-
1
-
-
0031831381
-
Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines
-
Hecht,S.S. (1998) Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines. Chem. Res. Toxicol., 11, 559-603.
-
(1998)
Chem. Res. Toxicol.
, vol.11
, pp. 559-603
-
-
Hecht, S.S.1
-
2
-
-
0030938094
-
The changing cigarette, 1950-1995
-
Hoffmann,D. and Hoffmann,I. (1997) The changing cigarette, 1950-1995. J. Toxicol. Environ. Health, 50, 307-364.
-
(1997)
J. Toxicol. Environ. Health
, vol.50
, pp. 307-364
-
-
Hoffmann, D.1
Hoffmann, I.2
-
3
-
-
0033591845
-
Tobacco smoke carcinogens and lung cancer
-
Hecht,S.S. (1999) Tobacco smoke carcinogens and lung cancer. J. Natl Cancer Inst., 91, 1194-1210.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 1194-1210
-
-
Hecht, S.S.1
-
4
-
-
0036333198
-
Cigarette smoking and lung cancer: Chemical mechanisms and approaches to prevention
-
Hecht,S.S. (2002) Cigarette smoking and lung cancer: Chemical mechanisms and approaches to prevention. Lancet Oncol., 3, 461-469.
-
(2002)
Lancet Oncol.
, vol.3
, pp. 461-469
-
-
Hecht, S.S.1
-
5
-
-
0025848338
-
A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl) -1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6
-
Crespi,C.L., Penman,B.W., Gelboin,H.V. and Gonzalez,F.J. (1991) A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6. Carcinogenesis, 12, 1197-1201.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1197-1201
-
-
Crespi, C.L.1
Penman, B.W.2
Gelboin, H.V.3
Gonzalez, F.J.4
-
6
-
-
0025925258
-
6-methylguanine is a critical determinant of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenesis in A/J mouse lung
-
6-methylguanine is a critical determinant of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenesis in A/J mouse lung. Cancer Res., 51, 5557-5564.
-
(1991)
Cancer Res.
, vol.51
, pp. 5557-5564
-
-
Peterson, L.A.1
Hecht, S.S.2
-
7
-
-
0027333129
-
G to A transitions and G to T transversions in codon 12 of the Ki-ras oncogene isolated from mouse lung tumors induced by 4-(methylnitrosamino) -1-(3-pyridyl)-1-butanone (NNK) and related DNA methylating and pyridyloxobutylating agents
-
Ronai,Z.A., Gradia,S., Peterson,L.A. and Hecht,S.S. (1993) G to A transitions and G to T transversions in codon 12 of the Ki-ras oncogene isolated from mouse lung tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and related DNA methylating and pyridyloxobutylating agents. Carcinogenesis, 14, 2419-2422.
-
(1993)
Carcinogenesis
, vol.14
, pp. 2419-2422
-
-
Ronai, Z.A.1
Gradia, S.2
Peterson, L.A.3
Hecht, S.S.4
-
8
-
-
0025784027
-
Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms
-
Porter,T.D. and Coon,M.J. (1991) Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms. J. Biol. Chem., 266, 13469-13472.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 13469-13472
-
-
Porter, T.D.1
Coon, M.J.2
-
9
-
-
0027446505
-
The P450 superfamily: Update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature
-
Nelson,D.R., Kamataki,T., Waxman,D.J., Guengerich,F.P., Estabrook,R.W., Feyereisen,R., Gonzalez,F.J., Coon,M.J., Gunsalus,I.C., Gotoh,O., Okuda,K. and Nebert,D.W. (1993) The P450 superfamily: Update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. DNA Cell. Biol., 12, 1-51.
-
(1993)
DNA Cell. Biol.
, vol.12
, pp. 1-51
-
-
Nelson, D.R.1
Kamataki, T.2
Waxman, D.J.3
Guengerich, F.P.4
Estabrook, R.W.5
Feyereisen, R.6
Gonzalez, F.J.7
Coon, M.J.8
Gunsalus, I.C.9
Gotoh, O.10
Okuda, K.11
Nebert, D.W.12
-
10
-
-
9044254525
-
P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
-
Nelson,D.R., Koymans,L., Kamataki,T., Stegeman,J.J., Feyereisen,R., Waxman,D.J., Waterman,M.R., Gotoh,O., Coon,M.J., Estabrook,R.W., Gunsalus,I.C. and Nebert,D.W. (1996) P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics, 6, 1-42.
-
(1996)
Pharmacogenetics
, vol.6
, pp. 1-42
-
-
Nelson, D.R.1
Koymans, L.2
Kamataki, T.3
Stegeman, J.J.4
Feyereisen, R.5
Waxman, D.J.6
Waterman, M.R.7
Gotoh, O.8
Coon, M.J.9
Estabrook, R.W.10
Gunsalus, I.C.11
Nebert, D.W.12
-
11
-
-
0025992864
-
Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes
-
Guengerich,F.P. and Shimada,T. (1991) Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes. Chem. Res. Toxicol., 4, 391-407.
-
(1991)
Chem. Res. Toxicol.
, vol.4
, pp. 391-407
-
-
Guengerich, F.P.1
Shimada, T.2
-
12
-
-
0034973773
-
Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity
-
Guengerich,F.P. (2001) Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity. Chem. Res. Toxicol., 14, 611-650.
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 611-650
-
-
Guengerich, F.P.1
-
13
-
-
0024344176
-
cDNA and deduced amino acid sequences of human P450 IIA3 (CYP2A3)
-
Yamano,S., Nagata,K., Yamazoe,Y., Kato,R., Gelboin,H.V. and Gonzalez,F.J. (1989) cDNA and deduced amino acid sequences of human P450 IIA3 (CYP2A3). Nucleic Acids Res., 17, 4888.
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 4888
-
-
Yamano, S.1
Nagata, K.2
Yamazoe, Y.3
Kato, R.4
Gelboin, H.V.5
Gonzalez, F.J.6
-
14
-
-
0032077398
-
Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues
-
Mace,K., Bowman,E.D., Vautravers,P., Shields,P.G., Harris,C.C. and Pfeifer,A.M. (1998) Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues. Eur. J. Cancer, 34, 914-920.
-
(1998)
Eur. J. Cancer
, vol.34
, pp. 914-920
-
-
Mace, K.1
Bowman, E.D.2
Vautravers, P.3
Shields, P.G.4
Harris, C.C.5
Pfeifer, A.M.6
-
15
-
-
0031708963
-
Measurement of cytochrome P450 2A6 and 2E1 gene expression in primary human bronchial epithelial cells
-
Crawford,E.L., Weaver,D.A., DeMuth,J.P., Jackson,C.M., Khuder,S.A., Frampton,M.W., Utell,M.J., Thilly,W.G. and Willey,J.C. (1998) Measurement of cytochrome P450 2A6 and 2E1 gene expression in primary human bronchial epithelial cells. Carcinogenesis, 19, 1867-1871.
-
(1998)
Carcinogenesis
, vol.19
, pp. 1867-1871
-
-
Crawford, E.L.1
Weaver, D.A.2
DeMuth, J.P.3
Jackson, C.M.4
Khuder, S.A.5
Frampton, M.W.6
Utell, M.J.7
Thilly, W.G.8
Willey, J.C.9
-
16
-
-
0026744568
-
Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes
-
Yamazaki,H., Inui,Y., Yun,C.H., Guengerich,F.P. and Shimada,T. (1992) Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes. Carcinogenesis, 13, 1789-1794.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1789-1794
-
-
Yamazaki, H.1
Inui, Y.2
Yun, C.H.3
Guengerich, F.P.4
Shimada, T.5
-
17
-
-
0034122382
-
Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH-cytochrome P450 reductase
-
Kushida,H., Fujita,K., Suzuki,A., Yamada,M., Endo,T., Nohmi,T. and Kamataki,T. (2000) Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH-cytochrome P450 reductase. Carcinogenesis, 21, 1227-1232.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1227-1232
-
-
Kushida, H.1
Fujita, K.2
Suzuki, A.3
Yamada, M.4
Endo, T.5
Nohmi, T.6
Kamataki, T.7
-
18
-
-
0029099107
-
A genetic polymorphism in coumarin 7-hydroxylation: Sequence of the human CYP2A genes and identification of variant CYP2A6 allele
-
Fernandez-Salguero,P., Hoffman,S., Cholerton,S., Mohrenweiser,H., Raunio,H., Rautio,A., Pelkonen,O., Huang,J., Evans,W., Idle,J. and Gonzalez,F.J. (1995) A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 allele. Am. J. Hum. Genet., 57, 651-660.
-
(1995)
Am. J. Hum. Genet.
, vol.57
, pp. 651-660
-
-
Fernandez-Salguero, P.1
Hoffman, S.2
Cholerton, S.3
Mohrenweiser, H.4
Raunio, H.5
Rautio, A.6
Pelkonen, O.7
Huang, J.8
Evans, W.9
Idle, J.10
Gonzalez, F.J.11
-
19
-
-
0036260293
-
Variation in coumarin 7-hydroxylase activity associated with genetic polymorphism of cytochrome P450 2A6 and the body status of iron stores in adult Thai males and females
-
Ujjin,P., Satarug,S., Vanavanitkun,Y., Daigo,S., Ariyoshi,N., Yamazaki,H., Reilly,P.E., Moore,M.R. and Kamataki,T. (2002) Variation in coumarin 7-hydroxylase activity associated with genetic polymorphism of cytochrome P450 2A6 and the body status of iron stores in adult Thai males and females. Pharmacogenetics, 12, 241-249.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 241-249
-
-
Ujjin, P.1
Satarug, S.2
Vanavanitkun, Y.3
Daigo, S.4
Ariyoshi, N.5
Yamazaki, H.6
Reilly, P.E.7
Moore, M.R.8
Kamataki, T.9
-
20
-
-
7144257874
-
A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+) -cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502)
-
Nunoya,K., Yokoi,T., Kimura,K., Inoue,K., Kodama,T., Funayama,M., Nagashima,K., Funae,Y., Green,C., Kinoshita,M. and Kamataki,T. (1998) A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502). Pharmacogenetics, 8, 239-249.
-
(1998)
Pharmacogenetics
, vol.8
, pp. 239-249
-
-
Nunoya, K.1
Yokoi, T.2
Kimura, K.3
Inoue, K.4
Kodama, T.5
Funayama, M.6
Nagashima, K.7
Funae, Y.8
Green, C.9
Kinoshita, M.10
Kamataki, T.11
-
21
-
-
0032945691
-
A new CYP2A6 gene deletion responsible for the in vivo polymorphic metabolism of (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride in humans
-
Nunoya,K.I., Yokoi,T., Kimura,K., Kainuma,T., Satoh,K., Kinoshita,M. and Kamataki,T. (1999) A new CYP2A6 gene deletion responsible for the in vivo polymorphic metabolism of (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride in humans. J. Pharmacol. Exp. Ther., 289, 437-442.
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.289
, pp. 437-442
-
-
Nunoya, K.I.1
Yokoi, T.2
Kimura, K.3
Kainuma, T.4
Satoh, K.5
Kinoshita, M.6
Kamataki, T.7
-
22
-
-
0034805710
-
A novel single nucleotide polymorphism altering stability and activity of CYP2A6
-
Ariyoshi,N., Sawamura,Y. and Kamataki,T. (2001) A novel single nucleotide polymorphism altering stability and activity of CYP2A6. Biochem. Biophys. Res. Commun., 281, 810-814.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.281
, pp. 810-814
-
-
Ariyoshi, N.1
Sawamura, Y.2
Kamataki, T.3
-
23
-
-
0036016314
-
A novel mutant allele of the CYP2A6 gene (CYP2A6*11) found in a cancer patient who showed poor metabolic phenotype towards tegafur
-
Daigo,S., Takahashi,Y., Fujieda,M., Ariyoshi,N., Yamazaki,H., Koizumi,W., Tanabe,S., Nagayama,S., Ikeda,K., Nishioka,Y. and Kamataki,T. (2002) A novel mutant allele of the CYP2A6 gene (CYP2A6*11) found in a cancer patient who showed poor metabolic phenotype towards tegafur. Pharmacogenetics, 12, 299-306.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 299-306
-
-
Daigo, S.1
Takahashi, Y.2
Fujieda, M.3
Ariyoshi, N.4
Yamazaki, H.5
Koizumi, W.6
Tanabe, S.7
Nagayama, S.8
Ikeda, K.9
Nishioka, Y.10
Kamataki, T.11
-
24
-
-
0033546744
-
CYP2A6 gene deletion reduces susceptibility to lung cancer
-
Miyamoto,M., Umetsu,Y., Dosaka-Akita,H., Sawamura,Y., Yokota,J., Kunitoh,H., Nemoto,N., Sato,K., Ariyoshi,N. and Kamataki,T. (1999) CYP2A6 gene deletion reduces susceptibility to lung cancer. Biochem. Biophys. Res. Commun., 261, 658-660.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.261
, pp. 658-660
-
-
Miyamoto, M.1
Umetsu, Y.2
Dosaka-Akita, H.3
Sawamura, Y.4
Yokota, J.5
Kunitoh, H.6
Nemoto, N.7
Sato, K.8
Ariyoshi, N.9
Kamataki, T.10
-
25
-
-
0036716809
-
Genetic polymorphism of CYP2A6 gene and tobacco-induced lung cancer risk in male smokers
-
Ariyoshi,N., Miyamoto,M., Umetsu,Y., Kunitoh,H., Dosaka-Akita,H., Sawamura,Y., Yokota,J., Nemoto,N., Sato,K. and Kamataki,T. (2002) Genetic polymorphism of CYP2A6 gene and tobacco-induced lung cancer risk in male smokers. Cancer Epidemiol. Biomarkers Prev., 11, 890-894.
-
(2002)
Cancer Epidemiol. Biomarkers Prev.
, vol.11
, pp. 890-894
-
-
Ariyoshi, N.1
Miyamoto, M.2
Umetsu, Y.3
Kunitoh, H.4
Dosaka-Akita, H.5
Sawamura, Y.6
Yokota, J.7
Nemoto, N.8
Sato, K.9
Kamataki, T.10
-
26
-
-
10344238546
-
Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers
-
Fujieda,M., Yamazaki,H., Saito,T., Kiyotani,K., Gyramfi,M., Sakurai,M., Dosaka-Akita,H., Sawamura,Y., Yokota,J., Kunitoh,H. and Kamataki,T. (2004) Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers. Carcinogenesis, 25, 2451-2458.
-
(2004)
Carcinogenesis
, vol.25
, pp. 2451-2458
-
-
Fujieda, M.1
Yamazaki, H.2
Saito, T.3
Kiyotani, K.4
Gyramfi, M.5
Sakurai, M.6
Dosaka-Akita, H.7
Sawamura, Y.8
Yokota, J.9
Kunitoh, H.10
Kamataki, T.11
-
27
-
-
0017039768
-
Molecular and genetic basis of furocoumarin reactions
-
Scott,B.R., Pathak,M.A. and Mohn,G.R. (1976) Molecular and genetic basis of furocoumarin reactions. Mutat. Res., 39, 29-74.
-
(1976)
Mutat. Res.
, vol.39
, pp. 29-74
-
-
Scott, B.R.1
Pathak, M.A.2
Mohn, G.R.3
-
28
-
-
0017642367
-
Oral methoxsalen photochemotherapy for the treatment of psoriasis: A cooperative clinical trial
-
Melski,J.W., Tanenbaum,L., Parrish,J.A., Fitzpatrick,T.B. and Bleich,H.L. (1977) Oral methoxsalen photochemotherapy for the treatment of psoriasis: A cooperative clinical trial. J. Invest. Dermatol., 68, 329-335.
-
(1977)
J. Invest. Dermatol.
, vol.68
, pp. 329-335
-
-
Melski, J.W.1
Tanenbaum, L.2
Parrish, J.A.3
Fitzpatrick, T.B.4
Bleich, H.L.5
-
29
-
-
0016385502
-
Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light
-
Parrish,J.A., Fitzpatrick,T.B., Tanenbaum,L. and Pathak,M.A. (1974) Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light. N. Engl. J. Med., 291, 1207-1211.
-
(1974)
N. Engl. J. Med.
, vol.291
, pp. 1207-1211
-
-
Parrish, J.A.1
Fitzpatrick, T.B.2
Tanenbaum, L.3
Pathak, M.A.4
-
30
-
-
0031451433
-
Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen
-
Koenigs,L.L., Peter,R.M., Thompson,S.J., Rettie,A.E. and Trager,W.F. (1997) Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen. Drug Metab. Dispos., 25, 1407-1415.
-
(1997)
Drug Metab. Dispos.
, vol.25
, pp. 1407-1415
-
-
Koenigs, L.L.1
Peter, R.M.2
Thompson, S.J.3
Rettie, A.E.4
Trager, W.F.5
-
31
-
-
0027537370
-
Differential inhibition of coumarin 7-hydroxylase activity in mouse and human liver microsomes
-
Maenpaa,J., Sigusch,H., Raunio,H., Syngelma,T., Vuorela,P., Vuorela,H. and Pelkonen,O. (1993) Differential inhibition of coumarin 7-hydroxylase activity in mouse and human liver microsomes. Biochem. Pharmacol., 45, 1035-1042.
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 1035-1042
-
-
Maenpaa, J.1
Sigusch, H.2
Raunio, H.3
Syngelma, T.4
Vuorela, P.5
Vuorela, H.6
Pelkonen, O.7
-
32
-
-
0028075688
-
Catalytic roles of rat and human cytochrome P450 2A enzymes in testosterone 7α -and coumarin 7-hydroxylations
-
Yamazaki,H., Mimura,M., Sugahara,C. and Shimada,T. (1994) Catalytic roles of rat and human cytochrome P450 2A enzymes in testosterone 7α -and coumarin 7-hydroxylations. Biochem. Pharmacol., 48, 1524-1527.
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 1524-1527
-
-
Yamazaki, H.1
Mimura, M.2
Sugahara, C.3
Shimada, T.4
-
33
-
-
0344844480
-
Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino) -1-(3-pyridyl)-1-butanone in female A/J mice
-
Takeuchi,H., Saoo,K., Yokohira,M., Ikeda,M., Maeta,H., Miyazaki,M., Yamazaki,H., Kamataki,J. and Imaida,K. (2003) Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice. Cancer Res., 63, 7581-7583.
-
(2003)
Cancer Res.
, vol.63
, pp. 7581-7583
-
-
Takeuchi, H.1
Saoo, K.2
Yokohira, M.3
Ikeda, M.4
Maeta, H.5
Miyazaki, M.6
Yamazaki, H.7
Kamataki, J.8
Imaida, K.9
-
34
-
-
0035681393
-
Construction of Salmonella typhimurium YG7108 strains, each coexpressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase
-
Fujita Ki,K., Nakayama,K., Yamazaki,Y., Tsuruma,K., Yamada,M., Nohmi,T. and Kamataki,T. (2001) Construction of Salmonella typhimurium YG7108 strains, each coexpressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase. Environ. Mol. Mutagen., 38, 329-338.
-
(2001)
Environ. Mol. Mutagen.
, vol.38
, pp. 329-338
-
-
Fujita Ki, K.1
Nakayama, K.2
Yamazaki, Y.3
Tsuruma, K.4
Yamada, M.5
Nohmi, T.6
Kamataki, T.7
-
35
-
-
50449100139
-
The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
-
Omura,T. and Sato,R. (1964) The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J. Biol. Chem., 239, 2379-2385.
-
(1964)
J. Biol. Chem.
, vol.239
, pp. 2379-2385
-
-
Omura, T.1
Sato, R.2
-
36
-
-
73849173955
-
Hepatic triphosphopyridine nucleotide (TPN)-cytochrome c reductase: Isolation, characterization and kinetic studies
-
Phillips,A.H. and Langdon,R.G. (1962) Hepatic triphosphopyridine nucleotide (TPN)-cytochrome c reductase: Isolation, characterization and kinetic studies. J. Biol. Chem., 237, 2652-2660.
-
(1962)
J. Biol. Chem.
, vol.237
, pp. 2652-2660
-
-
Phillips, A.H.1
Langdon, R.G.2
-
37
-
-
0020533372
-
Revised methods for the Salmonella mutagenicity test
-
Maron,D.M. and Ames,B.N. (1983) Revised methods for the Salmonella mutagenicity test. Mutat. Res., 113, 173-215.
-
(1983)
Mutat. Res.
, vol.113
, pp. 173-215
-
-
Maron, D.M.1
Ames, B.N.2
-
38
-
-
0002254766
-
Analysis and characterization of enzyme
-
Hayes,A.W. (ed.), Raven Press, NY
-
Guengerich,F. (1994) Analysis and characterization of enzyme. In: Hayes,A.W. (ed.), Principles and Methods of Toxicology. Raven Press, NY, pp. 1259-1313.
-
(1994)
Principles and Methods of Toxicology
, pp. 1259-1313
-
-
Guengerich, F.1
-
39
-
-
0030337799
-
A new transgenic mouse mutagenesis test system using Spi- and 6-thioguanine selections
-
Nohmi,T., Katoh,M., Suzuki,H., Matsui,M., Yamada,M., Watanabe,M., Suzuki,M., Horiya,N., Ueda,O., Shibuya,T., Ikeda,H. and Sofuni,T. (1996) A new transgenic mouse mutagenesis test system using Spi- and 6-thioguanine selections. Environ. Mol. Mutagen., 28, 465-470.
-
(1996)
Environ. Mol. Mutagen.
, vol.28
, pp. 465-470
-
-
Nohmi, T.1
Katoh, M.2
Suzuki, H.3
Matsui, M.4
Yamada, M.5
Watanabe, M.6
Suzuki, M.7
Horiya, N.8
Ueda, O.9
Shibuya, T.10
Ikeda, H.11
Sofuni, T.12
-
40
-
-
0345432986
-
Tumors of the lungs
-
Turusov,V.S. and Mohrs,U. (eds), Tumours of the Mouse. Lyon
-
Rehm,S., Word,J. and Sass,B. (1994) Tumors of the lungs. In: Turusov,V.S. and Mohrs,U. (eds), Pathology of Tumors in Laboratory Animals, Vol. 2, Tumours of the Mouse. Lyon, pp. 325-355.
-
(1994)
Pathology of Tumors in Laboratory Animals
, vol.2
, pp. 325-355
-
-
Rehm, S.1
Word, J.2
Sass, B.3
-
41
-
-
0025133114
-
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates
-
Smith,T.J., Guo,Z.Y., Thomas,P.E., Chung,F.L., Morse,M.A., Elkind,K. and Yang,C.S. (1990) Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates. Cancer Res., 50, 6817-6822.
-
(1990)
Cancer Res.
, vol.50
, pp. 6817-6822
-
-
Smith, T.J.1
Guo, Z.Y.2
Thomas, P.E.3
Chung, F.L.4
Morse, M.A.5
Elkind, K.6
Yang, C.S.7
-
42
-
-
0026425564
-
Metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone as measured by DNA alkylation in vitro and its inhibition by isothiocyanates
-
Guo,Z., Smith,T.J., Thomas,P.E. and Yang,C.S. (1991) Metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone as measured by DNA alkylation in vitro and its inhibition by isothiocyanates. Cancer Res., 51, 4798-4803.
-
(1991)
Cancer Res.
, vol.51
, pp. 4798-4803
-
-
Guo, Z.1
Smith, T.J.2
Thomas, P.E.3
Yang, C.S.4
-
43
-
-
0026741674
-
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells
-
Smith,T.J., Guo,Z., Gonzalez,F.J., Guengerich,F.P., Stoner,G.D. and Yang,C.S. (1992) Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells. Cancer Res., 52, 1757-1763.
-
(1992)
Cancer Res.
, vol.52
, pp. 1757-1763
-
-
Smith, T.J.1
Guo, Z.2
Gonzalez, F.J.3
Guengerich, F.P.4
Stoner, G.D.5
Yang, C.S.6
-
44
-
-
0026793493
-
Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa
-
Smith,T.J., Guo,Z., Hong,J.Y., Ning,S.M., Thomas,P.E. and Yang,C.S. (1992) Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa. Carcinogenesis, 13, 1409-1414.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1409-1414
-
-
Smith, T.J.1
Guo, Z.2
Hong, J.Y.3
Ning, S.M.4
Thomas, P.E.5
Yang, C.S.6
-
45
-
-
0022403303
-
Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation
-
Burkhart,B.A., Harada,N. and Negishi,M. (1985) Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation. J. Biol. Chem., 260, 15357-15361.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 15357-15361
-
-
Burkhart, B.A.1
Harada, N.2
Negishi, M.3
-
46
-
-
0021744242
-
Purification and characterization of a microsoma] cytochrome P-450 with high activity of coumarin 7-hydroxylase from mouse liver
-
Kaipainen,P., Nebert,D.W. and Lang,M.A. (1984) Purification and characterization of a microsoma] cytochrome P-450 with high activity of coumarin 7-hydroxylase from mouse liver. Eur. J. Biochem., 144, 425-431.
-
(1984)
Eur. J. Biochem.
, vol.144
, pp. 425-431
-
-
Kaipainen, P.1
Nebert, D.W.2
Lang, M.A.3
-
47
-
-
0023872208
-
Purification and characterization of a liver microsomal cytochrome P-450 isoenzyme with a high affinity and metabolic capacity for coumarin from pyrazole-treated D2 mice
-
Juvonen,R.O., Shkumatov,V.M. and Lang,M.A. (1988) Purification and characterization of a liver microsomal cytochrome P-450 isoenzyme with a high affinity and metabolic capacity for coumarin from pyrazole-treated D2 mice. Eur. J. Biochem., 171, 205-211.
-
(1988)
Eur. J. Biochem.
, vol.171
, pp. 205-211
-
-
Juvonen, R.O.1
Shkumatov, V.M.2
Lang, M.A.3
-
48
-
-
0027175349
-
Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): Role of residue-209 in determining steroid-cytochrome P-450 interaction
-
Iwasaki,M., Lindberg,R.L., Juvonen,R.O. and Negishi,M. (1993) Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): Role of residue-209 in determining steroid-cytochrome P-450 interaction. Biochem. J., 291, 569-573.
-
(1993)
Biochem. J.
, vol.291
, pp. 569-573
-
-
Iwasaki, M.1
Lindberg, R.L.2
Juvonen, R.O.3
Negishi, M.4
-
50
-
-
0031427202
-
The structure, function, and regulation of cytochrome P450 2A enzymes
-
Honkakoski,P. and Negishi,M. (1997) The structure, function, and regulation of cytochrome P450 2A enzymes. Drug Metab. Rev., 29, 977-996.
-
(1997)
Drug Metab. Rev.
, vol.29
, pp. 977-996
-
-
Honkakoski, P.1
Negishi, M.2
-
51
-
-
0036746746
-
In vivo effect of 5- and 8-methoxypsoralens and cimetidine on R,S-warfarin metabolism in rat
-
Szutowski,M., Lukasik,M., Wawer,Z., Chrobak,K., Michalska,M., Borzecka,K. and Brzezinski,J. (2002) In vivo effect of 5- and 8-methoxypsoralens and cimetidine on R,S-warfarin metabolism in rat. J. Appl. Toxicol., 22, 327-332.
-
(2002)
J. Appl. Toxicol.
, vol.22
, pp. 327-332
-
-
Szutowski, M.1
Lukasik, M.2
Wawer, Z.3
Chrobak, K.4
Michalska, M.5
Borzecka, K.6
Brzezinski, J.7
-
52
-
-
0030056594
-
Specificity of substrate and inhibitor probes for cytochrome P450s: Evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes
-
Ono,S., Hatanaka,T., Hotta,H., Satoh,T., Gonzalez,F.J. and Tsutsui,M. (1996) Specificity of substrate and inhibitor probes for cytochrome P450s: Evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes. Xenobiotica, 26, 681-693.
-
(1996)
Xenobiotica
, vol.26
, pp. 681-693
-
-
Ono, S.1
Hatanaka, T.2
Hotta, H.3
Satoh, T.4
Gonzalez, F.J.5
Tsutsui, M.6
-
53
-
-
0031149716
-
Inhibition of coumarin 7-hydroxylase activity in human liver microsomes
-
Draper,A.J., Madan,A. and Parkinson,A. (1997) Inhibition of coumarin 7-hydroxylase activity in human liver microsomes. Arch. Biochem. Biophys., 341, 47-61.
-
(1997)
Arch. Biochem. Biophys.
, vol.341
, pp. 47-61
-
-
Draper, A.J.1
Madan, A.2
Parkinson, A.3
-
54
-
-
0033960956
-
Sinple-dose methoxsalen effects on human cytochrome P-450 2A6 activity
-
Kharasch,E.D., Hankins,D.C. and Taraday,J.K. (2000) Sinple-dose methoxsalen effects on human cytochrome P-450 2A6 activity. Drug Metab. Dispos., 28, 28-33.
-
(2000)
Drug Metab. Dispos.
, vol.28
, pp. 28-33
-
-
Kharasch, E.D.1
Hankins, D.C.2
Taraday, J.K.3
-
55
-
-
0035133407
-
Mutagenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl) -1-butanone-4-(methylnitrosamino)-1-(3-pyridiyl)-1-butanone and N-nitrosonornicotine in lacZ upper aerodigestive tissue and liver and inhibition by green tea
-
von Pressentin,M.M., Chen,M. and Guttenplan,J.B. (2001) Mutagenesis induced by
-
(2001)
Carcinogenesis
, vol.22
, pp. 203-206
-
-
von Pressentin, M.M.1
Chen, M.2
Guttenplan, J.B.3
-
56
-
-
0020647231
-
Tissue distribution of tobacco-specific carcinogen 4-(methylnitrosamino) -1-(3-pyridyl)-1-butanone (NNK) and its metabolites in F344 rats
-
Castonguay,A., Tjalve,H. and Hecht,S.S. (1983) Tissue distribution of tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and its metabolites in F344 rats. Cancer Res., 43, 630-638.
-
(1983)
Cancer Res.
, vol.43
, pp. 630-638
-
-
Castonguay, A.1
Tjalve, H.2
Hecht, S.S.3
-
57
-
-
13844256200
-
Mutagenic activation of betel quid-specific N-nitrosamines catalyzed by human cytochrome P450 coexpressed with NADPH-cytochrome P450 reductase in Salmonella typhimurium YG7108
-
Miyazaki,M., Sugawara,E., Yoshimura,T., Yamazaki,H. and Kamataki,T. (2005) Mutagenic activation of betel quid-specific N-nitrosamines catalyzed by human cytochrome P450 coexpressed with NADPH-cytochrome P450 reductase in Salmonella typhimurium YG7108. Mutat. Res., 581, 165-171.
-
(2005)
Mutat. Res.
, vol.581
, pp. 165-171
-
-
Miyazaki, M.1
Sugawara, E.2
Yoshimura, T.3
Yamazaki, H.4
Kamataki, T.5
-
58
-
-
0036257167
-
CYP2A6 gene deletion reduces oral cancer risk in betel quid chewers in Sri Lanka
-
Topcu,Z., Chiba,I., Fujieda,M., Shibata,T., Ariyoshi,N., Yamazaki,H., Sevgican,F., Muthumala,M., Kobayashi,H, and Kamataki,T. (2002) CYP2A6 gene deletion reduces oral cancer risk in betel quid chewers in Sri Lanka. Carcinogenesis, 23, 595-598.
-
(2002)
Carcinogenesis
, vol.23
, pp. 595-598
-
-
Topcu, Z.1
Chiba, I.2
Fujieda, M.3
Shibata, T.4
Ariyoshi, N.5
Yamazaki, H.6
Sevgican, F.7
Muthumala, M.8
Kobayashi, H.9
Kamataki, T.10
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