Histones trigger sterile inflammation by activating the NLRP3 inflammasome

European Journal of Immunology

Volumn 43, Issue 12, 2013, Pages 3336-3342

  Allam, Ramanjaneyulu ^a   Darisipudi, Murthy Narayana ^b   Tschopp, Jurg ^a   Anders, Hans Joachim ^b  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Histones; Inflammasome; Interleukin 1; NLRP3; Sterile inflammation

Indexed keywords

CRYOPYRIN; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NEUTRALIZING ANTIBODY; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; CYTOSKELETON PROTEIN; HISTONE; INFLAMMASOME; INTERLEUKIN 1; NLRP3; PYCARD PROTEIN, MOUSE;

ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYMATIC DEGRADATION; GENE DELETION; INFLAMMATION; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SECRETION; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; NECROSIS; PATHOLOGY; PROTEIN DEGRADATION;

HISTONES; INFLAMMASOME; INTERLEUKIN-1; NLRP3; STERILE INFLAMMATION;

ANIMALS; ANTIBODIES, NEUTRALIZING; CARRIER PROTEINS; CASPASE 1; CYTOSKELETAL PROTEINS; GENE DELETION; HISTONES; INFLAMMASOMES; INFLAMMATION; INTERLEUKIN-18; INTERLEUKIN-1BETA; MICE; MICE, KNOCKOUT; NECROSIS; NEUTROPHILS; OXIDATIVE STRESS; PROTEOLYSIS;

EID: 84896844884     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201243224     Document Type: Article

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