue.3
, pp. 111-128
-
-
Kretschmer, X.C.1
Baldwin, W.S.2
-
436
-
-
33646693667
-
Synthetic drugs and natural products as modulators of constitutive androstane receptor (CAR) and pregnane X receptor (PXR)
-
Chang, T.K.H.; Waxman, D.J. Synthetic drugs and natural products as modulators of constitutive androstane receptor (CAR) and pregnane X receptor (PXR). Drug Metab. Rev., 2006, 38(1-2), 51-73.
-
(2006)
Drug Metab. Rev
, vol.38
, Issue.1-2
, pp. 51-73
-
-
Chang, T.K.H.1
Waxman, D.J.2
-
437
-
-
0344740559
-
Induction of drug metabolism: The role of nuclear receptors
-
Handschin, C.; Meyer, U.A. Induction of drug metabolism: the role of nuclear receptors. Pharmacol. Rev., 2003, 55(4), 649-673.
-
(2003)
Pharmacol. Rev
, vol.55
, Issue.4
, pp. 649-673
-
-
Handschin, C.1
Meyer, U.A.2
-
438
-
-
33847024555
-
CAR and PXR: The xenobiotic-sensing receptors
-
Timsit, Y.E.; Negishi, M. CAR and PXR: the xenobiotic-sensing receptors. Steroids, 2007, 72(3), 231-246.
-
(2007)
Steroids
, vol.72
, Issue.3
, pp. 231-246
-
-
Timsit, Y.E.1
Negishi, M.2
-
439
-
-
0030908295
-
Characterization of a phenobarbitalresponsive enhancer module in mouse P450 Cyp2b10 gene
-
Honkakoski, P.; Negishi, M. Characterization of a phenobarbitalresponsive enhancer module in mouse P450 Cyp2b10 gene. J. Biol. Chem., 1997, 272(23), 14943-14949.
-
(1997)
J. Biol. Chem
, vol.272
, Issue.23
, pp. 14943-14949
-
-
Honkakoski, P.1
Negishi, M.2
-
440
-
-
0036077019
-
Effect of hyperinsulinemia and type 2 diabetes-like hyperglycemia on expression of hepatic cytochrome P450 and glutathione S-transferase isoforms in a New Zealand obese-derived mouse backcross population
-
Pass, G.J.; Becker, W.; Kluge, R.; Linnartz, K.; Plum, L.; Giesen, K.; Joost, H.G. Effect of hyperinsulinemia and type 2 diabetes-like hyperglycemia on expression of hepatic cytochrome P450 and glutathione S-transferase isoforms in a New Zealand obese-derived mouse backcross population. J. Pharmacol. Exp. Ther., 2002, 302(2), 442-450.
-
(2002)
J. Pharmacol. Exp. Ther
, vol.302
, Issue.2
, pp. 442-450
-
-
Pass, G.J.1
Becker, W.2
Kluge, R.3
Linnartz, K.4
Plum, L.5
Giesen, K.6
Joost, H.G.7
-
441
-
-
33646513294
-
Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds
-
Reschly, E.J.; Krasowski, M.D. Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds. Curr. Drug Metab., 2006, 7(4), 349-365.
-
(2006)
Curr. Drug Metab
, vol.7
, Issue.4
, pp. 349-365
-
-
Reschly, E.J.1
Krasowski, M.D.2
-
442
-
-
8444252573
-
Cross-talk between xenobiotic detoxication and other signalling pathways: Clinical and toxicological consequences
-
Pascussi, J.M.; Gerbal-Chaloin, S.; Drocourt, L.; Assénat, E.; Larrey, D.; Pichard-Garcia, L.; Vilarem, M.J.; Maurel, P. Cross-talk between xenobiotic detoxication and other signalling pathways: clinical and toxicological consequences. Xenobiotica, 2004, 34(7), 633-664.
-
(2004)
Xenobiotica
, vol.34
, Issue.7
, pp. 633-664
-
-
Pascussi, J.M.1
Gerbal-Chaloin, S.2
Drocourt, L.3
Assénat, E.4
Larrey, D.5
Pichard-Garcia, L.6
Vilarem, M.J.7
Maurel, P.8
-
443
-
-
0032169485
-
The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
-
Lehmann, J.M.; McKee, D.D.; Watson, M.A.; Willson, T.M.; Moore, J.T.; Kliewer, S.A. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J. Clin. Invest., 1998, 102(5), 1016-1023.
-
(1998)
J. Clin. Invest
, vol.102
, Issue.5
, pp. 1016-1023
-
-
Lehmann, J.M.1
McKee, D.D.2
Watson, M.A.3
Willson, T.M.4
Moore, J.T.5
Kliewer, S.A.6
-
444
-
-
13244291443
-
Induction of drug metabolism by forskolin: The role of the pregnane X receptor and the protein kinase A signal transduction pathway
-
Ding, X.; Staudinger, J.L. Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase A signal transduction pathway. J. Pharmacol. Exp. Ther., 2005, 312(2), 849-856.
-
(2005)
J. Pharmacol. Exp. Ther
, vol.312
, Issue.2
, pp. 849-856
-
-
Ding, X.1
Staudinger, J.L.2
-
445
-
-
43049128132
-
Retinoids induce cytochrome P450 3A4 through RXR/VDR-mediated pathway
-
Wang, K.; Chen, S.; Xie, W.; Wan, Y.J.Y. Retinoids induce cytochrome P450 3A4 through RXR/VDR-mediated pathway. Biochem. Pharmacol., 2008, 75(11), 2204-2213.
-
(2008)
Biochem. Pharmacol
, vol.75
, Issue.11
, pp. 2204-2213
-
-
Wang, K.1
Chen, S.2
Xie, W.3
Wan, Y.J.Y.4
-
446
-
-
47949083957
-
The traditional Chinese herbal remedy tian xian activates pregnane X receptor and induces CYP3A gene expression in hepatocytes
-
Lichti-Kaiser, K.; Staudinger, J.L. The traditional Chinese herbal remedy tian xian activates pregnane X receptor and induces CYP3A gene expression in hepatocytes. Drug Metab. Dispos., 2008, 36(8), 1538-1545.
-
(2008)
Drug Metab. Dispos
, vol.36
, Issue.8
, pp. 1538-1545
-
-
Lichti-Kaiser, K.1
Staudinger, J.L.2
-
447
-
-
67349105004
-
Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: A key role for the pregnane X receptor
-
Harmsen, S.; Meijerman, I.; Beijnen, J.H.; Schellens, J.H.M. Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor. Cancer Chemother. Pharmacol., 2009, 64(1), 35-43.
-
(2009)
Cancer Chemother. Pharmacol
, vol.64
, Issue.1
, pp. 35-43
-
-
Harmsen, S.1
Meijerman, I.2
Beijnen, J.H.3
Schellens, J.H.M.4
-
448
-
-
8844228096
-
A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides
-
Lemaire, G.; de Sousa, G.; Rahmani, R. A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides. Biochem. Pharmacol., 2004, 68(12), 2347-2358.
-
(2004)
Biochem. Pharmacol
, vol.68
, Issue.12
, pp. 2347-2358
-
-
Lemaire, G.1
de Sousa, G.2
Rahmani, R.3
-
449
-
-
33750296572
-
Nicotine induces brain CYP enzymes: Relevance to Parkinson's disease
-
Miksys, S.; Tyndale, R.F. Nicotine induces brain CYP enzymes: relevance to Parkinson's disease. J. Neural Transm., 2006, 70(Suppl.), 177-180.
-
(2006)
J. Neural Transm
, vol.70
, Issue.SUPPL.
, pp. 177-180
-
-
Miksys, S.1
Tyndale, R.F.2
-
450
-
-
0037501542
-
2.1 Å crystal structure of human PXR in complex with the St. John's wort compound hyperforin
-
Watkins, R.E.; Maglich, J.M.; Moore, L.B.; Wisely, G.B.; Noble, S.M.; Davis-Searles, P.R.; Lambert, M.H.; Kliewer, S.A.; Redinbo, M.R. 2.1 Å crystal structure of human PXR in complex with the St. John's wort compound hyperforin. Biochemistry, 2003, 42(6), 1430-1438.
-
(2003)
Biochemistry
, vol.42
, Issue.6
, pp. 1430-1438
-
-
Watkins, R.E.1
Maglich, J.M.2
Moore, L.B.3
Wisely, G.B.4
Noble, S.M.5
Davis-Searles, P.R.6
Lambert, M.H.7
Kliewer, S.A.8
Redinbo, M.R.9
-
451
-
-
17844396881
-
Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin
-
Chrencik, J.E.; Orans, J.; Moore, L.B.; Xue, Y.; Peng, L.; Collins, J.L.; Wisely, G.B.; Lambert, M.H.; Kliewer, S.A.; Redinbo, M.R. Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin. Mol. Endocrinol., 2005, 19(5), 1125-1134.
-
(2005)
Mol. Endocrinol
, vol.19
, Issue.5
, pp. 1125-1134
-
-
Chrencik, J.E.1
Orans, J.2
Moore, L.B.3
Xue, Y.4
Peng, L.5
Collins, J.L.6
Wisely, G.B.7
Lambert, M.H.8
Kliewer, S.A.9
Redinbo, M.R.10
-
452
-
-
0347689682
-
Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers
-
Faucette, S.R.; Wang, H.; Hamilton, G.A.; Jolley, S.L.; Gilbert, D.; Lindley, C.; Yan, B.; Negishi, M.; LeCluyse, E.L. Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers. Drug Metab. Dispos., 2004, 32(3), 348-358.
-
(2004)
Drug Metab. Dispos
, vol.32
, Issue.3
, pp. 348-358
-
-
Faucette, S.R.1
Wang, H.2
Hamilton, G.A.3
Jolley, S.L.4
Gilbert, D.5
Lindley, C.6
Yan, B.7
Negishi, M.8
LeCluyse, E.L.9
-
453
-
-
22344439421
-
Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor
-
Kobayashi, K.; Yamanaka, Y.; Iwazaki, N.; Nakajo, I.; Hosokawa, M.; Negishi, M.; Chiba, K. Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor. Drug Metab. Dispos., 2005, 33(7), 924-929.
-
(2005)
Drug Metab. Dispos
, vol.33
, Issue.7
, pp. 924-929
-
-
Kobayashi, K.1
Yamanaka, Y.2
Iwazaki, N.3
Nakajo, I.4
Hosokawa, M.5
Negishi, M.6
Chiba, K.7
-
454
-
-
0037437790
-
Vitamin E activates gene expression via the pregnane X receptor
-
Landes, N.; Pfluger, P.; Kluth, D.; Birringer, M.; Rühl, R.; Böl, G.F.; Glatt, H.; Brigelius-Flohé, R. Vitamin E activates gene expression via the pregnane X receptor. Biochem. Pharmacol., 2003, 65(2), 269-273.
-
(2003)
Biochem. Pharmacol
, vol.65
, Issue.2
, pp. 269-273
-
-
Landes, N.1
Pfluger, P.2
Kluth, D.3
Birringer, M.4
Rühl, R.5
Böl, G.F.6
Glatt, H.7
Brigelius-Flohé, R.8
-
455
-
-
0035914467
-
Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450
-
Schuetz, E.G.; Strom, S.; Yasuda, K.; Lecureur, V.; Assem, M.; Brimer, C.; Lamba, J.; Kim, R.B.; Ramachandran, V.; Komoroski, B.J.; Venkataramanan, R.; Cai, H.; Sinal, C.J.; Gonzalez, F.J.; Schuetz, J.D. Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450. J. Biol. Chem., 2001, 276(42), 39411-39418.
-
(2001)
J. Biol. Chem
, vol.276
, Issue.42
, pp. 39411-39418
-
-
Schuetz, E.G.1
Strom, S.2
Yasuda, K.3
Lecureur, V.4
Assem, M.5
Brimer, C.6
Lamba, J.7
Kim, R.B.8
Ramachandran, V.9
Komoroski, B.J.10
Venkataramanan, R.11
Cai, H.12
Sinal, C.J.13
Gonzalez, F.J.14
Schuetz, J.D.15
-
456
-
-
2942719062
-
Regulation of CYP2E1 by ethanol and palmitic acid and CYP4A11 by clofibrate in primary cultures of human hepatocytes
-
Raucy, J.L.; Lasker, J.; Ozaki, K.; Zoleta, V. Regulation of CYP2E1 by ethanol and palmitic acid and CYP4A11 by clofibrate in primary cultures of human hepatocytes. Toxicol. Sci., 2004, 79(2), 233-241.
-
(2004)
Toxicol. Sci
, vol.79
, Issue.2
, pp. 233-241
-
-
Raucy, J.L.1
Lasker, J.2
Ozaki, K.3
Zoleta, V.4
-
457
-
-
0037417994
-
Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance
-
Dussault, I.; Yoo, H.D.; Lin, M.; Wang, E.; Fan, M.; Batta, A.K.; Salen, G.; Erickson, S.K.; Forman, B.M. Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance. Proc. Natl. Acad. Sci. USA, 2003, 100(3), 833-838.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.3
, pp. 833-838
-
-
Dussault, I.1
Yoo, H.D.2
Lin, M.3
Wang, E.4
Fan, M.5
Batta, A.K.6
Salen, G.7
Erickson, S.K.8
Forman, B.M.9
-
458
-
-
0041881764
-
Hyperforin contributes to the hepatic CYP3A-inducing effect of Hypericum perforatum extract in the mouse
-
Cantoni, L.; Rozio, M.; Mangolini, A.; Hauri, L.; Caccia, S. Hyperforin contributes to the hepatic CYP3A-inducing effect of Hypericum perforatum extract in the mouse. Toxicol. Sci., 2003, 75(1), 25-30.
-
(2003)
Toxicol. Sci
, vol.75
, Issue.1
, pp. 25-30
-
-
Cantoni, L.1
Rozio, M.2
Mangolini, A.3
Hauri, L.4
Caccia, S.5
-
459
-
-
4143153180
-
Effect of prototypical inducing agents on P-glycoprotein and CYP3A expression in mouse tissues
-
Matheny, C.J.; Ali, R.Y.; Yang, X.; Pollack, G.M. Effect of prototypical inducing agents on P-glycoprotein and CYP3A expression in mouse tissues. Drug Metab. Dispos., 2004, 32(9), 1008-1014.
-
(2004)
Drug Metab. Dispos
, vol.32
, Issue.9
, pp. 1008-1014
-
-
Matheny, C.J.1
Ali, R.Y.2
Yang, X.3
Pollack, G.M.4
-
460
-
-
4444223732
-
Cytochrome P450 enzymes: Novel options for cancer therapeutics
-
McFadyen, M.C.E.; Melvin, W.T.; Murray, G.I. Cytochrome P450 enzymes: novel options for cancer therapeutics. Mol. Cancer Ther., 2004, 3(3), 363-371.
-
(2004)
Mol. Cancer Ther
, vol.3
, Issue.3
, pp. 363-371
-
-
McFadyen, M.C.E.1
Melvin, W.T.2
Murray, G.I.3
-
461
-
-
35349013674
-
Role of nitric oxide in downregulation of cytochrome P450 1a1 and NADPH: Quinine oxidoreductase 1 by tumor necrosis factor-α and lipopolysaccharide
-
Gharavi, N.; El-Kadi, A.O.S. Role of nitric oxide in downregulation of cytochrome P450 1a1 and NADPH: quinine oxidoreductase 1 by tumor necrosis factor-α and lipopolysaccharide. J. Pharm. Sci., 2007, 96(10), 2795-2807.
-
(2007)
J. Pharm. Sci
, vol.96
, Issue.10
, pp. 2795-2807
-
-
Gharavi, N.1
El-Kadi, A.O.S.2
-
462
-
-
0035836782
-
Suppression of CYP1A1 expression by 4-nonylphenol in murine Hepa-1c1c7 cells
-
Jeong, H.G.; Kim, J.Y.; Choi, C.Y.; You, H.J.; Hahm, K. Suppression of CYP1A1 expression by 4-nonylphenol in murine Hepa-1c1c7 cells. Cancer Lett., 2001, 165(1), 95-101.
-
(2001)
Cancer Lett
, vol.165
, Issue.1
, pp. 95-101
-
-
Jeong, H.G.1
Kim, J.Y.2
Choi, C.Y.3
You, H.J.4
Hahm, K.5
-
463
-
-
52949152347
-
Identification of human hepatic cytochrome P450 enzymes involved in the biotransformation of cholic and chenodeoxycholic acid
-
Deo, A.K.; Bandiera, S.M. Identification of human hepatic cytochrome P450 enzymes involved in the biotransformation of cholic and chenodeoxycholic acid. Drug Metab. Dispos., 2008, 36(10), 1983-1991.
-
(2008)
Drug Metab. Dispos
, vol.36
, Issue.10
, pp. 1983-1991
-
-
Deo, A.K.1
Bandiera, S.M.2
-
464
-
-
70349085443
-
3-Ketocholanoic acid is the major in vitro human hepatic microsomal metabolite of lithocholic acid
-
Deo, A.K.; Bandiera, S.M. 3-Ketocholanoic acid is the major in vitro human hepatic microsomal metabolite of lithocholic acid. Drug Metab. Dispos., 2009, 37(9), 1938-1947.
-
(2009)
Drug Metab. Dispos
, vol.37
, Issue.9
, pp. 1938-1947
-
-
Deo, A.K.1
Bandiera, S.M.2
-
465
-
-
68149134517
-
Modulation of androgen and estrogen receptor expression by antiepileptic drugs and steroids in hippocampus of patients with temporary lobe epilepsy
-
Killer, N.; Hock, M.; Gehlhaus, M.; Capetian, P.; Knoth, R.; Pantazis, G.; Volk, B.; Meyer, R.P. Modulation of androgen and estrogen receptor expression by antiepileptic drugs and steroids in hippocampus of patients with temporary lobe epilepsy. Epilepsy, 2009, 50(8), 1875-1890.
-
(2009)
Epilepsy
, vol.50
, Issue.8
, pp. 1875-1890
-
-
Killer, N.1
Hock, M.2
Gehlhaus, M.3
Capetian, P.4
Knoth, R.5
Pantazis, G.6
Volk, B.7
Meyer, R.P.8
-
466
-
-
1642483471
-
Feed-forward regulation of bile acid detoxification by CYP3A4: Studies in humanized transgenic mice
-
Stedman, C.; Robertson, G.; Coulter, S.; Liddle, C. Feed-forward regulation of bile acid detoxification by CYP3A4: studies in humanized transgenic mice. J. Biol. Chem., 2004, 279(12), 11336-11343.
-
(2004)
J. Biol. Chem
, vol.279
, Issue.12
, pp. 11336-11343
-
-
Stedman, C.1
Robertson, G.2
Coulter, S.3
Liddle, C.4
-
467
-
-
0034669171
-
Role of LXRs in control of lipogenesis
-
Schultz, J.R.; Tu, H.; Luk, A.; Repa, J.J.; Medina, J.C.; Li, L.; Schwendner, S.; Wang, S.; Thoolen, M.; Mangelsdorf, D.J.; Lustig, K.D.; Shan, B. Role of LXRs in control of lipogenesis. Genes Dev., 2000, 14(22), 2831-2838.
-
(2000)
Genes Dev
, vol.14
, Issue.22
, pp. 2831-2838
-
-
Schultz, J.R.1
Tu, H.2
Luk, A.3
Repa, J.J.4
Medina, J.C.5
Li, L.6
Schwendner, S.7
Wang, S.8
Thoolen, M.9
Mangelsdorf, D.J.10
Lustig, K.D.11
Shan, B.12
-
468
-
-
35548949049
-
Gene expression profiling reveals a regulatory role for RORα and RORγ in phase I and phase II metabolism
-
Kang, H.S.; Angers, M.; Beak, J.Y.; Wu, X.; Gimble, J.M.; Wada, T.; Xie, W.; Collins, J.B.; Grissom, S.F.; Jetten, A.M. Gene expression profiling reveals a regulatory role for RORα and RORγ in phase I and phase II metabolism. Physiol. Genomics, 2007, 31(2), 281-294.
-
(2007)
Physiol. Genomics
, vol.31
, Issue.2
, pp. 281-294
-
-
Kang, H.S.1
Angers, M.2
Beak, J.Y.3
Wu, X.4
Gimble, J.M.5
Wada, T.6
Xie, W.7
Collins, J.B.8
Grissom, S.F.9
Jetten, A.M.10
-
469
-
-
54549090146
-
The emerging role of nuclear receptor RORα and its crosstalk with LXR in xeno- and endobiotic gene regulation
-
Wada, T.; Kang, H.S.; Jetten, A.M.; Xie, W. The emerging role of nuclear receptor RORα and its crosstalk with LXR in xeno- and endobiotic gene regulation. Exp. Biol. Med. (Maywood), 2008, 233(10), 1191-1201.
-
(2008)
Exp. Biol. Med. (Maywood)
, vol.233
, Issue.10
, pp. 1191-1201
-
-
Wada, T.1
Kang, H.S.2
Jetten, A.M.3
Xie, W.4
-
470
-
-
44649117324
-
Ligand specificity and evolution of liver X receptors
-
Reschly, E.J.; Ai, N.; Welsh, W.J.; Ekins, S.; Hagey, L.R.; Krasowski, M.D. Ligand specificity and evolution of liver X receptors. J. Steroid Biochem. Mol. Biol., 2008, 110(1-2), 83-94.
-
(2008)
J. Steroid Biochem. Mol. Biol
, vol.110
, Issue.1-2
, pp. 83-94
-
-
Reschly, E.J.1
Ai, N.2
Welsh, W.J.3
Ekins, S.4
Hagey, L.R.5
Krasowski, M.D.6
-
471
-
-
0030036178
-
Genetic analysis of the phenobarbital regulation of the cytochrome P-450 2b-9 and aldehyde dehydrogenase type 2 mRNAs in mouse liver
-
Damon, M.; Fautrel, A.; Marc, N.; Guillouzo, A.; Corcos, L. Genetic analysis of the phenobarbital regulation of the cytochrome P-450 2b-9 and aldehyde dehydrogenase type 2 mRNAs in mouse liver. Biochem. J., 1996, 317(2), 481-486.
-
(1996)
Biochem. J
, vol.317
, Issue.2
, pp. 481-486
-
-
Damon, M.1
Fautrel, A.2
Marc, N.3
Guillouzo, A.4
Corcos, L.5
-
472
-
-
59349085571
-
PXR-mediated induction of human CYP3A4 and mouse Cyp3a11 by the glucocorticoid budesonide
-
Zimmermann, C.; van Waterschoot, R.A.; Harmsen, S.; Maier, A.; Gutmann, H.; Schinkel, A.H. PXR-mediated induction of human CYP3A4 and mouse Cyp3a11 by the glucocorticoid budesonide. Eur. J. Pharm. Sci., 2009, 36(4-5), 565-571.
-
(2009)
Eur. J. Pharm. Sci
, vol.36
, Issue.4-5
, pp. 565-571
-
-
Zimmermann, C.1
van Waterschoot, R.A.2
Harmsen, S.3
Maier, A.4
Gutmann, H.5
Schinkel, A.H.6
-
473
-
-
0032806042
-
Modulation of cytochrome P-450 gene expression in endotoxemic mice is tissue specific and peroxisome proliferator-activated receptor-α dependent
-
Barclay, T.B.; Peters, J.M.; Sewer, M.B.; Ferrari, L.; Gonzalez, F.J.; Morgan E.T. Modulation of cytochrome P-450 gene expression in endotoxemic mice is tissue specific and peroxisome proliferator-activated receptor-α dependent. J. Pharmacol. Exp. Ther., 1999, 290(3), 1250-1257.
-
(1999)
J. Pharmacol. Exp. Ther
, vol.290
, Issue.3
, pp. 1250-1257
-
-
Barclay, T.B.1
Peters, J.M.2
Sewer, M.B.3
Ferrari, L.4
Gonzalez, F.J.5
Morgan, E.T.6
-
474
-
-
33845275122
-
In vitro screening of 200 pesticides for agonistic activity via mouse peroxisome proliferator-activated receptor (PPAR)α and PPARγ and quantitative analysis of in vivo induction pathway
-
Takeuchi, S.; Matsuda, T.; Kobayashi, S.; Takahashi, T.; Kojima, H. In vitro screening of 200 pesticides for agonistic activity via mouse peroxisome proliferator-activated receptor (PPAR)α and PPARγ and quantitative analysis of in vivo induction pathway. Toxicol. Appl. Pharmacol., 2006, 217(3), 235-244.
-
(2006)
Toxicol. Appl. Pharmacol
, vol.217
, Issue.3
, pp. 235-244
-
-
Takeuchi, S.1
Matsuda, T.2
Kobayashi, S.3
Takahashi, T.4
Kojima, H.5
-
475
-
-
22944474949
-
Hepatic cytochrome P450 gene regulation during endotoxin-induced inflammation in nuclear receptor knockout mice
-
Richardson, T.A.; Morgan, E.T. Hepatic cytochrome P450 gene regulation during endotoxin-induced inflammation in nuclear receptor knockout mice. J. Pharmacol. Exp. Ther., 2005, 314(2), 703-709.
-
(2005)
J. Pharmacol. Exp. Ther
, vol.314
, Issue.2
, pp. 703-709
-
-
Richardson, T.A.1
Morgan, E.T.2
-
476
-
-
0038104000
-
Fenofibrate, a ligand for PPARα, inhibits aromatase cytochrome P450 expression in the ovary of mouse
-
Toda, K.; Okada, T.; Miyaura, C.; Saibara, T. Fenofibrate, a ligand for PPARα, inhibits aromatase cytochrome P450 expression in the ovary of mouse. J. Lipid Res., 2003, 44(2), 265-270.
-
(2003)
J. Lipid Res
, vol.44
, Issue.2
, pp. 265-270
-
-
Toda, K.1
Okada, T.2
Miyaura, C.3
Saibara, T.4
-
477
-
-
52949087512
-
Role of vitamin D receptor in the lithocholic acid-mediated CYP3A induction in vitro and in vivo
-
Matsubara, T.; Yoshinari, K.; Aoyama, K.; Sugawara, M.; Sekiya, Y.; Nagata, K.; Yamazoe, Y. Role of vitamin D receptor in the lithocholic acid-mediated CYP3A induction in vitro and in vivo. Drug Metab. Dispos., 2008, 36(10), 2058-2063.
-
(2008)
Drug Metab. Dispos
, vol.36
, Issue.10
, pp. 2058-2063
-
-
Matsubara, T.1
Yoshinari, K.2
Aoyama, K.3
Sugawara, M.4
Sekiya, Y.5
Nagata, K.6
Yamazoe, Y.7
-
478
-
-
0037123667
-
Vitamin D receptor as an intestinal bile acid sensor
-
Makishima, M.; Lu, T.T.; Xie, W.; Whitfield, G.K.; Domoto, H.; Evans, R.M.; Haussler, M.R.; Mangelsdorf, D.J. Vitamin D receptor as an intestinal bile acid sensor. Science, 2002, 296(5571), 1313-1316.
-
(2002)
Science
, vol.296
, Issue.5571
, pp. 1313-1316
-
-
Makishima, M.1
Lu, T.T.2
Xie, W.3
Whitfield, G.K.4
Domoto, H.5
Evans, R.M.6
Haussler, M.R.7
Mangelsdorf, D.J.8
-
479
-
-
34547942910
-
Characterizing early events associated with the activation of target genes by 1,25-dihydroxyvitamin D3 in mouse kidney and intestine in vivo
-
Meyer, M.B.; Zella, L.A.; Nerenz, R.D.; Pike, J.W. Characterizing early events associated with the activation of target genes by 1,25-dihydroxyvitamin D3 in mouse kidney and intestine in vivo. J. Biol. Chem., 2007, 282(31), 22344-22352.
-
(2007)
J. Biol. Chem
, vol.282
, Issue.31
, pp. 22344-22352
-
-
Meyer, M.B.1
Zella, L.A.2
Nerenz, R.D.3
Pike, J.W.4
-
480
-
-
4544356000
-
Regulation of phase I and phase II steroid metabolism enzymes by PPARα activators
-
Fan, L.Q.; You, L.; Brown-Borg, H.; Brown, S.; Edwards, R.J.; Corton, J.C. Regulation of phase I and phase II steroid metabolism enzymes by PPARα activators. Toxicology, 2004, 204(2-3), 109-121.
-
(2004)
Toxicology
, vol.204
, Issue.2-3
, pp. 109-121
-
-
Fan, L.Q.1
You, L.2
Brown-Borg, H.3
Brown, S.4
Edwards, R.J.5
Corton, J.C.6
-
481
-
-
13444311098
-
Role of peroxisome proliferator-activated receptor-α (PPARα) in bezafibrate-induced hepatocarcinogenesis and cholestasis
-
Hays, T.; Rusyn, I.; Burns, A.M.; Kennett, M.J.; Ward, J.M.; Gonzalez, F.J.; Peters, J.M. Role of peroxisome proliferator-activated receptor-α (PPARα) in bezafibrate-induced hepatocarcinogenesis and cholestasis. Carcinogenesis, 2005, 26(1), 219-227.
-
(2005)
Carcinogenesis
, vol.26
, Issue.1
, pp. 219-227
-
-
Hays, T.1
Rusyn, I.2
Burns, A.M.3
Kennett, M.J.4
Ward, J.M.5
Gonzalez, F.J.6
Peters, J.M.7
-
482
-
-
34249724969
-
A novel promoter element containing multiple overlapping xenobiotic and hypoxia response elements mediates induction of cytochrome P4502S1 by both dioxin and hypoxia
-
Rivera, S.P.; Wang, F.; Saarikoski, S.T.; Taylor, R.T.; Chapman, B.; Zhang, R.; Hankinson, O. A novel promoter element containing multiple overlapping xenobiotic and hypoxia response elements mediates induction of cytochrome P4502S1 by both dioxin and hypoxia. J. Biol. Chem., 2007, 282(15), 10881-10893.
-
(2007)
J. Biol. Chem
, vol.282
, Issue.15
, pp. 10881-10893
-
-
Rivera, S.P.1
Wang, F.2
Saarikoski, S.T.3
Taylor, R.T.4
Chapman, B.5
Zhang, R.6
Hankinson, O.7
-
483
-
-
34548628220
-
Chemical proteomic probes for profiling cytochrome P450 activities and drug interactions in vivo
-
Wright, A.T.; Cravatt, B.F. Chemical proteomic probes for profiling cytochrome P450 activities and drug interactions in vivo. Chem. Biol., 2007, 14(9), 1043-1051.
-
(2007)
Chem. Biol
, vol.14
, Issue.9
, pp. 1043-1051
-
-
Wright, A.T.1
Cravatt, B.F.2
-
484
-
-
0031741875
-
Interactions of gender, growth hormone, and phenobarbital induction on murine Cyp2b expression
-
Sharma, M.C.; Agrawal, A.K.; Sharma, M.R.; Shapiro, B.H. Interactions of gender, growth hormone, and phenobarbital induction on murine Cyp2b expression. Biochem. Pharmacol., 1998, 56(9), 1251-1258.
-
(1998)
Biochem. Pharmacol
, vol.56
, Issue.9
, pp. 1251-1258
-
-
Sharma, M.C.1
Agrawal, A.K.2
Sharma, M.R.3
Shapiro, B.H.4
-
485
-
-
0037683599
-
-
Fukuzawa, N.H.; Ohsako, S.; Nagano, R.; Sakaue, M.; Baba, T.; Aoki, Y.; Tohyama, C. Effects of 3,3',4,4',5-pentachlorobiphenyl, a coplanar polychlorinated biphenyl congener, on cultured neonatal mouse testis. Toxicol. In Vitro, 2003, 17(3), 259-269.
-
Fukuzawa, N.H.; Ohsako, S.; Nagano, R.; Sakaue, M.; Baba, T.; Aoki, Y.; Tohyama, C. Effects of 3,3',4,4',5-pentachlorobiphenyl, a coplanar polychlorinated biphenyl congener, on cultured neonatal mouse testis. Toxicol. In Vitro, 2003, 17(3), 259-269.
-
-
-
-
486
-
-
0015868089
-
Microsomal-catalyzed hydroperoxide-dependent C-oxidation of amines
-
Kadlubar, F.F.; Morton, K.C.; Ziegler, D.M. Microsomal-catalyzed hydroperoxide-dependent C-oxidation of amines. Biochem. Biophys. Res. Commun., 1973, 54(4), 1255-1261.
-
(1973)
Biochem. Biophys. Res. Commun
, vol.54
, Issue.4
, pp. 1255-1261
-
-
Kadlubar, F.F.1
Morton, K.C.2
Ziegler, D.M.3
-
487
-
-
0018152007
-
The mechanism of action of cytochrome P-450. Occurrence of the 'NIH shift' during hydroperoxide-dependent aromatic hydroxylations
-
Rahimtula, A.D.; O'Brien, P.J.; Seifried, H.E.; Jerina, D.M. The mechanism of action of cytochrome P-450. Occurrence of the 'NIH shift' during hydroperoxide-dependent aromatic hydroxylations. Eur. J. Biochem., 1978, 89(1), 133-141.
-
(1978)
Eur. J. Biochem
, vol.89
, Issue.1
, pp. 133-141
-
-
Rahimtula, A.D.1
O'Brien, P.J.2
Seifried, H.E.3
Jerina, D.M.4
-
488
-
-
70350434097
-
Functional characterization of human cytochrome P450 2S1 using a synthetic gene-expressed protein in Escherichia coli
-
Bui, P.H.; Hankinson, O. Functional characterization of human cytochrome P450 2S1 using a synthetic gene-expressed protein in Escherichia coli. Mol. Pharmacol., 2009, 76(5), 1031-1043.
-
(2009)
Mol. Pharmacol
, vol.76
, Issue.5
, pp. 1031-1043
-
-
Bui, P.H.1
Hankinson, O.2
-
489
-
-
70350455899
-
Fatty acid hydroperoxides support cytochrome P450 2S1-mediated bioactivation of benzo[a]pyrene-7,8- dihydrodiol
-
Bui, P.H.; Hsu, E.L.; Hankinson, O. Fatty acid hydroperoxides support cytochrome P450 2S1-mediated bioactivation of benzo[a]pyrene-7,8- dihydrodiol. Mol. Pharmacol., 2009, 76(5), 1044-1052.
-
(2009)
Mol. Pharmacol
, vol.76
, Issue.5
, pp. 1044-1052
-
-
Bui, P.H.1
Hsu, E.L.2
Hankinson, O.3
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