Role of LXRs in control of lipogenesis

Genes and Development

Volumn 14, Issue 22, 2000, Pages 2831-2838

  Schultz, Joshua R ^a   Tu, Hua ^a   Luk, Alvin ^a   Repa, Joyce J ^b   Medina, Julio C ^a   Li, Leping ^a   Schwendner, Susan ^a   Wang, Shelley ^a   Thoolen, Martin ^a   Mangelsdorf, David J ^b   Lustig, Kevin D ^a   Shan, Bei ^a  

^a AMGEN INC   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Fatty acid; Lipogenesis; LXR; SREBP; Triglyceride

Indexed keywords

BENZENESULFONAMIDE DERIVATIVE; CELL NUCLEUS RECEPTOR; HORMONE RECEPTOR; LIVER X RECEPTOR; LIVER X RECEPTOR AGONIST; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; N METHYL N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; OXYSTEROL; PHOSPHOLIPID; STEROL; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; T 0314407; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DRUG IDENTIFICATION; FATTY ACID SYNTHESIS; GENE EXPRESSION; GENE TARGETING; HAMSTER; HUMAN; HUMAN CELL; LIPOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR GENE; REGULATORY MECHANISM;

ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; CRICETINAE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS; HYPERTRIGLYCERIDEMIA; LIPIDS; LIPOPROTEINS; LIVER; MICE; MICE, MUTANT STRAINS; PHOSPHOLIPIDS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SULFONAMIDES; TRANSCRIPTION FACTORS; TRIGLYCERIDES;

ANIMALIA; CRICETINAE; TRIFLUORO;

EID: 0034669171     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.850400     Document Type: Article

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