-
1
-
-
0028584429
-
Bile acid synthesis from cholesterol: Regulatory and auxiliary pathways
-
Javitt, N. B. 1994. Bile acid synthesis from cholesterol: regulatory and auxiliary pathways. FASEB J. 8: 1308-1311.
-
(1994)
FASEB J
, vol.8
, pp. 1308-1311
-
-
Javitt, N.B.1
-
2
-
-
0000778664
-
Regulation of bile acid synthesis
-
Chiang, J. Y. L. 1998. Regulation of bile acid synthesis. Front. Biosci. 3: D176-193.
-
(1998)
Front. Biosci.
, vol.3
-
-
Chiang, J.Y.L.1
-
3
-
-
0027414207
-
Formation of 7α- And 7β-hydroxylated bile acid precursors from 27-hydroxycholesterol in human liver microsomes and mitochondria
-
Shoda, J., A. Toll, M. Axelson, F. Pieper, K. Wikvall, and J. Sjovall. 1993. Formation of 7α- and 7β-hydroxylated bile acid precursors from 27-hydroxycholesterol in human liver microsomes and mitochondria. Hepatology. 17: 395-403.
-
(1993)
Hepatology
, vol.17
, pp. 395-403
-
-
Shoda, J.1
Toll, A.2
Axelson, M.3
Pieper, F.4
Wikvall, K.5
Sjovall, J.6
-
4
-
-
0026738208
-
7α-hydroxylation of 27-hydroxycholesterol in human liver microsomes
-
Bjorkhem, I., B. Nyberg, and K. Einarsson. 1992. 7α-hydroxylation of 27-hydroxycholesterol in human liver microsomes. Biochim. Biophys. Acta. 1128: 73-76.
-
(1992)
Biochim. Biophys. Acta.
, vol.1128
, pp. 73-76
-
-
Bjorkhem, I.1
Nyberg, B.2
Einarsson, K.3
-
5
-
-
0026594957
-
Cholesterol is converted to 7α-hydroxy-3-oxo-4-cholestenoic acid in liver mitochondria. Evidence for a mitochondrial sterol 7α-hydroxylase
-
Axelson, M., J. Shoda, J. Sjovall, A. Toll, and K. Wikvall. 1992. Cholesterol is converted to 7α-hydroxy-3-oxo-4-cholestenoic acid in liver mitochondria. Evidence for a mitochondrial sterol 7α-hydroxylase. J. Biol. Chem. 267: 1701-1704.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 1701-1704
-
-
Axelson, M.1
Shoda, J.2
Sjovall, J.3
Toll, A.4
Wikvall, K.5
-
6
-
-
0027523427
-
Cholesterol and 27-hydroxycholesterol 7α-hydroxylation: Evidence for two different enzymes
-
Martin, K. O., K. Budai, and N. B. Javitt. 1993. Cholesterol and 27-hydroxycholesterol 7α-hydroxylation: evidence for two different enzymes. J. Lipid Res. 34: 581-588.
-
(1993)
J. Lipid Res.
, vol.34
, pp. 581-588
-
-
Martin, K.O.1
Budai, K.2
Javitt, N.B.3
-
7
-
-
0026500434
-
7α-Hydroxylation of 26-hydroxycholesterol, 3β-hydroxy-5-cholestenoic acid and 3β-hydroxy-5-cholenoic acid by cytochrome P-450 in pig liver microsomes
-
Toll, A., J. Shoda, M. Axelson, J. Sjovall, and K. Wikvall. 1992.7α-Hydroxylation of 26-hydroxycholesterol, 3β-hydroxy-5-cholestenoic acid and 3β-hydroxy-5-cholenoic acid by cytochrome P-450 in pig liver microsomes. FEBS Lett. 296: 73-76.
-
(1992)
FEBS Lett
, vol.296
, pp. 73-76
-
-
Toll, A.1
Shoda, J.2
Axelson, M.3
Sjovall, J.4
Wikvall, K.5
-
8
-
-
0028989206
-
7α-Hydroxylation of 25-hydroxycholesterol and 27-hydroxycholesterol in human fibroblasts
-
Zhang, J., O. Larsson, and J. Sjovall. 1995. 7α-Hydroxylation of 25-hydroxycholesterol and 27-hydroxycholesterol in human fibroblasts. Biochim. Biophys. Acta. 1256: 353-359.
-
(1995)
Biochim. Biophys. Acta.
, vol.1256
, pp. 353-359
-
-
Zhang, J.1
Larsson, O.2
Sjovall, J.3
-
9
-
-
0029143894
-
7α-Hydroxylation of 27-hydroxycholesterol in rat brain microsomes
-
Zhang, J., Y. Akwa, E. E. Baulieu, and J. Sjovall. 1995. 7α-Hydroxylation of 27-hydroxycholesterol in rat brain microsomes. C. R. Acad. Sci. Ser. III, Sci. Vie. 318: 345-349.
-
(1995)
C. R. Acad. Sci. Ser. III, Sci. Vie.
, vol.318
, pp. 345-349
-
-
Zhang, J.1
Akwa, Y.2
Baulieu, E.E.3
Sjovall, J.4
-
10
-
-
0029589217
-
A novel cytochrome P450 expressed primarily in brain
-
Stapleton, G., M. Steel, M. Richardson, J. O. Mason, K. A. Rose, R. G. M. Morris, and R. Lathe. 1995. A novel cytochrome P450 expressed primarily in brain. J. Biol. Chem. 270: 29739-29745.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 29739-29745
-
-
Stapleton, G.1
Steel, M.2
Richardson, M.3
Mason, J.O.4
Rose, K.A.5
Morris, R.G.M.6
Lathe, R.7
-
11
-
-
0030610365
-
7α-Hydroxylation of 27-hydroxycholesterol: Biologic role in the regulation of cholesterol synthesis
-
Martin, K. O., A. B. Reiss, R. Lathe, and N. B. Javitt. 1997. 7α-Hydroxylation of 27-hydroxycholesterol: biologic role in the regulation of cholesterol synthesis. J. Lipid Res. 38: 1053-1058.
-
(1997)
J. Lipid Res.
, vol.38
, pp. 1053-1058
-
-
Martin, K.O.1
Reiss, A.B.2
Lathe, R.3
Javitt, N.B.4
-
12
-
-
12644253822
-
Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7α-hydroxy dehydroepiandrosterone and 7α-hydroxypregnenolone
-
Rose, K. A., G. Stapleton, K. Dott, M. P. Kieny, R. Best, M. Schwarz, D. W. Russell, I. Bjorkhem, J. Seckl, and R. Lathe. 1997. Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7α-hydroxy dehydroepiandrosterone and 7α-hydroxypregnenolone. Proc. Natl. Acad. Sci. USA. 94: 4925-4930.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4925-4930
-
-
Rose, K.A.1
Stapleton, G.2
Dott, K.3
Kieny, M.P.4
Best, R.5
Schwarz, M.6
Russell, D.W.7
Bjorkhem, I.8
Seckl, J.9
Lathe, R.10
-
13
-
-
0028068796
-
Atherosclerosis and sterol 27-hydroxylase: Evidence for a role of this enzyme in elimination of cholesterol from human macrophages
-
Bjorkhem, I., O. Andersson, U. Diczfalusy, B. Sevastik, R-j. Xiu, C. Duan, and E. Lund. 1994. Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages. Proc. Natl. Acad. Sci. USA. 91: 8592-8596.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8592-8596
-
-
Bjorkhem, I.1
Andersson, O.2
Diczfalusy, U.3
Sevastik, B.4
Xiu, R.-J.5
Duan, C.6
Lund, E.7
-
14
-
-
0029666290
-
Disruption of cholesterol 7α-hydroxylase gene in mice: II. Bile acid deficiency is overcome by induction of oxysterol 7α-hydroxylase
-
Schwarz, M., E. G. Lund, K. D. R. Setchell, H. J. Kayden, J. E. Zerwekh, I. Bjorkhem, J. Hertz, and D. W. Russell. 1996. Disruption of cholesterol 7α-hydroxylase gene in mice: II. Bile acid deficiency is overcome by induction of oxysterol 7α-hydroxylase. J. Biol. Chem. 271: 18024-18031.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 18024-18031
-
-
Schwarz, M.1
Lund, E.G.2
Setchell, K.D.R.3
Kayden, H.J.4
Zerwekh, J.E.5
Bjorkhem, I.6
Hertz, J.7
Russell, D.W.8
-
15
-
-
0031595674
-
Cholesterol 7α-hydroxylase knockout mouse: A model for monohydroxy bile acid-related neonatal cholestasis
-
Arnon, R., T. Yoshimura, A. Reiss, K. Budai, J. H. Lefkowitch, and N. B. Javitt. 1998. Cholesterol 7α-hydroxylase knockout mouse: a model for monohydroxy bile acid-related neonatal cholestasis. Gastroenterology. 115: 1223-1228.
-
(1998)
Gastroenterology
, vol.115
, pp. 1223-1228
-
-
Arnon, R.1
Yoshimura, T.2
Reiss, A.3
Budai, K.4
Lefkowitch, J.H.5
Javitt, N.B.6
-
16
-
-
0000107790
-
Neonatal cholestasis: Identification of a metabolic error in bile acid synthesis
-
Abstract #627
-
Javitt, N. B., A. Kok, and M. Gut. 1984. Neonatal cholestasis: identification of a metabolic error in bile acid synthesis. Pediatr. Res. 18: Abstract #627.
-
(1984)
Pediatr. Res.
, pp. 18
-
-
Javitt, N.B.1
Kok, A.2
Gut, M.3
-
17
-
-
0028868818
-
Hormonal regulation of the cholesterol 7α-hydroxylase gene (CYP7)
-
Crestani, M., D. Stroup, and J. Y. L. Chiang. 1995. Hormonal regulation of the cholesterol 7α-hydroxylase gene (CYP7). J. Lipid Res. 36: 2419-2432.
-
(1995)
J. Lipid Res.
, vol.36
, pp. 2419-2432
-
-
Crestani, M.1
Stroup, D.2
Chiang, J.Y.L.3
-
18
-
-
0026755177
-
Polymorphisms of human cholesterol 7α-hydroxylase
-
Karam, W. G., and J. Y. L. Chiang. 1992. Polymorphisms of human cholesterol 7α-hydroxylase. Biochem. Biophys. Res. Commun. 185: 588-595.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.185
, pp. 588-595
-
-
Karam, W.G.1
Chiang, J.Y.L.2
-
19
-
-
0032211865
-
Identification of a new inborn error in bile acid synthesis: Mutation of the oxysterol 7α-hydroxylase gene causes severe neonatal liver disease
-
Setchell, K. D. R., M. Schwarz, N. C. O'Connell, E. G. Lund, D. L. Davis, R. Lathe, H. R. Thompson, R. Weslie Tyson, R. J. Sokol, and D. W. Russell. 1998. Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7α-hydroxylase gene causes severe neonatal liver disease. J. Clin. Invest. 102: 1690-1703.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 1690-1703
-
-
Setchell, K.D.R.1
Schwarz, M.2
O'Connell, N.C.3
Lund, E.G.4
Davis, D.L.5
Lathe, R.6
Thompson, H.R.7
Weslie Tyson, R.8
Sokol, R.J.9
Russell, D.W.10
-
20
-
-
0027998460
-
Distribution profiles of GC content around the translation initiation site in different species
-
Mizuno, M., and M. Kanehisa. 1994. Distribution profiles of GC content around the translation initiation site in different species. FEBS Lett. 352: 7-10.
-
(1994)
FEBS Lett
, vol.352
, pp. 7-10
-
-
Mizuno, M.1
Kanehisa, M.2
-
21
-
-
0030845921
-
Identification and characterization of a mouse oxysterol 7α-hydroxylase cDNA
-
Schwarz, M., E. G. Lund, R. Lathe, I. Bjorkhem, and D. W. Russell. 1997. Identification and characterization of a mouse oxysterol 7α-hydroxylase cDNA. J. Biol. Chem. 272: 23995-24001.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23995-24001
-
-
Schwarz, M.1
Lund, E.G.2
Lathe, R.3
Bjorkhem, I.4
Russell, D.W.5
-
22
-
-
0028971143
-
MatInd and MatInspector: New fast and versatile tools for detection of consensus matches in nucleotide sequence data
-
Quandt, K., K. Frech, H. Karas, E. Wingender, and T. Werner. 1995. MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 23: 4878-4884.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 4878-4884
-
-
Quandt, K.1
Frech, K.2
Karas, H.3
Wingender, E.4
Werner, T.5
-
23
-
-
0028225462
-
SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
-
Wang, X., R. Sato, M. S. Brown, X. Hua, and J. L. Goldstein. 1994. SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell. 77: 53-62.
-
(1994)
Cell
, vol.77
, pp. 53-62
-
-
Wang, X.1
Sato, R.2
Brown, M.S.3
Hua, X.4
Goldstein, J.L.5
-
24
-
-
0025871394
-
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A
-
Flanagan, W. M., B. Corthesy, R. J. Bram, and G. R. Crabtree. 1991. Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. Nature. 352: 803-807.
-
(1991)
Nature
, vol.352
, pp. 803-807
-
-
Flanagan, W.M.1
Corthesy, B.2
Bram, R.J.3
Crabtree, G.R.4
-
25
-
-
0024475227
-
NF-KB: A pleiotropic mediator of inducible and tissue-specific gene control
-
Lenardo, M. J., and D. Baltimore. 1989. NF-KB: a pleiotropic mediator of inducible and tissue-specific gene control. Cell. 58: 227-229.
-
(1989)
Cell
, vol.58
, pp. 227-229
-
-
Lenardo, M.J.1
Baltimore, D.2
-
26
-
-
0027500843
-
The two zinc fingerlike domains of GATA-1 have different DNA binding specificities
-
Whyatt, D. J., E. deBoer, and F. Grosveld. 1993. The two zinc fingerlike domains of GATA-1 have different DNA binding specificities. EMBO J. 12: 4993-5005.
-
(1993)
EMBO J
, vol.12
, pp. 4993-5005
-
-
Whyatt, D.J.1
DeBoer, E.2
Grosveld, F.3
-
27
-
-
0025811870
-
The different tissue transcription patterns of genes for HNF1, C/EBP, HNF3, and HNF4 protein factors that govern liver-specific transcription
-
Xanthopoulos, K. G., V. R. Prezioso, W. S. Chen, F. M. Sladek, R. Cortese, and J. E. Darnell. 1991. The different tissue transcription patterns of genes for HNF1, C/EBP, HNF3, and HNF4 protein factors that govern liver-specific transcription. Proc. Natl. Acad. Sci. USA. 88: 3807-3811.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 3807-3811
-
-
Xanthopoulos, K.G.1
Prezioso, V.R.2
Chen, W.S.3
Sladek, F.M.4
Cortese, R.5
Darnell, J.E.6
-
28
-
-
0022650157
-
Purification of nuclear factor 1 by DNA recognition site affinity chromatography
-
Rosenfeld, P. J., and T. J. Kelly. 1986. Purification of nuclear factor 1 by DNA recognition site affinity chromatography. J. Biol. Chem. 261: 1398-1408.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 1398-1408
-
-
Rosenfeld, P.J.1
Kelly, T.J.2
-
29
-
-
0026088436
-
The expression of a catalytically active cholesterol 7a-hydroxylase cytochrome P450 in E. coli
-
Li, Y. C., and J. Y. L. Chiang. 1991. The expression of a catalytically active cholesterol 7a-hydroxylase cytochrome P450 in E. coli. J. Biol. Chem. 266: 19186-19191.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 19186-19191
-
-
Li, Y.C.1
Chiang, J.Y.L.2
-
30
-
-
0027446505
-
The P450 superfamily: Update on new sequences, gene mapping, accession number, early trivial names of enzymes, and nomenclature
-
Nelson, D. R., T. Kamataki, D. J. Waxman, F. P. Guengerich, R. W. Estabrook, R. Feyereisen, F. J. Gonzalez, M. J. Coon, I. C. Gunsalus, O. Gotoh, K. Okuda, and D. W. Nebert. 1993. The P450 superfamily: update on new sequences, gene mapping, accession number, early trivial names of enzymes, and nomenclature. DNA Cell Biol. 12: 1-51.
-
(1993)
DNA Cell Biol
, vol.12
, pp. 1-51
-
-
Nelson, D.R.1
Kamataki, T.2
Waxman, D.J.3
Guengerich, F.P.4
Estabrook, R.W.5
Feyereisen, R.6
Gonzalez, F.J.7
Coon, M.J.8
Gunsalus, I.C.9
Gotoh, O.10
Okuda, K.11
Nebert, D.W.12
-
31
-
-
0032559475
-
Biochemical characterization of the 7α-hydroxylase activities towards 27-hydroxycholesterol and dehydroepiandrosterone in pig liver
-
Norlin, M., and K. Wikvall. 1998. Biochemical characterization of the 7α-hydroxylase activities towards 27-hydroxycholesterol and dehydroepiandrosterone in pig liver. Biochem. Biophys. Acta. 1390: 269-281.
-
(1998)
Biochem. Biophys. Acta.
, vol.1390
, pp. 269-281
-
-
Norlin, M.1
Wikvall, K.2
-
32
-
-
0032890337
-
Oxysterols and atherosclerosis
-
Brown, A. J., and W. Jessup. 1999. Oxysterols and atherosclerosis. Atherosclerosis. 142: 1-28.
-
(1999)
Atherosclerosis
, vol.142
, pp. 1-28
-
-
Brown, A.J.1
Jessup, W.2
-
33
-
-
0025120211
-
Regulation of the mevalonate pathway
-
Goldstein, J. L., and M. S. Brown. 1990. Regulation of the mevalonate pathway. Nature. 343: 425-430.
-
(1990)
Nature
, vol.343
, pp. 425-430
-
-
Goldstein, J.L.1
Brown, M.S.2
-
34
-
-
0029805887
-
An oxysterol signaling pathway mediated by the nuclear receptor LXRα
-
D
-
Janowski, B. A., P. J. Willy, T. R. Devi, J. R. Falck, D. and J. Mangelsdorf. 1996. An oxysterol signaling pathway mediated by the nuclear receptor LXRα. Nature. 383: 728-731.
-
(1996)
Nature
, vol.383
, pp. 728-731
-
-
Janowski, B.A.1
Willy, P.J.2
Devi, T.R.3
Falck, J.R.4
Mangelsdorf, J.5
-
35
-
-
0032515989
-
Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids
-
Baulieu, E. E., and P. Robel. 1998. Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids. Proc. Natl. Acad. Sci. USA. 95: 4089-4091.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4089-4091
-
-
Baulieu, E.E.1
Robel, P.2
-
36
-
-
0032516063
-
Dehydroepiandrosterone: A potential signaling molecule for neocortical organization during development
-
Compagnone, N. A., and S. H. Mellon. 1998. Dehydroepiandrosterone: a potential signaling molecule for neocortical organization during development. Proc. Natl. Acad. Sci. USA. 95: 4678-4683.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4678-4683
-
-
Compagnone, N.A.1
Mellon, S.H.2
-
37
-
-
0029549843
-
Dehydroepiandrosterone (DHEA) is a neuroactive neurosteroid
-
Robel, P., and E. E. Baulieu. 1995. Dehydroepiandrosterone (DHEA) is a neuroactive neurosteroid. Ann. NY Acad. Sci. 774: 82-110.
-
(1995)
Ann. NY Acad. Sci.
, vol.774
, pp. 82-110
-
-
Robel, P.1
Baulieu, E.E.2
-
38
-
-
0033026760
-
Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
-
Wang, H., J. Chen, K. Hollister, L. C. Sowers, and B. M. Forman. 1999. Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. Mol. Cell. 3: 543-553.
-
(1999)
Mol. Cell.
, vol.3
, pp. 543-553
-
-
Wang, H.1
Chen, J.2
Hollister, K.3
Sowers, L.C.4
Forman, B.M.5
-
39
-
-
0033591297
-
Identification of a nuclear receptor for bile acids
-
Makishima, M., A. Y. Okamoto, J. J. Repa, H. Tu, R. M. Learned, A. Luk, M. V. Hull, K. D. Lustig, D. J. Mangelsdorf, and B. Shan. 1999. Identification of a nuclear receptor for bile acids. Science. 284: 1362-1365.
-
(1999)
Science
, vol.284
, pp. 1362-1365
-
-
Makishima, M.1
Okamoto, A.Y.2
Repa, J.J.3
Tu, H.4
Learned, R.M.5
Luk, A.6
Hull, M.V.7
Lustig, K.D.8
Mangelsdorf, D.J.9
Shan, B.10
-
40
-
-
0033591387
-
Bile acids: Natural ligands for an orphan nuclear receptor
-
Parks, D. J., S. G. Blanchard, R. K. Bledsoe, G. Chandra, T. G. Consler, S. A. Kliewer, J. B. Stimmel, T. M. Willson, A. M. Zavacki, D. D. Moore, and J. M. Lehmann. 1999. Bile acids: Natural ligands for an orphan nuclear receptor. Science. 284: 1365-1368.
-
(1999)
Science
, vol.284
, pp. 1365-1368
-
-
Parks, D.J.1
Blanchard, S.G.2
Bledsoe, R.K.3
Chandra, G.4
Consler, T.G.5
Kliewer, S.A.6
Stimmel, J.B.7
Willson, T.M.8
Zavacki, A.M.9
Moore, D.D.10
Lehmann, J.M.11
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