Characterization of the oxidative metabolites of 17β-estradiol and estrone formed by 15 selectively expressed human cytochrome P450 isoforms

Endocrinology

Volumn 144, Issue 8, 2003, Pages 3382-3398

  Lee, Anthony J ^a   Cai, May Xiaoxin ^b   Thomas, Paul E ^b   Conney, Allan H ^b   Zhu, Bao Ting ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15ALPHA HYDROXYESTRONE; 16ALPHA HYDROXYESTROGEN; 16BETA HYDROXYESTROGEN; 2 HYDROXYESTRADIOL; 2 HYDROXYESTRONE; 4 HYDROXYESTRADIOL; 4 HYDROXYESTRONE; 7ALPHA HYDROXYESTRONE; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C18; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; CYTOCHROME P450 3A7; CYTOCHROME P450 4A11; ESTRADIOL; ESTROGEN; ESTROGEN DERIVATIVE; ESTRONE; ESTRONE DERIVATIVE; ISOENZYME; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHROMATOGRAPHY; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SUBSTRATE; ESTROGEN METABOLISM; GENE ACTIVITY; GENE EXPRESSION; HUMAN; HYDROXYLATION; OXIDATION; PRIORITY JOURNAL;

ARYL HYDROCARBON HYDROXYLASES; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; ESTRADIOL; ESTRONE; GENE EXPRESSION; HUMANS; HYDROXYLATION; ISOENZYMES; NADP; OXIDATION-REDUCTION; SUBSTRATE SPECIFICITY; TRANSFECTION;

EID: 0042315387     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-0192     Document Type: Article

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