Cytochrome P450-dependent renal arachidonic acid metabolism in desoxycorticosterone acetate-salt hypertensive mice

Hypertension

Volumn 36, Issue 4, 2000, Pages 610-616

  Honeck, Horst ^a   Gross, Volkmar ^a   Erdmann, Bettina ^a   Kärgel, Eva ^a   Neunaber, Ralf ^a   Milia, Anna Franca ^a   Schneider, Wolfgang ^a   Luft, Friedrich C ^a,b   Schunck, Wolf Hagen ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b FRANZ VOLHARD CLINIC   (Germany)

Author keywords

Arachidonic acid; Cytochrome P450; Hydroxyeicosatetraenoic acids; Kidney; Mice

Indexed keywords

ARACHIDONIC ACID; BEZAFIBRATE; CYTOCHROME P450; DEOXYCORTICOSTERONE ACETATE; HYDROXYICOSATETRAENOIC ACID; MEVINOLIN;

ANIMAL MODEL; ARACHIDONIC ACID METABOLISM; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ASSAY; ENZYME LOCALIZATION; HYPERTENSION; KIDNEY MICROSOME; MALE; MOUSE; NATRIURESIS; NONHUMAN; PRIORITY JOURNAL; VASCULAR SMOOTH MUSCLE;

EID: 0033779317     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.36.4.610     Document Type: Article

References (37)

1. P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
2. The role of eicosanoids in angiotensin-dependent hypertension
3. Cytochrome P450, the arachidonic acid cascade, and hypertension: New vistas for an old enzyme system
4. 20-HETE and the kidney: Resolution of old problems and new beginnings
5. Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue
6. The role of the cytochrome P450-dependent metabolites of arachidonic acid in blood pressure regulation and renal function: A review
7. Treatment with tin prevents the development of hypertension in spontaneously hypertensive rats
8. Isolation of preferentially expressed genes in the kidneys of hypertensive rats
9. Renal cytochrome P-450-arachidonic acid metabolism: Localization and hormonal regulation in SHR
10. Inhibition of renal arachidonic acid w-hydroxylase activity with ABT reduces blood pressure in the SHR
11. Endothelin-1 and CYP450 arachidonate metabolites interact to promote tissue injury in DOCA-salt hypertension
12. Effects of lipid-lowering agents in the Dahl salt-sensitive rat
13. Renal P450 metabolites of arachidonic acid and the development of hypertension in Dahl salt-sensitive rats
14. Cortical and medullary hemodynamics in deoxycorticosterone acetate-salt hypertensive mice
15. Chronic effects of lovastatin and bezafibrate on cortical and medullary hemodynamics in deoxy-corticosterone acetate-salt hypertensive mice
16. Hepatic microsomal enzyme induction, beta-oxidation, and cell proliferation following administration of clofibrate, gemfibrozil, or bezafibrate in the CD rat
17. 2 receptor
18. Cytochrome P-450 arachidonic acid epoxygenase
19. Arachidonic acid metabolism in rabbit renal cortex: Formation of two novel dihydroxyeicosatrienoic acids
20. Pentylenetetrazol seizures increase pronerve growth factor-like immunoreactivity in the reticular thalamic nucleus and nerve growth factor mRNA in the dentate gyrus
21. Species-specific induction of cytochrome P-4504A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs
22. Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: Developmental and hormonal regulation in liver and kidney
23. A novel murine P-450 gene, Cyp4al4, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans
24. CYP4A subfamily: Functional analysis by immunohisto-chemistry and in situ hybridization
25. Cytochrome P450 4A expression and arachidonic acid omega-hydroxylation in the kidney of the spontaneously hypertensive rat
26. Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles
27. Localization of cytochrome P450 4A isoforms along the rat nephron
28. Regulation of P-450 4A activity in the glomerulus of the rat
29. Lovastatin reduces renal vascular reactivity in spontaneously hypertensive rats
30. Clofibrate prevents the development of hypertension in Dahl salt-sensitive rats
31. + channel in renal arterioles
32. Renal oxygenases: Differential contribution to vasoconstriction induced by ET-1 and ANG II
33. Regulation of Na-K-ATPase activity in the proximal tubule: Role of the protein kinase C pathway and of eicosanoids
34. +)-2C1- cotransport via 20-HETE and PKC in medullary thick ascending limb
35. - absorption via a cytochrome P-450-dependent pathway in MTAL
36. Cyclooxygenase dependency of the renovascular actions of cytochrome P450-derived arachidonate metabolites
37. Human pulmonary arteries dilate to 20-HETE, an endogenous eicosanoid of lung tissue