Phenytoin induction of the Cyp2c37 gene is mediated by the constitutive androstane receptor

Drug Metabolism and Disposition

Volumn 34, Issue 12, 2006, Pages 2003-2010

  Jackson, Jonathan P ^a,b   Ferguson, Stephen S ^a,c   Negishi, Masahiko ^a   Goldstein, Joyce A ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c CellzDirect Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 PREGNEN 3BETA OL 20 ONE 16ALPHA CARBONITRILE; CONSTITUTIVE ANDROSTANE RECEPTOR; CORN OIL; CYTOCHROME P450 2C; CYTOCHROME P450 2C37; LUCIFERASE; PHENOBARBITAL; PHENYTOIN; PREGNANE X RECEPTOR; PREGNENOLONE; XENOBIOTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME BINDING; ENZYME INDUCTION; GENE CONTROL; GENE DELETION; GENE IDENTIFICATION; GENE INDUCTION; GENE LOCATION; GENE MUTATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; RNA TRANSLATION; TRANSACTIVATION;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIVER; MALE; MICE; MICE, INBRED C3H; MICE, KNOCKOUT; PHENOBARBITAL; PHENYTOIN; PREGNENOLONE CARBONITRILE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; RNA, MESSENGER; TRANSCRIPTION FACTORS;

MURINAE;

EID: 33751541421     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.106.012005     Document Type: Article

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