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Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 6, 2001, Pages 3375-3380

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids

(8) Xie, Wen b Radominska Pandya, Anna c Shi, Yanhong b Simon, Cynthia M b Nelson, Michael C b Ong, Erwin S b Waxman, David J d Evans, Ronald M a,b

a HOWARD HUGHES MEDICAL INSTITUTE (United States)

b SALK INSTITUTE FOR BIOLOGICAL STUDIES (United States)

c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES (United States)

d USA (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CELL NUCLEUS RECEPTOR; LITHOCHOLIC ACID; LIVER PROTECTIVE AGENT; PROTEIN PXR; PROTEIN SXR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DETOXIFICATION; HYDROXYLATION; KNOCKOUT MOUSE; LIVER METABOLISM; LIVER PROTECTION; LIVER TOXICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BILE ACIDS AND SALTS; CELL LINE; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; CHOLESTASIS; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; HUMANS; LITHOCHOLIC ACID; MICE; MICE, KNOCKOUT; OXIDOREDUCTASES, N-DEMETHYLATING; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; SUBSTRATE SPECIFICITY;

ANIMALIA; RODENTIA;

EID: 0035853057 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.051014398 Document Type: Article

Times cited : (711)

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