Cytochrome P450 4F subfamily: At the crossroads of eicosanoid and drug metabolism

Pharmacology and Therapeutics

Volumn 112, Issue 3, 2006, Pages 589-611

  Kalsotra, Auinash ^a   Strobel, Henry W ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Cytochrome P450 4F; Cytokines; Drug metabolism; Gene regulation; Inflammation; Leukotriene B4

Indexed keywords

20 HYDROXYICOSATETRAENOIC ACID; ALPHA TOCOPHEROL; ANTIHISTAMINIC AGENT; BENZPHETAMINE; CAREBASTINE; CHLORPROMAZINE; CHLORPROMAZINE SULFOXIDE; CYTOCHROME P450; CYTOCHROME P450 4F; CYTOCHROME P450 4F1; CYTOCHROME P450 4F11; CYTOCHROME P450 4F12; CYTOCHROME P450 4F2; CYTOCHROME P450 4F3; CYTOCHROME P450 4F4; CYTOCHROME P450 4F5; CYTOCHROME P450 4F6; CYTOCHROME P450 4F8; CYTOKINE; EBASTINE; ETHYLMORPHINE; ICOSANOID; IMIPRAMINE; ISOENZYME; LEUKOTRIENE; NORCHLORPROMAZINE; OXYGENASE; PROSTAGLANDIN; PSYCHOTROPIC AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

BONE MARROW CELL; CELL ISOLATION; CYTOKINE PRODUCTION; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME SUBSTRATE; GENE EXPRESSION; GENE INDUCTION; GENETIC POLYMORPHISM; GENOME ANALYSIS; HUMAN; HYPERTENSION; ICOSANOID METABOLISM; INFLAMMATION; KIDNEY; LIVER CELL; LIVER TUMOR; MOUSE STRAIN; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NONHUMAN; PATHOPHYSIOLOGY; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; RAT STRAIN; REGULATORY MECHANISM; REVIEW; RNA SPLICING; RODENT; SEX DIFFERENCE; TISSUE SPECIFICITY; TRAUMATIC BRAIN INJURY;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; EICOSANOIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; KIDNEY; LEUKOTRIENES; LIVER; MICE; PHARMACEUTICAL PREPARATIONS; PROSTAGLANDINS; RATS;

EID: 33750000583     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2006.03.008     Document Type: Review

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