Distribution of cytochrome P-450 4A and 4F isoforms along the nephron in mice

American Journal of Physiology - Renal Physiology

Volumn 284, Issue 1 53-1, 2003, Pages

  Stec, David E ^a   Flasch, Averia ^b   Roman, Richard J ^b   White, Jared A ^a  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

20 hydroxyeicosatetraenoic acid; Cytochome P 450 4A isoforms; Cytochrome P 450 4F isoforms; Microdissection; Mouse; Nephron segment; Reverse transcription polymerase chain reaction

Indexed keywords

20 HYDROXYICOSATETRAENOIC ACID; CYTOCHROME P450 4A; CYTOCHROME P450 4A10; CYTOCHROME P450 4A12; CYTOCHROME P450 4F; CYTOCHROME P450 4F13; CYTOCHROME P450 4F14; CYTOCHROME P450 4F15; CYTOCHROME P450 4F16; CYTOCHROME P450 4F18; CYTOCHROME P450 ISOENZYME; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BLOOD VESSEL TONE; CELL SPECIFICITY; CELL TYPE; CHLORIDE TRANSPORT; ENZYME LOCALIZATION; FEMALE; GENE DISRUPTION; GLOMERULUS; KIDNEY BLOOD VESSEL; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE ABSORPTION; MALE; MOLECULAR GENETICS; MOUSE; NEPHRON; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SEX DIFFERENCE; SODIUM ABSORPTION; TISSUE DISTRIBUTION;

EID: 0037215134     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00132.2002     Document Type: Article

References (31)

1. Alonso-Galicia M, Maier KG, Greene AS, Cowley AW Jr, and Roman RJ. Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II. Am J Physiol Regul Integr Comp Physiol 283: R60-R68, 2002.
2. Bell DR, Plant NJ, Rider CG, Na L, Brown S, Ateitalla I, Acharya SK, Davies MH, Elias E, and Jenkins NA. Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs. Biochem J 294: 173-180, 1993.
3. Bylund J, Bylund M, and Oliw EH. cDna cloning and expression of CYP4F12, a novel human cytochrome P-450. Biochem Biophys Res Commun 280: 892-897, 2001.
4. Christmas P, Jones JP, Patten CJ, Rock DA, Zheng YM, Cheng SM, Weber BM, Carlesso N, Scadden DT, Rettie AE, and Soberman RJ. Alternative splicing determines the function of CYP4F3 by switching substrate specificity. J Biol Chem 276: 38166-38172, 2001.
5. Cui X, Kawashima H, Barclay TB, Peters JM, Gonzalez FJ, Morgan ET, and Strobel HW. Molecular cloning and regulation of expression of two novel mouse CYP4F genes: Expression in peroxisome proliferator-activated receptor alpha-deficient mice upon lipopolysaccharide and clofibrate challenges. J Pharmacol Exp Ther 296: 542-550, 2001.
6. Escalante B, Erlij D, Falck JR, and McGiff JC. Effect of cytochrome P-450 arachidonate metabolites on ion-transport in rabbit kidney loop of Henle. Science 251: 799-802, 1991.
7. Henderson CJ, Bammler T, and Wolf CR. Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: Developmental and hormonal regulation in liver and kidney. Biochim Biophys Acta 1200: 182-190, 1994.
8. Heng YM, Kuo CS, Jones PS, Savory R, Schulz RM, Tomlinson SR, Gray TJ, and Bell DR. A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans. Biochem J 325: 741-749, 1997.
9. Hiratsuka M, Matsuura T, Watanabe E, Sato M, and Suzuki Y. Sex differences in constitutive level of renal lauric acid hydroxylase activities and CYP4A-related proteins in mice. Biol Pharm Bull 19: 512-517, 1996.
10. Holla VR, Adas F, Imig JD, Zhao X, Price E Jr, Olsen N, Kovacs WJ, Magnuson MA, Keeney DS, Breyer MD, Falck JR, Waterman MR, and Capdevila JH. Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension. Proc Natl Acad Sci USA 98: 5211-5216, 2001.
11. Honeck H, Gross V, Erdmann B, Kargel E, Neunaber R, Milia AF, Schneider W, Luft FC, and Schunck WH. Cytochrome P-450-dependent renal arachidonic acid metabolism in desoxycorticosterone acetate-salt hypertensive mice. Hypertension 36: 610-616, 2000.
12. Imig JD, Zou AP, Stec DE, Harder DR, Falck JR, and Roman RJ. Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles. Am J Physiol Regul Integr Comp Physiol 270: R217-R227, 1996.
13. Ito O, Alonso-Galicia M, Hopp KA, and Roman RJ. Localization of cytochrome P-450 4A isoforms along the rat nephron. Am J Physiol Renal Physiol 274: F395-F404, 1998.
14. Ito O, Omata K, Ito S, Hoagland KM, and Roman RJ. Effects of converting enzyme inhibitors on renal P-450 metabolism of arachidonic acid. Am J Physiol Regul Integr Comp Physiol 280: R822-R830, 2001.
15. Ito O and Roman RJ. Role of 20-HETE in elevating chloride transport in the thick ascending limb of Dahl SS/Jr rats. Hypertension 33: 419-423, 1999.
16. Lasker JM, Chen WB, Wolf I, Bloswick BP, Wilson PD, and Powell PK. Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney-role of CYP4F2 and CYP4A11. J Biol Chem 275: 4118-4126, 2000.
17. Nelson RD, Stricklett P, Gustafson C, Stevens A, Ausiello D, Brown D, and Kohan DE. Expression of an AQP2 Cre recombinase transgene in kidney and male reproductive system of transgenic mice. Am J Physiol Cell Physiol 275: C216-C226, 1998.
18. Nguyen X, Wang MH, Reddy KM, Falck JR, and Schwartzman ML. Kinetic profile of the rat CYP4A isoforms: Arachidonic acid metabolism and isoform-specific inhibitors. Am J Physiol Regul Integr Comp Physiol 276: R1691-R1700, 1999.
19. 1 by mass spectrometry. Biochem Pharmacol 62: 407-415, 2001.
20. Quigley R, Baum M, Reddy KM, Griener JC, and Falck JR. Effects of 20-HETE and 19(S)-HETE on rabbit proximal straight tubule volume transport. Am J Physiol Renal Physiol 278: F949-F953, 2000.
21. Schwartzman ML, da Silva JL, Lin F, Nishimura M, and Abraham NG. Cytochrome P-450 4A expression and arachidonic acid omega-hydroxylation in the kidney of the spontaneously hypertensive rat. Nephron 73: 652-663, 1996.
22. Schwartzman ML, Martasek P, Rios AR, Levere RD, Solangi K, Goodman AI, and Abraham NG. Cytochrome P-450-dependent arachidonic acid metabolism in human kidney. Kidney Int 37: 94-99, 1990.
23. Spiro RG. Studies on the renal glomerular basement membrane. J Biol Chem 242: 1915-1922, 1967.
24. Stec DE, Deng AY, Rapp JP, and Roman RJ. Cytochrome P-4504A genotype cosegregates with hypertension in Dahl S rats. Hypertension 27: 564-568, 1996.
25. Su P, Kaushal KM, and Kroetz DL. Inhibition of renal arachidonic acid omega-hydroxylase activity with ABT reduces blood pressure in the SHR. Am J Physiol Regul Integr Comp Physiol 275: R426-R438, 1998.
26. Terzi F, Burtin M, Hekmati M, Federici P, Grimber G, Briand P, and Friedlander G. Targeted expression of a dominant-negative EGF-R in the kidney reduces tubulo-interstitial lesions after renal injury. J Clin Invest 106: 225-234, 2000.
27. Van Ess PJ, Pedersen WA, Culmsee C, Mattson MP, and Blouin RA. Elevated hepatic and depressed renal cytochrome P-450 activity in the Tg2576 transgenic mouse model of Alzheimer's disease. J Neurochem 80: 571-578, 2002.
28. Vinay P, Gougoux A, and Lemieux G. Isolation of a pure suspension of rat proximal tubules. Am J Physiol Renal Fluid Electrolyte Physiol 241: F403-F411, 1981.
29. Wang MH, Zhang F, Marji J, Zand BA, Nasjletti A, and Laniado-Schwartzman M. CYP4A1 antisense oligonucleotide reduces mesenteric vascular reactivity and blood pressure in SHR. Am J Physiol Regul Integr Comp Physiol 280: R255-R261, 2001.
30. + channel in renal arterioles. Am J Physiol Regul Integr Comp Physiol 273: R228-R237, 1997.
31. Zou AP, Imig JD, Demontellano PRO, Sui ZH, Falck JR, and Roman RJ. Effect of P-450 ω-hydroxylase metabolites of arachidonic acid on tubuloglomerular feedback. Am J Physiol Renal Fluid Electrolyte Physiol 266: F934-F941, 1994.