The traditional Chinese herbal remedy tian xian activates pregnane X receptor and induces CYP3A gene expression in hepatocytes

Drug Metabolism and Disposition

Volumn 36, Issue 8, 2008, Pages 1538-1545

  Lichti Kaiser, Kristin ^a   Staudinger, Jeff L ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

16ALPHA CYANOPREGNENOLONE; ANTINEOPLASTIC AGENT; CYTOCHROME P450 3A; CYTOCHROME P450 3A11; CYTOCHROME P450 3A4; NON PRESCRIPTION DRUG; PREGNANE X RECEPTOR; RIFAMPICIN; TIAN XIAN WAN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER THERAPY; CHINESE MEDICINE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG CROSS REACTIVITY; DRUG ELIMINATION; DRUG MARKETING; DRUG RECEPTOR BINDING; DRUG SAFETY; DRUG UPTAKE; GENE EXPRESSION REGULATION; HERB DRUG INTERACTION; LIVER CELL; LIVER METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECEPTOR UPREGULATION; REPORTER GENE; TREATMENT CONTRAINDICATION;

ANIMALS; CELLS, CULTURED; CYTOCHROME P-450 CYP3A; DRUGS, CHINESE HERBAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEPATOCYTES; MICE; MICE, KNOCKOUT; RECEPTORS, STEROID;

MUS; RODENTIA;

EID: 47949083957     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.108.021774     Document Type: Article

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