Expression and function of cytochrome P450 in brain drug metabolism

Current Drug Metabolism

Volumn 8, Issue 4, 2007, Pages 297-306

  Meyer, Ralf P ^a   Gehlhaus, M ^a   Knoth, R ^a   Volk, B ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Blood brain barrier; Brain; Cytochrome P450; Drug metabolism; Heme; Hippocampus; Neurological disease; Steroid hormone

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTENEDIONE; ANTICONVULSIVE AGENT; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE DERIVATIVE; CARBAMAZEPINE; CENTRAL NERVOUS SYSTEM AGENTS; CLOZAPINE; CYTOCHROME P450; DIAZEPAM; ESTRADIOL; FATTY ACID; GLUCOCORTICOID; HALOPERIDOL; HEME; HYDANTOIN; IMIPRAMINE; LAMOTRIGINE; NEUROLEPTIC AGENT; NICOTINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PRASTERONE; PROGESTERONE; STEROID; TESTOSTERONE; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; XENOBIOTIC AGENT;

ASTROCYTE; BLOOD BRAIN BARRIER; BLOOD FLOW; BRAIN NERVE CELL; CARCINOGENESIS; CELL TYPE; CEREBROSPINAL FLUID; CORPUS STRIATUM; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME LOCALIZATION; GLIA CELL; HIPPOCAMPUS; HUMAN; HYPOTHALAMUS; LIVER; MENTAL DISEASE; NEUROLOGIC DISEASE; NEUROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVIEW; SEIZURE; SEXUAL DYSFUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; ANTICONVULSANTS; BLOOD-BRAIN BARRIER; BRAIN; CENTRAL NERVOUS SYSTEM AGENTS; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GONADAL HORMONES; HEME; HIPPOCAMPUS; HUMANS; LIVER; NEUROGLIA; NEURONS; PROTEIN ISOFORMS; RECEPTORS, ANDROGEN; SIGNAL TRANSDUCTION;

EID: 34249009984     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920007780655478     Document Type: Review

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