Alternative Splicing Determines the Function of CYP4F3 by Switching Substrate Specificity

Journal of Biological Chemistry

Volumn 276, Issue 41, 2001, Pages 38166-38172

  Christmas, Peter ^a   Jones, Jeffrey P ^c   Patten, Christopher J ^e   Rock, Dan A ^c   Zheng, Yimin ^d   Cheng, Shing Ming ^a   Weber, Brittany M ^a   Carlesso, Nadia ^b   Scadden, David T ^b   Rettie, Allan E ^d   Soberman, Roy J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c WASHINGTON STATE UNIVERSITY   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e Gentest Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BLOOD; GENES; SUBSTRATES;

FUNCTIONAL DIVERSITY;

PIGMENTS;

ARACHIDONIC ACID; CYTOCHROME P450; CYTOCHROME P450 4F3; CYTOCHROME P450 4F3A; CYTOCHROME P450 4F3B; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN KINASE C; UNCLASSIFIED DRUG; ISOENZYME; LEUKOTRIENE B4 20 HYDROXYLASE; LEUKOTRIENE B4 20-HYDROXYLASE; MESSENGER RNA; MIXED FUNCTION OXIDASE; PRIMER DNA;

ALTERNATIVE RNA SPLICING; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME KINETICS; ENZYME LOCALIZATION; ENZYME SPECIFICITY; EXON; GASTROINTESTINAL TRACT; GENE EXPRESSION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HYDROXYLATION; KIDNEY; LIVER; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN INTERACTION; SEQUENCE HOMOLOGY; START CODON; TRACHEA; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; LIVER MICROSOME; METABOLISM; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALTERNATIVE SPLICING; BASE SEQUENCE; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; HUMANS; ISOENZYMES; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; PROTEIN CONFORMATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUBSTRATE SPECIFICITY;

EID: 0035851164     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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