Retinoids induce cytochrome P450 3A4 through RXR/VDR-mediated pathway

Biochemical Pharmacology

Volumn 75, Issue 11, 2008, Pages 2204-2213

  Wang, Kun ^a   Chen, Shiyong ^a   Xie, Wen ^b   Wan, Yu Jui Yvonne ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

CYP3A4; Retinoid; RXR; VDR

Indexed keywords

13 RETINAL; 13 RETINOL; 9 RETINAL; ALITRETINOIN; CALCITRIOL; CYTOCHROME P450 3A11; CYTOCHROME P450 3A4; HETERODIMER; HOMODIMER; ISOTRETINOIN; MESSENGER RNA; RETINOIC ACID; RETINOID DERIVATIVE; RETINOID X RECEPTOR; RETINOID X RECEPTOR ALPHA; RETINOL ACETATE; VITAMIN D RECEPTOR;

ARTICLE; CELL STRAIN CACO 2; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG SCREENING; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE, TUMOR; CHOLECALCIFEROL; CYTOCHROME P-450 CYP3A; ENZYME INDUCTION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MALE; MICE; RECEPTORS, CALCITRIOL; RETINOID X RECEPTOR ALPHA; RETINOIDS; TRETINOIN;

EID: 43049128132     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.02.030     Document Type: Article

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