Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-α-mediated downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase expression

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 21, Issue 11, 2001, Pages 1840-1845

  Post, Sabine M ^a   Duez, Hélène ^a   Gervois, Philippe P ^a   Staels, Bart ^a   Kuipers, Folkert ^a   Princen, Hans M G ^a  

^a TNO   (Netherlands)

Author keywords

Cholesterol excretion; Hepatocytes; PPAR null mice; Rats

Indexed keywords

BEZAFIBRATE; BILE ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; CIPROFIBRATE; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PIRINIXIC ACID; ROSIGLITAZONE; STEROL 27 HYDROXYLASE;

ANIMAL EXPERIMENT; ARTICLE; BILE ACID SYNTHESIS; BILE FLOW; CHOLESTEROL STONE; CONTROLLED STUDY; ENZYME REGULATION; ENZYME REPRESSION; FECES; LIPID COMPOSITION; LIPID METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION;

EID: 0035570381     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/hq1101.098228     Document Type: Article

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