CAR/PXR provides directives for Cyp3a41 gene regulation differently from Cyp3a11

Pharmacogenomics Journal

Volumn 4, Issue 2, 2004, Pages 91-101

  Anakk, S ^a   Kalsotra, A ^a   Kikuta, Y ^a   Huang, W ^b   Zhang, J ^b   Staudinger, J L ^c   Moore, D D ^b   Strobel, Henry W ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

CAR; Cytochrome P450 3As; Gender differences; PXR; Xenobiotic metabolism

Indexed keywords

1,4 BIS(3,5 DICHLORO 2 PYRIDYLOXY)BENZENE; 16ALPHA CYANOPREGNENOLONE; ANDROSTANE DERIVATIVE; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 3A; CYTOCHROME P450 3A11; CYTOCHROME P450 3A41; DEXAMETHASONE; ERYTHROMYCIN; ESTROGEN; ISOENZYME; MESSENGER RNA; N DEMETHYLASE; PHENOBARBITAL; PREGNANE X RECEPTOR; UNCLASSIFIED DRUG; XENOBIOTIC AGENT; CELL RECEPTOR; CYP3A11 PROTEIN, MOUSE; CYP3A41 PROTEIN, MOUSE; CYTOCHROME P450; MEMBRANE PROTEIN; OXIDOREDUCTASE; STEROID RECEPTOR; TRANSCRIPTION FACTOR; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CHROMOSOME 5; CONTROLLED STUDY; CORRELATION FUNCTION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INDUCTION; ENZYME REGULATION; ENZYME REPRESSION; ENZYME SPECIFICITY; EXON; FEMALE; GENE EXPRESSION; GENE LOCATION; GENETIC REGULATION; IMMUNOBLOTTING; KIDNEY; LIVER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; LIVER MICROSOME; MOUSE MUTANT; PHYSIOLOGY;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; ISOENZYMES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSOMES, LIVER; OXIDOREDUCTASES; OXIDOREDUCTASES, N-DEMETHYLATING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; TRANSCRIPTION FACTORS;

EID: 7044237266     PISSN: 1470269X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.tpj.6500222     Document Type: Article

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