-
1
-
-
78751560494
-
Pathogen recognition by the innate immune system
-
Kumar H, Kawai T, Akira S. Pathogen recognition by the innate immune system. Int Rev Immunol. 2011; 30 (1): 16-34.
-
(2011)
Int Rev Immunol.
, vol.30
, Issue.1
, pp. 16-34
-
-
Kumar, H.1
Kawai, T.2
Akira, S.3
-
2
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell. 2002; 10 (2): 417-26.
-
(2002)
Mol Cell.
, vol.10
, Issue.2
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
3
-
-
1642285783
-
NALP3 forms an IL-1βetaprocessing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, Tschopp J. NALP3 forms an IL-1βetaprocessing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity. 2004; 20 (3): 319-25.
-
(2004)
Immunity.
, vol.20
, Issue.3
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
4
-
-
0037312509
-
NALPs: A novel protein family involved in inflammation
-
Tschopp J, Martinon F, Burns K. NALPs: a novel protein family involved in inflammation. Nat Rev Mol Cell Biol. 2003; 4 (2): 95-104.
-
(2003)
Nat Rev Mol Cell Biol.
, vol.4
, Issue.2
, pp. 95-104
-
-
Tschopp, J.1
Martinon, F.2
Burns, K.3
-
6
-
-
80052164574
-
The inflammasome: An integrated view
-
Gross O, Thomas CJ, Guarda G, Tschopp J. The inflammasome: an integrated view. Immunol Rev. 2011; 243 (1): 136-51.
-
(2011)
Immunol Rev.
, vol.243
, Issue.1
, pp. 136-151
-
-
Gross, O.1
Thomas, C.J.2
Guarda, G.3
Tschopp, J.4
-
7
-
-
33847376042
-
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
-
Faustin B, Lartigue L, Bruey JM, Luciano F, Sergienko E, Bailly-Maitre B, Volkmann N, Hanein D, Rouiller I, Reed JC. Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation. Mol Cell. 2007; 25 (5): 713-24.
-
(2007)
Mol Cell.
, vol.25
, Issue.5
, pp. 713-724
-
-
Faustin, B.1
Lartigue, L.2
Bruey, J.M.3
Luciano, F.4
Sergienko, E.5
Bailly-Maitre, B.6
Volkmann, N.7
Hanein, D.8
Rouiller, I.9
Reed, J.C.10
-
8
-
-
34249941913
-
Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling
-
Duncan JA, Bergstralh DT, Wang Y, Willingham SB, Ye Z, Zimmermann AG, Ting JP. Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling. Proc Natl Acad Sci U S A. 2007; 104 (19): 8041-6.
-
(2007)
Proc Natl Acad Sci U S A.
, vol.104
, Issue.19
, pp. 8041-8046
-
-
Duncan, J.A.1
Bergstralh, D.T.2
Wang, Y.3
Willingham, S.B.4
Ye, Z.5
Zimmermann, A.G.6
Ting, J.P.7
-
10
-
-
84866512376
-
Cell volume regulation modulates NLRP3 inflammasome activation
-
Compan V, Baroja-Mazo A, Lopez-Castejon G, Gomez AI, Martinez CM, Angosto D, Montero MT, Herranz AS, Bazan E, Reimers D, Mulero V, Pelegrin P. Cell volume regulation modulates NLRP3 inflammasome activation. Immunity. 2012; 37 (3): 487-500.
-
(2012)
Immunity.
, vol.37
, Issue.3
, pp. 487-500
-
-
Compan, V.1
Baroja-Mazo, A.2
Lopez-Castejon, G.3
Gomez, A.I.4
Martinez, C.M.5
Angosto, D.6
Montero, M.T.7
Herranz, A.S.8
Bazan, E.9
Reimers, D.10
Mulero, V.11
Pelegrin, P.12
-
11
-
-
84866386287
-
Structural and functional analysis of the NLRP4 pyrin domain
-
Eibl C, Grigoriu S, Hessenberger M, Wenger J, Puehringer S, Pinheiro AS, Wagner RN, Proell M, Reed JC, Page R, Diederichs K, Peti W. Structural and functional analysis of the NLRP4 pyrin domain. Biochemistry. 2012; 51 (37): 7330-41.
-
(2012)
Biochemistry.
, vol.51
, Issue.37
, pp. 7330-7341
-
-
Eibl, C.1
Grigoriu, S.2
Hessenberger, M.3
Wenger, J.4
Puehringer, S.5
Pinheiro, A.S.6
Wagner, R.N.7
Proell, M.8
Reed, J.C.9
Page, R.10
Diederichs, K.11
Peti, W.12
-
12
-
-
0033607768
-
ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells
-
Masumoto J, Taniguchi S, Ayukawa K, Sarvotham H, Kishino T, Niikawa N, Hidaka E, Katsuyama T, Higuchi T, Sagara J. ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. J Biol Chem. 1999; 274 (48): 33835-8.
-
(1999)
J Biol Chem.
, vol.274
, Issue.48
, pp. 33835-33838
-
-
Masumoto, J.1
Taniguchi, S.2
Ayukawa, K.3
Sarvotham, H.4
Kishino, T.5
Niikawa, N.6
Hidaka, E.7
Katsuyama, T.8
Higuchi, T.9
Sagara, J.10
-
13
-
-
0037077283
-
The PYRIN-CARD protein ASC is an activating adaptor for caspase-1
-
Srinivasula SM, Poyet JL, Razmara M, Datta P, Zhang Z, Alnemri ES. The PYRIN-CARD protein ASC is an activating adaptor for caspase-1. J Biol Chem. 2002; 277 (24): 21119-22.
-
(2002)
J Biol Chem.
, vol.277
, Issue.24
, pp. 21119-21122
-
-
Srinivasula, S.M.1
Poyet, J.L.2
Razmara, M.3
Datta, P.4
Zhang, Z.5
Alnemri, E.S.6
-
14
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol. 2009; 27: 519-50.
-
(2009)
Annu Rev Immunol.
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
15
-
-
34548031870
-
The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
-
Fernandes-Alnemri T, Wu J, Yu JW, Datta P, Miller B, Jankowski W, Rosenberg S, Zhang J, Alnemri ES. The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ. 2007; 14 (9): 1590-604.
-
(2007)
Cell Death Differ.
, vol.14
, Issue.9
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.W.3
Datta, P.4
Miller, B.5
Jankowski, W.6
Rosenberg, S.7
Zhang, J.8
Alnemri, E.S.9
-
16
-
-
79952159132
-
Emerging inflammasome effector mechanisms
-
Lamkanfi M. Emerging inflammasome effector mechanisms. Nat Rev Immunol. 2011; 11 (3): 213-20.
-
(2011)
Nat Rev Immunol.
, vol.11
, Issue.3
, pp. 213-220
-
-
Lamkanfi, M.1
-
17
-
-
84875542536
-
Recognition of bacteria by inflammasomes
-
von Moltke J, Ayres JS, Kofoed EM, Chavarría-Smith J, Vance RE. Recognition of bacteria by inflammasomes. Annu Rev Immunol. 2013; 31: 73-106.
-
(2013)
Annu Rev Immunol.
, vol.31
, pp. 73-106
-
-
von Moltke, J.1
Ayres, J.S.2
Kofoed, E.M.3
Chavarría-Smith, J.4
Vance, R.E.5
-
18
-
-
84858677223
-
Sensing and reacting to microbes through the inflammasomes
-
Franchi L, Muñoz-Planillo R, Núñez G. Sensing and reacting to microbes through the inflammasomes. Nat Immunol. 2012; 13 (4): 325-32.
-
(2012)
Nat Immunol.
, vol.13
, Issue.4
, pp. 325-332
-
-
Franchi, L.1
Muñoz-Planillo, R.2
Núñez, G.3
-
19
-
-
84866307663
-
Inflammasomes and viruses: Cellular defence versus viral offence
-
Gram AM, Frenkel J, Ressing ME. Inflammasomes and viruses: cellular defence versus viral offence. J Gen Virol. 2012; 93 (Pt 10): 2063-75.
-
(2012)
J Gen Virol.
, vol.93
, Issue.PART 10
, pp. 2063-2075
-
-
Gram, A.M.1
Frenkel, J.2
Ressing, M.E.3
-
20
-
-
82955233705
-
Familial Mediterranean fever and related periodic fever syndromes/autoinflammatory diseases
-
Savic S, Dickie LJ, Battellino M, McDermott MF. Familial Mediterranean fever and related periodic fever syndromes/autoinflammatory diseases. Curr Opin Rheumatol. 2012; 24 (1): 103-12.
-
(2012)
Curr Opin Rheumatol.
, vol.24
, Issue.1
, pp. 103-112
-
-
Savic, S.1
Dickie, L.J.2
Battellino, M.3
McDermott, M.F.4
-
21
-
-
84856394478
-
Immunology in clinic review series; focus on autoinflammatory diseases: Role of inflammasomes in autoinflammatory syndromes
-
Ozkurede VU, Franchi L. Immunology in clinic review series; focus on autoinflammatory diseases: role of inflammasomes in autoinflammatory syndromes. Clin Exp Immunol. 2012; 167 (3): 382-90.
-
(2012)
Clin Exp Immunol.
, vol.167
, Issue.3
, pp. 382-390
-
-
Ozkurede, V.U.1
Franchi, L.2
-
22
-
-
84882285470
-
Specific inflammasomes in complex diseases
-
Masters SL. Specific inflammasomes in complex diseases. Clin Immunol. 2013; 147 (3): 223-8.
-
(2013)
Clin Immunol.
, vol.147
, Issue.3
, pp. 223-228
-
-
Masters, S.L.1
-
23
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, Speert D, Fernandes-Alnemri T, Wu J, Monks BG, Fitzgerald KA, Hornung V, Latz E. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol. 2009; 183 (2): 787-91.
-
(2009)
J Immunol.
, vol.183
, Issue.2
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
McDonald, K.5
Speert, D.6
Fernandes-Alnemri, T.7
Wu, J.8
Monks, B.G.9
Fitzgerald, K.A.10
Hornung, V.11
Latz, E.12
-
24
-
-
70249110860
-
Cutting edge: TNFalpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation
-
Franchi L, Eigenbrod T, Nunez G. Cutting edge: TNFalpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation. J Immunol. 2009; 183 (2): 792-6.
-
(2009)
J Immunol.
, vol.183
, Issue.2
, pp. 792-796
-
-
Franchi, L.1
Eigenbrod, T.2
Nunez, G.3
-
25
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, Roose-Girma M, Lee WP, Weinrauch Y, Monack DM, Dixit VM. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature. 2006; 440 (7081): 228-32.
-
(2006)
Nature.
, vol.440
, Issue.7081
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
26
-
-
79958040762
-
Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway
-
Niemi K, Teirila L, Lappalainen J, Rajamaki K, Baumann MH, Oorni K, Wolff H, Kovanen PT, Matikainen S, Eklund KK. Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway. J Immunol. 2011; 186 (11): 6119-28.
-
(2011)
J Immunol.
, vol.186
, Issue.11
, pp. 6119-6128
-
-
Niemi, K.1
Teirila, L.2
Lappalainen, J.3
Rajamaki, K.4
Baumann, M.H.5
Oorni, K.6
Wolff, H.7
Kovanen, P.T.8
Matikainen, S.9
Eklund, K.K.10
-
27
-
-
84859515412
-
Sphingosine regulates the NLRP3-inflammasome and IL-1βeta release from macrophages
-
Luheshi NM, Giles JA, Lopez-Castejon G, Brough D. Sphingosine regulates the NLRP3-inflammasome and IL-1βeta release from macrophages. Eur J Immunol. 2012; 42 (3): 716-25.
-
(2012)
Eur J Immunol.
, vol.42
, Issue.3
, pp. 716-725
-
-
Luheshi, N.M.1
Giles, J.A.2
Lopez-Castejon, G.3
Brough, D.4
-
28
-
-
84872723949
-
Neutrophil extracellular trap-associated protein activation of the NLRP3 inflammasome is enhanced in lupus macrophages
-
Kahlenberg JM, Carmona-Rivera C, Smith CK, Kaplan MJ. Neutrophil extracellular trap-associated protein activation of the NLRP3 inflammasome is enhanced in lupus macrophages. J Immunol. 2013; 190 (3): 1217-26.
-
(2013)
J Immunol.
, vol.190
, Issue.3
, pp. 1217-1226
-
-
Kahlenberg, J.M.1
Carmona-Rivera, C.2
Smith, C.K.3
Kaplan, M.J.4
-
29
-
-
79955038882
-
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
-
Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT, Brickey WJ, Ting JP. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol. 2011; 12 (5): 408-15.
-
(2011)
Nat Immunol.
, vol.12
, Issue.5
, pp. 408-415
-
-
Wen, H.1
Gris, D.2
Lei, Y.3
Jha, S.4
Zhang, L.5
Huang, M.T.6
Brickey, W.J.7
Ting, J.P.8
-
30
-
-
79959573042
-
Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells
-
Csak T, Ganz M, Pespisa J, Kodys K, Dolganiuc A, Szabo G. Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells. Hepatology. 2011; 54 (1): 133-44.
-
(2011)
Hepatology.
, vol.54
, Issue.1
, pp. 133-144
-
-
Csak, T.1
Ganz, M.2
Pespisa, J.3
Kodys, K.4
Dolganiuc, A.5
Szabo, G.6
-
31
-
-
79751512463
-
The NLRP3 inflammasome instigates obesityinduced inflammation and insulin resistance
-
Vandanmagsar B, Youm YH, Ravussin A, Galgani JE, Stadler K, Mynatt RL, Ravussin E, Stephens JM, Dixit VD. The NLRP3 inflammasome instigates obesityinduced inflammation and insulin resistance. Nat Med. 2011; 17 (2): 179-88.
-
(2011)
Nat Med.
, vol.17
, Issue.2
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.H.2
Ravussin, A.3
Galgani, J.E.4
Stadler, K.5
Mynatt, R.L.6
Ravussin, E.7
Stephens, J.M.8
Dixit, V.D.9
-
32
-
-
84896844884
-
Histones trigger sterile inflammation by activating the NLRP3 inflammasome
-
Aug 20. [Epub ahead of print]
-
Allam R, Darisipudi MN, Tschopp J, Anders HJ. Histones trigger sterile inflammation by activating the NLRP3 inflammasome. Eur J Immunol. 2013 Aug 20. [Epub ahead of print].
-
(2013)
Eur J Immunol.
-
-
Allam, R.1
Darisipudi, M.N.2
Tschopp, J.3
Anders, H.J.4
-
33
-
-
84880667818
-
Cutting edge: The NLRP3 inflammasome links complement-mediated inflammation and IL-1β release
-
Laudisi F, Spreafico R, Evrard M, Hughes TR, Mandriani B, Kandasamy M, Morgan BP, Sivasankar B, Mortellaro A. Cutting edge: the NLRP3 inflammasome links complement-mediated inflammation and IL-1β release. J Immunol. 2013; 191 (3): 1006-10.
-
(2013)
J Immunol.
, vol.191
, Issue.3
, pp. 1006-1010
-
-
Laudisi, F.1
Spreafico, R.2
Evrard, M.3
Hughes, T.R.4
Mandriani, B.5
Kandasamy, M.6
Morgan, B.P.7
Sivasankar, B.8
Mortellaro, A.9
-
34
-
-
84880651157
-
The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation
-
Triantafilou K, Hughes TR, Triantafilou M, Morgan BP. The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation. J Cell Sci. 2013; 126 (Pt 13): 2903-13.
-
(2013)
J Cell Sci.
, vol.126
, Issue.PART 13
, pp. 2903-2913
-
-
Triantafilou, K.1
Hughes, T.R.2
Triantafilou, M.3
Morgan, B.P.4
-
35
-
-
84888240043
-
C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation
-
Asgari E, Le Friec G, Yamamoto H, Perucha E, Sacks SS, Köhl J, Cook HT, Kemper C. C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation. Blood. 2013; 122 (20): 3473-81.
-
(2013)
Blood.
, vol.122
, Issue.20
, pp. 3473-3481
-
-
Asgari, E.1
Le Friec, G.2
Yamamoto, H.3
Perucha, E.4
Sacks, S.S.5
Köhl, J.6
Cook, H.T.7
Kemper, C.8
-
36
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nunez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature. 2010; 464 (7293): 1357-61.
-
(2010)
Nature.
, vol.464
, Issue.7293
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
Abela, G.S.7
Franchi, L.8
Nunez, G.9
Schnurr, M.10
Espevik, T.11
Lien, E.12
Fitzgerald, K.A.13
Rock, K.L.14
Moore, K.J.15
Wright, S.D.16
Hornung, V.17
Latz, E.18
-
37
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, Golenbock DT. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol. 2008; 9 (8): 857-65.
-
(2008)
Nat Immunol.
, vol.9
, Issue.8
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
Fitzgerald, K.A.7
Latz, E.8
Moore, K.J.9
Golenbock, D.T.10
-
38
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1βeta in type 2 diabetes
-
Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nunez G, Yodoi J, Kahn SE, Lavelle EC, O'Neill LA. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1βeta in type 2 diabetes. Nat Immunol. 2010; 11 (10): 897-904.
-
(2010)
Nat Immunol.
, vol.11
, Issue.10
, pp. 897-904
-
-
Masters, S.L.1
Dunne, A.2
Subramanian, S.L.3
Hull, R.L.4
Tannahill, G.M.5
Sharp, F.A.6
Becker, C.7
Franchi, L.8
Yoshihara, E.9
Chen, Z.10
Mullooly, N.11
Mielke, L.A.12
Harris, J.13
Coll, R.C.14
Mills, K.H.15
Mok, K.H.16
Newsholme, P.17
Nunez, G.18
Yodoi, J.19
Kahn, S.E.20
Lavelle, E.C.21
O'Neill, L.A.22
more..
-
39
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature. 2006; 440 (7081): 237-41.
-
(2006)
Nature.
, vol.440
, Issue.7081
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
40
-
-
79951846190
-
Basic calcium phosphate crystals induce monocyte/macrophage IL-1βeta secretion through the NLRP3 inflammasome in vitro
-
Pazar B, Ea HK, Narayan S, Kolly L, Bagnoud N, Chobaz V, Roger T, Liote F, So A, Busso N. Basic calcium phosphate crystals induce monocyte/macrophage IL-1βeta secretion through the NLRP3 inflammasome in vitro. J Immunol. 2011; 186 (4): 2495-502.
-
(2011)
J Immunol.
, vol.186
, Issue.4
, pp. 2495-2502
-
-
Pazar, B.1
Ea, H.K.2
Narayan, S.3
Kolly, L.4
Bagnoud, N.5
Chobaz, V.6
Roger, T.7
Liote, F.8
So, A.9
Busso, N.10
-
41
-
-
84873827527
-
Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1βeta secretion
-
Mulay SR, Kulkarni OP, Rupanagudi KV, Migliorini A, Darisipudi MN, Vilaysane A, Muruve D, Shi Y, Munro F, Liapis H, Anders HJ. Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1βeta secretion. J Clin Invest. 2013; 123 (1): 236-46.
-
(2013)
J Clin Invest.
, vol.123
, Issue.1
, pp. 236-246
-
-
Mulay, S.R.1
Kulkarni, O.P.2
Rupanagudi, K.V.3
Migliorini, A.4
Darisipudi, M.N.5
Vilaysane, A.6
Muruve, D.7
Shi, Y.8
Munro, F.9
Liapis, H.10
Anders, H.J.11
-
42
-
-
84868618082
-
Uromodulin triggers IL-1β-dependent innate immunity via the NLRP3 inflammasome
-
Darisipudi MN, Thomasova D, Mulay SR, Brech D, Noessner E, Liapis H, Anders HJ. Uromodulin triggers IL-1β-dependent innate immunity via the NLRP3 inflammasome. J Am Soc Nephrol. 2012; 23 (11): 1783-9.
-
(2012)
J Am Soc Nephrol.
, vol.23
, Issue.11
, pp. 1783-1789
-
-
Darisipudi, M.N.1
Thomasova, D.2
Mulay, S.R.3
Brech, D.4
Noessner, E.5
Liapis, H.6
Anders, H.J.7
-
43
-
-
34250835251
-
The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes
-
Feldmeyer L, Keller M, Niklaus G, Hohl D, Werner S, Beer HD. The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes. Curr Biol. 2007; 17 (13): 1140-5.
-
(2007)
Curr Biol.
, vol.17
, Issue.13
, pp. 1140-1145
-
-
Feldmeyer, L.1
Keller, M.2
Niklaus, G.3
Hohl, D.4
Werner, S.5
Beer, H.D.6
-
44
-
-
7944232105
-
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome
-
Martinon F, Agostini L, Meylan E, Tschopp J. Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr Biol. 2004; 14 (21): 1929-34.
-
(2004)
Curr Biol.
, vol.14
, Issue.21
, pp. 1929-1934
-
-
Martinon, F.1
Agostini, L.2
Meylan, E.3
Tschopp, J.4
-
45
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
Kanneganti TD, Ozoren N, Body-Malapel M, Amer A, Park JH, Franchi L, Whitfield J, Barchet W, Colonna M, Vandenabeele P, Bertin J, Coyle A, Grant EP, Akira S, Nunez G. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature. 2006; 440 (7081): 233-6.
-
(2006)
Nature.
, vol.440
, Issue.7081
, pp. 233-236
-
-
Kanneganti, T.D.1
Ozoren, N.2
Body-Malapel, M.3
Amer, A.4
Park, J.H.5
Franchi, L.6
Whitfield, J.7
Barchet, W.8
Colonna, M.9
Vandenabeele, P.10
Bertin, J.11
Coyle, A.12
Grant, E.P.13
Akira, S.14
Nunez, G.15
-
46
-
-
84872086179
-
Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth
-
Bruchard M, Mignot G, Derangère V, Chalmin F, Chevriaux A, Végran F, Boireau W, Simon B, Ryffel B, Connat JL, Kanellopoulos J, Martin F, Rébé C, Apetoh L, Ghiringhelli F. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nat Med. 2013; 19 (1): 57-64.
-
(2013)
Nat Med.
, vol.19
, Issue.1
, pp. 57-64
-
-
Bruchard, M.1
Mignot, G.2
Derangère, V.3
Chalmin, F.4
Chevriaux, A.5
Végran, F.6
Boireau, W.7
Simon, B.8
Ryffel, B.9
Connat, J.L.10
Kanellopoulos, J.11
Martin, F.12
Rébé, C.13
Apetoh, L.14
Ghiringhelli, F.15
-
47
-
-
79952747168
-
Cutting edge: Cyclic polypeptide and aminoglycoside antibiotics trigger IL-1β secretion by activating the NLRP3 inflammasome
-
Allam R, Darisipudi MN, Rupanagudi KV, Lichtnekert J, Tschopp J, Anders HJ. Cutting edge: cyclic polypeptide and aminoglycoside antibiotics trigger IL-1β secretion by activating the NLRP3 inflammasome. J Immunol. 2011; 186 (5): 2714-8.
-
(2011)
J Immunol.
, vol.186
, Issue.5
, pp. 2714-2718
-
-
Allam, R.1
Darisipudi, M.N.2
Rupanagudi, K.V.3
Lichtnekert, J.4
Tschopp, J.5
Anders, H.J.6
-
48
-
-
84882614243
-
Mitochondrial cardiolipin is required for nlrp3 inflammasome activation
-
Iyer SS, He Q, Janczy JR, Elliott EI, Zhong Z, Olivier AK, Sadler JJ, Knepper-Adrian V, Han R, Qiao L, Eisenbarth SC, Nauseef WM, Cassel SL, Sutterwala FS. Mitochondrial cardiolipin is required for nlrp3 inflammasome activation. Immunity. 2013; 39 (2): 311-23.
-
(2013)
Immunity.
, vol.39
, Issue.2
, pp. 311-323
-
-
Iyer, S.S.1
He, Q.2
Janczy, J.R.3
Elliott, E.I.4
Zhong, Z.5
Olivier, A.K.6
Sadler, J.J.7
Knepper-Adrian, V.8
Han, R.9
Qiao, L.10
Eisenbarth, S.C.11
Nauseef, W.M.12
Cassel, S.L.13
Sutterwala, F.S.14
-
49
-
-
68349157477
-
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
-
Dostert C, Guarda G, Romero JF, Menu P, Gross O, Tardivel A, Suva ML, Stehle JC, Kopf M, Stamenkovic I, Corradin G, Tschopp J. Malarial hemozoin is a Nalp3 inflammasome activating danger signal. PLoS One. 2009; 4 (8): e6510.
-
(2009)
PLoS One.
, vol.4
, Issue.8
-
-
Dostert, C.1
Guarda, G.2
Romero, J.F.3
Menu, P.4
Gross, O.5
Tardivel, A.6
Suva, M.L.7
Stehle, J.C.8
Kopf, M.9
Stamenkovic, I.10
Corradin, G.11
Tschopp, J.12
-
50
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol. 2008; 9 (8): 847-56.
-
(2008)
Nat Immunol.
, vol.9
, Issue.8
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
51
-
-
80053320089
-
Long, needle-like carbon nanotubes and asbestos activate the NLRP3 inflammasome through a similar mechanism
-
Palomaki J, Valimaki E, Sund J, Vippola M, Clausen PA, Jensen KA, Savolainen K, Matikainen S, Alenius H. Long, needle-like carbon nanotubes and asbestos activate the NLRP3 inflammasome through a similar mechanism. ACS Nano. 2011; 5 (9): 6861-70.
-
(2011)
ACS Nano.
, vol.5
, Issue.9
, pp. 6861-6870
-
-
Palomaki, J.1
Valimaki, E.2
Sund, J.3
Vippola, M.4
Clausen, P.A.5
Jensen, K.A.6
Savolainen, K.7
Matikainen, S.8
Alenius, H.9
-
52
-
-
84864106367
-
Double-walled carbon nanotubes trigger IL-1β release in human monocytes through Nlrp3 inflammasome activation
-
Meunier E, Coste A, Olagnier D, Authier H, Lefevre L, Dardenne C, Bernad J, Beraud M, Flahaut E, Pipy B. Double-walled carbon nanotubes trigger IL-1β release in human monocytes through Nlrp3 inflammasome activation. Nanomedicine. 2012; 8 (6): 987-95.
-
(2012)
Nanomedicine.
, vol.8
, Issue.6
, pp. 987-995
-
-
Meunier, E.1
Coste, A.2
Olagnier, D.3
Authier, H.4
Lefevre, L.5
Dardenne, C.6
Bernad, J.7
Beraud, M.8
Flahaut, E.9
Pipy, B.10
-
53
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature. 2008; 453 (7198): 1122-6.
-
(2008)
Nature.
, vol.453
, Issue.7198
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor, W.3
Sutterwala, F.S.4
Flavell, R.A.5
-
54
-
-
47849087075
-
Cutting edge: Inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3
-
Li H, Willingham SB, Ting JP, Re F. Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J Immunol. 2008; 181 (1): 17-21.
-
(2008)
J Immunol.
, vol.181
, Issue.1
, pp. 17-21
-
-
Li, H.1
Willingham, S.B.2
Ting, J.P.3
Re, F.4
-
55
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science. 2008; 320 (5876): 674-7.
-
(2008)
Science.
, vol.320
, Issue.5876
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
56
-
-
47849132947
-
The Nalp3 inflammasome is essential for the development of silicosis
-
Cassel SL, Eisenbarth SC, Iyer SS, Sadler JJ, Colegio OR, Tephly LA, Carter AB, Rothman PB, Flavell RA, Sutterwala FS. The Nalp3 inflammasome is essential for the development of silicosis. Proc Natl Acad Sci U S A. 2008; 105 (26): 9035-40.
-
(2008)
Proc Natl Acad Sci U S A.
, vol.105
, Issue.26
, pp. 9035-9040
-
-
Cassel, S.L.1
Eisenbarth, S.C.2
Iyer, S.S.3
Sadler, J.J.4
Colegio, O.R.5
Tephly, L.A.6
Carter, A.B.7
Rothman, P.B.8
Flavell, R.A.9
Sutterwala, F.S.10
-
57
-
-
78650610580
-
Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1β
-
Yazdi AS, Guarda G, Riteau N, Drexler SK, Tardivel A, Couillin I, Tschopp J. Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1β. Proc Natl Acad Sci U S A. 2010; 107 (45): 19449-54.
-
(2010)
Proc Natl Acad Sci U S A.
, vol.107
, Issue.45
, pp. 19449-19454
-
-
Yazdi, A.S.1
Guarda, G.2
Riteau, N.3
Drexler, S.K.4
Tardivel, A.5
Couillin, I.6
Tschopp, J.7
-
58
-
-
84879923140
-
Particle size of latex beads dictates IL-1β production mechanism
-
Adachi T, Takahara K, Taneo J, Uchiyama Y, Inaba K. Particle size of latex beads dictates IL-1β production mechanism. PLoS One. 2013; 8 (7): e68499.
-
(2013)
PLoS One.
, vol.8
, Issue.7
-
-
Adachi, T.1
Takahara, K.2
Taneo, J.3
Uchiyama, Y.4
Inaba, K.5
-
59
-
-
79958811218
-
Doxorubicin and daunorubicin induce processing and release of interleukin-1β through activation of the NLRP3 inflammasome
-
Sauter KA, Wood LJ, Wong J, Iordanov M, Magun BE. Doxorubicin and daunorubicin induce processing and release of interleukin-1β through activation of the NLRP3 inflammasome. Cancer Biol Ther. 2011; 11 (12): 1008-16.
-
(2011)
Cancer Biol Ther.
, vol.11
, Issue.12
, pp. 1008-1016
-
-
Sauter, K.A.1
Wood, L.J.2
Wong, J.3
Iordanov, M.4
Magun, B.E.5
-
60
-
-
84885966098
-
Proapoptotic Chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells
-
Antonopoulos C, El Sanadi C, Kaiser WJ, Mocarski ES, Dubyak GR. Proapoptotic Chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells. J Immunol. 2013; 191 (9): 4789-803.
-
(2013)
J Immunol.
, vol.191
, Issue.9
, pp. 4789-4803
-
-
Antonopoulos, C.1
El Sanadi, C.2
Kaiser, W.J.3
Mocarski, E.S.4
Dubyak, G.R.5
-
61
-
-
84875464393
-
Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretchinduced lung inflammation and injury
-
Wu J, Yan Z, Schwartz DE, Yu J, Malik AB, Hu G. Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretchinduced lung inflammation and injury. J Immunol. 2013; 190 (7): 3590-9.
-
(2013)
J Immunol.
, vol.190
, Issue.7
, pp. 3590-3599
-
-
Wu, J.1
Yan, Z.2
Schwartz, D.E.3
Yu, J.4
Malik, A.B.5
Hu, G.6
-
62
-
-
84877705901
-
Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome
-
Rajamaki K, Nordstrom T, Nurmi K, Akerman KE, Kovanen PT, Oorni K, Eklund KK. Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome. J Biol Chem. 2013; 288 (19): 13410-9.
-
(2013)
J Biol Chem.
, vol.288
, Issue.19
, pp. 13410-13419
-
-
Rajamaki, K.1
Nordstrom, T.2
Nurmi, K.3
Akerman, K.E.4
Kovanen, P.T.5
Oorni, K.6
Eklund, K.K.7
-
63
-
-
84856857478
-
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway
-
Menu P, Mayor A, Zhou R, Tardivel A, Ichijo H, Mori K, Tschopp J. ER stress activates the NLRP3 inflammasome via an UPR-independent pathway. Cell Death Dis. 2012; 3: e261.
-
(2012)
Cell Death Dis.
, vol.3
-
-
Menu, P.1
Mayor, A.2
Zhou, R.3
Tardivel, A.4
Ichijo, H.5
Mori, K.6
Tschopp, J.7
-
64
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
-
Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozoren N, Jagirdar R, Inohara N, Vandenabeele P, Bertin J, Coyle A, Grant EP, Nunez G. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol. 2006; 7 (6): 576-82.
-
(2006)
Nat Immunol.
, vol.7
, Issue.6
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
Kanneganti, T.D.4
Ozoren, N.5
Jagirdar, R.6
Inohara, N.7
Vandenabeele, P.8
Bertin, J.9
Coyle, A.10
Grant, E.P.11
Nunez, G.12
-
65
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
-
Miao EA, Alpuche-Aranda CM, Dors M, Clark AE, Bader MW, Miller SI, Aderem A. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat Immunol. 2006; 7 (6): 569-75.
-
(2006)
Nat Immunol.
, vol.7
, Issue.6
, pp. 569-575
-
-
Miao, E.A.1
Alpuche-Aranda, C.M.2
Dors, M.3
Clark, A.E.4
Bader, M.W.5
Miller, S.I.6
Aderem, A.7
-
66
-
-
77649241461
-
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
-
Miao EA, Mao DP, Yudkovsky N, Bonneau R, Lorang CG, Warren SE, Leaf IA, Aderem A. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc Natl Acad Sci U S A. 2010; 107 (7): 3076-80.
-
(2010)
Proc Natl Acad Sci U S A.
, vol.107
, Issue.7
, pp. 3076-3080
-
-
Miao, E.A.1
Mao, D.P.2
Yudkovsky, N.3
Bonneau, R.4
Lorang, C.G.5
Warren, S.E.6
Leaf, I.A.7
Aderem, A.8
-
67
-
-
80053349020
-
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
-
Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, Liu L, Shao F. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature. 2011; 477 (7366): 596-600.
-
(2011)
Nature.
, vol.477
, Issue.7366
, pp. 596-600
-
-
Zhao, Y.1
Yang, J.2
Shi, J.3
Gong, Y.N.4
Lu, Q.5
Xu, H.6
Liu, L.7
Shao, F.8
-
68
-
-
84883329029
-
Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation
-
Yang J, Zhao Y, Shi J, Shao F. Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation. Proc Natl Acad Sci U S A. 2013; 110 (35): 14408-13.
-
(2013)
Proc Natl Acad Sci U S A.
, vol.110
, Issue.35
, pp. 14408-14413
-
-
Yang, J.1
Zhao, Y.2
Shi, J.3
Shao, F.4
-
69
-
-
31744441475
-
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
-
Boyden ED, Dietrich WF. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet. 2006; 38 (2): 240-4.
-
(2006)
Nat Genet.
, vol.38
, Issue.2
, pp. 240-244
-
-
Boyden, E.D.1
Dietrich, W.F.2
-
70
-
-
0032130971
-
The Ifi 200 genes: An emerging family of IFN-inducible genes
-
Landolfo S, Gariglio M, Gribaudo G, Lembo D. The Ifi 200 genes: an emerging family of IFN-inducible genes. Biochimie. 1998; 80 (8-9): 721-8.
-
(1998)
Biochimie.
, vol.80
, Issue.8-9
, pp. 721-728
-
-
Landolfo, S.1
Gariglio, M.2
Gribaudo, G.3
Lembo, D.4
-
71
-
-
60749104535
-
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
Roberts TL, Idris A, Dunn JA, Kelly GM, Burnton CM, Hodgson S, Hardy LL, Garceau V, Sweet MJ, Ross IL, Hume DA, Stacey KJ. HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science. 2009; 323 (5917): 1057-60.
-
(2009)
Science.
, vol.323
, Issue.5917
, pp. 1057-1060
-
-
Roberts, T.L.1
Idris, A.2
Dunn, J.A.3
Kelly, G.M.4
Burnton, C.M.5
Hodgson, S.6
Hardy, L.L.7
Garceau, V.8
Sweet, M.J.9
Ross, I.L.10
Hume, D.A.11
Stacey, K.J.12
-
72
-
-
79956061094
-
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi sarcoma-associated herpesvirus infection
-
Kerur N, Veettil MV, Sharma-Walia N, Bottero V, Sadagopan S, Otageri P, Chandran B. IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi sarcoma-associated herpesvirus infection. Cell Host Microbe. 2011; 9 (5): 363-75.
-
(2011)
Cell Host Microbe.
, vol.9
, Issue.5
, pp. 363-375
-
-
Kerur, N.1
Veettil, M.V.2
Sharma-Walia, N.3
Bottero, V.4
Sadagopan, S.5
Otageri, P.6
Chandran, B.7
-
73
-
-
80555133274
-
Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection
-
Fang R, Tsuchiya K, Kawamura I, Shen Y, Hara H, Sakai S, Yamamoto T, Fernandes-Alnemri T, Yang R, Hernandez-Cuellar E, Dewamitta SR, Xu Y, Qu H, Alnemri ES, Mitsuyama M. Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection. J Immunol. 2011; 187 (9): 4890-9.
-
(2011)
J Immunol.
, vol.187
, Issue.9
, pp. 4890-4899
-
-
Fang, R.1
Tsuchiya, K.2
Kawamura, I.3
Shen, Y.4
Hara, H.5
Sakai, S.6
Yamamoto, T.7
Fernandes-Alnemri, T.8
Yang, R.9
Hernandez-Cuellar, E.10
Dewamitta, S.R.11
Xu, Y.12
Qu, H.13
Alnemri, E.S.14
Mitsuyama, M.15
-
74
-
-
79959369355
-
Nod-like receptor pyrin domaincontaining protein 6 (NLRP6) controls epithelial selfrenewal and colorectal carcinogenesis upon injury
-
Normand S, Delanoye-Crespin A, Bressenot A, Huot L, Grandjean T, Peyrin-Biroulet L, Lemoine Y, Hot D, Chamaillard M. Nod-like receptor pyrin domaincontaining protein 6 (NLRP6) controls epithelial selfrenewal and colorectal carcinogenesis upon injury. Proc Natl Acad Sci U S A. 2011; 108 (23): 9601-6.
-
(2011)
Proc Natl Acad Sci U S A.
, vol.108
, Issue.23
, pp. 9601-9606
-
-
Normand, S.1
Delanoye-Crespin, A.2
Bressenot, A.3
Huot, L.4
Grandjean, T.5
Peyrin-Biroulet, L.6
Lemoine, Y.7
Hot, D.8
Chamaillard, M.9
-
75
-
-
79957576718
-
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
-
Elinav E, Strowig T, Kau AL, Henao-Mejia J, Thaiss CA, Booth CJ, Peaper DR, Bertin J, Eisenbarth SC, Gordon JI, Flavell RA. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell. 2011; 145 (5): 745-57.
-
(2011)
Cell.
, vol.145
, Issue.5
, pp. 745-757
-
-
Elinav, E.1
Strowig, T.2
Kau, A.L.3
Henao-Mejia, J.4
Thaiss, C.A.5
Booth, C.J.6
Peaper, D.R.7
Bertin, J.8
Eisenbarth, S.C.9
Gordon, J.I.10
Flavell, R.A.11
-
76
-
-
79959540809
-
A functional role for Nlrp6 in intestinal inflammation and tumorigenesis
-
Chen GY, Liu M, Wang F, Bertin J, Nunez G. A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J Immunol. 2011; 186 (12): 7187-94.
-
(2011)
J Immunol.
, vol.186
, Issue.12
, pp. 7187-7194
-
-
Chen, G.Y.1
Liu, M.2
Wang, F.3
Bertin, J.4
Nunez, G.5
-
77
-
-
84884126316
-
NLRP6 in infection and inflammation
-
Anand PK, Kanneganti TD. NLRP6 in infection and inflammation. Microbes Infect. 2013; 15 (10-11): 661-8.
-
(2013)
Microbes Infect.
, vol.15
, Issue.10-11
, pp. 661-668
-
-
Anand, P.K.1
Kanneganti, T.D.2
-
78
-
-
84858796861
-
An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages
-
Khare S, Dorfleutner A, Bryan NB, Yun C, Radian AD, de Almeida L, Rojanasakul Y, Stehlik C. An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages. Immunity. 2012; 36 (3): 464-76.
-
(2012)
Immunity.
, vol.36
, Issue.3
, pp. 464-476
-
-
Khare, S.1
Dorfleutner, A.2
Bryan, N.B.3
Yun, C.4
Radian, A.D.5
de Almeida, L.6
Rojanasakul, Y.7
Stehlik, C.8
-
79
-
-
84864317101
-
The NLRP12 inflammasome recognizes Yersinia pestis
-
Vladimer GI, Weng D, Paquette SW, Vanaja SK, Rathinam VA, Aune MH, Conlon JE, Burbage JJ, Proulx MK, Liu Q, Reed G, Mecsas JC, Iwakura Y, Bertin J, Goguen JD, Fitzgerald KA, Lien E. The NLRP12 inflammasome recognizes Yersinia pestis. Immunity. 2012; 37 (1): 96-107.
-
(2012)
Immunity.
, vol.37
, Issue.1
, pp. 96-107
-
-
Vladimer, G.I.1
Weng, D.2
Paquette, S.W.3
Vanaja, S.K.4
Rathinam, V.A.5
Aune, M.H.6
Conlon, J.E.7
Burbage, J.J.8
Proulx, M.K.9
Liu, Q.10
Reed, G.11
Mecsas, J.C.12
Iwakura, Y.13
Bertin, J.14
Goguen, J.D.15
Fitzgerald, K.A.16
Lien, E.17
-
80
-
-
35348934890
-
Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants
-
Yu JW, Fernandes-Alnemri T, Datta P, Wu J, Juliana C, Solorzano L, McCormick M, Zhang Z, Alnemri ES. Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants. Mol Cell. 2007; 28 (2): 214-27.
-
(2007)
Mol Cell.
, vol.28
, Issue.2
, pp. 214-227
-
-
Yu, J.W.1
Fernandes-Alnemri, T.2
Datta, P.3
Wu, J.4
Juliana, C.5
Solorzano, L.6
McCormick, M.7
Zhang, Z.8
Alnemri, E.S.9
-
81
-
-
84876518121
-
Ribotoxic stress through p38 mitogenactivated protein kinase activates in vitro the human pyrin inflammasome
-
Yu JW, Farias A, Hwang I, Fernandes-Alnemri T, Alnemri ES. Ribotoxic stress through p38 mitogenactivated protein kinase activates in vitro the human pyrin inflammasome. J Biol Chem. 2013; 288 (16): 11378-83.
-
(2013)
J Biol Chem.
, vol.288
, Issue.16
, pp. 11378-11383
-
-
Yu, J.W.1
Farias, A.2
Hwang, I.3
Fernandes-Alnemri, T.4
Alnemri, E.S.5
-
82
-
-
84859403876
-
Activation of the pyrin inflammasome by intracellular Burkholderia cenocepacia
-
Gavrilin MA, Abdelaziz DH, Mostafa M, Abdulrahman BA, Grandhi J, Akhter A, Abu Khweek A, Aubert DF, Valvano MA, Wewers MD, Amer AO. Activation of the pyrin inflammasome by intracellular Burkholderia cenocepacia. J Immunol. 2012; 188 (7): 3469-77.
-
(2012)
J Immunol.
, vol.188
, Issue.7
, pp. 3469-3477
-
-
Gavrilin, M.A.1
Abdelaziz, D.H.2
Mostafa, M.3
Abdulrahman, B.A.4
Grandhi, J.5
Akhter, A.6
Abu Khweek, A.7
Aubert, D.F.8
Valvano, M.A.9
Wewers, M.D.10
Amer, A.O.11
-
83
-
-
67649160593
-
Pyrin critical to macrophage IL-1beta response to Francisella challenge
-
Gavrilin MA, Mitra S, Seshadri S, Nateri J, Berhe F, Hall MW, Wewers MD. Pyrin critical to macrophage IL-1beta response to Francisella challenge. J Immunol. 2009; 182 (12): 7982-9.
-
(2009)
J Immunol.
, vol.182
, Issue.12
, pp. 7982-7989
-
-
Gavrilin, M.A.1
Mitra, S.2
Seshadri, S.3
Nateri, J.4
Berhe, F.5
Hall, M.W.6
Wewers, M.D.7
-
84
-
-
84870595842
-
Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels
-
Hesker PR, Nguyen M, Kovarova M, Ting JP, Koller BH. Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels. PLoS One. 2012; 7 (11): e51105.
-
(2012)
PLoS One.
, vol.7
, Issue.11
-
-
Hesker, P.R.1
Nguyen, M.2
Kovarova, M.3
Ting, J.P.4
Koller, B.H.5
-
85
-
-
79956299492
-
Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice
-
Chae JJ, Cho YH, Lee GS, Cheng J, Liu PP, Feigenbaum L, Katz SI, Kastner DL. Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice. Immunity. 2011; 34 (5): 755-68.
-
(2011)
Immunity.
, vol.34
, Issue.5
, pp. 755-768
-
-
Chae, J.J.1
Cho, Y.H.2
Lee, G.S.3
Cheng, J.4
Liu, P.P.5
Feigenbaum, L.6
Katz, S.I.7
Kastner, D.L.8
-
86
-
-
74049126045
-
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production
-
Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, Hannesschlager N, Schlee M, Rothenfusser S, Barchet W, Kato H, Akira S, Inoue S, Endres S, Peschel C, Hartmann G, Hornung V, Ruland J. Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production. Nat Immunol. 2010; 11 (1): 63-9.
-
(2010)
Nat Immunol.
, vol.11
, Issue.1
, pp. 63-69
-
-
Poeck, H.1
Bscheider, M.2
Gross, O.3
Finger, K.4
Roth, S.5
Rebsamen, M.6
Hannesschlager, N.7
Schlee, M.8
Rothenfusser, S.9
Barchet, W.10
Kato, H.11
Akira, S.12
Inoue, S.13
Endres, S.14
Peschel, C.15
Hartmann, G.16
Hornung, V.17
Ruland, J.18
-
87
-
-
67349271142
-
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
-
Gross O, Poeck H, Bscheider M, Dostert C, Hannesschlager N, Endres S, Hartmann G, Tardivel A, Schweighoffer E, Tybulewicz V, Mocsai A, Tschopp J, Ruland J. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature. 2009; 459 (7245): 433-6.
-
(2009)
Nature.
, vol.459
, Issue.7245
, pp. 433-436
-
-
Gross, O.1
Poeck, H.2
Bscheider, M.3
Dostert, C.4
Hannesschlager, N.5
Endres, S.6
Hartmann, G.7
Tardivel, A.8
Schweighoffer, E.9
Tybulewicz, V.10
Mocsai, A.11
Tschopp, J.12
Ruland, J.13
-
88
-
-
84857175933
-
Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome
-
Gringhuis SI, Kaptein TM, Wevers BA, Theelen B, van der Vlist M, Boekhout T, Geijtenbeek TB. Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome. Nat Immunol. 2012; 13 (3): 246-54.
-
(2012)
Nat Immunol.
, vol.13
, Issue.3
, pp. 246-254
-
-
Gringhuis, S.I.1
Kaptein, T.M.2
Wevers, B.A.3
Theelen, B.4
van der Vlist, M.5
Boekhout, T.6
Geijtenbeek, T.B.7
-
89
-
-
84871125002
-
Cutting edge: FAS (CD95) mediates noncanonical IL-1βeta and IL-18 maturation via caspase-8 in an RIP3-independent manner
-
Bossaller L, Chiang PI, Schmidt-Lauber C, Ganesan S, Kaiser WJ, Rathinam VA, Mocarski ES, Subramanian D, Green DR, Silverman N, Fitzgerald KA, Marshak-Rothstein A, Latz E. Cutting edge: FAS (CD95) mediates noncanonical IL-1βeta and IL-18 maturation via caspase-8 in an RIP3-independent manner. J Immunol. 2012; 189 (12): 5508-12.
-
(2012)
J Immunol.
, vol.189
, Issue.12
, pp. 5508-5512
-
-
Bossaller, L.1
Chiang, P.I.2
Schmidt-Lauber, C.3
Ganesan, S.4
Kaiser, W.J.5
Rathinam, V.A.6
Mocarski, E.S.7
Subramanian, D.8
Green, D.R.9
Silverman, N.10
Fitzgerald, K.A.11
Marshak-Rothstein, A.12
Latz, E.13
-
90
-
-
84875970670
-
Fas-mediated inflammatory response in Listeria monocytogenes infection
-
Uchiyama R, Yonehara S, Tsutsui H. Fas-mediated inflammatory response in Listeria monocytogenes infection. J Immunol. 2013; 190 (8): 4245-54.
-
(2013)
J Immunol.
, vol.190
, Issue.8
, pp. 4245-4254
-
-
Uchiyama, R.1
Yonehara, S.2
Tsutsui, H.3
-
91
-
-
51049100571
-
Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8
-
Maelfait J, Vercammen E, Janssens S, Schotte P, Haegman M, Magez S, Beyaert R. Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8. J Exp Med. 2008; 205 (9): 1967-73.
-
(2008)
J Exp Med.
, vol.205
, Issue.9
, pp. 1967-1973
-
-
Maelfait, J.1
Vercammen, E.2
Janssens, S.3
Schotte, P.4
Haegman, M.5
Magez, S.6
Beyaert, R.7
-
93
-
-
84874248044
-
Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1alpha, controlling necrosis-induced sterile inflammation
-
1
-
Zheng Y, Humphry M, Maguire JJ, Bennett MR, Clarke MC. Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1alpha, controlling necrosis-induced sterile inflammation. Immunity. 2013 1; 38 (2): 285-95.
-
(2013)
Immunity.
, vol.38
, Issue.2
, pp. 285-295
-
-
Zheng, Y.1
Humphry, M.2
Maguire, J.J.3
Bennett, M.R.4
Clarke, M.C.5
-
94
-
-
84858761335
-
Inflammasome activators induce interleukin-1alpha secretion via distinct pathways with differential requirement for the protease function of caspase-1
-
Gross O, Yazdi AS, Thomas CJ, Masin M, Heinz LX, Guarda G, Quadroni M, Drexler SK, Tschopp J. Inflammasome activators induce interleukin-1alpha secretion via distinct pathways with differential requirement for the protease function of caspase-1. Immunity. 2012; 36 (3): 388-400.
-
(2012)
Immunity.
, vol.36
, Issue.3
, pp. 388-400
-
-
Gross, O.1
Yazdi, A.S.2
Thomas, C.J.3
Masin, M.4
Heinz, L.X.5
Guarda, G.6
Quadroni, M.7
Drexler, S.K.8
Tschopp, J.9
-
95
-
-
81055145409
-
Inflammasome activation and IL-1β target IL-1α for secretion as opposed to surface expression
-
Fettelschoss A, Kistowska M, LeibundGut-Landmann S, Beer HD, Johansen P, Senti G, Contassot E, Bachmann MF, French LE, Oxenius A, Kündig TM. Inflammasome activation and IL-1β target IL-1α for secretion as opposed to surface expression. Proc Natl Acad Sci U S A. 2011; 108 (44): 18055-60.
-
(2011)
Proc Natl Acad Sci U S A.
, vol.108
, Issue.44
, pp. 18055-18060
-
-
Fettelschoss, A.1
Kistowska, M.2
LeibundGut-Landmann, S.3
Beer, H.D.4
Johansen, P.5
Senti, G.6
Contassot, E.7
Bachmann, M.F.8
French, L.E.9
Oxenius, A.10
Kündig, T.M.11
-
96
-
-
39749084641
-
Active caspase-1 is a regulator of unconventional protein secretion
-
Keller M, Rüegg A, Werner S, Beer HD. Active caspase-1 is a regulator of unconventional protein secretion. Cell. 2008; 132 (5): 818-31.
-
(2008)
Cell.
, vol.132
, Issue.5
, pp. 818-831
-
-
Keller, M.1
Rüegg, A.2
Werner, S.3
Beer, H.D.4
-
97
-
-
33749576792
-
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
-
Fink SL, Cookson BT. Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages. Cell Microbiol. 2006; 8 (11): 1812-25.
-
(2006)
Cell Microbiol.
, vol.8
, Issue.11
, pp. 1812-1825
-
-
Fink, S.L.1
Cookson, B.T.2
-
98
-
-
41949127121
-
Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
-
Fink SL, Bergsbaken T, Cookson BT. Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms. Proc Natl Acad Sci U S A. 2008; 105 (11): 4312-7.
-
(2008)
Proc Natl Acad Sci U S A.
, vol.105
, Issue.11
, pp. 4312-4317
-
-
Fink, S.L.1
Bergsbaken, T.2
Cookson, B.T.3
-
99
-
-
84878434348
-
Pyroptotic cells externalize eat-me and release find-me signals and are efficiently engulfed by macrophages
-
Wang Q, Imamura R, Motani K, Kushiyama H, Nagata S, Suda T. Pyroptotic cells externalize eat-me and release find-me signals and are efficiently engulfed by macrophages. Int Immunol. 2013; 25 (6): 363-72.
-
(2013)
Int Immunol.
, vol.25
, Issue.6
, pp. 363-372
-
-
Wang, Q.1
Imamura, R.2
Motani, K.3
Kushiyama, H.4
Nagata, S.5
Suda, T.6
-
100
-
-
77349118460
-
Pore formation triggered by Legionella spp. is an Nlrc4 inflammasome-dependent host cell response that precedes pyroptosis
-
Silveira TN, Zamboni DS. Pore formation triggered by Legionella spp. is an Nlrc4 inflammasome-dependent host cell response that precedes pyroptosis. Infect Immun. 2010; 78 (3): 1403-13.
-
(2010)
Infect Immun.
, vol.78
, Issue.3
, pp. 1403-1413
-
-
Silveira, T.N.1
Zamboni, D.S.2
-
101
-
-
78649897795
-
Cutting edge: Proteolytic inactivation of poly (ADPribose) polymerase 1 by the Nlrp3 and Nlrc4 inflammasomes
-
Malireddi RK, Ippagunta S, Lamkanfi M, Kanneganti TD. Cutting edge: proteolytic inactivation of poly (ADPribose) polymerase 1 by the Nlrp3 and Nlrc4 inflammasomes. J Immunol. 2010; 185 (6): 3127-30.
-
(2010)
J Immunol.
, vol.185
, Issue.6
, pp. 3127-3130
-
-
Malireddi, R.K.1
Ippagunta, S.2
Lamkanfi, M.3
Kanneganti, T.D.4
-
102
-
-
58149287750
-
Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes
-
Lamkanfi M, Kanneganti TD, Van Damme P, Vanden Berghe T, Vanoverberghe I, Vandekerckhove J, Vandenabeele P, Gevaert K, Nunez G. Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes. Mol Cell Proteomics. 2008; 7 (12): 2350-63.
-
(2008)
Mol Cell Proteomics.
, vol.7
, Issue.12
, pp. 2350-2363
-
-
Lamkanfi, M.1
Kanneganti, T.D.2
Van Damme, P.3
Vanden Berghe, T.4
Vanoverberghe, I.5
Vandekerckhove, J.6
Vandenabeele, P.7
Gevaert, K.8
Nunez, G.9
-
103
-
-
66349093381
-
Caspase-7 activation by the Nlrc4/Ipaf inflammasome restricts Legionella pneumophila infection
-
Akhter A, Gavrilin MA, Frantz L, Washington S, Ditty C, Limoli D, Day C, Sarkar A, Newland C, Butchar J, Marsh CB, Wewers MD, Tridandapani S, Kanneganti TD, Amer AO. Caspase-7 activation by the Nlrc4/Ipaf inflammasome restricts Legionella pneumophila infection. PLoS Pathog. 2009; 5 (4): e1000361.
-
(2009)
PLoS Pathog.
, vol.5
, Issue.4
-
-
Akhter, A.1
Gavrilin, M.A.2
Frantz, L.3
Washington, S.4
Ditty, C.5
Limoli, D.6
Day, C.7
Sarkar, A.8
Newland, C.9
Butchar, J.10
Marsh, C.B.11
Wewers, M.D.12
Tridandapani, S.13
Kanneganti, T.D.14
Amer, A.O.15
-
104
-
-
84860325913
-
Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-kappaB target genes
-
Erener S, Petrilli V, Kassner I, Minotti R, Castillo R, Santoro R, Hassa PO, Tschopp J, Hottiger MO. Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-kappaB target genes. Mol Cell. 2012; 46 (2): 200-11.
-
(2012)
Mol Cell.
, vol.46
, Issue.2
, pp. 200-211
-
-
Erener, S.1
Petrilli, V.2
Kassner, I.3
Minotti, R.4
Castillo, R.5
Santoro, R.6
Hassa, P.O.7
Tschopp, J.8
Hottiger, M.O.9
-
105
-
-
37549002511
-
The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock
-
Shao W, Yeretssian G, Doiron K, Hussain SN, Saleh M. The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock. J Biol Chem. 2007; 282 (50): 36321-9.
-
(2007)
J Biol Chem.
, vol.282
, Issue.50
, pp. 36321-36329
-
-
Shao, W.1
Yeretssian, G.2
Doiron, K.3
Hussain, S.N.4
Saleh, M.5
-
106
-
-
84867063450
-
Rapid induction of inflammatory lipid mediators by the inflammasome in vivo
-
von Moltke J, Trinidad NJ, Moayeri M, Kintzer AF, Wang SB, van Rooijen N, Brown CR, Krantz BA, Leppla SH, Gronert K, Vance RE. Rapid induction of inflammatory lipid mediators by the inflammasome in vivo. Nature. 2012; 490 (7418): 107-11.
-
(2012)
Nature.
, vol.490
, Issue.7418
, pp. 107-111
-
-
von Moltke, J.1
Trinidad, N.J.2
Moayeri, M.3
Kintzer, A.F.4
Wang, S.B.5
van Rooijen, N.6
Brown, C.R.7
Krantz, B.A.8
Leppla, S.H.9
Gronert, K.10
Vance, R.E.11
-
107
-
-
84878245034
-
Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function
-
Sokolovska A, Becker CE, Ip WK, Rathinam VA, Brudner M, Paquette N, Tanne A, Vanaja SK, Moore KJ, Fitzgerald KA, Lacy-Hulbert A, Stuart LM. Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function. Nat Immunol. 2013; 14 (6): 543-53.
-
(2013)
Nat Immunol.
, vol.14
, Issue.6
, pp. 543-553
-
-
Sokolovska, A.1
Becker, C.E.2
Ip, W.K.3
Rathinam, V.A.4
Brudner, M.5
Paquette, N.6
Tanne, A.7
Vanaja, S.K.8
Moore, K.J.9
Fitzgerald, K.A.10
Lacy-Hulbert, A.11
Stuart, L.M.12
-
108
-
-
33748598700
-
Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival
-
Gurcel L, Abrami L, Girardin S, Tschopp J, van der Goot FG. Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell. 2006; 126 (6): 1135-45.
-
(2006)
Cell.
, vol.126
, Issue.6
, pp. 1135-1145
-
-
Gurcel, L.1
Abrami, L.2
Girardin, S.3
Tschopp, J.4
van der Goot, F.G.5
-
109
-
-
78449269290
-
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
-
Miao EA, Leaf IA, Treuting PM, Mao DP, Dors M, Sarkar A, Warren SE, Wewers MD, Aderem A. Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria. Nat Immunol. 2010; 11 (12): 1136-42.
-
(2010)
Nat Immunol.
, vol.11
, Issue.12
, pp. 1136-1142
-
-
Miao, E.A.1
Leaf, I.A.2
Treuting, P.M.3
Mao, D.P.4
Dors, M.5
Sarkar, A.6
Warren, S.E.7
Wewers, M.D.8
Aderem, A.9
-
110
-
-
84879781288
-
Lose the battle to win the war: Bacterial strategies for evading host inflammasome activation
-
Higa N, Toma C, Nohara T, Nakasone N, Takaesu G, Suzuki T. Lose the battle to win the war: bacterial strategies for evading host inflammasome activation. Trends Microbiol. 2013; 21 (7): 342-9.
-
(2013)
Trends Microbiol.
, vol.21
, Issue.7
, pp. 342-349
-
-
Higa, N.1
Toma, C.2
Nohara, T.3
Nakasone, N.4
Takaesu, G.5
Suzuki, T.6
-
111
-
-
77952303410
-
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
-
May 10
-
Allen IC, TeKippe EM, Woodford RM, Uronis JM, Holl EK, Rogers AB, Herfarth HH, Jobin C, Ting JP. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J Exp Med. 2010 May 10; 207 (5): 1045-56.
-
(2010)
J Exp Med.
, vol.207
, Issue.5
, pp. 1045-1056
-
-
Allen, I.C.1
TeKippe, E.M.2
Woodford, R.M.3
Uronis, J.M.4
Holl, E.K.5
Rogers, A.B.6
Herfarth, H.H.7
Jobin, C.8
Ting, J.P.9
-
112
-
-
77950002937
-
The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
-
Mar 26
-
Zaki MH, Boyd KL, Vogel P, Kastan MB, Lamkanfi M, Kanneganti TD. The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity. 2010 Mar 26; 32 (3): 379-91.
-
(2010)
Immunity.
, vol.32
, Issue.3
, pp. 379-391
-
-
Zaki, M.H.1
Boyd, K.L.2
Vogel, P.3
Kastan, M.B.4
Lamkanfi, M.5
Kanneganti, T.D.6
-
113
-
-
79955846705
-
NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis
-
Jun
-
Hirota SA, Ng J, Lueng A, Khajah M, Parhar K, Li Y, Lam V, Potentier MS, Ng K, Bawa M, McCafferty DM, Rioux KP, Ghosh S, Xavier RJ, Colgan SP, Tschopp J, Muruve D, MacDonald JA, Beck PL. NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis. Inflamm Bowel Dis. 2011 Jun; 17 (6): 1359-72.
-
(2011)
Inflamm Bowel Dis.
, vol.17
, Issue.6
, pp. 1359-1372
-
-
Hirota, S.A.1
Ng, J.2
Lueng, A.3
Khajah, M.4
Parhar, K.5
Li, Y.6
Lam, V.7
Potentier, M.S.8
Ng, K.9
Bawa, M.10
McCafferty, D.M.11
Rioux, K.P.12
Ghosh, S.13
Xavier, R.J.14
Colgan, S.P.15
Tschopp, J.16
Muruve, D.17
McDonald, J.A.18
Beck, P.L.19
-
114
-
-
78049488908
-
IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation
-
Oct 15
-
Zaki MH, Vogel P, Body-Malapel M, Lamkanfi M, Kanneganti TD. IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. J Immunol. 2010 Oct 15; 185 (8): 4912-20.
-
(2010)
J Immunol.
, vol.185
, Issue.8
, pp. 4912-4920
-
-
Zaki, M.H.1
Vogel, P.2
Body-Malapel, M.3
Lamkanfi, M.4
Kanneganti, T.D.5
-
115
-
-
84856957894
-
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
-
Feb 9
-
Henao-Mejia J, Elinav E, Jin C, Hao L, Mehal WZ, Strowig T, Thaiss CA, Kau AL, Eisenbarth SC, Jurczak MJ, Camporez JP, Shulman GI, Gordon JI, Hoffman HM, Flavell RA. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature. 2012 Feb 9; 482 (7384): 179-85.
-
(2012)
Nature.
, vol.482
, Issue.7384
, pp. 179-185
-
-
Henao-Mejia, J.1
Elinav, E.2
Jin, C.3
Hao, L.4
Mehal, W.Z.5
Strowig, T.6
Thaiss, C.A.7
Kau, A.L.8
Eisenbarth, S.C.9
Jurczak, M.J.10
Camporez, J.P.11
Shulman, G.I.12
Gordon, J.I.13
Hoffman, H.M.14
Flavell, R.A.15
-
116
-
-
84868615556
-
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
-
Huber S, Gagliani N, Zenewicz LA, Huber FJ, Bosurgi L, Hu B, Hedl M, Zhang W, O'Connor W Jr, Murphy AJ, Valenzuela DM, Yancopoulos GD, Booth CJ, Cho JH, Ouyang W, Abraham C, Flavell RA. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature. 2012; 491 (7423): 259-63.
-
(2012)
Nature.
, vol.491
, Issue.7423
, pp. 259-263
-
-
Huber, S.1
Gagliani, N.2
Zenewicz, L.A.3
Huber, F.J.4
Bosurgi, L.5
Hu, B.6
Hedl, M.7
Zhang, W.8
O'Connor Jr., W.9
Murphy, A.J.10
Valenzuela, D.M.11
Yancopoulos, G.D.12
Booth, C.J.13
Cho, J.H.14
Ouyang, W.15
Abraham, C.16
Flavell, R.A.17
-
117
-
-
33947497237
-
NALP1 in vitiligoassociated multiple autoimmune disease
-
Jin Y, Mailloux CM, Gowan K, Riccardi SL, LaBerge G, Bennett DC, Fain PR, Spritz RA. NALP1 in vitiligoassociated multiple autoimmune disease. N Engl J Med. 2007; 356 (12): 1216-25.
-
(2007)
N Engl J Med.
, vol.356
, Issue.12
, pp. 1216-1225
-
-
Jin, Y.1
Mailloux, C.M.2
Gowan, K.3
Riccardi, S.L.4
LaBerge, G.5
Bennett, D.C.6
Fain, P.R.7
Spritz, R.A.8
-
118
-
-
30844432876
-
Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization
-
Yu JW, Wu J, Zhang Z, Datta P, Ibrahimi I, Taniguchi S, Sagara J, Fernandes-Alnemri T, Alnemri ES. Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. Cell Death Differ. 2006; 13 (2): 236-49.
-
(2006)
Cell Death Differ.
, vol.13
, Issue.2
, pp. 236-249
-
-
Yu, J.W.1
Wu, J.2
Zhang, Z.3
Datta, P.4
Ibrahimi, I.5
Taniguchi, S.6
Sagara, J.7
Fernandes-Alnemri, T.8
Alnemri, E.S.9
-
119
-
-
77955390094
-
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella
-
Broz P, Newton K, Lamkanfi M, Mariathasan S, Dixit VM, Monack DM. Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. J Exp Med. 2010; 207 (8): 1745-55.
-
(2010)
J Exp Med.
, vol.207
, Issue.8
, pp. 1745-1755
-
-
Broz, P.1
Newton, K.2
Lamkanfi, M.3
Mariathasan, S.4
Dixit, V.M.5
Monack, D.M.6
-
120
-
-
78650210802
-
Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing
-
Broz P, von Moltke J, Jones JW, Vance RE, Monack DM. Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing. Cell Host Microbe. 2010; 8 (6): 471-83.
-
(2010)
Cell Host Microbe.
, vol.8
, Issue.6
, pp. 471-483
-
-
Broz, P.1
von Moltke, J.2
Jones, J.W.3
Vance, R.E.4
Monack, D.M.5
-
121
-
-
0034804347
-
Pyrin N-terminal homology domain-and caspase recruitment domaindependent oligomerization of ASC
-
Masumoto J, Taniguchi S, Sagara J. Pyrin N-terminal homology domain-and caspase recruitment domaindependent oligomerization of ASC. Biochem Biophys Res Commun. 2001; 280 (3): 652-5.
-
(2001)
Biochem Biophys Res Commun.
, vol.280
, Issue.3
, pp. 652-655
-
-
Masumoto, J.1
Taniguchi, S.2
Sagara, J.3
-
122
-
-
12144284412
-
Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC
-
Moriya M, Taniguchi S, Wu P, Liepinsh E, Otting G, Sagara J. Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC. Biochemistry. 2005; 44 (2): 575-83.
-
(2005)
Biochemistry.
, vol.44
, Issue.2
, pp. 575-583
-
-
Moriya, M.1
Taniguchi, S.2
Wu, P.3
Liepinsh, E.4
Otting, G.5
Sagara, J.6
-
123
-
-
0042386425
-
The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition
-
Liepinsh E, Barbals R, Dahl E, Sharipo A, Staub E, Otting G. The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition. J Mol Biol. 2003; 332 (5): 1155-63.
-
(2003)
J Mol Biol.
, vol.332
, Issue.5
, pp. 1155-1163
-
-
Liepinsh, E.1
Barbals, R.2
Dahl, E.3
Sharipo, A.4
Staub, E.5
Otting, G.6
-
124
-
-
84871314266
-
Multiple binding sites on the pyrin domain of ASC protein allow selfassociation and interaction with NLRP3 protein
-
Vajjhala PR, Mirams RE, Hill JM. Multiple binding sites on the pyrin domain of ASC protein allow selfassociation and interaction with NLRP3 protein. J Biol Chem. 2012; 287 (50): 41732-43.
-
(2012)
J Biol Chem.
, vol.287
, Issue.50
, pp. 41732-41743
-
-
Vajjhala, P.R.1
Mirams, R.E.2
Hill, J.M.3
-
125
-
-
84872451259
-
The CARD plays a critical role in ASC foci formation and inflammasome signalling
-
Proell M, Gerlic M, Mace PD, Reed JC, Riedl SJ. The CARD plays a critical role in ASC foci formation and inflammasome signalling. Biochem J. 2013; 449 (3): 613-21.
-
(2013)
Biochem J.
, vol.449
, Issue.3
, pp. 613-621
-
-
Proell, M.1
Gerlic, M.2
Mace, P.D.3
Reed, J.C.4
Riedl, S.J.5
-
126
-
-
73649086203
-
Kinetic properties of ASC protein aggregation in epithelial cells
-
Cheng J, Waite AL, Tkaczyk ER, Ke K, Richards N, Hunt AJ, Gumucio DL. Kinetic properties of ASC protein aggregation in epithelial cells. J Cell Physiol. 2010; 222 (3): 738-47.
-
(2010)
J Cell Physiol.
, vol.222
, Issue.3
, pp. 738-747
-
-
Cheng, J.1
Waite, A.L.2
Tkaczyk, E.R.3
Ke, K.4
Richards, N.5
Hunt, A.J.6
Gumucio, D.L.7
-
127
-
-
58249089097
-
Expression of ASC in renal tissues of familial mediterranean fever patients with amyloidosis: Postulating a role for ASC in AA type amyloid deposition
-
Balci-Peynircioglu B, Waite AL, Schaner P, Taskiran ZE, Richards N, Orhan D, Gucer S, Ozen S, Gumucio D, Yilmaz E. Expression of ASC in renal tissues of familial mediterranean fever patients with amyloidosis: postulating a role for ASC in AA type amyloid deposition. Exp Biol Med (Maywood). 2008; 233 (11): 1324-33.
-
(2008)
Exp Biol Med (Maywood).
, vol.233
, Issue.11
, pp. 1324-1333
-
-
Balci-Peynircioglu, B.1
Waite, A.L.2
Schaner, P.3
Taskiran, Z.E.4
Richards, N.5
Orhan, D.6
Gucer, S.7
Ozen, S.8
Gumucio, D.9
Yilmaz, E.10
-
128
-
-
34547101484
-
Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria
-
Franchi L, Kanneganti TD, Dubyak GR, Nunez G. Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria. J Biol Chem. 2007; 282 (26): 18810-8.
-
(2007)
J Biol Chem.
, vol.282
, Issue.26
, pp. 18810-18818
-
-
Franchi, L.1
Kanneganti, T.D.2
Dubyak, G.R.3
Nunez, G.4
-
129
-
-
0035830853
-
ATP-stimulated release of interleukin (IL)-1beta and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage
-
Mehta VB, Hart J, Wewers MD. ATP-stimulated release of interleukin (IL)-1beta and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage. J Biol Chem. 2001; 276 (6): 3820-6.
-
(2001)
J Biol Chem.
, vol.276
, Issue.6
, pp. 3820-3826
-
-
Mehta, V.B.1
Hart, J.2
Wewers, M.D.3
-
130
-
-
84865355155
-
Tyrosine phosphatase inhibition induces an ASC-dependent pyroptosis
-
Ghonime MG, Shamaa OR, Eldomany RA, Gavrilin MA, Wewers MD. Tyrosine phosphatase inhibition induces an ASC-dependent pyroptosis. Biochem Biophys Res Commun. 2012; 425 (2): 384-9.
-
(2012)
Biochem Biophys Res Commun.
, vol.425
, Issue.2
, pp. 384-389
-
-
Ghonime, M.G.1
Shamaa, O.R.2
Eldomany, R.A.3
Gavrilin, M.A.4
Wewers, M.D.5
-
131
-
-
0038682430
-
The PAAD/PYRIN-only protein POP1/ ASC2 is a modulator of ASC-mediated nuclear-factorkappa B and pro-caspase-1 regulation
-
Stehlik C, Krajewska M, Welsh K, Krajewski S, Godzik A, Reed JC. The PAAD/PYRIN-only protein POP1/ ASC2 is a modulator of ASC-mediated nuclear-factorkappa B and pro-caspase-1 regulation. Biochem J. 2003; 373 (Pt 1): 101-13.
-
(2003)
Biochem J.
, vol.373
, Issue.PART 1
, pp. 101-113
-
-
Stehlik, C.1
Krajewska, M.2
Welsh, K.3
Krajewski, S.4
Godzik, A.5
Reed, J.C.6
-
132
-
-
84887897805
-
Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity
-
Hara H, Tsuchiya K, Kawamura I, Fang R, Hernandez-Cuellar E, Shen Y, Mizuguchi J, Schweighoffer E, Tybulewicz V, Mitsuyama M. Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity. Nat Immunol. 2013; 14 (12): 1247-55.
-
(2013)
Nat Immunol.
, vol.14
, Issue.12
, pp. 1247-1255
-
-
Hara, H.1
Tsuchiya, K.2
Kawamura, I.3
Fang, R.4
Hernandez-Cuellar, E.5
Shen, Y.6
Mizuguchi, J.7
Schweighoffer, E.8
Tybulewicz, V.9
Mitsuyama, M.10
-
134
-
-
84857195479
-
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
-
Shi CS, Shenderov K, Huang NN, Kabat J, Abu-Asab M, Fitzgerald KA, Sher A, Kehrl JH. Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction. Nat Immunol. 2012; 13 (3): 255-63.
-
(2012)
Nat Immunol.
, vol.13
, Issue.3
, pp. 255-263
-
-
Shi, C.S.1
Shenderov, K.2
Huang, N.N.3
Kabat, J.4
Abu-Asab, M.5
Fitzgerald, K.A.6
Sher, A.7
Kehrl, J.H.8
-
135
-
-
84869219269
-
Interactome-wide analysis identifies end-binding protein 1 as a crucial component for the speck-like particle formation of activated absence in melanoma 2 (AIM2) inflammasomes
-
Wang LJ, Hsu CW, Chen CC, Liang Y, Chen LC, Ojcius DM, Tsang NM, Hsueh C, Wu CC, Chang YS. Interactome-wide analysis identifies end-binding protein 1 as a crucial component for the speck-like particle formation of activated absence in melanoma 2 (AIM2) inflammasomes. Mol Cell Proteomics. 2012; 11 (11): 1230-44.
-
(2012)
Mol Cell Proteomics.
, vol.11
, Issue.11
, pp. 1230-1244
-
-
Wang, L.J.1
Hsu, C.W.2
Chen, C.C.3
Liang, Y.4
Chen, L.C.5
Ojcius, D.M.6
Tsang, N.M.7
Hsueh, C.8
Wu, C.C.9
Chang, Y.S.10
-
136
-
-
77953813317
-
Differential splicing of the apoptosisassociated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes
-
Bryan NB, Dorfleutner A, Kramer SJ, Yun C, Rojanasakul Y, Stehlik C. Differential splicing of the apoptosisassociated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes. J Inflamm (Lond). 2010; 7: 23.
-
(2010)
J Inflamm (Lond).
, vol.7
, pp. 23
-
-
Bryan, N.B.1
Dorfleutner, A.2
Kramer, S.J.3
Yun, C.4
Rojanasakul, Y.5
Stehlik, C.6
-
137
-
-
70350006843
-
A splice variant of ASC regulates IL-1β release and aggregates differently from intact ASC
-
Matsushita K, Takeoka M, Sagara J, Itano N, Kurose Y, Nakamura A, Taniguchi S. A splice variant of ASC regulates IL-1β release and aggregates differently from intact ASC. Mediators Inflamm. 2009; 2009: 287387.
-
(2009)
Mediators Inflamm.
, vol.2009
, pp. 287387
-
-
Matsushita, K.1
Takeoka, M.2
Sagara, J.3
Itano, N.4
Kurose, Y.5
Nakamura, A.6
Taniguchi, S.7
-
138
-
-
64849097220
-
Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain
-
Bryan NB, Dorfleutner A, Rojanasakul Y, Stehlik C. Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain. J Immunol. 2009; 182 (5): 3173-82.
-
(2009)
J Immunol.
, vol.182
, Issue.5
, pp. 3173-3182
-
-
Bryan, N.B.1
Dorfleutner, A.2
Rojanasakul, Y.3
Stehlik, C.4
-
139
-
-
80052968438
-
The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization
-
Ippagunta SK, Malireddi RK, Shaw PJ, Neale GA, Walle LV, Green DR, Fukui Y, Lamkanfi M, Kanneganti TD. The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization. Nat Immunol. 2011; 12 (10): 1010-6.
-
(2011)
Nat Immunol.
, vol.12
, Issue.10
, pp. 1010-1016
-
-
Ippagunta, S.K.1
Malireddi, R.K.2
Shaw, P.J.3
Neale, G.A.4
Walle, L.V.5
Green, D.R.6
Fukui, Y.7
Lamkanfi, M.8
Kanneganti, T.D.9
-
140
-
-
84867304098
-
NLRP3 inflammasome activity is negatively controlled by miR-223
-
Bauernfeind F, Rieger A, Schildberg FA, Knolle PA, Schmid-Burgk JL, Hornung V. NLRP3 inflammasome activity is negatively controlled by miR-223. J Immunol. 2012; 189 (8): 4175-81.
-
(2012)
J Immunol.
, vol.189
, Issue.8
, pp. 4175-4181
-
-
Bauernfeind, F.1
Rieger, A.2
Schildberg, F.A.3
Knolle, P.A.4
Schmid-Burgk, J.L.5
Hornung, V.6
-
141
-
-
84867320879
-
Cutting edge: MiR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1βeta production
-
Haneklaus M, Gerlic M, Kurowska-Stolarska M, Rainey AA, Pich D, McInnes IB, Hammerschmidt W, O'Neill LA, Masters SL. Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1βeta production. J Immunol. 2012; 189 (8): 3795-9.
-
(2012)
J Immunol.
, vol.189
, Issue.8
, pp. 3795-3799
-
-
Haneklaus, M.1
Gerlic, M.2
Kurowska-Stolarska, M.3
Rainey, A.A.4
Pich, D.5
McInnes, I.B.6
Hammerschmidt, W.7
O'Neill, L.A.8
Masters, S.L.9
-
142
-
-
84867770402
-
Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation
-
Juliana C, Fernandes-Alnemri T, Kang S, Farias A, Qin F, Alnemri ES. Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation. J Biol Chem. 2012; 287 (43): 36617-22.
-
(2012)
J Biol Chem.
, vol.287
, Issue.43
, pp. 36617-36622
-
-
Juliana, C.1
Fernandes-Alnemri, T.2
Kang, S.3
Farias, A.4
Qin, F.5
Alnemri, E.S.6
-
143
-
-
84873834109
-
Deubiquitinases regulate the activity of caspase-1 and interleukin-1beta secretion via assembly of the inflammasome
-
Lopez-Castejon G, Luheshi NM, Compan V, High S, Whitehead RC, Flitsch S, Kirov A, Prudovsky I, Swanton E, Brough D. Deubiquitinases regulate the activity of caspase-1 and interleukin-1beta secretion via assembly of the inflammasome. J Biol Chem. 2013; 288 (4): 2721-33.
-
(2013)
J Biol Chem.
, vol.288
, Issue.4
, pp. 2721-2733
-
-
Lopez-Castejon, G.1
Luheshi, N.M.2
Compan, V.3
High, S.4
Whitehead, R.C.5
Flitsch, S.6
Kirov, A.7
Prudovsky, I.8
Swanton, E.9
Brough, D.10
-
144
-
-
84872782298
-
Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity
-
Py BF, Kim MS, Vakifahmetoglu-Norberg H, Yuan J. Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity. Mol Cell. 2013; 49 (2): 331-8.
-
(2013)
Mol Cell.
, vol.49
, Issue.2
, pp. 331-338
-
-
Py, B.F.1
Kim, M.S.2
Vakifahmetoglu-Norberg, H.3
Yuan, J.4
-
145
-
-
0042914359
-
Critical role for cathepsin B in mediating caspase-1-dependent interleukin-18 maturation and caspase-1-independent necrosis triggered by the microbial toxin nigericin
-
Hentze H, Lin XY, Choi MS, Porter AG. Critical role for cathepsin B in mediating caspase-1-dependent interleukin-18 maturation and caspase-1-independent necrosis triggered by the microbial toxin nigericin. Cell Death Differ. 2003; 10 (9): 956-68.
-
(2003)
Cell Death Differ.
, vol.10
, Issue.9
, pp. 956-968
-
-
Hentze, H.1
Lin, X.Y.2
Choi, M.S.3
Porter, A.G.4
-
146
-
-
84870514546
-
ATP release and purinergic signaling: A common pathway for particle-mediated inflammasome activation
-
Riteau N, Baron L, Villeret B, Guillou N, Savigny F, Ryffel B, Rassendren F, Le Bert M, Gombault A, Couillin I. ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation. Cell Death Dis. 2012; 3: e403.
-
(2012)
Cell Death Dis.
, vol.3
-
-
Riteau, N.1
Baron, L.2
Villeret, B.3
Guillou, N.4
Savigny, F.5
Ryffel, B.6
Rassendren, F.7
Le Bert, M.8
Gombault, A.9
Couillin, I.10
-
147
-
-
77649179433
-
NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?
-
Tschopp J, Schroder K. NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? Nat Rev Immunol. 2010; 10 (3): 210-5.
-
(2010)
Nat Rev Immunol.
, vol.10
, Issue.3
, pp. 210-215
-
-
Tschopp, J.1
Schroder, K.2
-
148
-
-
84875908991
-
TRPM2 links oxidative stress to NLRP3 inflammasome activation
-
Zhong Z, Zhai Y, Liang S, Mori Y, Han R, Sutterwala FS, Qiao L. TRPM2 links oxidative stress to NLRP3 inflammasome activation. Nat Commun. 2013; 4: 1611.
-
(2013)
Nat Commun.
, vol.4
, pp. 1611
-
-
Zhong, Z.1
Zhai, Y.2
Liang, S.3
Mori, Y.4
Han, R.5
Sutterwala, F.S.6
Qiao, L.7
-
149
-
-
84879596906
-
K+ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter
-
Muñoz-Planillo R, Kuffa P, Martínez-Colón G, Smith BL, Rajendiran TM, Núñez G. K+ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity. 2013; 38 (6): 1142-53.
-
(2013)
Immunity.
, vol.38
, Issue.6
, pp. 1142-1153
-
-
Muñoz-Planillo, R.1
Kuffa, P.2
Martínez-Colón, G.3
Smith, B.L.4
Rajendiran, T.M.5
Núñez, G.6
-
150
-
-
77956574503
-
NOX-free inflammasome activation
-
Latz E. NOX-free inflammasome activation. Blood. 2010; 116 (9): 1393-4.
-
(2010)
Blood.
, vol.116
, Issue.9
, pp. 1393-1394
-
-
Latz, E.1
-
151
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature. 2011; 469 (7329): 221-5.
-
(2011)
Nature.
, vol.469
, Issue.7329
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
152
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, Englert JA, Rabinovitch M, Cernadas M, Kim HP, Fitzgerald KA, Ryter SW, Choi AM. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol. 2011; 12 (3): 222-30.
-
(2011)
Nat Immunol.
, vol.12
, Issue.3
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
Englert, J.A.7
Rabinovitch, M.8
Cernadas, M.9
Kim, H.P.10
Fitzgerald, K.A.11
Ryter, S.W.12
Choi, A.M.13
-
153
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol. 2010; 11 (2): 136-40.
-
(2010)
Nat Immunol.
, vol.11
, Issue.2
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
-
154
-
-
79960542894
-
Cutting edge: Reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
-
Bauernfeind F, Bartok E, Rieger A, Franchi L, Nunez G, Hornung V. Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome. J Immunol. 2011; 187 (2): 613-7.
-
(2011)
J Immunol.
, vol.187
, Issue.2
, pp. 613-617
-
-
Bauernfeind, F.1
Bartok, E.2
Rieger, A.3
Franchi, L.4
Nunez, G.5
Hornung, V.6
-
155
-
-
47849120473
-
Superoxide dismutase 1 regulates caspase-1 and endotoxic shock
-
Meissner F, Molawi K, Zychlinsky A. Superoxide dismutase 1 regulates caspase-1 and endotoxic shock. Nat Immunol. 2008; 9 (8): 866-72.
-
(2008)
Nat Immunol.
, vol.9
, Issue.8
, pp. 866-872
-
-
Meissner, F.1
Molawi, K.2
Zychlinsky, A.3
-
156
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
Petrilli V, Papin S, Dostert C, Mayor A, Martinon F, Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ. 2007; 14 (9): 1583-9.
-
(2007)
Cell Death Differ.
, vol.14
, Issue.9
, pp. 1583-1589
-
-
Petrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
157
-
-
0034082815
-
Interactions and aggregation of apoferritin molecules in solution: Effects of added electrolytes
-
Petsev DN, Thomas BR, Yau S, Vekilov PG. Interactions and aggregation of apoferritin molecules in solution: effects of added electrolytes. Biophys J. 2000; 78 (4): 2060-9.
-
(2000)
Biophys J.
, vol.78
, Issue.4
, pp. 2060-2069
-
-
Petsev, D.N.1
Thomas, B.R.2
Yau, S.3
Vekilov, P.G.4
-
158
-
-
78650926948
-
Sodium overload and water influx activate the NALP3 inflammasome
-
Schorn C, Frey B, Lauber K, Janko C, Strysio M, Keppeler H, Gaipl US, Voll RE, Springer E, Munoz LE, Schett G, Herrmann M. Sodium overload and water influx activate the NALP3 inflammasome. J Biol Chem. 2011; 286 (1): 35-41.
-
(2011)
J Biol Chem.
, vol.286
, Issue.1
, pp. 35-41
-
-
Schorn, C.1
Frey, B.2
Lauber, K.3
Janko, C.4
Strysio, M.5
Keppeler, H.6
Gaipl, U.S.7
Voll, R.E.8
Springer, E.9
Munoz, L.E.10
Schett, G.11
Herrmann, M.12
-
159
-
-
76949094139
-
TRPV2 has a pivotal role in macrophage particle binding and phagocytosis
-
Link TM, Park U, Vonakis BM, Raben DM, Soloski MJ, Caterina MJ. TRPV2 has a pivotal role in macrophage particle binding and phagocytosis. Nat Immunol. 2010; 11 (3): 232-9.
-
(2010)
Nat Immunol.
, vol.11
, Issue.3
, pp. 232-239
-
-
Link, T.M.1
Park, U.2
Vonakis, B.M.3
Raben, D.M.4
Soloski, M.J.5
Caterina, M.J.6
-
160
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, Ramanujan VK, Wolf AJ, Vergnes L, Ojcius DM, Rentsendorj A, Vargas M, Guerrero C, Wang Y, Fitzgerald KA, Underhill DM, Town T, Arditi M. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity. 2012; 36 (3): 401-14.
-
(2012)
Immunity.
, vol.36
, Issue.3
, pp. 401-414
-
-
Shimada, K.1
Crother, T.R.2
Karlin, J.3
Dagvadorj, J.4
Chiba, N.5
Chen, S.6
Ramanujan, V.K.7
Wolf, A.J.8
Vergnes, L.9
Ojcius, D.M.10
Rentsendorj, A.11
Vargas, M.12
Guerrero, C.13
Wang, Y.14
Fitzgerald, K.A.15
Underhill, D.M.16
Town, T.17
Arditi, M.18
-
161
-
-
33750473352
-
Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATPgated P2X7 receptor
-
Pelegrin P, Surprenant A. Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATPgated P2X7 receptor. EMBO J. 2006; 25 (21): 5071-82.
-
(2006)
EMBO J.
, vol.25
, Issue.21
, pp. 5071-5082
-
-
Pelegrin, P.1
Surprenant, A.2
-
162
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
-
Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Kawai T, Tsujimura T, Takeuchi O, Yoshimori T, Akira S. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production. Nature. 2008; 456 (7219): 264-8.
-
(2008)
Nature.
, vol.456
, Issue.7219
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
Uematsu, S.4
Yang, B.G.5
Satoh, T.6
Omori, H.7
Noda, T.8
Yamamoto, N.9
Komatsu, M.10
Tanaka, K.11
Kawai, T.12
Tsujimura, T.13
Takeuchi, O.14
Yoshimori, T.15
Akira, S.16
-
163
-
-
84865427488
-
Mitochondria as sensors and regulators of calcium signalling
-
Rizzuto R, De Stefani D, Raffaello A, Mammucari C. Mitochondria as sensors and regulators of calcium signalling. Nat Rev Mol Cell Biol. 2012; 13 (9): 566-78.
-
(2012)
Nat Rev Mol Cell Biol.
, vol.13
, Issue.9
, pp. 566-578
-
-
Rizzuto, R.1
De Stefani, D.2
Raffaello, A.3
Mammucari, C.4
-
164
-
-
84876567161
-
Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
-
Misawa T, Takahama M, Kozaki T, Lee H, Zou J, Saitoh T, Akira S. Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome. Nat Immunol. 2013; 14 (5): 454-60.
-
(2013)
Nat Immunol.
, vol.14
, Issue.5
, pp. 454-460
-
-
Misawa, T.1
Takahama, M.2
Kozaki, T.3
Lee, H.4
Zou, J.5
Saitoh, T.6
Akira, S.7
-
165
-
-
84876237736
-
The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation
-
Subramanian N, Natarajan K, Clatworthy MR, Wang Z, Germain RN. The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation. Cell. 2013; 153 (2): 348-61.
-
(2013)
Cell.
, vol.153
, Issue.2
, pp. 348-361
-
-
Subramanian, N.1
Natarajan, K.2
Clatworthy, M.R.3
Wang, Z.4
Germain, R.N.5
-
166
-
-
79953176280
-
Autophagy controls IL-1β secretion by targeting pro-IL-1β for degradation
-
Harris J, Hartman M, Roche C, Zeng SG, O'Shea A, Sharp FA, Lambe EM, Creagh EM, Golenbock DT, Tschopp J, Kornfeld H, Fitzgerald KA, Lavelle EC. Autophagy controls IL-1β secretion by targeting pro-IL-1β for degradation. J Biol Chem. 2011; 286 (11): 9587-97.
-
(2011)
J Biol Chem.
, vol.286
, Issue.11
, pp. 9587-9597
-
-
Harris, J.1
Hartman, M.2
Roche, C.3
Zeng, S.G.4
O'Shea, A.5
Sharp, F.A.6
Lambe, E.M.7
Creagh, E.M.8
Golenbock, D.T.9
Tschopp, J.10
Kornfeld, H.11
Fitzgerald, K.A.12
Lavelle, E.C.13
-
167
-
-
82455210868
-
Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β
-
Dupont N, Jiang S, Pilli M, Ornatowski W, Bhattacharya D, Deretic V. Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β. EMBO J. 2011; 30 (23): 4701-11.
-
(2011)
EMBO J.
, vol.30
, Issue.23
, pp. 4701-4711
-
-
Dupont, N.1
Jiang, S.2
Pilli, M.3
Ornatowski, W.4
Bhattacharya, D.5
Deretic, V.6
-
168
-
-
84863978096
-
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
-
Murakami T, Ockinger J, Yu J, Byles V, McColl A, Hofer AM, Horng T. Critical role for calcium mobilization in activation of the NLRP3 inflammasome. Proc Natl Acad Sci U S A. 2012; 109 (28): 11282-7.
-
(2012)
Proc Natl Acad Sci U S A.
, vol.109
, Issue.28
, pp. 11282-11287
-
-
Murakami, T.1
Ockinger, J.2
Yu, J.3
Byles, V.4
McColl, A.5
Hofer, A.M.6
Horng, T.7
-
169
-
-
84870508924
-
The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP
-
Lee GS, Subramanian N, Kim AI, Aksentijevich I, Goldbach-Mansky R, Sacks DB, Germain RN, Kastner DL, Chae JJ. The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature. 2012; 492 (7427): 123-7.
-
(2012)
Nature.
, vol.492
, Issue.7427
, pp. 123-127
-
-
Lee, G.S.1
Subramanian, N.2
Kim, A.I.3
Aksentijevich, I.4
Goldbach-Mansky, R.5
Sacks, D.B.6
Germain, R.N.7
Kastner, D.L.8
Chae, J.J.9
-
170
-
-
84871797522
-
Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors
-
Rossol M, Pierer M, Raulien N, Quandt D, Meusch U, Rothe K, Schubert K, Schoneberg T, Schaefer M, Krugel U, Smajilovic S, Brauner-Osborne H, Baerwald C, Wagner U. Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors. Nat Commun. 2012; 3: 1329.
-
(2012)
Nat Commun.
, vol.3
, pp. 1329
-
-
Rossol, M.1
Pierer, M.2
Raulien, N.3
Quandt, D.4
Meusch, U.5
Rothe, K.6
Schubert, K.7
Schoneberg, T.8
Schaefer, M.9
Krugel, U.10
Smajilovic, S.11
Brauner-Osborne, H.12
Baerwald, C.13
Wagner, U.14
-
171
-
-
84869785875
-
Cutting edge: Nitric oxide inhibits the NLRP3 inflammasome
-
Hernandez-Cuellar E, Tsuchiya K, Hara H, Fang R, Sakai S, Kawamura I, Akira S, Mitsuyama M. Cutting edge: nitric oxide inhibits the NLRP3 inflammasome. J Immunol. 2012; 189 (11): 5113-7.
-
(2012)
J Immunol.
, vol.189
, Issue.11
, pp. 5113-5117
-
-
Hernandez-Cuellar, E.1
Tsuchiya, K.2
Hara, H.3
Fang, R.4
Sakai, S.5
Kawamura, I.6
Akira, S.7
Mitsuyama, M.8
-
172
-
-
84871188736
-
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1β
-
Mishra BB, Rathinam VA, Martens GW, Martinot AJ, Kornfeld H, Fitzgerald KA, Sassetti CM. Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1β. Nat Immunol. 2013; 14 (1): 52-60.
-
(2013)
Nat Immunol.
, vol.14
, Issue.1
, pp. 52-60
-
-
Mishra, B.B.1
Rathinam, V.A.2
Martens, G.W.3
Martinot, A.J.4
Kornfeld, H.5
Fitzgerald, K.A.6
Sassetti, C.M.7
-
173
-
-
84873710963
-
Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock
-
Mao K, Chen S, Chen M, Ma Y, Wang Y, Huang B, He Z, Zeng Y, Hu Y, Sun S, Li J, Wu X, Wang X, Strober W, Chen C, Meng G, Sun B. Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock. Cell Res. 2013; 23 (2): 201-12.
-
(2013)
Cell Res.
, vol.23
, Issue.2
, pp. 201-212
-
-
Mao, K.1
Chen, S.2
Chen, M.3
Ma, Y.4
Wang, Y.5
Huang, B.6
He, Z.7
Zeng, Y.8
Hu, Y.9
Sun, S.10
Li, J.11
Wu, X.12
Wang, X.13
Strober, W.14
Chen, C.15
Meng, G.16
Sun, B.17
-
174
-
-
80455176839
-
Noncanonical inflammasome activation targets caspase-11
-
Kayagaki N, Warming S, Lamkanfi M, Vande Walle L, Louie S, Dong J, Newton K, Qu Y, Liu J, Heldens S, Zhang J, Lee WP, Roose-Girma M, Dixit VM. Noncanonical inflammasome activation targets caspase-11. Nature. 2011; 479 (7371): 117-21.
-
(2011)
Nature.
, vol.479
, Issue.7371
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
Newton, K.7
Qu, Y.8
Liu, J.9
Heldens, S.10
Zhang, J.11
Lee, W.P.12
Roose-Girma, M.13
Dixit, V.M.14
-
175
-
-
84864600268
-
TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria
-
Rathinam VA, Vanaja SK, Waggoner L, Sokolovska A, Becker C, Stuart LM, Leong JM, Fitzgerald KA. TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria. Cell. 2012; 150 (3): 606-19.
-
(2012)
Cell.
, vol.150
, Issue.3
, pp. 606-619
-
-
Rathinam, V.A.1
Vanaja, S.K.2
Waggoner, L.3
Sokolovska, A.4
Becker, C.5
Stuart, L.M.6
Leong, J.M.7
Fitzgerald, K.A.8
-
176
-
-
84883775365
-
Noncanonical inflammasome activation by intracellular LPS independent of TLR4
-
Kayagaki N, Wong MT, Stowe IB, Ramani SR, Gonzalez LC, Akashi-Takamura S, Miyake K, Zhang J, Lee WP, Muszynski A, Forsberg LS, Carlson RW, Dixit VM. Noncanonical inflammasome activation by intracellular LPS independent of TLR4. Science. 2013; 341 (6151): 1246-9.
-
(2013)
Science.
, vol.341
, Issue.6151
, pp. 1246-1249
-
-
Kayagaki, N.1
Wong, M.T.2
Stowe, I.B.3
Ramani, S.R.4
Gonzalez, L.C.5
Akashi-Takamura, S.6
Miyake, K.7
Zhang, J.8
Lee, W.P.9
Muszynski, A.10
Forsberg, L.S.11
Carlson, R.W.12
Dixit, V.M.13
-
177
-
-
84856832054
-
Caspase-4 is required for activation of inflammasomes
-
Sollberger G, Strittmatter GE, Kistowska M, French LE, Beer HD. Caspase-4 is required for activation of inflammasomes. J Immunol. 2012; 188 (4): 1992-2000.
-
(2012)
J Immunol.
, vol.188
, Issue.4
, pp. 1992-2000
-
-
Sollberger, G.1
Strittmatter, G.E.2
Kistowska, M.3
French, L.E.4
Beer, H.D.5
-
178
-
-
84857404572
-
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation
-
Vince JE, Wong WW, Gentle I, Lawlor KE, Allam R, O'Reilly L, Mason K, Gross O, Ma S, Guarda G, Anderton H, Castillo R, Hacker G, Silke J, Tschopp J. Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation. Immunity. 2012; 36 (2): 215-27.
-
(2012)
Immunity.
, vol.36
, Issue.2
, pp. 215-227
-
-
Vince, J.E.1
Wong, W.W.2
Gentle, I.3
Lawlor, K.E.4
Allam, R.5
O'Reilly, L.6
Mason, K.7
Gross, O.8
Ma, S.9
Guarda, G.10
Anderton, H.11
Castillo, R.12
Hacker, G.13
Silke, J.14
Tschopp, J.15
-
179
-
-
84255178199
-
Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome
-
Labbe K, McIntire CR, Doiron K, Leblanc PM, Saleh M. Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome. Immunity. 2011; 35 (6): 897-907.
-
(2011)
Immunity.
, vol.35
, Issue.6
, pp. 897-907
-
-
Labbe, K.1
McIntire, C.R.2
Doiron, K.3
Leblanc, P.M.4
Saleh, M.5
-
180
-
-
84872764927
-
Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome
-
Kang TB, Yang SH, Toth B, Kovalenko A, Wallach D. Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity. 2013; 38 (1): 27-40.
-
(2013)
Immunity.
, vol.38
, Issue.1
, pp. 27-40
-
-
Kang, T.B.1
Yang, S.H.2
Toth, B.3
Kovalenko, A.4
Wallach, D.5
-
181
-
-
79955632319
-
Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a
-
Im SS, Yousef L, Blaschitz C, Liu JZ, Edwards RA, Young SG, Raffatellu M, Osborne TF. Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a. Cell Metab. 2011; 13 (5): 540-9.
-
(2011)
Cell Metab.
, vol.13
, Issue.5
, pp. 540-549
-
-
Im, S.S.1
Yousef, L.2
Blaschitz, C.3
Liu, J.Z.4
Edwards, R.A.5
Young, S.G.6
Raffatellu, M.7
Osborne, T.F.8
-
182
-
-
79251550744
-
Cutting edge: NLRC5-dependent activation of the inflammasome
-
Davis BK, Roberts RA, Huang MT, Willingham SB, Conti BJ, Brickey WJ, Barker BR, Kwan M, Taxman DJ, Accavitti-Loper MA, Duncan JA, Ting JP. Cutting edge: NLRC5-dependent activation of the inflammasome. J Immunol. 2011; 186 (3): 1333-7.
-
(2011)
J Immunol.
, vol.186
, Issue.3
, pp. 1333-1337
-
-
Davis, B.K.1
Roberts, R.A.2
Huang, M.T.3
Willingham, S.B.4
Conti, B.J.5
Brickey, W.J.6
Barker, B.R.7
Kwan, M.8
Taxman, D.J.9
Accavitti-Loper, M.A.10
Duncan, J.A.11
Ting, J.P.12
-
183
-
-
78751495854
-
NLRC5 deficiency does not influence cytokine induction by virus and bacteria infections
-
Kumar H, Pandey S, Zou J, Kumagai Y, Takahashi K, Akira S, Kawai T. NLRC5 deficiency does not influence cytokine induction by virus and bacteria infections. J Immunol. 2011; 186 (2): 994-1000.
-
(2011)
J Immunol.
, vol.186
, Issue.2
, pp. 994-1000
-
-
Kumar, H.1
Pandey, S.2
Zou, J.3
Kumagai, Y.4
Takahashi, K.5
Akira, S.6
Kawai, T.7
-
184
-
-
20444442787
-
PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion
-
Kinoshita T, Wang Y, Hasegawa M, Imamura R, Suda T. PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion. J Biol Chem. 2005; 280 (23): 21720-5.
-
(2005)
J Biol Chem.
, vol.280
, Issue.23
, pp. 21720-21725
-
-
Kinoshita, T.1
Wang, Y.2
Hasegawa, M.3
Imamura, R.4
Suda, T.5
-
185
-
-
2942749999
-
PYNOD, a novel Apaf-1/CED4-like protein is an inhibitor of ASC and caspase-1
-
Wang Y, Hasegawa M, Imamura R, Kinoshita T, Kondo C, Konaka K, Suda T. PYNOD, a novel Apaf-1/CED4-like protein is an inhibitor of ASC and caspase-1. Int Immunol. 2004; 16 (6): 777-86.
-
(2004)
Int Immunol.
, vol.16
, Issue.6
, pp. 777-786
-
-
Wang, Y.1
Hasegawa, M.2
Imamura, R.3
Kinoshita, T.4
Kondo, C.5
Konaka, K.6
Suda, T.7
-
186
-
-
77954721051
-
Antiinflammatory activity of PYNOD and its mechanism in humans and mice
-
Imamura R, Wang Y, Kinoshita T, Suzuki M, Noda T, Sagara J, Taniguchi S, Okamoto H, Suda T. Antiinflammatory activity of PYNOD and its mechanism in humans and mice. J Immunol. 2010; 184 (10): 5874-84.
-
(2010)
J Immunol.
, vol.184
, Issue.10
, pp. 5874-5884
-
-
Imamura, R.1
Wang, Y.2
Kinoshita, T.3
Suzuki, M.4
Noda, T.5
Sagara, J.6
Taniguchi, S.7
Okamoto, H.8
Suda, T.9
-
187
-
-
84879184506
-
Roles of NLRP10 in innate and adaptive immunity
-
Damm A, Lautz K, Kufer TA. Roles of NLRP10 in innate and adaptive immunity. Microbes Infect. 2013; 15 (6-7): 516-23.
-
(2013)
Microbes Infect.
, vol.15
, Issue.6-7
, pp. 516-523
-
-
Damm, A.1
Lautz, K.2
Kufer, T.A.3
-
188
-
-
84863726706
-
Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin-1-Syk and p62/SQSTM1
-
Lee HM, Yuk JM, Kim KH, Jang J, Kang G, Park JB, Son JW, Jo EK. Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin-1-Syk and p62/SQSTM1. Immunol Cell Biol. 2012; 90 (6): 601-10.
-
(2012)
Immunol Cell Biol.
, vol.90
, Issue.6
, pp. 601-610
-
-
Lee, H.M.1
Yuk, J.M.2
Kim, K.H.3
Jang, J.4
Kang, G.5
Park, J.B.6
Son, J.W.7
Jo, E.K.8
-
189
-
-
77954958602
-
Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase
-
Saïd-Sadier N, Padilla E, Langsley G, Ojcius DM. Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase. PLoS One. 2010; 5 (4): e10008.
-
(2010)
PLoS One.
, vol.5
, Issue.4
-
-
Saïd-Sadier, N.1
Padilla, E.2
Langsley, G.3
Ojcius, D.M.4
-
190
-
-
70049101754
-
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases
-
Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, Sutterwala FS, Bohle DS, Descoteaux A, Flavell RA, Olivier M. Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. PLoS Pathog. 2009; 5 (8): e1000559.
-
(2009)
PLoS Pathog.
, vol.5
, Issue.8
-
-
Shio, M.T.1
Eisenbarth, S.C.2
Savaria, M.3
Vinet, A.F.4
Bellemare, M.J.5
Harder, K.W.6
Sutterwala, F.S.7
Bohle, D.S.8
Descoteaux, A.9
Flavell, R.A.10
Olivier, M.11
-
191
-
-
78751700420
-
Tumor suppressor death-associated protein kinase is required for full IL-1β production
-
Chuang YT, Lin YC, Lin KH, Chou TF, Kuo WC, Yang KT, Wu PR, Chen RH, Kimchi A, Lai MZ. Tumor suppressor death-associated protein kinase is required for full IL-1β production. Blood. 2011; 117 (3): 960-70.
-
(2011)
Blood.
, vol.117
, Issue.3
, pp. 960-970
-
-
Chuang, Y.T.1
Lin, Y.C.2
Lin, K.H.3
Chou, T.F.4
Kuo, W.C.5
Yang, K.T.6
Wu, P.R.7
Chen, R.H.8
Kimchi, A.9
Lai, M.Z.10
-
192
-
-
78649819208
-
Chemical probing reveals insights into the signaling mechanism of inflammasome activation
-
Gong YN, Wang X, Wang J, Yang Z, Li S, Yang J, Liu L, Lei X, Shao F. Chemical probing reveals insights into the signaling mechanism of inflammasome activation. Cell Res. 2010; 20 (12): 1289-305.
-
(2010)
Cell Res.
, vol.20
, Issue.12
, pp. 1289-1305
-
-
Gong, Y.N.1
Wang, X.2
Wang, J.3
Yang, Z.4
Li, S.5
Yang, J.6
Liu, L.7
Lei, X.8
Shao, F.9
-
193
-
-
84865511926
-
Novel role of PKR in inflammasome activation and HMGB1 release
-
Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundback P, Valdes-Ferrer SI, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting JP, Wang H, Andersson U, Antoine DJ, Chavan SS, Hotamisligil GS, Tracey KJ. Novel role of PKR in inflammasome activation and HMGB1 release. Nature. 2012; 488 (7413): 670-4.
-
(2012)
Nature.
, vol.488
, Issue.7413
, pp. 670-674
-
-
Lu, B.1
Nakamura, T.2
Inouye, K.3
Li, J.4
Tang, Y.5
Lundback, P.6
Valdes-Ferrer, S.I.7
Olofsson, P.S.8
Kalb, T.9
Roth, J.10
Zou, Y.11
Erlandsson-Harris, H.12
Yang, H.13
Ting, J.P.14
Wang, H.15
Andersson, U.16
Antoine, D.J.17
Chavan, S.S.18
Hotamisligil, G.S.19
Tracey, K.J.20
more..
-
194
-
-
84876872146
-
The protein kinase PKR is critical for LPS-induced iNOS production but dispensable for inflammasome activation in macrophages
-
He Y, Franchi L, Nunez G. The protein kinase PKR is critical for LPS-induced iNOS production but dispensable for inflammasome activation in macrophages. Eur J Immunol. 2013; 43 (5): 1147-52.
-
(2013)
Eur J Immunol.
, vol.43
, Issue.5
, pp. 1147-1152
-
-
He, Y.1
Franchi, L.2
Nunez, G.3
-
195
-
-
84879098248
-
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis
-
Hett EC, Slater LH, Mark KG, Kawate T, Monks BG, Stutz A, Latz E, Hung DT. Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis. Nat Chem Biol. 2013; 9 (6): 398-405.
-
(2013)
Nat Chem Biol.
, vol.9
, Issue.6
, pp. 398-405
-
-
Hett, E.C.1
Slater, L.H.2
Mark, K.G.3
Kawate, T.4
Monks, B.G.5
Stutz, A.6
Latz, E.7
Hung, D.T.8
-
196
-
-
84861204618
-
CEACAM1 negatively regulates IL-1β production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complex
-
Lu R, Pan H, Shively JE. CEACAM1 negatively regulates IL-1β production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complex. PLoS Pathog. 2012; 8 (4): e1002597.
-
(2012)
PLoS Pathog.
, vol.8
, Issue.4
-
-
Lu, R.1
Pan, H.2
Shively, J.E.3
-
197
-
-
79951740151
-
Type I interferon inhibits interleukin-1 production and inflammasome activation
-
Guarda G, Braun M, Staehli F, Tardivel A, Mattmann C, Forster I, Farlik M, Decker T, Du Pasquier RA, Romero P, Tschopp J. Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity. 2011; 34 (2): 213-23.
-
(2011)
Immunity.
, vol.34
, Issue.2
, pp. 213-223
-
-
Guarda, G.1
Braun, M.2
Staehli, F.3
Tardivel, A.4
Mattmann, C.5
Forster, I.6
Farlik, M.7
Decker, T.8
Du Pasquier, R.A.9
Romero, P.10
Tschopp, J.11
-
198
-
-
84861473687
-
Interferon-beta therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome
-
Inoue M, Williams KL, Oliver T, Vandenabeele P, Rajan JV, Miao EA, Shinohara ML. Interferon-beta therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome. Sci Signal. 2012; 5 (225): ra38.
-
(2012)
Sci Signal.
, vol.5
, Issue.225
-
-
Inoue, M.1
Williams, K.L.2
Oliver, T.3
Vandenabeele, P.4
Rajan, J.V.5
Miao, E.A.6
Shinohara, M.L.7
-
199
-
-
84860225554
-
GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals
-
Shenoy AR, Wellington DA, Kumar P, Kassa H, Booth CJ, Cresswell P, MacMicking JD. GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals. Science. 2012; 336 (6080): 481-5.
-
(2012)
Science.
, vol.336
, Issue.6080
, pp. 481-485
-
-
Shenoy, A.R.1
Wellington, D.A.2
Kumar, P.3
Kassa, H.4
Booth, C.J.5
Cresswell, P.6
McMicking, J.D.7
-
200
-
-
84880745984
-
The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome
-
Mitoma H, Hanabuchi S, Kim T, Bao M, Zhang Z, Sugimoto N, Liu YJ. The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome. Immunity. 2013; 39 (1): 123-35.
-
(2013)
Immunity.
, vol.39
, Issue.1
, pp. 123-135
-
-
Mitoma, H.1
Hanabuchi, S.2
Kim, T.3
Bao, M.4
Zhang, Z.5
Sugimoto, N.6
Liu, Y.J.7
-
201
-
-
78650636576
-
Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production
-
Hu Y, Mao K, Zeng Y, Chen S, Tao Z, Yang C, Sun S, Wu X, Meng G, Sun B. Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production. J Immunol. 2010; 185 (12): 7699-705.
-
(2010)
J Immunol.
, vol.185
, Issue.12
, pp. 7699-7705
-
-
Hu, Y.1
Mao, K.2
Zeng, Y.3
Chen, S.4
Tao, Z.5
Yang, C.6
Sun, S.7
Wu, X.8
Meng, G.9
Sun, B.10
-
202
-
-
84879582536
-
Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation
-
Yan Y, Jiang W, Spinetti T, Tardivel A, Castillo R, Bourquin C, Guarda G, Tian Z, Tschopp J, Zhou R. Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation. Immunity. 2013; 38 (6): 1154-63.
-
(2013)
Immunity.
, vol.38
, Issue.6
, pp. 1154-1163
-
-
Yan, Y.1
Jiang, W.2
Spinetti, T.3
Tardivel, A.4
Castillo, R.5
Bourquin, C.6
Guarda, G.7
Tian, Z.8
Tschopp, J.9
Zhou, R.10
-
203
-
-
84872031643
-
Chitinase 3-like-1 promotes Streptococcus pneumoniae killing and augments host tolerance to lung antibacterial responses
-
Dela Cruz CS, Liu W, He CH, Jacoby A, Gornitzky A, Ma B, Flavell R, Lee CG, Elias JA. Chitinase 3-like-1 promotes Streptococcus pneumoniae killing and augments host tolerance to lung antibacterial responses. Cell Host Microbe. 2012; 12 (1): 34-46.
-
(2012)
Cell Host Microbe.
, vol.12
, Issue.1
, pp. 34-46
-
-
Dela Cruz, C.S.1
Liu, W.2
He, C.H.3
Jacoby, A.4
Gornitzky, A.5
Ma, B.6
Flavell, R.7
Lee, C.G.8
Elias, J.A.9
-
204
-
-
84883265444
-
Chitinase 3-like 1 regulates cellular and tissue responses via IL-13 receptor α2
-
He CH, Lee CG, Dela Cruz CS, Lee CM, Zhou Y, Ahangari F, Ma B, Herzog EL, Rosenberg SA, Li Y, Nour AM, Parikh CR, Schmidt I, Modis Y, Cantley L, Elias JA. Chitinase 3-like 1 regulates cellular and tissue responses via IL-13 receptor α2. Cell Rep. 2013; 4 (4): 830-41.
-
(2013)
Cell Rep.
, vol.4
, Issue.4
, pp. 830-841
-
-
He, C.H.1
Lee, C.G.2
Dela Cruz, C.S.3
Lee, C.M.4
Zhou, Y.5
Ahangari, F.6
Ma, B.7
Herzog, E.L.8
Rosenberg, S.A.9
Li, Y.10
Nour, A.M.11
Parikh, C.R.12
Schmidt, I.13
Modis, Y.14
Cantley, L.15
Elias, J.A.16
-
205
-
-
34247265509
-
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses
-
Mayor A, Martinon F, De Smedt T, Petrilli V, Tschopp J. A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses. Nat Immunol. 2007; 8 (5): 497-503.
-
(2007)
Nat Immunol.
, vol.8
, Issue.5
, pp. 497-503
-
-
Mayor, A.1
Martinon, F.2
De Smedt, T.3
Petrilli, V.4
Tschopp, J.5
-
206
-
-
79959732295
-
Nrf2 is essential for cholesterol crystalinduced inflammasome activation and exacerbation of atherosclerosis
-
Freigang S, Ampenberger F, Spohn G, Heer S, Shamshiev AT, Kisielow J, Hersberger M, Yamamoto M, Bachmann MF, Kopf M. Nrf2 is essential for cholesterol crystalinduced inflammasome activation and exacerbation of atherosclerosis. Eur J Immunol. 2011; 41 (7): 2040-51.
-
(2011)
Eur J Immunol.
, vol.41
, Issue.7
, pp. 2040-2051
-
-
Freigang, S.1
Ampenberger, F.2
Spohn, G.3
Heer, S.4
Shamshiev, A.T.5
Kisielow, J.6
Hersberger, M.7
Yamamoto, M.8
Bachmann, M.F.9
Kopf, M.10
-
207
-
-
67650421494
-
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes
-
Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature. 2009; 460 (7252): 269-73.
-
(2009)
Nature.
, vol.460
, Issue.7252
, pp. 269-273
-
-
Guarda, G.1
Dostert, C.2
Staehli, F.3
Cabalzar, K.4
Castillo, R.5
Tardivel, A.6
Schneider, P.7
Tschopp, J.8
-
208
-
-
84877692253
-
Structure of the AIM2 pyrin domain provides insights into the mechanisms of AIM2 autoinhibition and inflammasome assembly
-
Jin T, Perry A, Smith PT, Jiang J, Xiao TS. Structure of the AIM2 pyrin domain provides insights into the mechanisms of AIM2 autoinhibition and inflammasome assembly. J Biol Chem. 2013; 288 (19): 13225-35.
-
(2013)
J Biol Chem.
, vol.288
, Issue.19
, pp. 13225-13235
-
-
Jin, T.1
Perry, A.2
Smith, P.T.3
Jiang, J.4
Xiao, T.S.5
-
209
-
-
77951263260
-
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
-
Fernandes-Alnemri T, Yu JW, Juliana C, Solorzano L, Kang S, Wu J, Datta P, McCormick M, Huang L, McDermott E, Eisenlohr L, Landel CP, Alnemri ES. The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat Immunol. 2010; 11 (5): 385-93.
-
(2010)
Nat Immunol.
, vol.11
, Issue.5
, pp. 385-393
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Juliana, C.3
Solorzano, L.4
Kang, S.5
Wu, J.6
Datta, P.7
McCormick, M.8
Huang, L.9
McDermott, E.10
Eisenlohr, L.11
Landel, C.P.12
Alnemri, E.S.13
-
210
-
-
77953116282
-
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
-
Jones JW, Kayagaki N, Broz P, Henry T, Newton K, O'Rourke K, Chan S, Dong J, Qu Y, Roose-Girma M, Dixit VM, Monack DM. Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. Proc Natl Acad Sci U S A. 2010; 107 (21): 9771-6.
-
(2010)
Proc Natl Acad Sci U S A.
, vol.107
, Issue.21
, pp. 9771-9776
-
-
Jones, J.W.1
Kayagaki, N.2
Broz, P.3
Henry, T.4
Newton, K.5
O'Rourke, K.6
Chan, S.7
Dong, J.8
Qu, Y.9
Roose-Girma, M.10
Dixit, V.M.11
Monack, D.M.12
-
211
-
-
84880818953
-
Molecular mechanism for p202-mediated specific inhibition of AIM2 inflammasome activation
-
Yin Q, Sester DP, Tian Y, Hsiao YS, Lu A, Cridland JA, Sagulenko V, Thygesen SJ, Choubey D, Hornung V, Walz T, Stacey KJ, Wu H. Molecular mechanism for p202-mediated specific inhibition of AIM2 inflammasome activation. Cell Rep. 2013; 4 (2): 327-39.
-
(2013)
Cell Rep.
, vol.4
, Issue.2
, pp. 327-339
-
-
Yin, Q.1
Sester, D.P.2
Tian, Y.3
Hsiao, Y.S.4
Lu, A.5
Cridland, J.A.6
Sagulenko, V.7
Thygesen, S.J.8
Choubey, D.9
Hornung, V.10
Walz, T.11
Stacey, K.J.12
Wu, H.13
-
212
-
-
79959564985
-
Aim2 deficiency in mice suppresses the expression of the inhibitory Fcgamma receptor (FcgammaRIIB) through the induction of the IFN-inducible p202, a lupus susceptibility protein
-
Panchanathan R, Shen H, Duan X, Rathinam VA, Erickson LD, Fitzgerald KA, Choubey D. Aim2 deficiency in mice suppresses the expression of the inhibitory Fcgamma receptor (FcgammaRIIB) through the induction of the IFN-inducible p202, a lupus susceptibility protein. J Immunol. 2011; 186 (12): 6762-70.
-
(2011)
J Immunol.
, vol.186
, Issue.12
, pp. 6762-6770
-
-
Panchanathan, R.1
Shen, H.2
Duan, X.3
Rathinam, V.A.4
Erickson, L.D.5
Fitzgerald, K.A.6
Choubey, D.7
-
213
-
-
80055045773
-
IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes
-
Veeranki S, Duan X, Panchanathan R, Liu H, Choubey D. IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes. PLoS One. 2011; 6 (10): e27040.
-
(2011)
PLoS One.
, vol.6
, Issue.10
-
-
Veeranki, S.1
Duan, X.2
Panchanathan, R.3
Liu, H.4
Choubey, D.5
-
214
-
-
52549099416
-
Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin
-
Lightfield KL, Persson J, Brubaker SW, Witte CE, von Moltke J, Dunipace EA, Henry T, Sun YH, Cado D, Dietrich WF, Monack DM, Tsolis RM, Vance RE. Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin. Nat Immunol. 2008; 9 (10): 1171-8.
-
(2008)
Nat Immunol.
, vol.9
, Issue.10
, pp. 1171-1178
-
-
Lightfield, K.L.1
Persson, J.2
Brubaker, S.W.3
Witte, C.E.4
von Moltke, J.5
Dunipace, E.A.6
Henry, T.7
Sun, Y.H.8
Cado, D.9
Dietrich, W.F.10
Monack, D.M.11
Tsolis, R.M.12
Vance, R.E.13
-
215
-
-
84869044838
-
Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N-and C-terminal regions of flagellin
-
Halff EF, Diebolder CA, Versteeg M, Schouten A, Brondijk TH, Huizinga EG. Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N-and C-terminal regions of flagellin. J Biol Chem. 2012; 287 (46): 38460-72.
-
(2012)
J Biol Chem.
, vol.287
, Issue.46
, pp. 38460-38472
-
-
Halff, E.F.1
Diebolder, C.A.2
Versteeg, M.3
Schouten, A.4
Brondijk, T.H.5
Huizinga, E.G.6
-
216
-
-
79953315378
-
Differential requirements for NAIP5 in activation of the NLRC4 inflammasome
-
Lightfield KL, Persson J, Trinidad NJ, Brubaker SW, Kofoed EM, Sauer JD, Dunipace EA, Warren SE, Miao EA, Vance RE. Differential requirements for NAIP5 in activation of the NLRC4 inflammasome. Infect Immun. 2011; 79 (4): 1606-14.
-
(2011)
Infect Immun.
, vol.79
, Issue.4
, pp. 1606-1614
-
-
Lightfield, K.L.1
Persson, J.2
Trinidad, N.J.3
Brubaker, S.W.4
Kofoed, E.M.5
Sauer, J.D.6
Dunipace, E.A.7
Warren, S.E.8
Miao, E.A.9
Vance, R.E.10
-
217
-
-
80053379974
-
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
-
Kofoed EM, Vance RE. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature. 2011; 477 (7366): 592-5.
-
(2011)
Nature.
, vol.477
, Issue.7366
, pp. 592-595
-
-
Kofoed, E.M.1
Vance, R.E.2
-
218
-
-
84867861468
-
Phosphorylation of NLRC4 is critical for inflammasome activation
-
Qu Y, Misaghi S, Izrael-Tomasevic A, Newton K, Gilmour LL, Lamkanfi M, Louie S, Kayagaki N, Liu J, Komuves L, Cupp JE, Arnott D, Monack D, Dixit VM. Phosphorylation of NLRC4 is critical for inflammasome activation. Nature. 2012; 490 (7421): 539-42.
-
(2012)
Nature.
, vol.490
, Issue.7421
, pp. 539-542
-
-
Qu, Y.1
Misaghi, S.2
Izrael-Tomasevic, A.3
Newton, K.4
Gilmour, L.L.5
Lamkanfi, M.6
Louie, S.7
Kayagaki, N.8
Liu, J.9
Komuves, L.10
Cupp, J.E.11
Arnott, D.12
Monack, D.13
Dixit, V.M.14
-
219
-
-
84861215715
-
Proteolytic processing of Nlrp1b is required for inflammasome activity
-
Frew BC, Joag VR, Mogridge J. Proteolytic processing of Nlrp1b is required for inflammasome activity. PLoS Pathog. 2012; 8 (4): e1002659.
-
(2012)
PLoS Pathog.
, vol.8
, Issue.4
-
-
Frew, B.C.1
Joag, V.R.2
Mogridge, J.3
-
220
-
-
84864110446
-
Autolytic proteolysis within the function to find domain (FIIND) is required for NLRP1 inflammasome activity
-
Finger JN, Lich JD, Dare LC, Cook MN, Brown KK, Duraiswami C, Bertin J, Gough PJ. Autolytic proteolysis within the function to find domain (FIIND) is required for NLRP1 inflammasome activity. J Biol Chem. 2012; 287 (30): 25030-7.
-
(2012)
J Biol Chem.
, vol.287
, Issue.30
, pp. 25030-25037
-
-
Finger, J.N.1
Lich, J.D.2
Dare, L.C.3
Cook, M.N.4
Brown, K.K.5
Duraiswami, C.6
Bertin, J.7
Gough, P.J.8
-
221
-
-
79960450059
-
Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage
-
Ali SR, Timmer AM, Bilgrami S, Park EJ, Eckmann L, Nizet V, Karin M. Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage. Immunity. 2011; 35 (1): 34-44.
-
(2011)
Immunity.
, vol.35
, Issue.1
, pp. 34-44
-
-
Ali, S.R.1
Timmer, A.M.2
Bilgrami, S.3
Park, E.J.4
Eckmann, L.5
Nizet, V.6
Karin, M.7
-
222
-
-
38049119726
-
Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome
-
Wickliffe KE, Leppla SH, Moayeri M. Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome. Cell Microbiol. 2008; 10 (2): 332-43.
-
(2008)
Cell Microbiol.
, vol.10
, Issue.2
, pp. 332-343
-
-
Wickliffe, K.E.1
Leppla, S.H.2
Moayeri, M.3
-
223
-
-
43449092551
-
Killing of macrophages by anthrax lethal toxin: Involvement of the N-end rule pathway
-
Wickliffe KE, Leppla SH, Moayeri M. Killing of macrophages by anthrax lethal toxin: involvement of the N-end rule pathway. Cell Microbiol. 2008; 10 (6): 1352-62.
-
(2008)
Cell Microbiol.
, vol.10
, Issue.6
, pp. 1352-1362
-
-
Wickliffe, K.E.1
Leppla, S.H.2
Moayeri, M.3
-
224
-
-
84869073837
-
Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages
-
Hellmich KA, Levinsohn JL, Fattah R, Newman ZL, Maier N, Sastalla I, Liu S, Leppla SH, Moayeri M. Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages. PLoS One. 2012; 7 (11): e49741.
-
(2012)
PLoS One.
, vol.7
, Issue.11
-
-
Hellmich, K.A.1
Levinsohn, J.L.2
Fattah, R.3
Newman, Z.L.4
Maier, N.5
Sastalla, I.6
Liu, S.7
Leppla, S.H.8
Moayeri, M.9
-
225
-
-
84879508269
-
Direct proteolytic cleavage of NLRP1B is necessary and sufficient for inflammasome activation by anthrax lethal factor
-
Chavarría-Smith J, Vance RE. Direct proteolytic cleavage of NLRP1B is necessary and sufficient for inflammasome activation by anthrax lethal factor. PLoS Pathog. 2013; 9 (6): e1003452.
-
(2013)
PLoS Pathog.
, vol.9
, Issue.6
-
-
Chavarría-Smith, J.1
Vance, R.E.2
-
226
-
-
62449101446
-
Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages
-
Nour AM, Yeung YG, Santambrogio L, Boyden ED, Stanley ER, Brojatsch J. Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages. Infect Immun. 2009; 77 (3): 1262-71.
-
(2009)
Infect Immun.
, vol.77
, Issue.3
, pp. 1262-1271
-
-
Nour, A.M.1
Yeung, Y.G.2
Santambrogio, L.3
Boyden, E.D.4
Stanley, E.R.5
Brojatsch, J.6
-
227
-
-
84873041407
-
Activation of the Nlrp1b inflammasome by reduction of cytosolic ATP
-
Liao KC, Mogridge J. Activation of the Nlrp1b inflammasome by reduction of cytosolic ATP. Infect Immun. 2013; 81 (2): 570-9.
-
(2013)
Infect Immun.
, vol.81
, Issue.2
, pp. 570-579
-
-
Liao, K.C.1
Mogridge, J.2
-
228
-
-
33947717153
-
Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1
-
Bruey JM, Bruey-Sedano N, Luciano F, Zhai D, Balpai R, Xu C, Kress CL, Bailly-Maitre B, Li X, Osterman A, Matsuzawa S, Terskikh AV, Faustin B, Reed JC. Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1. Cell. 2007; 129 (1): 45-56.
-
(2007)
Cell.
, vol.129
, Issue.1
, pp. 45-56
-
-
Bruey, J.M.1
Bruey-Sedano, N.2
Luciano, F.3
Zhai, D.4
Balpai, R.5
Xu, C.6
Kress, C.L.7
Bailly-Maitre, B.8
Li, X.9
Osterman, A.10
Matsuzawa, S.11
Terskikh, A.V.12
Faustin, B.13
Reed, J.C.14
-
229
-
-
0035860780
-
Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing
-
Lee SH, Stehlik C, Reed JC. Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing. J Biol Chem. 2001; 276 (37): 34495-500.
-
(2001)
J Biol Chem.
, vol.276
, Issue.37
, pp. 34495-34500
-
-
Lee, S.H.1
Stehlik, C.2
Reed, J.C.3
-
230
-
-
40049108218
-
COPs and POPs: Modulators of inflammasome activity
-
Stehlik C, Dorfleutner A. COPs and POPs: modulators of inflammasome activity. J Immunol. 2007; 179 (12): 7993-8.
-
(2007)
J Immunol.
, vol.179
, Issue.12
, pp. 7993-7998
-
-
Stehlik, C.1
Dorfleutner, A.2
-
231
-
-
0034730325
-
ICEBERG: A novel inhibitor of interleukin-1beta generation
-
Humke EW, Shriver SK, Starovasnik MA, Fairbrother WJ, Dixit VM. ICEBERG: a novel inhibitor of interleukin-1beta generation. Cell. 2000; 103 (1): 99-111.
-
(2000)
Cell.
, vol.103
, Issue.1
, pp. 99-111
-
-
Humke, E.W.1
Shriver, S.K.2
Starovasnik, M.A.3
Fairbrother, W.J.4
Dixit, V.M.5
-
232
-
-
10644270650
-
INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation
-
Lamkanfi M, Denecker G, Kalai M, D'Hondt K, Meeus A, Declercq W, Saelens X, Vandenabeele P. INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation. J Biol Chem. 2004; 279 (50): 51729-38.
-
(2004)
J Biol Chem.
, vol.279
, Issue.50
, pp. 51729-51738
-
-
Lamkanfi, M.1
Denecker, G.2
Kalai, M.3
D'Hondt, K.4
Meeus, A.5
Declercq, W.6
Saelens, X.7
Vandenabeele, P.8
-
233
-
-
0034743434
-
Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins
-
Druilhe A, Srinivasula SM, Razmara M, Ahmad M, Alnemri ES. Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins. Cell Death Differ. 2001; 8 (6): 649-57.
-
(2001)
Cell Death Differ.
, vol.8
, Issue.6
, pp. 649-657
-
-
Druilhe, A.1
Srinivasula, S.M.2
Razmara, M.3
Ahmad, M.4
Alnemri, E.S.5
-
234
-
-
33644772156
-
A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways
-
Rosenstiel P, Huse K, Till A, Hampe J, Hellmig S, Sina C, Billmann S, von Kampen O, Waetzig GH, Platzer M, Seegert D, Schreiber S. A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways. Proc Natl Acad Sci U S A. 2006; 103 (9): 3280-5.
-
(2006)
Proc Natl Acad Sci U S A.
, vol.103
, Issue.9
, pp. 3280-3285
-
-
Rosenstiel, P.1
Huse, K.2
Till, A.3
Hampe, J.4
Hellmig, S.5
Sina, C.6
Billmann, S.7
von Kampen, O.8
Waetzig, G.H.9
Platzer, M.10
Seegert, D.11
Schreiber, S.12
-
235
-
-
0037134457
-
CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis
-
Razmara M, Srinivasula SM, Wang L, Poyet JL, Geddes BJ, DiStefano PS, Bertin J, Alnemri ES. CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis. J Biol Chem. 2002; 277 (16): 13952-8.
-
(2002)
J Biol Chem.
, vol.277
, Issue.16
, pp. 13952-13958
-
-
Razmara, M.1
Srinivasula, S.M.2
Wang, L.3
Poyet, J.L.4
Geddes, B.J.5
DiStefano, P.S.6
Bertin, J.7
Alnemri, E.S.8
-
236
-
-
0035941220
-
CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways
-
Bouchier-Hayes L, Conroy H, Egan H, Adrain C, Creagh EM, MacFarlane M, Martin SJ. CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways. J Biol Chem. 2001; 276 (47): 44069-77.
-
(2001)
J Biol Chem.
, vol.276
, Issue.47
, pp. 44069-44077
-
-
Bouchier-Hayes, L.1
Conroy, H.2
Egan, H.3
Adrain, C.4
Creagh, E.M.5
McFarlane, M.6
Martin, S.J.7
-
237
-
-
33646175602
-
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice
-
Saleh M, Mathison JC, Wolinski MK, Bensinger SJ, Fitzgerald P, Droin N, Ulevitch RJ, Green DR, Nicholson DW. Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. Nature. 2006; 440 (7087): 1064-8.
-
(2006)
Nature.
, vol.440
, Issue.7087
, pp. 1064-1068
-
-
Saleh, M.1
Mathison, J.C.2
Wolinski, M.K.3
Bensinger, S.J.4
Fitzgerald, P.5
Droin, N.6
Ulevitch, R.J.7
Green, D.R.8
Nicholson, D.W.9
-
238
-
-
2342457148
-
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms
-
Saleh M, Vaillancourt JP, Graham RK, Huyck M, Srinivasula SM, Alnemri ES, Steinberg MH, Nolan V, Baldwin CT, Hotchkiss RS, Buchman TG, Zehnbauer BA, Hayden MR, Farrer LA, Roy S, Nicholson DW. Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature. 2004; 429 (6987): 75-9.
-
(2004)
Nature.
, vol.429
, Issue.6987
, pp. 75-79
-
-
Saleh, M.1
Vaillancourt, J.P.2
Graham, R.K.3
Huyck, M.4
Srinivasula, S.M.5
Alnemri, E.S.6
Steinberg, M.H.7
Nolan, V.8
Baldwin, C.T.9
Hotchkiss, R.S.10
Buchman, T.G.11
Zehnbauer, B.A.12
Hayden, M.R.13
Farrer, L.A.14
Roy, S.15
Nicholson, D.W.16
-
239
-
-
0037349294
-
Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis
-
Chae JJ, Komarow HD, Cheng J, Wood G, Raben N, Liu PP, Kastner DL. Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. Mol Cell. 2003; 11 (3): 591-604.
-
(2003)
Mol Cell.
, vol.11
, Issue.3
, pp. 591-604
-
-
Chae, J.J.1
Komarow, H.D.2
Cheng, J.3
Wood, G.4
Raben, N.5
Liu, P.P.6
Kastner, D.L.7
-
240
-
-
34547138176
-
The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing
-
Papin S, Cuenin S, Agostini L, Martinon F, Werner S, Beer HD, Grutter C, Grutter M, Tschopp J. The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing. Cell Death Differ. 2007; 14 (8): 1457-66.
-
(2007)
Cell Death Differ.
, vol.14
, Issue.8
, pp. 1457-1466
-
-
Papin, S.1
Cuenin, S.2
Agostini, L.3
Martinon, F.4
Werner, S.5
Beer, H.D.6
Grutter, C.7
Grutter, M.8
Tschopp, J.9
-
241
-
-
33745631232
-
The B30. 2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production
-
Chae JJ, Wood G, Masters SL, Richard K, Park G, Smith BJ, Kastner DL. The B30. 2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production. Proc Natl Acad Sci U S A. 2006; 103 (26): 9982-7.
-
(2006)
Proc Natl Acad Sci U S A.
, vol.103
, Issue.26
, pp. 9982-9987
-
-
Chae, J.J.1
Wood, G.2
Masters, S.L.3
Richard, K.4
Park, G.5
Smith, B.J.6
Kastner, D.L.7
-
242
-
-
47249095449
-
Mapping of POP1-binding site on pyrin domain of ASC
-
Srimathi T, Robbins SL, Dubas RL, Chang H, Cheng H, Roder H, Park YC. Mapping of POP1-binding site on pyrin domain of ASC. J Biol Chem. 2008; 283 (22): 15390-8.
-
(2008)
J Biol Chem.
, vol.283
, Issue.22
, pp. 15390-15398
-
-
Srimathi, T.1
Robbins, S.L.2
Dubas, R.L.3
Chang, H.4
Cheng, H.5
Roder, H.6
Park, Y.C.7
-
243
-
-
79952087638
-
Recent evolution of the NF-kappaB and inflammasome regulating protein POP2 in primates
-
Atianand MK, Fuchs T, Harton JA. Recent evolution of the NF-kappaB and inflammasome regulating protein POP2 in primates. BMC Evol Biol. 2011; 11: 56.
-
(2011)
BMC Evol Biol.
, vol.11
, pp. 56
-
-
Atianand, M.K.1
Fuchs, T.2
Harton, J.A.3
-
244
-
-
81755171449
-
Uncoupling of Pyrinonly protein 2 (POP2)-mediated dual regulation of NF-kappaB and the inflammasome
-
Atianand MK, Harton JA. Uncoupling of Pyrinonly protein 2 (POP2)-mediated dual regulation of NF-kappaB and the inflammasome. J Biol Chem. 2011; 286 (47): 40536-47.
-
(2011)
J Biol Chem.
, vol.286
, Issue.47
, pp. 40536-40547
-
-
Atianand, M.K.1
Harton, J.A.2
-
245
-
-
84870606823
-
Cytosolic, autocrine alpha-1 proteinase inhibitor (A1PI) inhibits caspase-1 and blocks IL-1β dependent cytokine release in monocytes
-
Wang Y, He Y, Abraham B, Rouhani FN, Brantly ML, Scott DE, Reed JL. Cytosolic, autocrine alpha-1 proteinase inhibitor (A1PI) inhibits caspase-1 and blocks IL-1β dependent cytokine release in monocytes. PLoS One. 2012; 7 (11): e51078.
-
(2012)
PLoS One.
, vol.7
, Issue.11
-
-
Wang, Y.1
He, Y.2
Abraham, B.3
Rouhani, F.N.4
Brantly, M.L.5
Scott, D.E.6
Reed, J.L.7
-
246
-
-
79959516887
-
Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury
-
Toldo S, Seropian IM, Mezzaroma E, Van Tassell BW, Salloum FN, Lewis EC, Voelkel N, Dinarello CA, Abbate A. Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury. J Mol Cell Cardiol. 2011; 51 (2): 244-51.
-
(2011)
J Mol Cell Cardiol.
, vol.51
, Issue.2
, pp. 244-251
-
-
Toldo, S.1
Seropian, I.M.2
Mezzaroma, E.3
Van Tassell, B.W.4
Salloum, F.N.5
Lewis, E.C.6
Voelkel, N.7
Dinarello, C.A.8
Abbate, A.9
-
247
-
-
0034194055
-
The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells
-
Young JL, Sukhova GK, Foster D, Kisiel W, Libby P, Schönbeck U. The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells. J Exp Med. 2000; 191 (9): 1535-44.
-
(2000)
J Exp Med.
, vol.191
, Issue.9
, pp. 1535-1544
-
-
Young, J.L.1
Sukhova, G.K.2
Foster, D.3
Kisiel, W.4
Libby, P.5
Schönbeck, U.6
-
248
-
-
84883127402
-
LRRFIP2 negatively regulates NLRP3 inflammasome activation in macrophages by promoting Flightless-I-mediated caspase-1 inhibition
-
Jin J, Yu Q, Han C, Hu X, Xu S, Wang Q, Wang J, Li N, Cao X. LRRFIP2 negatively regulates NLRP3 inflammasome activation in macrophages by promoting Flightless-I-mediated caspase-1 inhibition. Nat Commun. 2013; 4: 2075.
-
(2013)
Nat Commun.
, vol.4
, pp. 2075
-
-
Jin, J.1
Yu, Q.2
Han, C.3
Hu, X.4
Xu, S.5
Wang, Q.6
Wang, J.7
Li, N.8
Cao, X.9
|