Fatty acid hydroperoxides support cytochrome P450 2S1-mediated bioactivation of benzo[a]pyrene-7,8-dihydrodiol

Molecular Pharmacology

Volumn 76, Issue 5, 2009, Pages 1044-1052

  Bui, Peter H ^a,b,c   Hsu, Erin L ^a,b,c   Hankinson, Oliver ^a,b,c  

^a UCLA Molecular Toxicology Interdepartmental Program   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7,8 DIHYDRO 7,8 DIHYDROXYBENZO[A]PYRENE; CUMENE HYDROPEROXIDE; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 2S1; CYTOCHROME P450 3A4; FREE RADICAL; GUAIACOL; HYDROPEROXIDE DERIVATIVE; HYDROPEROXY EICOSATETRAENOIC ACID; HYDROPEROXY OCTADECADIENOIC ACID; OXIDIZING AGENT; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; CYTOTOXICITY; EPOXIDATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; KINETICS; MAMMAL CELL; PRIORITY JOURNAL; WESTERN BLOTTING;

ANIMALS; BIOTRANSFORMATION; CELL LINE, TUMOR; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; DIHYDROXYDIHYDROBENZOPYRENES; ENVIRONMENTAL POLLUTANTS; HUMANS; LIPID PEROXIDES; MICE; OXIDATION-REDUCTION;

EID: 70350455899     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.109.057760     Document Type: Article

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