Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel

Journal of Clinical Investigation

Volumn 116, Issue 6, 2006, Pages 1696-1702

  Nakagawa, Kiyoshi ^a   Holla, Vijaykumar R ^a   Wei, Yuan ^b   Wang, Wen Hui ^b   Gatica, Arnaldo ^a   Wei, Shouzou ^a   Mei, Shaojun ^a   Miller, Crystal M ^a   Dae, Ryong Cha ^a   Price Jr , Edward ^a   Zent, Roy ^a,c   Pozzi, Ambra ^a   Breyer, Matthew D ^a   Guan, Youfei ^a   Falck, John R ^d   Waterman, Michael R ^a   Capdevila, Jorge H ^a,e  

^a VANDERBILT UNIVERSITY   (United States)

^b NEW YORK MEDICAL COLLEGE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMILORIDE; ARACHIDONIC ACID; CYTOCHROME P450 4A; CYTOCHROME P450 4A10; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; CHANNEL GATING; CONTROLLED STUDY; EARLY DIAGNOSIS; FEMALE; GENETIC DISORDER; HYPERTENSION; KIDNEY DYSFUNCTION; KIDNEY EPITHELIUM; KIDNEY TUBULE ABSORPTION; MALE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; NORMOTENSIVE HYDROCEPHALUS; PATIENT CARE; PHYSIOLOGY; PRIORITY JOURNAL; SALT INTAKE;

AMILORIDE; ANIMALS; ARACHIDONIC ACIDS; BLOOD PRESSURE; CYTOCHROME P-450 ENZYME SYSTEM; ELECTROPHYSIOLOGY; EPITHELIAL SODIUM CHANNEL; FEMALE; HUMANS; HYPERTENSION; KIDNEY; MALE; MICE; MICE, KNOCKOUT; PYRIMIDINES; SODIUM; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; SODIUM, DIETARY;

EID: 33745197144     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI27546     Document Type: Article

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