Structure and chromosomal assignment of the sterol 12α-hydroxylase gene (CYP8B1) in human and mouse: Eukaryotic cytochrome P-450 gene devoid of introns

Genomics

Volumn 56, Issue 2, 1999, Pages 184-196

  Gåfvels, Mats ^a   Olin, Maria ^a   Chowdhary, Bhanu P ^b   Raudsepp, Terje ^b   Andersson, Ulla ^a   Persson, Bengt ^a   Jansson, Monica ^a   Björkhem, Ingemar ^a   Eggertsen, Gösta ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 3P; GENE ASSIGNMENT; GENE LOCATION; HUMAN; MOLECULAR CLONING; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SOUTHERN BLOTTING; SPECIES DIFFERENCE;

EUKARYOTA; MAMMALIA; MURINAE; RODENTIA;

EID: 0033106423     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1998.5606     Document Type: Article

References (46)

1. Ahlberg J., Angelin B., Björkhem I., Gustafsson J.-Å., Rafter J. Effects of treatment with chenodeoxycholic acid on liver microsomal metabolism of steroids in man. J. Lab. Clin. Med. 95:1980;188-194.
2. Andersson U., Eggertsen G., Björkhem I. Rabbit liver contains one major sterol 12α-hydroxylase with broad substrate specificity. Biochim. Biophys. Acta. 1389:1997;150-154.
3. Ariga H., Imamura Y., Iguchi-Ariga S. M. DNA replication origin and transcriptional enhancer in c-myc gene share the c-myc protein binding sequences. EMBO J. 8:1989;4273-4279.
4. Björkhem I., Andersson U., Sudjana-Sugiaman E., Eggertsen G., Hylemon P. Studies on the link between HMG-CoA reductase and cholesterol 7α-hydroxylase in lymph-fistula rats: Evidence for both transcriptional mechanisms for down-regulation of the two enzymes by bile acids. J. Lipid Res. 34:1993;1497-1503.
5. Brunel F., Ochoa A., Schaeffer E., Boissier F., Guillou Y., Cereghini S., Cohen G. N., Zakin M. M. Interactions of DNA-binding proteins with the 5′ region of the human transferrin gene. J. Biol. Chem. 263:1988;10180-10185.
6. Chiang J. Y. L., Stroup D. Identification of a liver nuclear protein factor responsive to bile acid inhibition of cholesterol 7α-hydroxylase gene. J. Biol. Chem. 269:1994;17502-17507.
7. Chowdhary B. P., Thomsen P. D., Harbitz I., Landset M., Gustavsson I. Precise localization of the genes for glucose phosphate isomerase (GPI), calcium release channel (CRC), hormone-sensitive lipase (LIPE), and growth hormone (GH) in pigs, using nonradioactive in situ hybridization. Cytogenet. Cell Genet. 67:1994;211-214.
8. Cohen J. C., Cali J. J., Jelinek D. F., Mehrabian M., Sparkes R. S., Lusis A. J., Russell D. W., Hobbs H. H. Cloning of the human cholesterol 7 alpha-hydroxylase gene (CYP7) and localization to chromosome 8q11-q12. Genomics. 14:1992;153-161.
9. Eggertsen G., Olin M., Andersson U., Ishida H., Kubota S., Hellman U., Okuda K.-I., Björkhem I. Molecular cloning and expression of rabbit sterol 12α-hydroxylase. J. Biol. Chem. 271:1996;32269-32275.
10. Einarsson K., Åkerlund J.-E., Reihnér E., Björkhem I. 12α-hydroxylase activity in human liver and its relation to cholesterol 7α-hydroxylase activity. J. Lipid Res. 33:1992;1591-1595.
11. Gillies S. D., Morrison S. L., Oi V. T., Tonegawa S. A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene. Cell. 33:1983;717-728.
12. Grayson D. R., Costa R. H., Xanthopoulos K. G., Darnell J. E. One factor recognizes the liver-specific enhancers in alpha 1-antitrypsin and transthyretin genes. Science. 239:1988;786-788.
13. Guertin M., LaRue H., Bernier D., Wrange Ö, Chevrette M., Gingras M.-C., Belanger L. Enhancer and promoter elements directing activation and glucocorticoid repression of the alpha 1-fetoprotein gene in hepatocytes. Mol. Cell. Biol. 8:1988;1398-1407.
14. Herbert A. RNA editing, introns and evolution. Trends Genet. 12:1996;6-9.
15. Hurst L. D., McVean G., Moore T. Imprinted genes have few and small introns. Nat. Genet. 12:1996;234-237.
16. Ishida H., Noshiro M., Okuda K., Coon M. Purification and characterization of 7α-hydroxy-4-chlolesten-3-one 12α-hydroxylase. J. Biol. Chem. 267:1992;21319-21323.
17. Isshiki H., Akira S., Sugita T., Nishio Y., Hashimoto S., Pawlowski T., Suematsu S., Kishimoto T. Reciprocal expression of NF-IL6 and C/EBP in hepatocytes: Possible involvement of NF-IL6 in acute phase protein gene expression. New Biologist. 3:1991;63-70.
18. Korb M., Ke Y., Johnson L. F. Stimulation of gene expression by introns: Conversion of an inhibitory intron to a stimulatory intron by alteration of the splice donor sequence. Nucleic Acids Res. 21:1993;5901-5908.
19. Leitersdorf E., Reshef A., Meiner V., Levitzki R., Pressman Schwartz S., Dann E. J., Berkman N., Cali J. J., Klapholz L., Berginer V. M. Frameshift and splice-junction mutations in the sterol 27-hydroxylase gene cause cerebrotendinous xanthomatosis in Jews of Moroccan origin. J. Clin. Invest. 91:1993;2488-2496.
20. Lewis D. F. V. Cytochromes P450: Structure, Function and Mechanism. 1996;Taylor & Francis, London. p. 169-208.
21. Lichter P., Cremer T., Borden J., Manuelidis L., Ward D. C. Delineation of individual chromosomes in metaphase and interphase cells byin situ. Hum. Genet. 80:1988;224-234.
22. Lichter P., Tang C.-J., Call K., Hermanson G., Evans G. A., Housman D., Ward D. C. High resolution mapping of human chromosome 11 byin situ. Science. 247:1990;64-69.
23. Long M., Rosenberg C., Gilbert W. Intron phase correlations and the evolution of the intron/exon structure of genes. Proc. Natl. Acad. Sci. USA. 92:1995;12495-12499.
24. Mitelman F. An International System for Human Cytogenetic Nomenclature (ISCN). 1995;S. Karger, Basel.
25. Mullick J., Addaya S., Sucharov G., Avadhani N. G. Localization of a transcription promoter within the second exon of the cytochrome P-450c27/25 gene for the expression of the major species of two-kilobase mRNA. Biochemistry. 34:1995;13729-13742.
26. Nakajima N., Horikoshi M., Roeder R. G. Factors involved in specific transcription by mammalian RNA polymerase II: Purification, genetic specificity, and TATA box-promoter interactions of TFIID. Mol. Cell. Biol. 8:1988;4028-4040.
27. Nebert D., Nelson D. R., Adesnik M., Coon M. J., Estabrook R. W., Gonzalez F. J. The P450 superfamily: Updated listing of all genes and recommended nomenclature for the chromosomal loci. DNA. 8:1989;1-13.
28. Nesbitt M. N., Francke U. A system of nomenclature for band patterns of mouse chromosomes. Chromosoma. 41:1973;145-158.
29. Okuda K., Ogishima T., Noshiro M. Cholesterol 7α-hydroxylase and 12α-hydroxylase. Handbook of Experimental Pharmacology. 1992;Springer-Verlag, Berlin. p. 601-610.
30. Osborne T. Transcriptional control mechanisms in the regulation of cholesterol balance. Crit. Rev. Eukar. Gene Exp. 5:1995;317-335.
31. Persson B., Argos P. Prediction of transmembrane segments in proteins utilising multiple sequence alignments. J. Mol. Biol. 237:1994;182-192.
32. Pierce J. C., Sternberg N., Sauer B. A mouse genomic library in the bacteriophage P1 cloning system: Organization and characterization. Mamm. Genome. 3:1992;550-558.
33. Postel E. H., Berberich S. J., Flint S. J., Ferrone C. A. Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis. Science. 261:1993;478-480.
34. Rikitake Y., Moran E. DNA-binding properties of the E1A-associated 300-kilodalton protein. Mol. Cell. Biol.1. 2:1992;2826-2836.
35. Rost B., Casadio R., Fariselli P., Sander C. Transmembrane helices predicted at 95% accuracy. Protein Sci. 4:1995;521-533.
36. Saffer J. D., Jackson S. P., Annarella M. B. Developmental expression of Sp1 in the mouse. Mol. Cell. Biol. 11:1991;2189-2199.
37. Sambrook J., Fritsch E. F., Maniatis T. Molecular Cloning: A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
38. Stewart E. A., Cox D. Radiation hybrid mapping. Dear P. Genome Mapping: A Practical Approach. 1997;73-93 Oxford Univ. Press, Oxford.
39. Strachan T., Read A. P. Human Molecular Genetics. 1996;BIOS and Wiley-Liss, New York.
40. Tennyson C. N., Klamut H. L., Worton R. G. The human dystrophin gene requires 16 hours to be transcribed and is cotranscriptionally spliced. Nat. Genet. 9:1993;184-190.
41. Twisk J., Hoekman M. F. M., Lehman E. M., Meijer P., Mager W. H., Princen H. M. G. Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase gene transcription. Hepatology. 21:1997;501-510.
42. Whyatt D. J., deBoer E., Grosveld F. The two zinc finger-like domains of GATA-1 have different DNA binding specificities. EMBO J. 12:1993;4993-5005.
43. Xin J.-H., Cowie A., Lachance P., Hassell J. A. Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells. Genes Dev. 6:1992;481-496.
44. Yokoyama C., Yabuki T., Inoue H., Yoshinore T., Hara S., Hatae T., Nagata M., Takahashi E.-I., Tanabe T. Human gene encoding prostacyklin synthase (PTGIS): Genomic organization, chromosomal localization, and promoter activity. Genomics. 36:1996;296-304.
45. Yoshida Y., Noshiro M., Aoyama Y., Kawamoto T., Horiuchi T., Gotoh O. Structural and evolutionary studies on sterol 14-demetylase P450 (CYP51), the most conserved P450 monooxygenase. II. Evolutionary analysis of protein and gene structure. J. Biochem. 122:1997;1122-1128.
46. Zhou D.-X., Yen T. S. The ubiquitous transcription factor Oct-1 and the liver-specific factor HNF-1 are both required to activate transcription of a hepatitis B virus promoter. Mol. Cell. Biol. 11:1991;1353-1359.