Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes

Journal of Biological Chemistry

Volumn 278, Issue 19, 2003, Pages 17277-17283

  Maglich, Jodi M ^b   Parks, Derek J ^b   Moore, Linda B ^b   Collins, Jon L ^b   Goodwin, Bryan ^b   Billin, Andrew N ^b   Stoltz, Catherine A ^b   Kliewer, Steven A ^b   Lambert, Millard H ^b   Willson, Timothy M ^b   Moore, John T ^a  

^a GLAXOSMITHKLINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST SELECTIVITY; FLUORESCENCE; PROTEINS;

CONSTITUTIVE ANDROSTANE RECEPTORS (CAR);

GENETIC ENGINEERING;

6 (4 CHLOROPHENYL)IMIDAZO[2,1 B][1,3]THIAZOLE 5 CARBALDEHYDE O (3,4 DICHLOROBENZYL)OXIME; ANDROGEN RECEPTOR; ANDROSTANE DERIVATIVE; ANDROSTANE RECEPTOR AGONIST; COMPLEMENTARY DNA; CYTOCHROME P450 2B6; HORMONE RECEPTOR STIMULATING AGENT; PHOSPHORUS 32; PREGNANE X RECEPTOR; RNA; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR; 6 (4 CHLOROPHENYL)IMIDAZO(2,1 B)(1,3)THIAZOLE 5 CARBALDEHYDE O (3,4 DICHLOROBENZYL)OXIME; 6-(4-CHLOROPHENYL)IMIDAZO(2,1-B)(1,3)THIAZOLE-5-CARBALDEHYDE O-(3,4-DICHLOROBENZYL)OXIME; CELL RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR; OXIME; THIAZOLE DERIVATIVE; TRANSCRIPTION FACTOR;

ARTICLE; ENERGY TRANSFER; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; LIVER CELL CULTURE; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; CELL CULTURE; DRUG EFFECT; DRUG POTENTIATION; GENETICS; LIVER CELL; METABOLISM; PHYSIOLOGY;

CELLS, CULTURED; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; OXIMES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; THIAZOLES; TRANSCRIPTION FACTORS;

EID: 0037931737     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300138200     Document Type: Article

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