Expression of xenobiotic metabolizing enzymes in different lung compartments of smokers and nonsmokers

Environmental Health Perspectives

Volumn 114, Issue 11, 2006, Pages 1655-1661

  Thum, Thomas ^a,b   Erpenbeck, Veit J ^a   Moeller, Julia ^a   Hohlfeld, Jens M ^a   Krug, Norbert ^a   Borlak, Jürgen ^a  

^a FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Cytochrome P450 monooxygenases; Metabolism; Smoking; Transcription factors; Xenobiotic metabolizing enzymes

Indexed keywords

AROMATASE; CARCINOGEN; COTININE; CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; CYTOCHROME P450 2B6; CYTOCHROME P450 2C9; CYTOCHROME P450 3A5; DIMETHYLANILINE MONOOXYGENASE; DRUG METABOLIZING ENZYME; EPOXIDE HYDROLASE; GLUCOCORTICOID RECEPTOR; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE P1; ISOPROTEIN; LIVER X RECEPTOR; NICOTINE; TOBACCO SMOKE; TRANSCRIPTION FACTOR;

ADULT; ARTICLE; BRONCHUS BIOPSY; CLINICAL ARTICLE; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME METABOLISM; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG CANCER; LUNG LAVAGE; MALE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA ISOLATION; SMOKING; TREATMENT OUTCOME; XENOBIOTIC METABOLISM;

NICOTIANA TABACUM;

EID: 33750885465     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.8861     Document Type: Article

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