Functional expression of human cytochrome P450 enzymes in Escherichia coli

Current Drug Metabolism

Volumn 7, Issue 4, 2006, Pages 411-429

  Yun, Chul Ho ^a   Yim, Sung Kun ^a   Kim, Dong Hyun ^a   Ahn, Taeho ^a  

^a Chonnam National University   (South Korea)

Author keywords

Cytochrome P450; Escherichia coli; Heterologous expression; Molecular chaperone; NADPH P450 oxidoreductase; Temperature effect

Indexed keywords

AMINO ACID; AMPICILLIN; CARCINOGEN; CHAPERONE; CHLORAMPHENICOL; CYTOCHROME P450; CYTOCHROME P450 17; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; CYTOCHROME P450 3A7; DRUG METABOLIZING ENZYME; ERYTHROMYCIN; KANAMYCIN; PUROMYCIN; RECOMBINANT ENZYME; STREPTOMYCIN; TETRACYCLINE; TOXIC SUBSTANCE; UNINDEXED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; BACTERIAL CELL; BACTERIUM CULTURE; CATALYSIS; DRUG MECHANISM; DRUG METABOLISM; DRUG OXIDATION; ENZYME ISOLATION; ENZYME STABILITY; ESCHERICHIA COLI; GENE EXPRESSION SYSTEM; HETEROLOGOUS EXPRESSION; HUMAN; LOW TEMPERATURE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN MODIFICATION; REVIEW; TEMPERATURE SENSITIVITY;

CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; ESCHERICHIA COLI; GENE EXPRESSION; HUMANS; RECOMBINANT PROTEINS;

EID: 33646494635     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920006776873472     Document Type: Review

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