Identification of a meander region proline residue critical for heme binding to cytochrome P450: Implications for the catalytic function of human CYP4B1

Biochemistry

Volumn 37, Issue 37, 1998, Pages 12847-12851

  Zheng, Yi Min ^a   Fisher, Michael B ^a   Yokotani, Noboru ^b   Fujii Kuriyama, Yoshiaki ^c   Rettie, Allan E ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; HEME; OXYGENASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARCINOGENESIS; CATALYSIS; CELL STRAIN HEPG2; HUMAN; HUMAN CELL; HYDROXYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BINDING SITES; CATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; HEME; HUMANS; HYDROXYLATION; INSECTS; LAURIC ACIDS; MUTAGENESIS, SITE-DIRECTED; PROLINE; RABBITS; RATS; SERINE; STEROID HYDROXYLASES; TESTOSTERONE;

EID: 0032530321     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi981280m     Document Type: Article

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