Effects of the differentiated keratinocyte phenotype on expression levels of CYP1-4 family genes in human skin cells

Toxicology and Applied Pharmacology

Volumn 213, Issue 2, 2006, Pages 135-144

  Du, Liping ^b   Neis, Mark M ^c   Ladd, Patricia A ^b   Lanza, Diane L ^d   Yost, Garold S ^d   Keeney, Diane S ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^d UNIVERSITY OF UTAH   (United States)

Author keywords

CYP; Cytochrome P450; Eicosanoids; Epidermis; Epithelial differentiation; Epoxygenase; Keratinocyte; Skin

Indexed keywords

ARACHIDONIC ACID; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 2B19; CYTOCHROME P450 2B6; CYTOCHROME P450 2C18; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 2J2; CYTOCHROME P450 2S9; CYTOCHROME P450 2W1; CYTOCHROME P450 3A4; CYTOCHROME P450 4B1; EPOXYICOSATRIENOIC ACID; LORICRIN; MESSENGER RNA; RNA 18S; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ARTICLE; BASAL CELL; CELL DIFFERENTIATION; CELL LEVEL; CELL STRUCTURE; CONTROLLED STUDY; EPIDERMIS CELL; GENE EXPRESSION; GRANULAR CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; MULTIGENE FAMILY; NEWBORN; PHENOTYPE; REAL TIME POLYMERASE CHAIN REACTION; SKIN CELL; UPREGULATION;

CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CYTOCHROME P-450 ENZYME SYSTEM; EICOSANOIDS; EPIDERMIS; HUMANS; ISOENZYMES; KERATINOCYTES; MALE; MIXED FUNCTION OXYGENASES; PHENOTYPE; RNA, MESSENGER; UP-REGULATION;

EID: 33646586642     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2005.10.003     Document Type: Article

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