메뉴 건너뛰기




Volumn 13, Issue 8, 1999, Pages 893-901

Paracrine glucocorticoid activity produced by mouse thymic epithelial cells

Author keywords

Cytochrome P450; Paracrine signaling; Reporter cells; Steroid biosynthesis; Thymocyte development

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; CHOLESTEROL; CORTICOSTERONE; CYTOCHROME P450; GLUCOCORTICOID; METYRAPONE; MIFEPRISTONE; TRILOSTANE;

EID: 0032896835     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.13.8.893     Document Type: Article
Times cited : (109)

References (49)
  • 1
    • 0028151819 scopus 로고
    • Negative selection of lymphocytes
    • Nossal, G. J. (1994) Negative selection of lymphocytes. Cell 76, 229-239
    • (1994) Cell , vol.76 , pp. 229-239
    • Nossal, G.J.1
  • 2
    • 0031891488 scopus 로고    scopus 로고
    • Induction of and rescue from programmed cell death
    • von Boehmer, H., Sarukhan, A., and Buer, J. (1997) Induction of and rescue from programmed cell death. Immunologist 5, 185-191
    • (1997) Immunologist , vol.5 , pp. 185-191
    • Von Boehmer, H.1    Sarukhan, A.2    Buer, J.3
  • 3
    • 0028054017 scopus 로고
    • T-cell apoptosis detected in situ during positive, and negative selection in the thymus
    • Surh, C. D., and Sprent, J. (1994) T-cell apoptosis detected in situ during positive, and negative selection in the thymus. Nature (London) 372, 100-103
    • (1994) Nature (London) , vol.372 , pp. 100-103
    • Surh, C.D.1    Sprent, J.2
  • 4
    • 0030806085 scopus 로고    scopus 로고
    • In thymic selection, peptide diversity gives and takes away
    • Bevan, M. J. (1997) In thymic selection, peptide diversity gives and takes away. Immunity 7, 175-178
    • (1997) Immunity , vol.7 , pp. 175-178
    • Bevan, M.J.1
  • 6
    • 13244267182 scopus 로고
    • It is easier for a camel to pass the needle's eye
    • Janeway, C., Rudensky, A., Rath, S., and Murphy, D. (1992) It is easier for a camel to pass the needle's eye. Curr. Biol. 2, 26-28
    • (1992) Curr. Biol. , vol.2 , pp. 26-28
    • Janeway, C.1    Rudensky, A.2    Rath, S.3    Murphy, D.4
  • 7
    • 0029082346 scopus 로고
    • Thymic selection and cell division
    • Ernst, B., Surh, C. D., and Sprent, J. (1995) Thymic selection and cell division. J. Exp. Med. 182, 961-971
    • (1995) J. Exp. Med. , vol.182 , pp. 961-971
    • Ernst, B.1    Surh, C.D.2    Sprent, J.3
  • 8
    • 0029947045 scopus 로고    scopus 로고
    • Bone marrow-derived cells fail to induce positive selection in thymus reaggregation cultures
    • Ernst, B. B., Surh, C. D., and Sprent, J. (1996) Bone marrow-derived cells fail to induce positive selection in thymus reaggregation cultures. J. Exp. Med. 183, 1235-1240
    • (1996) J. Exp. Med. , vol.183 , pp. 1235-1240
    • Ernst, B.B.1    Surh, C.D.2    Sprent, J.3
  • 10
    • 0031011063 scopus 로고    scopus 로고
    • Thymus-derived glucocorticoids regulate antigen-specific positive selection
    • Vacchio, M. S., and Ashwell, J. D. (1997) Thymus-derived glucocorticoids regulate antigen-specific positive selection. J. Exp. Med. 185, 2033-2038
    • (1997) J. Exp. Med. , vol.185 , pp. 2033-2038
    • Vacchio, M.S.1    Ashwell, J.D.2
  • 11
    • 0028933798 scopus 로고
    • Neuroendocrine-immune system interactions, and autoimmunity
    • 1995
    • Wilder, R. L. (1995) Neuroendocrine-immune system interactions, and autoimmunity. Annu. Rev. Immunol. 13, 307-338, (1995)
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 307-338
    • Wilder, R.L.1
  • 12
    • 0029665099 scopus 로고    scopus 로고
    • b-restricted peptide-induced thymic apoptosis by glucocorticoid receptor antagonist RU486 in T cell receptor transgenic mice
    • b-restricted peptide-induced thymic apoptosis by glucocorticoid receptor antagonist RU486 in T cell receptor transgenic mice. Eur. J. Immunol. 26, 428-434
    • (1996) Eur. J. Immunol. , vol.26 , pp. 428-434
    • Xue, Y.1    Murdjeva, M.2    Okret, S.3    McConkey, D.4    Kiuossis, D.5    Jondal, M.6
  • 14
    • 0027238610 scopus 로고
    • Killing of immature CD4+ CD8+ thymocytes in vivo by anti-CD3 or 5'-(N-ethyl)-carboxamide adenosine is blocked by glucocorticoid receptor antagonist RU-486
    • published erratum appears in Eur. J. Immunol. (1993) Oct.; 23: 2734
    • Jondal, M., Okret, S., and McConkey, D. (1993) Killing of immature CD4+ CD8+ thymocytes in vivo by anti-CD3 or 5'-(N-ethyl)-carboxamide adenosine is blocked by glucocorticoid receptor antagonist RU-486 [published erratum appears in Eur. J. Immunol. (1993) Oct.; 23: 2734]. Eur. J. Immunol. 23, 1246-1250
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1246-1250
    • Jondal, M.1    Okret, S.2    McConkey, D.3
  • 15
    • 0027513268 scopus 로고
    • Apoptosis
    • Cohen, J. J. (1993) Apoptosis. Immunol. Today 14, 126-30
    • (1993) Immunol. Today , vol.14 , pp. 126-130
    • Cohen, J.J.1
  • 17
    • 0028233225 scopus 로고
    • Steroid production in the thymus: Implications for thymocyte selection
    • Vacchio, M. S., Papadopoulos, V., and Ashwell, J. D. (1994) Steroid production in the thymus: implications for thymocyte selection. J. Exp. Med. 179, 1835-1846
    • (1994) J. Exp. Med. , vol.179 , pp. 1835-1846
    • Vacchio, M.S.1    Papadopoulos, V.2    Ashwell, J.D.3
  • 18
    • 0029123504 scopus 로고
    • Disruption of hypothalamic-pituitary-adrenocortical system in transgenic mice expressing type II glucocorticoid receptor antisense ribonucleic acid permanently impairs T cell function: Effects on T cell trafficking, and T cell responsiveness during postnatal development
    • Morale, M. C., Batticane, N., Gallo, F., Barden, N., and Marchetti, B. (1995) Disruption of hypothalamic-pituitary-adrenocortical system in transgenic mice expressing type II glucocorticoid receptor antisense ribonucleic acid permanently impairs T cell function: effects on T cell trafficking, and T cell responsiveness during postnatal development. Endocrinology 136, 3949-3960
    • (1995) Endocrinology , vol.136 , pp. 3949-3960
    • Morale, M.C.1    Batticane, N.2    Gallo, F.3    Barden, N.4    Marchetti, B.5
  • 19
    • 0000697658 scopus 로고
    • The adrenal cortex
    • (Feilig, P., Baxter, J. D., and Frohman, L., eds) McGraw-Hill, New York
    • Miller, W. L., and Tyrrell, J. B. (1995) The adrenal cortex. In Endocrinology and Metabolism, 3rd Ed (Feilig, P., Baxter, J. D., and Frohman, L., eds) pp. 555-711, McGraw-Hill, New York
    • (1995) Endocrinology and Metabolism, 3rd Ed , pp. 555-711
    • Miller, W.L.1    Tyrrell, J.B.2
  • 20
    • 0031309124 scopus 로고    scopus 로고
    • Neurosteroids: A role in aging? New functions in the central, and peripheral nervous systems
    • Baulieu, E. E. (1997)Neurosteroids: a role in aging? New functions in the central, and peripheral nervous systems. Aging 9, 12
    • (1997) Aging , vol.9 , pp. 12
    • Baulieu, E.E.1
  • 21
    • 0030036766 scopus 로고    scopus 로고
    • Development and regeneration of the nervous system: A role for neurosteroids
    • Schumacher, M., Robel, P., and Baulieu, E. E. (1996) Development and regeneration of the nervous system: a role for neurosteroids. Dev. Neurosci. 18, 6-21
    • (1996) Dev. Neurosci. , vol.18 , pp. 6-21
    • Schumacher, M.1    Robel, P.2    Baulieu, E.E.3
  • 23
    • 0028989525 scopus 로고
    • A key enzyme in the biosynthesis of neurosteroids, 3β-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase (3β-HSD), is expressed in rat brain
    • Guennoun, R., Fiddes, R. J., Gouezou, M., Lombes, M., and Baulieu, E. E. (1995) A key enzyme in the biosynthesis of neurosteroids, 3β-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase (3β-HSD), is expressed in rat brain. Brain Res. Mol. Brain Res. 30, 287-300
    • (1995) Brain Res. Mol. Brain Res. , vol.30 , pp. 287-300
    • Guennoun, R.1    Fiddes, R.J.2    Gouezou, M.3    Lombes, M.4    Baulieu, E.E.5
  • 24
    • 0028818993 scopus 로고
    • Messenger RNAs encoding steroidogenic enzymes are expressed in rodent brain
    • Stromstedt, M., and Waterman, M. R. (1995) Messenger RNAs encoding steroidogenic enzymes are expressed in rodent brain. Brain Res. Mol. Brain Res. 34, 75-88
    • (1995) Brain Res. Mol. Brain Res. , vol.34 , pp. 75-88
    • Stromstedt, M.1    Waterman, M.R.2
  • 27
    • 0031045545 scopus 로고    scopus 로고
    • Metabolism of 27-,25-, and 24-hydroxycholesterol in rat glial cells, and neurons
    • Zhang, J., Akwa, Y., el-Etr, M., Baulieu, E. E., and Sjovall, J. (1997)Metabolism of 27-,25-, and 24-hydroxycholesterol in rat glial cells, and neurons. Biochem. J. 322, 175-184
    • (1997) Biochem. J. , vol.322 , pp. 175-184
    • Zhang, J.1    Akwa, Y.2    El-Etr, M.3    Baulieu, E.E.4    Sjovall, J.5
  • 28
    • 0029618368 scopus 로고
    • Steroid hormone receptors: Many actors in search of a plot
    • Beato, M., Herrlich, P., and Schutz, G. (1995) Steroid hormone receptors: many actors in search of a plot. Cell 83, 851-857
    • (1995) Cell , vol.83 , pp. 851-857
    • Beato, M.1    Herrlich, P.2    Schutz, G.3
  • 29
    • 0030026713 scopus 로고    scopus 로고
    • Molecular determinants of glucocorticoid receptor function, and tissue sensitivity to glucocorticoids
    • Bamberger, C. M., Schulte, H. M., and Chrousos, G. P. (1996) Molecular determinants of glucocorticoid receptor function, and tissue sensitivity to glucocorticoids. Endocr. Rev. 17, 245-261
    • (1996) Endocr. Rev. , vol.17 , pp. 245-261
    • Bamberger, C.M.1    Schulte, H.M.2    Chrousos, G.P.3
  • 30
    • 0030824266 scopus 로고    scopus 로고
    • A new function for the C-terminal zinc finger of the glucocorticoid receptor. Repression of RelA transactivation
    • Liden, J., Delaunay, F., Rafter, I., Gustafsson, J.-A., and Okret, S. (1997) A new function for the C-terminal zinc finger of the glucocorticoid receptor. Repression of RelA transactivation. J. Biol. Chem. 272, 21467-21472
    • (1997) J. Biol. Chem. , vol.272 , pp. 21467-21472
    • Liden, J.1    Delaunay, F.2    Rafter, I.3    Gustafsson, J.-A.4    Okret, S.5
  • 32
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 33
    • 0019973310 scopus 로고
    • Fractionation of the rat ventral prostate with respect to isolation, and exocytosis of the prostatic secretion protein
    • Haaparanta, T., Pousette, A., Hogberg, B., Gustafsson, J. A., and Glaumann, H. (1982) Fractionation of the rat ventral prostate with respect to isolation, and exocytosis of the prostatic secretion protein. Biochim. Biophys. Acta 716, 79-93
    • (1982) Biochim. Biophys. Acta , vol.716 , pp. 79-93
    • Haaparanta, T.1    Pousette, A.2    Hogberg, B.3    Gustafsson, J.A.4    Glaumann, H.5
  • 34
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 35
    • 0026748962 scopus 로고
    • Zone-specific expression of aldosterone synthase cytochrome P-450, and cytochrome P-45011 beta in rat adrenal cortex: Histochemical basis for the functional zonation
    • Ogishima, T., Suzuki, H., Hata, J., Mitani, F., and Ishimura, Y. (1992) Zone-specific expression of aldosterone synthase cytochrome P-450, and cytochrome P-45011 beta in rat adrenal cortex: histochemical basis for the functional zonation. Endocrinology 130, 2971-2977
    • (1992) Endocrinology , vol.130 , pp. 2971-2977
    • Ogishima, T.1    Suzuki, H.2    Hata, J.3    Mitani, F.4    Ishimura, Y.5
  • 37
    • 0028838494 scopus 로고
    • Rhodamine 123: A useful probe for monitoring T cell activation
    • Ferlini, C., Biselli, R., Nisini, R., and Fattorossi, A. (1995) Rhodamine 123: a useful probe for monitoring T cell activation. Cytometry 21, 282-293
    • (1995) Cytometry , vol.21 , pp. 282-293
    • Ferlini, C.1    Biselli, R.2    Nisini, R.3    Fattorossi, A.4
  • 38
    • 0029895803 scopus 로고    scopus 로고
    • T cell receptor-independent apoptosis of thymocyte clones induced by a thymic epithelial cell line is mediated by steroids
    • Zilberman, Y., Yefenof, E., Oron, E., Dorogin, A., and Guy, R. (1996) T cell receptor-independent apoptosis of thymocyte clones induced by a thymic epithelial cell line is mediated by steroids. Cell. Immunol. 170, 78-84
    • (1996) Cell. Immunol. , vol.170 , pp. 78-84
    • Zilberman, Y.1    Yefenof, E.2    Oron, E.3    Dorogin, A.4    Guy, R.5
  • 39
    • 0027058389 scopus 로고
    • Development of fetal thymocytes in organ culture: Effect of corticosteroids
    • Skinner, M. A., Moffatt, L., and Skinner, S. J. (1992) Development of fetal thymocytes in organ culture: effect of corticosteroids. Int. J. Dev. Biol. 36, 573-577
    • (1992) Int. J. Dev. Biol. , vol.36 , pp. 573-577
    • Skinner, M.A.1    Moffatt, L.2    Skinner, S.J.3
  • 40
    • 0028806218 scopus 로고
    • A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis, and alters thymocyte development
    • King, L. B., Vacchio, M. S., Dixon, K., Hunziker, R., Margulies, D. H., and Ashwell, J. D. (1995) A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis, and alters thymocyte development. Immunity 3, 647-656
    • (1995) Immunity , vol.3 , pp. 647-656
    • King, L.B.1    Vacchio, M.S.2    Dixon, K.3    Hunziker, R.4    Margulies, D.H.5    Ashwell, J.D.6
  • 41
    • 0025831964 scopus 로고
    • Excessive cycling converts PCR products to random-length higher molecular weight fragments
    • Bell, D. A., and DeMarini, D. M. (1991) Excessive cycling converts PCR products to random-length higher molecular weight fragments. Nucleic Acids Res. 19, 5079
    • (1991) Nucleic Acids Res. , vol.19 , pp. 5079
    • Bell, D.A.1    DeMarini, D.M.2
  • 42
    • 0032539807 scopus 로고    scopus 로고
    • Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells
    • Cascio, C., Prasad, V. V. K., Lin, Y. Y., Lieberman, S., and Papadopoulos, V. (1998) Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells. Proc. Natl. Acad. Sci. U. S. A. 95, 2862-2867
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 2862-2867
    • Cascio, C.1    Prasad, V.V.K.2    Lin, Y.Y.3    Lieberman, S.4    Papadopoulos, V.5
  • 44
    • 0027220012 scopus 로고
    • Latent agonist activity of the steroid antagonist, RU486, is unmasked in cells treated with activators of protein kinase A
    • Nordeen, S. K., Bona, B. J., and Moyer, M. L. (1993) Latent agonist activity of the steroid antagonist, RU486, is unmasked in cells treated with activators of protein kinase A. Mol. Endocrinol. 7, 731-742
    • (1993) Mol. Endocrinol. , vol.7 , pp. 731-742
    • Nordeen, S.K.1    Bona, B.J.2    Moyer, M.L.3
  • 45
    • 0029847788 scopus 로고    scopus 로고
    • Induction of apoptosis and p53 expression in immature thymocytes by direct interaction with thymic epithelial cells
    • Schreiber, L., Sharabi, Y., Schwartz, D., Goldfinger, N., Brodie, C., Rotter, V., and Shoham, J. (1996) Induction of apoptosis and p53 expression in immature thymocytes by direct interaction with thymic epithelial cells. Scand. J. Immunol. 44, 314-322
    • (1996) Scand. J. Immunol. , vol.44 , pp. 314-322
    • Schreiber, L.1    Sharabi, Y.2    Schwartz, D.3    Goldfinger, N.4    Brodie, C.5    Rotter, V.6    Shoham, J.7
  • 47
    • 0030602798 scopus 로고    scopus 로고
    • The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte
    • Crompton, T., Gilmour, K. C., and Owen, M. J. (1996) The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte. Cell 86, 243-251
    • (1996) Cell , vol.86 , pp. 243-251
    • Crompton, T.1    Gilmour, K.C.2    Owen, M.J.3
  • 48
    • 0002049245 scopus 로고
    • The immune system
    • Blalock, J. E. (1994) The immune system. Immunologist 2, 8-15
    • (1994) Immunologist , vol.2 , pp. 8-15
    • Blalock, J.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.