Role of peroxisome proliferator-activated receptor-α (PPARα) in bezafibrate-induced hepatocarcinogenesis and cholestasis

Carcinogenesis

Volumn 26, Issue 1, 2005, Pages 219-227

  Hays, Thomas ^a   Rusyn, Ivan ^b   Burns, Amanda M ^a   Kennett, Mary J ^a   Ward, Jerrold M ^c   Gonzalez, Frank J ^d   Peters, Jeffrey M ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c SOBRAN INC   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEZAFIBRATE; BILE SALT; CARRIER PROTEIN; CHOLESTEROL 7ALPHA MONOOXYGENASE; CYCLINE; CYTOCHROME P450; FARNESOID X RECEPTOR; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; UNCLASSIFIED DRUG;

ADENOMA; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA REPAIR; DRUG CARCINOGENICITY; DRUG DNA INTERACTION; GENETIC CODE; INTRAHEPATIC CHOLESTASIS; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; NULL ALLELE; PRECANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT STRAIN; WILD TYPE;

ACYL-COA OXIDASE; ALKANE 1-MONOOXYGENASE; ANIMALS; BEZAFIBRATE; BILE ACIDS AND SALTS; BLOTTING, NORTHERN; CELL CYCLE PROTEINS; CHOLESTASIS; DISEASE MODELS, ANIMAL; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; LIVER NEOPLASMS; MALE; MICE; PEROXISOME PROLIFERATORS; PPAR ALPHA; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; TRANSCRIPTION FACTORS;

EID: 13444311098     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh285     Document Type: Article

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