De-orphanization of cytochrome P450 2R1: A microsomal vitamin D 25-hydroxylase

Journal of Biological Chemistry

Volumn 278, Issue 39, 2003, Pages 38084-38093

  Cheng, Jeffrey B ^a   Motola, Daniel L ^a,b   Mangelsdorf, David J ^a,b   Russell, David W ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHY; ENZYMES; HYDROXYLATION; IMMUNOLOGY; RNA; TISSUE;

MITOCHONDRIAL ACTIVITIES;

VITAMINS;

CALCIFEDIOL; COLECALCIFEROL; COLECALCIFEROL HYDROXYLASE; CYTOCHROME P450 27A1; CYTOCHROME P450 2R1; CYTOCHROME P450 ISOENZYME; ERGOCALCIFEROL; LIGAND; MESSENGER RNA; MICROSOME ENZYME; MITOCHONDRIAL ENZYME; OXIDOREDUCTASE; SECOSTEROID; STEROL 27 HYDROXYLASE; UNCLASSIFIED DRUG; VITAMIN D; VITAMIN D RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; DNA LIBRARY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME DEFICIENCY; GENETIC CONSERVATION; HUMAN; HUMAN CELL; HYDROXYLATION; KIDNEY; LIGAND BINDING; LIVER; MICROSOME; MITOCHONDRION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; TESTIS; THIN LAYER CHROMATOGRAPHY; TRANSCRIPTION INITIATION; VITAMIN D METABOLISM;

25-HYDROXYVITAMIN D3 1-ALPHA-HYDROXYLASE; AMINO ACID SEQUENCE; ANIMALS; CYTOCHROME P-450 CYP27A1; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; MICE; MICROSOMES; MOLECULAR SEQUENCE DATA; RNA, MESSENGER; STEROID HYDROXYLASES;

ANIMALIA;

EID: 0141732321     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M307028200     Document Type: Article

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