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Volumn 13, Issue 9, 2012, Pages 566-578

Mitochondria as sensors and regulators of calcium signalling

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CHAPERONE; MITOFUSIN 2; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; VOLTAGE DEPENDENT ANION CHANNEL;

EID: 84865427488     PISSN: 14710072     EISSN: 14710080     Source Type: Journal    
DOI: 10.1038/nrm3412     Document Type: Review
Times cited : (1348)

References (177)
  • 1
    • 37149029370 scopus 로고    scopus 로고
    • Calcium signaling
    • DOI 10.1016/j.cell.2007.11.028, PII S0092867407015310
    • Clapham, D. E. Calcium signaling. Cell 131, 1047-1058 (2007). (Pubitemid 350258556)
    • (2007) Cell , vol.131 , Issue.6 , pp. 1047-1058
    • Clapham, D.E.1
  • 3
    • 84944816012 scopus 로고
    • A third contribution regarding the influence of the inorganic constituents of the blood on the ventricular contraction
    • Ringer, S. A third contribution regarding the influence of the inorganic constituents of the blood on the ventricular contraction. J. Physiol. 4, 222-225 (1883).
    • (1883) J. Physiol. , vol.4 , pp. 222-225
    • Ringer, S.1
  • 4
    • 0025477261 scopus 로고
    • Calcium oscillations: Phenomena, mechanisms and significance
    • Cobbold, P. H. & Cuthbertson, K. S. Calcium oscillations: phenomena, mechanisms and significance. Semin. Cell Biol. 1, 311-321 (1990).
    • (1990) Semin. Cell Biol. , vol.1 , pp. 311-321
    • Cobbold, P.H.1    Cuthbertson, K.S.2
  • 5
    • 0029143569 scopus 로고
    • Decoding of cytosolic calcium oscillations in the mitochondria
    • Hajnoczky, G., Robb-Gaspers, L. D., Seitz, M. B. & Thomas, A. P. Decoding of cytosolic calcium oscillations in the mitochondria. Cell 82, 415-424 (1995).
    • (1995) Cell , vol.82 , pp. 415-424
    • Hajnoczky, G.1    Robb-Gaspers, L.D.2    Seitz, M.B.3    Thomas, A.P.4
  • 6
    • 0032580202 scopus 로고    scopus 로고
    • Calcium oscillations increase the efficiency and specificity of gene expression
    • DOI 10.1038/31960
    • Dolmetsch, R. E., Xu, K. & Lewis, R. S. Calcium oscillations increase the efficiency and specificity of gene expression. Nature 392, 933-936 (1998). (Pubitemid 28232066)
    • (1998) Nature , vol.392 , Issue.6679 , pp. 933-936
    • Dolmetsch, R.E.1    Xu, K.2    Lewis, R.S.3
  • 7
    • 33644847375 scopus 로고    scopus 로고
    • 2+: Molecular determinants and functional consequences
    • 2+: molecular determinants and functional consequences. Physiol. Rev. 86, 369-408 (2006).
    • (2006) Physiol. Rev. , vol.86 , pp. 369-408
    • Rizzuto, R.1    Pozzan, T.2
  • 8
    • 0028283948 scopus 로고
    • Molecular and cellular physiology of intracellular calcium stores
    • Pozzan, T., Rizzuto, R., Volpe, P. & Meldolesi, J. Molecular and cellular physiology of intracellular calcium stores. Physiol. Rev. 74, 595-636 (1994). (Pubitemid 24224340)
    • (1994) Physiological Reviews , vol.74 , Issue.3 , pp. 595-636
    • Pozzan, T.1    Rizzuto, R.2    Volpe, P.3    Meldolesi, J.4
  • 9
    • 0020643801 scopus 로고
    • 2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate
    • 2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1, 4, 5-trisphosphate. Nature 306, 67-69 (1983). (Pubitemid 13022768)
    • (1983) Nature , vol.306 , Issue.5938 , pp. 67-69
    • Streb, H.1    Irvine, R.F.2    Berridge, M.J.3    Schulz, I.4
  • 10
    • 0032530396 scopus 로고    scopus 로고
    • 2+ store, with functional properties distinct from those of the endoplasmic reticulum
    • DOI 10.1093/emboj/17.18.5298
    • 2+ store, with functional properties distinct from those of the endoplasmic reticulum. EMBO J. 17, 5298-5308 (1998). (Pubitemid 28427045)
    • (1998) EMBO Journal , vol.17 , Issue.18 , pp. 5298-5308
    • Pinton, P.1    Pozzan, T.2    Rizzuto, R.3
  • 11
    • 67349287016 scopus 로고    scopus 로고
    • NAADP mobilizes calcium from acidic organelles through two-pore channels
    • Calcraft, P. J. et al. NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature 459, 596-600 (2009).
    • (2009) Nature , vol.459 , pp. 596-600
    • Calcraft, P.J.1
  • 12
    • 0035224759 scopus 로고    scopus 로고
    • The versatility and complexity of calcium signalling
    • Berridge, M. J. The versatility and complexity of calcium signalling. Novartis Found. Symp. 239, 52-64 (2001). (Pubitemid 33599034)
    • (2001) Novartis Foundation Symposium , vol.239 , pp. 52-64
    • Berridge, M.J.1
  • 13
    • 0001081063 scopus 로고
    • Ca ion uptake by rat kidney mitochondria and its dependence on respiration and phosphorylation
    • Vasington, F. D. & Murphy, J. V. Ca ion uptake by rat kidney mitochondria and its dependence on respiration and phosphorylation. J. Biol. Chem. 237, 2670-2677 (1962).
    • (1962) J. Biol. Chem. , vol.237 , pp. 2670-2677
    • Vasington, F.D.1    Murphy, J.V.2
  • 14
    • 73049130730 scopus 로고
    • Calcium uptake by rat kidney mitochondria
    • Deluca, H. F. & Engstrom, G. W. Calcium uptake by rat kidney mitochondria. Proc. Natl Acad. Sci. USA 47, 1744-1750 (1961).
    • (1961) Proc. Natl Acad. Sci. USA , vol.47 , pp. 1744-1750
    • Deluca, H.F.1    Engstrom, G.W.2
  • 15
    • 0001349817 scopus 로고
    • Respiration-dependent accumulation of inorganic phosphate and Ca ions by rat liver mitochondria
    • Lehninger, A. L., Rossi, C. S. & Greenawalt, J. W. Respiration-dependent accumulation of inorganic phosphate and Ca ions by rat liver mitochondria. Biochem. Biophys. Res. Commun. 10, 444-448 (1963).
    • (1963) Biochem. Biophys. Res. Commun. , vol.10 , pp. 444-448
    • Lehninger, A.L.1    Rossi, C.S.2    Greenawalt, J.W.3
  • 16
    • 0014202070 scopus 로고
    • Chemiosmotic hypothesis of oxidative phosphorylation
    • Mitchell, P. & Moyle, J. Chemiosmotic hypothesis of oxidative phosphorylation. Nature 213, 137-139 (1967).
    • (1967) Nature , vol.213 , pp. 137-139
    • Mitchell, P.1    Moyle, J.2
  • 17
    • 0033607504 scopus 로고    scopus 로고
    • Molecular architecture of the rotary motor in ATP synthase
    • Stock, D., Leslie, A. G. & Walker, J. E. Molecular architecture of the rotary motor in ATP synthase. Science 286, 1700-1705 (1999). (Pubitemid 129515869)
    • (1999) Science , vol.286 , Issue.5445 , pp. 1700-1705
    • Stock, D.1    Leslie, A.G.W.2    Walker, J.E.3
  • 18
    • 0021759404 scopus 로고
    • Pathway for uncoupler-induced calcium efflux in rat liver mitochondria: Inhibition by ruthenium red
    • Bernardi, P., Paradisi, V., Pozzan, T. & Azzone, G. F. Pathway for uncoupler-induced calcium efflux in rat liver mitochondria: inhibition by ruthenium red. Biochemistry 23, 1645-1651 (1984).
    • (1984) Biochemistry , vol.23 , pp. 1645-1651
    • Bernardi, P.1    Paradisi, V.2    Pozzan, T.3    Azzone, G.F.4
  • 19
    • 0014533147 scopus 로고
    • Inhibition and activation of calcium transport in mitochondria. Effect of lanthanides and local anesthetic drugs
    • Mela, L. Inhibition and activation of calcium transport in mitochondria. Effect of lanthanides and local anesthetic drugs. Biochemistry 8, 2481-2486 (1969).
    • (1969) Biochemistry , vol.8 , pp. 2481-2486
    • Mela, L.1
  • 20
    • 0018291238 scopus 로고
    • 2+ transport in rat liver mitochondria
    • DOI 10.1016/0014-5793(79)80849-2
    • 2+ transport in rat liver mitochondria. FEBS Lett. 104, 347-351 (1979). (Pubitemid 9243479)
    • (1979) FEBS Letters , vol.104 , Issue.2 , pp. 347-351
    • Bragadin, M.1    Pozzan, T.2    Azzone, G.F.3
  • 21
    • 0017716659 scopus 로고
    • The calcium induced and sodium induced effluxes of calcium from heart mitochondria. Evidence for a sodium calcium carrier
    • DOI 10.1111/j.1432-1033.1977.tb11839.x
    • Crompton, M., Kunzi, M. & Carafoli, E. The calcium-induced and sodium-induced effluxes of calcium from heart mitochondria. Evidence for a sodium-calcium carrier. Eur. J. Biochem. 79, 549-558 (1977). (Pubitemid 8198818)
    • (1977) European Journal of Biochemistry , vol.79 , Issue.2 , pp. 549-558
    • Crompton, A.1    Kuenzi, M.2    Carafoli, E.3
  • 27
    • 0027340729 scopus 로고
    • 3-sensitive channels that are sensed by neighboring mitochondria
    • 2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria. Science 262, 744-747 (1993). (Pubitemid 23350694)
    • (1993) Science , vol.262 , Issue.5134 , pp. 744-747
    • Rizzuto, R.1    Brini, M.2    Murgia, M.3    Pozzan, T.4
  • 29
    • 0033792131 scopus 로고    scopus 로고
    • 2+ transients that modulate secretion
    • 2+ transients that modulate secretion. Nature Cell Biol. 2, 57-61 (2000).
    • (2000) Nature Cell Biol , vol.2 , pp. 57-61
    • Montero, M.1
  • 31
    • 0033521586 scopus 로고    scopus 로고
    • Quasi-synaptic calcium signal transmission between endoplasmic reticulum and mitochondria
    • DOI 10.1093/emboj/18.1.96
    • Csordas, G., Thomas, A. P. & Hajnoczky, G. Quasi-synaptic calcium signal transmission between endoplasmic reticulum and mitochondria. EMBO J. 18, 96-108 (1999). (Pubitemid 29005027)
    • (1999) EMBO Journal , vol.18 , Issue.1 , pp. 96-108
    • Csordas, G.1    Thomas, A.P.2    Hajnoczky, G.3
  • 32
    • 0034686014 scopus 로고    scopus 로고
    • Calcium signal transmission between ryanodine receptors and mitochondria
    • DOI 10.1074/jbc.275.20.15305
    • Szalai, G., Csordas, G., Hantash, B. M., Thomas, A. P. & Hajnoczky, G. Calcium signal transmission between ryanodine receptors and mitochondria. J. Biol. Chem. 275, 15305-15313 (2000). (Pubitemid 30337257)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.20 , pp. 15305-15313
    • Szalait, G.1    Csordast, G.2    Hantash, B.M.3    Thomas, A.P.4    Hajnoczky, G.5
  • 33
    • 0032425805 scopus 로고    scopus 로고
    • Electron microscopic tomography of rat-liver mitochondria and their interactions with the endoplasmic reticulum
    • Mannella, C. A., Buttle, K., Rath, B. K. &Marko, M. Electron microscopic tomography of rat-liver mitochondria and their interaction with the endoplasmic reticulum. Biofactors 8, 225-228 (1998). (Pubitemid 29021352)
    • (1998) BioFactors , vol.8 , Issue.3-4 , pp. 225-228
    • Mannella, C.A.1    Buttle, K.2    Rath, B.K.3    Marko, M.4
  • 34
    • 15544368216 scopus 로고    scopus 로고
    • Store-operated calcium channels
    • DOI 10.1152/physrev.00057.2003
    • Parekh, A. B. & Putney, J. W. Jr. Store-operated calcium channels. Physiol. Rev. 85, 757-810 (2005). (Pubitemid 40404641)
    • (2005) Physiological Reviews , vol.85 , Issue.2 , pp. 757-810
    • Parekh, A.B.1    Putney Jr., J.W.2
  • 36
  • 38
    • 77950888855 scopus 로고    scopus 로고
    • 2+ channels
    • 2+ channels. Mol. Cell 38, 280-290 (2010).
    • (2010) Mol. Cell , vol.38 , pp. 280-290
    • Giacomello, M.1
  • 39
    • 77954301751 scopus 로고    scopus 로고
    • Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface
    • Csordas, G. et al. Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface. Mol. Cell 39, 121-132 (2010).
    • (2010) Mol. Cell , vol.39 , pp. 121-132
    • Csordas, G.1
  • 40
    • 0035842896 scopus 로고    scopus 로고
    • VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release
    • DOI 10.1083/jcb.200105057
    • Madesh, M. & Hajnoczky, G. VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release. J. Cell Biol. 155, 1003-1015 (2001). (Pubitemid 34286251)
    • (2001) Journal of Cell Biology , vol.155 , Issue.6 , pp. 1003-1015
    • Madesh, M.1    Hajnoczky, G.2
  • 41
    • 0037175393 scopus 로고    scopus 로고
    • 2+ microdomains to mitochondria
    • 2+ microdomains to mitochondria. J. Cell Biol. 159, 613-624 (2002).
    • (2002) J. Cell Biol. , vol.159 , pp. 613-624
    • Rapizzi, E.1
  • 42
    • 34948846577 scopus 로고    scopus 로고
    • VDAC closure increases calcium ion flux
    • DOI 10.1016/j.bbamem.2007.06.002, PII S0005273607002131
    • Tan, W. & Colombini, M. VDAC closure increases calcium ion flux. Biochim. Biophys. Acta 1768, 2510-2515 (2007). (Pubitemid 47532032)
    • (2007) Biochimica et Biophysica Acta - Biomembranes , vol.1768 , Issue.10 , pp. 2510-2515
    • Tan, W.1    Colombini, M.2
  • 43
    • 52449104836 scopus 로고    scopus 로고
    • VDAC regulation: Role of cytosolic proteins and mitochondrial lipids
    • Rostovtseva, T. K. & Bezrukov, S. M. VDAC regulation: role of cytosolic proteins and mitochondrial lipids. J. Bioenerg. Biomembr. 40, 163-170 (2008).
    • (2008) J. Bioenerg. Biomembr. , vol.40 , pp. 163-170
    • Rostovtseva, T.K.1    Bezrukov, S.M.2
  • 44
    • 0032765963 scopus 로고    scopus 로고
    • Mouse VDAC isoforms expressed in yeast: Channel properties and their roles in mitochondrial outer membrane permeability
    • DOI 10.1007/s002329900540
    • Xu, X., Decker, W., Sampson, M. J., Craigen, W. J. & Colombini, M. Mouse VDAC isoforms expressed in yeast: channel properties and their roles in mitochondrial outer membrane permeability. J. Membr. Biol. 170, 89-102 (1999). (Pubitemid 29367689)
    • (1999) Journal of Membrane Biology , vol.170 , Issue.2 , pp. 89-102
    • Xu, X.1    Decker, W.2    Sampson, M.J.3    Craigen, W.J.4    Colombini, M.5
  • 45
    • 84855658120 scopus 로고    scopus 로고
    • 2+ signals to mitochondria
    • 2+ signals to mitochondria. Cell Death Differ. 19, 267-273 (2012).
    • (2012) Cell Death Differ , vol.19 , pp. 267-273
    • De Stefani, D.1
  • 46
    • 59649092928 scopus 로고    scopus 로고
    • 2+-dependent cell survival and death
    • 2+-dependent cell survival and death. Mol. Cell 33, 377-388 (2009).
    • (2009) Mol. Cell , vol.33 , pp. 377-388
    • Roy, S.S.1
  • 47
    • 73849084212 scopus 로고    scopus 로고
    • VDAC2 is required for truncated BID-induced mitochondrial apoptosis by recruiting BAK to the mitochondria
    • Roy, S. S., Ehrlich, A. M., Craigen, W. J. & Hajnoczky, G. VDAC2 is required for truncated BID-induced mitochondrial apoptosis by recruiting BAK to the mitochondria. EMBO Rep. 10, 1341-1347 (2009).
    • (2009) EMBO Rep , vol.10 , pp. 1341-1347
    • Roy, S.S.1    Ehrlich, A.M.2    Craigen, W.J.3    Hajnoczky, G.4
  • 48
    • 0043204996 scopus 로고    scopus 로고
    • VDAC2 inhibits BAK activation and mitochondrial apoptosis
    • DOI 10.1126/science.1083995
    • Cheng, E. H., Sheiko, T. V., Fisher, J. K., Craigen, W. J. & Korsmeyer, S. J. VDAC2 inhibits BAK activation and mitochondrial apoptosis. Science 301, 513-517 (2003). (Pubitemid 36900308)
    • (2003) Science , vol.301 , Issue.5632 , pp. 513-517
    • Cheng, E.H.-Y.1    Sheiko, T.V.2    Fisher, J.K.3    Craigen, W.J.4    Korsmeyer, S.J.5
  • 49
    • 1642540210 scopus 로고    scopus 로고
    • The mitochondrial calcium uniporter is a highly selective ion channel
    • DOI 10.1038/nature02246
    • Kirichok, Y., Krapivinsky, G. & Clapham, D. E. The mitochondrial calcium uniporter is a highly selective ion channel. Nature 427, 360-364 (2004). (Pubitemid 38133664)
    • (2004) Nature , vol.427 , Issue.6972 , pp. 360-364
    • Kirichok, Y.1    Krapivinsky, G.2    Clapham, D.E.3
  • 50
    • 80051936634 scopus 로고    scopus 로고
    • A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
    • De Stefani, D., Raffaello, A., Teardo, E., Szabo, I. & Rizzuto, R. A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature 476, 336-340 (2011).
    • (2011) Nature , vol.476 , pp. 336-340
    • De Stefani, D.1    Raffaello, A.2    Teardo, E.3    Szabo, I.4    Rizzuto, R.5
  • 51
    • 80051946060 scopus 로고    scopus 로고
    • Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
    • Baughman, J. M. et al. Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature 476, 341-345 (2011).
    • (2011) Nature , vol.476 , pp. 341-345
    • Baughman, J.M.1
  • 52
    • 77956928316 scopus 로고    scopus 로고
    • 2+ uptake
    • 2+ uptake. Nature 467, 291-296 (2010).
    • (2010) Nature , vol.467 , pp. 291-296
    • Perocchi, F.1
  • 54
    • 0032827410 scopus 로고    scopus 로고
    • Mitochondrial transport of cations: Channels, exchangers, and permeability transition
    • Bernardi, P. Mitochondrial transport of cations: channels, exchangers, and permeability transition. Physiol. Rev. 79, 1127-1155 (1999). (Pubitemid 29473313)
    • (1999) Physiological Reviews , vol.79 , Issue.4 , pp. 1127-1155
    • Bernardi, P.1
  • 56
    • 1242339614 scopus 로고    scopus 로고
    • 2+ Exchanger Gene Family, NCKX6
    • DOI 10.1074/jbc.M310908200
    • 2+ exchanger gene family, NCKX6. J. Biol. Chem. 279, 5867-5876 (2004). (Pubitemid 38220619)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.7 , pp. 5867-5876
    • Cai, X.1    Lytton, J.2
  • 59
    • 0031587822 scopus 로고    scopus 로고
    • Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals
    • Ichas, F., Jouaville, L. S. & Mazat, J. P. Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals. Cell 89, 1145-1153 (1997). (Pubitemid 127678747)
    • (1997) Cell , vol.89 , Issue.7 , pp. 1145-1153
    • Ichas, F.1    Jouaville, L.S.2    Mazat, J.-P.3
  • 60
    • 77957842939 scopus 로고    scopus 로고
    • 2+ exchange, metabolic flexibility, and propensity for heart failure in mice
    • 2+ exchange, metabolic flexibility, and propensity for heart failure in mice. J. Clin. Invest. 120, 3680-3687 (2010).
    • (2010) J. Clin. Invest. , vol.120 , pp. 3680-3687
    • Elrod, J.W.1
  • 61
    • 79952444039 scopus 로고    scopus 로고
    • 2+ responses to physiological stimuli in adult neurons
    • 2+ responses to physiological stimuli in adult neurons. Eur. J. Neurosci. 33, 831-842 (2011).
    • (2011) Eur. J. Neurosci. , vol.33 , pp. 831-842
    • Barsukova, A.1
  • 62
    • 79960943442 scopus 로고    scopus 로고
    • Mitochondrial calcium and its regulation in neurodegeneration induced by oxidative stress
    • Barsukova, A. G., Bourdette, D. & Forte, M. Mitochondrial calcium and its regulation in neurodegeneration induced by oxidative stress. Eur. J. Neurosci. 34, 437-447 (2011).
    • (2011) Eur. J. Neurosci. , vol.34 , pp. 437-447
    • Barsukova, A.G.1    Bourdette, D.2    Forte, M.3
  • 63
    • 0025273937 scopus 로고
    • Phospholipid synthesis in a membrane fraction associated with mitochondria
    • Vance, J. E. Phospholipid synthesis in a membrane fraction associated with mitochondria. J. Biol. Chem. 265, 7248-7256 (1990).
    • (1990) J. Biol. Chem. , vol.265 , pp. 7248-7256
    • Vance, J.E.1
  • 64
    • 0027973135 scopus 로고
    • A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteins
    • Rusinol, A. E., Cui, Z., Chen, M. H. & Vance, J. E. A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteins. J. Biol. Chem. 269, 27494-27502 (1994). (Pubitemid 24346578)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.44 , pp. 27494-27502
    • Rusinol, A.E.1    Cui, Z.2    Chen, M.H.3    Vance, J.E.4
  • 65
    • 4544261024 scopus 로고    scopus 로고
    • Subcellular compartmentalization of ceramide metabolism: MAM (mitochondria-associated membrane) and/or mitochondria?
    • DOI 10.1042/BJ20031819
    • Bionda, C., Portoukalian, J., Schmitt, D., Rodriguez-Lafrasse, C. & Ardail, D. Subcellular compartmentalization of ceramide metabolism: MAM (mitochondria-associated membrane) and/or mitochondria? Biochem. J. 382, 527-533 (2004). (Pubitemid 39243919)
    • (2004) Biochemical Journal , vol.382 , Issue.2 , pp. 527-533
    • Bionda, C.1    Portoukalian, J.2    Schmitt, D.3    Rodriguez-Lafrasse, C.4    Ardail, D.5
  • 66
    • 0035816532 scopus 로고    scopus 로고
    • Acyl-CoA synthetase isoforms 1, 4, and 5 are present in different subcellular membranes in rat liver and can be inhibited independently
    • Lewin, T. M., Kim, J. H., Granger, D. A., Vance, J. E. & Coleman, R. A. Acyl-CoA synthetase isoforms 1, 4, and 5 are present in different subcellular membranes in rat liver and can be inhibited independently. J. Biol. Chem. 276, 24674-24679 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 24674-24679
    • Lewin, T.M.1    Kim, J.H.2    Granger, D.A.3    Vance, J.E.4    Coleman, R.A.5
  • 67
    • 68949192292 scopus 로고    scopus 로고
    • Interactions between the endoplasmic reticulum, mitochondria, plasma membrane and other subcellular organelles
    • Lebiedzinska, M., Szabadkai, G., Jones, A. W., Duszynski, J. & Wieckowski, M. R. Interactions between the endoplasmic reticulum, mitochondria, plasma membrane and other subcellular organelles. Int. J. Biochem. Cell Biol. 41, 1805-1816 (2009).
    • (2009) Int. J. Biochem. Cell Biol. , vol.41 , pp. 1805-1816
    • Lebiedzinska, M.1    Szabadkai, G.2    Jones, A.W.3    Duszynski, J.4    Wieckowski, M.R.5
  • 68
    • 69049098806 scopus 로고    scopus 로고
    • Structural and functional link between the mitochondrial network and the endoplasmic reticulum
    • Giorgi, C., De Stefani, D., Bononi, A., Rizzuto, R. & Pinton, P. Structural and functional link between the mitochondrial network and the endoplasmic reticulum. Int. J. Biochem. Cell Biol. 41, 1817-1827 (2009).
    • (2009) Int. J. Biochem. Cell Biol. , vol.41 , pp. 1817-1827
    • Giorgi, C.1    De Stefani, D.2    Bononi, A.3    Rizzuto, R.4    Pinton, P.5
  • 70
    • 67349222523 scopus 로고    scopus 로고
    • Controlling metabolism and cell death: At the heart of mitochondrial calcium signalling
    • Murgia, M., Giorgi, C., Pinton, P. & Rizzuto, R. Controlling metabolism and cell death: at the heart of mitochondrial calcium signalling. J. Mol. Cell. Cardiol. 46, 781-788 (2009).
    • (2009) J. Mol. Cell. Cardiol. , vol.46 , pp. 781-788
    • Murgia, M.1    Giorgi, C.2    Pinton, P.3    Rizzuto, R.4
  • 71
    • 68649115556 scopus 로고    scopus 로고
    • 2+ transfer from the ER to mitochondria: When, how and why
    • 2+ transfer from the ER to mitochondria: when, how and why. Biochim. Biophys. Acta 1787, 1342-1351 (2009).
    • (2009) Biochim. Biophys. Acta , vol.1787 , pp. 1342-1351
    • Rizzuto, R.1
  • 72
    • 57349100367 scopus 로고    scopus 로고
    • Mitofusin 2 tethers endoplasmic reticulum to mitochondria
    • de Brito, O. M. & Scorrano, L. Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 456, 605-610 (2008).
    • (2008) Nature , vol.456 , pp. 605-610
    • De Brito, O.M.1    Scorrano, L.2
  • 74
    • 58549119743 scopus 로고    scopus 로고
    • 2+-dependent control of mitochondrial dynamics by the Miro GTPase
    • 2+-dependent control of mitochondrial dynamics by the Miro GTPase. Proc. Natl Acad. Sci. USA 105, 20728-20733 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 20728-20733
    • Saotome, M.1
  • 76
    • 78049342172 scopus 로고    scopus 로고
    • Trichoplein/mitostatin regulates endoplasmic reticulum-mitochondria juxtaposition
    • Cerqua, C. et al. Trichoplein/mitostatin regulates endoplasmic reticulum-mitochondria juxtaposition. EMBO Rep. 11, 854-860 (2010).
    • (2010) EMBO Rep , vol.11 , pp. 854-860
    • Cerqua, C.1
  • 79
    • 77955824765 scopus 로고    scopus 로고
    • An intimate liaison: Spatial organization of the endoplasmic reticulum-mitochondria relationship
    • de Brito, O. M. & Scorrano, L. An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship. EMBO J. 29, 2715-2723 (2010).
    • (2010) EMBO J , vol.29 , pp. 2715-2723
    • De Brito, O.M.1    Scorrano, L.2
  • 80
    • 35549006797 scopus 로고    scopus 로고
    • 2+ signaling and cell survival
    • DOI 10.1016/j.cell.2007.08.036, PII S0092867407010999
    • 2+ signaling and cell survival. Cell 131, 596-610 (2007). (Pubitemid 350017760)
    • (2007) Cell , vol.131 , Issue.3 , pp. 596-610
    • Hayashi, T.1    Su, T.-P.2
  • 81
    • 51349169022 scopus 로고    scopus 로고
    • The subcellular distribution of calnexin is mediated by PACS-2
    • Myhill, N. et al. The subcellular distribution of calnexin is mediated by PACS-2. Mol. Biol. Cell 19, 2777-2788 (2008).
    • (2008) Mol. Biol. Cell , vol.19 , pp. 2777-2788
    • Myhill, N.1
  • 83
    • 0347753252 scopus 로고    scopus 로고
    • 2+-dependent redox modulation of SERCA 2b by ERp57
    • DOI 10.1083/jcb.200307010
    • 2+-dependent redox modulation of SERCA 2b by ERp57. J. Cell Biol. 164, 35-46 (2004). (Pubitemid 38082455)
    • (2004) Journal of Cell Biology , vol.164 , Issue.1 , pp. 35-46
    • Li, Y.1    Camacho, P.2
  • 86
    • 78649425814 scopus 로고    scopus 로고
    • PML regulates apoptosis at endoplasmic reticulum by modulating calcium release
    • Giorgi, C. et al. PML regulates apoptosis at endoplasmic reticulum by modulating calcium release. Science 330, 1247-1251 (2010).
    • (2010) Science , vol.330 , pp. 1247-1251
    • Giorgi, C.1
  • 87
    • 0026432666 scopus 로고
    • 3- and calcium-gated channels from endoplasmic reticulum of cerebellum
    • 3-and calcium-gated channels from endoplasmic reticulum of cerebellum. Nature 351, 751-754 (1991). (Pubitemid 21896682)
    • (1991) Nature , vol.351 , Issue.6329 , pp. 751-754
    • Bezprozvanny, I.1    Watras, J.2    Ehrlich, B.E.3
  • 88
    • 0029099030 scopus 로고
    • Synchronization of calcium waves by mitochondrial substrates in Xenopus laevis oocytes
    • Jouaville, L. S., Ichas, F., Holmuhamedov, E. L., Camacho, P. & Lechleiter, J. D. Synchronization of calcium waves by mitochondrial substrates in Xenopus laevis oocytes. Nature 377, 438-441 (1995).
    • (1995) Nature , vol.377 , pp. 438-441
    • Jouaville, L.S.1    Ichas, F.2    Holmuhamedov, E.L.3    Camacho, P.4    Lechleiter, J.D.5
  • 92
    • 80053577351 scopus 로고    scopus 로고
    • Calcium microdomains at the immunological synapse: How ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation
    • Quintana, A. et al. Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation. EMBO J. 30, 3895-3912 (2011).
    • (2011) EMBO J , vol.30 , pp. 3895-3912
    • Quintana, A.1
  • 93
    • 0030982181 scopus 로고    scopus 로고
    • Mitochondrial regulation of store-operated calcium signaling in T lymphocytes
    • DOI 10.1083/jcb.137.3.633
    • Hoth, M., Fanger, C. M. & Lewis, R. S. Mitochondrial regulation of store-operated calcium signaling in T lymphocytes. J. Cell Biol. 137, 633-648 (1997). (Pubitemid 27200666)
    • (1997) Journal of Cell Biology , vol.137 , Issue.3 , pp. 633-648
    • Hoth, M.1    Fanger, C.M.2    Lewis, R.S.3
  • 94
    • 0034641757 scopus 로고    scopus 로고
    • Mitochondrial control of calcium-channel gating: A mechanism for sustained signaling and transcriptional activation in T lymphocytes
    • Hoth, M., Button, D. C. & Lewis, R. S. Mitochondrial control of calcium-channel gating: a mechanism for sustained signaling and transcriptional activation in T lymphocytes. Proc. Natl Acad. Sci. USA 97, 10607-10612 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 10607-10612
    • Hoth, M.1    Button, D.C.2    Lewis, R.S.3
  • 95
    • 79953317444 scopus 로고    scopus 로고
    • 2+ store to the plasma membrane in cells with depolarized mitochondria
    • 2+ store to the plasma membrane in cells with depolarized mitochondria. J. Biol. Chem. 286, 12189-12201 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 12189-12201
    • Singaravelu, K.1
  • 97
    • 0035355195 scopus 로고    scopus 로고
    • Energized mitochondria increase the dynamic range over which inositol 1,4,5-trisphosphate activates store-operated calcium influx
    • DOI 10.1093/emboj/20.11.2672
    • Gilabert, J. A., Bakowski, D. & Parekh, A. B. Energized mitochondria increase the dynamic range over which inositol 1, 4, 5-trisphosphate activates store-operated calcium influx. EMBO J. 20, 2672-2679 (2001). (Pubitemid 32938552)
    • (2001) EMBO Journal , vol.20 , Issue.11 , pp. 2672-2679
    • Gilabert, J.A.1    Bakowski, D.2    Parekh, A.B.3
  • 98
    • 0033179293 scopus 로고    scopus 로고
    • Depolarization-induced mitochondrial Ca accumulation in sympathetic neurons: Spatial and temporal characteristics
    • Pivovarova, N. B., Hongpaisan, J., Andrews, S. B. & Friel, D. D. Depolarization-induced mitochondrial Ca accumulation in sympathetic neurons: spatial and temporal characteristics. J. Neurosci. 19, 6372-6384 (1999). (Pubitemid 29347437)
    • (1999) Journal of Neuroscience , vol.19 , Issue.15 , pp. 6372-6384
    • Pivovarova, N.B.1    Hongpaisan, J.2    Andrews, S.B.3    Friel, D.D.4
  • 99
    • 0030891028 scopus 로고    scopus 로고
    • Mitochondrial involvement in post-tetanic potentiation of synaptic transmission
    • DOI 10.1016/S0896-6273(00)81248-9
    • Tang, Y. & Zucker, R. S. Mitochondrial involvement in post-tetanic potentiation of synaptic transmission. Neuron 18, 483-491 (1997). (Pubitemid 27138795)
    • (1997) Neuron , vol.18 , Issue.3 , pp. 483-491
    • Tang, Y.-G.1    Zucker, R.S.2
  • 100
    • 0037101606 scopus 로고    scopus 로고
    • Presynaptic mitochondrial calcium sequestration influences transmission at mammalian central synapses
    • Billups, B. & Forsythe, I. D. Presynaptic mitochondrial calcium sequestration influences transmission at mammalian central synapses. J. Neurosci. 22, 5840-5847 (2002). (Pubitemid 35387628)
    • (2002) Journal of Neuroscience , vol.22 , Issue.14 , pp. 5840-5847
    • Billups, B.1    Forsythe, I.D.2
  • 101
    • 0036092524 scopus 로고    scopus 로고
    • 2+ buffering regulates synaptic transmission between retinal amacrine cells
    • 2+ buffering regulates synaptic transmission between retinal amacrine cells. J. Neurophysiol. 87, 1426-1439 (2002). (Pubitemid 34670810)
    • (2002) Journal of Neurophysiology , vol.87 , Issue.3 , pp. 1426-1439
    • Medler, K.1    Gleason, E.L.2
  • 103
    • 0038414654 scopus 로고    scopus 로고
    • 2+ uptake prevents desynchronization of quantal release and minimizes depletion during repetitive stimulation of mouse motor nerve terminals
    • DOI 10.1113/jphysiol.2002.035196
    • 2+ uptake prevents desynchronization of quantal release and minimizes depletion during repetitive stimulation of mouse motor nerve terminals. J. Physiol. 548, 425-438 (2003). (Pubitemid 36527465)
    • (2003) Journal of Physiology , vol.548 , Issue.2 , pp. 425-438
    • David, G.1    Barett, E.F.2
  • 105
    • 37749053855 scopus 로고    scopus 로고
    • Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation
    • Kang, J. S. et al. Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation. Cell 132, 137-148 (2008).
    • (2008) Cell , vol.132 , pp. 137-148
    • Kang, J.S.1
  • 106
    • 60449108890 scopus 로고    scopus 로고
    • Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses
    • Macaskill, A. F. et al. Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses. Neuron 61, 541-555 (2009).
    • (2009) Neuron , vol.61 , pp. 541-555
    • MacAskill, A.F.1
  • 107
    • 80053056620 scopus 로고    scopus 로고
    • 2+ as an intrinsic signal regulating mitochondrial motility in axons
    • 2+ as an intrinsic signal regulating mitochondrial motility in axons. Proc. Natl Acad. Sci. USA 108, 15456-15461 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 15456-15461
    • Chang, K.T.1    Niescier, R.F.2    Min, K.T.3
  • 108
    • 84860300071 scopus 로고    scopus 로고
    • 2+ mobilization is a key element in olfactory signaling
    • 2+ mobilization is a key element in olfactory signaling. Nature Neurosci. 15, 754-762 (2012).
    • (2012) Nature Neurosci , vol.15 , pp. 754-762
    • Fluegge, D.1
  • 109
    • 84856056846 scopus 로고    scopus 로고
    • Mitochondrial transport in neurons: Impact on synaptic homeostasis and neurodegeneration
    • Sheng, Z. H. & Cai, Q. Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration. Nature Rev. Neurosci. 13, 77-93 (2012).
    • (2012) Nature Rev. Neurosci. , vol.13 , pp. 77-93
    • Sheng, Z.H.1    Cai, Q.2
  • 113
    • 48549100809 scopus 로고    scopus 로고
    • 2+ signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells
    • 2+ signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells. Gastroenterology 135, 632-641 (2008).
    • (2008) Gastroenterology , vol.135 , pp. 632-641
    • Murphy, J.A.1
  • 115
    • 0025319665 scopus 로고
    • Role of calcium ions in regulation of mammalian intramitochondrial metabolism
    • McCormack, J. G., Halestrap, A. P. & Denton, R. M. Role of calcium ions in regulation of mammalian intramitochondrial metabolism. Physiol. Rev. 70, 391-425 (1990). (Pubitemid 20140186)
    • (1990) Physiological Reviews , vol.70 , Issue.2 , pp. 391-425
    • McCormack, J.G.1    Halestrap, A.P.2    Denton, R.M.3
  • 117
    • 0018363365 scopus 로고
    • The effects of calcium ions and adenine nucleotides on the activity of pig heart 2-oxoglutarate dehydrogenase complex
    • McCormack, J. G. & Denton, R. M. The effects of calcium ions and adenine nucleotides on the activity of pig heart 2-oxoglutarate dehydrogenase complex. Biochem. J. 180, 533-544 (1979). (Pubitemid 9208285)
    • (1979) Biochemical Journal , vol.180 , Issue.3 , pp. 533-544
    • McCormack, J.G.1    Denton, R.M.2
  • 118
    • 0033598828 scopus 로고    scopus 로고
    • Regulation of mitochondrial ATP synthesis by calcium: Evidence for a long-term metabolic priming
    • Jouaville, L. S., Pinton, P., Bastianutto, C., Rutter, G. A. & Rizzuto, R. Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic priming. Proc. Natl Acad. Sci. USA 96, 13807-13812 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 13807-13812
    • Jouaville, L.S.1    Pinton, P.2    Bastianutto, C.3    Rutter, G.A.4    Rizzuto, R.5
  • 119
    • 0032773120 scopus 로고    scopus 로고
    • A calcium signaling defect in the pathogenesis of a mitochondrial DNA inherited oxidative phosphorylation deficiency
    • DOI 10.1038/11396
    • Brini, M. et al. A calcium signaling defect in the pathogenesis of a mitochondrial DNA inherited oxidative phosphorylation deficiency. Nature Med. 5, 951-954 (1999). (Pubitemid 29372425)
    • (1999) Nature Medicine , vol.5 , Issue.8 , pp. 951-954
    • Brini, M.1    Pinton, P.2    King, M.P.3    Davidson, M.4    Schon, E.A.5    Rizzuto, R.6
  • 120
    • 4644326685 scopus 로고    scopus 로고
    • 2+ handling in human complex i deficiency
    • 2+ handling in human complex I deficiency. J. Biol. Chem. 279, 40328-40336 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 40328-40336
    • Visch, H.J.1
  • 121
    • 77951695106 scopus 로고    scopus 로고
    • Dynamic changes in cytosolic and mitochondrial ATP levels in pancreatic acinar cells
    • Voronina, S. G. et al. Dynamic changes in cytosolic and mitochondrial ATP levels in pancreatic acinar cells. Gastroenterology 138, 1976-1987 (2010).
    • (2010) Gastroenterology , vol.138 , pp. 1976-1987
    • Voronina, S.G.1
  • 122
    • 68649092333 scopus 로고    scopus 로고
    • 2+ signaling in the coordination of mitochondrial ATP production with cardiac work
    • 2+ signaling in the coordination of mitochondrial ATP production with cardiac work. Biochim. Biophys. Acta 1787, 1334-1341 (2009).
    • (2009) Biochim. Biophys. Acta , vol.1787 , pp. 1334-1341
    • Balaban, R.S.1
  • 123
    • 0141643240 scopus 로고    scopus 로고
    • 2+-sensitive aspartate/ glutamate carrier increases mitochondrial ATP production in agonist-stimulated Chinese hamster ovary cells
    • DOI 10.1074/jbc.M304988200
    • 2+-sensitive aspartate/glutamate carrier increases mitochondrial ATP production in agonist-stimulated Chinese hamster ovary cells. J. Biol. Chem. 278, 38686-38692 (2003). (Pubitemid 37221765)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.40 , pp. 38686-38692
    • Lasorsa, F.M.1    Pinton, P.2    Palmieri, L.3    Fiermonte, G.4    Rizzuto, R.5    Palmieri, F.6
  • 124
    • 34147167011 scopus 로고    scopus 로고
    • 2+ activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: Role in the heart malate-aspartate NADH shuttle
    • DOI 10.1074/jbc.M610491200
    • 2+ activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttle. J. Biol. Chem. 282, 7098-7106 (2007). (Pubitemid 47093651)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.10 , pp. 7098-7106
    • Contreras, L.1    Gomez-Puertas, P.2    Iijima, M.3    Kobayashi, K.4    Saheki, T.5    Satrustegui, J.6
  • 125
    • 33846796330 scopus 로고    scopus 로고
    • Mitochondrial transporters as novel targets for intracellular calcium signaling
    • DOI 10.1152/physrev.00005.2006
    • Satrustegui, J., Pardo, B. & Del Arco, A. Mitochondrial transporters as novel targets for intracellular calcium signaling. Physiol. Rev. 87, 29-67 (2007). (Pubitemid 46207712)
    • (2007) Physiological Reviews , vol.87 , Issue.1 , pp. 29-67
    • Satrustegui, J.1    Pardo, B.2    Del Arco, A.3
  • 127
    • 0034668803 scopus 로고    scopus 로고
    • Pathophysiological and protective roles of mitochondrial ion channels
    • O'Rourke, B. Pathophysiological and protective roles of mitochondrial ion channels. J. Physiol. 529, 23-36 (2000).
    • (2000) J. Physiol. , vol.529 , pp. 23-36
    • O'Rourke, B.1
  • 128
    • 67349164763 scopus 로고    scopus 로고
    • CaPful of mechanisms regulating the mitochondrial permeability transition
    • Di Lisa, F. & Bernardi, P. A. CaPful of mechanisms regulating the mitochondrial permeability transition. J. Mol. Cell. Cardiol. 46, 775-780 (2009).
    • (2009) J. Mol. Cell. Cardiol. , vol.46 , pp. 775-780
    • Di Lisa, F.1    Bernardi, P.A.2
  • 129
    • 68649104009 scopus 로고    scopus 로고
    • Mitochondrial calcium function and dysfunction in the central nervous system
    • Nicholls, D. G. Mitochondrial calcium function and dysfunction in the central nervous system. Biochim. Biophys. Acta 1787, 1416-1424 (2009).
    • (2009) Biochim. Biophys. Acta , vol.1787 , pp. 1416-1424
    • Nicholls, D.G.1
  • 130
    • 77956319634 scopus 로고    scopus 로고
    • Calcium-dependent mitochondrial function and dysfunction in neurons
    • Pivovarova, N. B. & Andrews, S. B. Calcium-dependent mitochondrial function and dysfunction in neurons. FEBS J. 277, 3622-3636 (2010).
    • (2010) FEBS J , vol.277 , pp. 3622-3636
    • Pivovarova, N.B.1    Andrews, S.B.2
  • 132
    • 80052627393 scopus 로고    scopus 로고
    • 2+-dependent apoptosis and necrosis
    • 2+-dependent apoptosis and necrosis. Cell Calcium 50, 222-233 (2011).
    • (2011) Cell Calcium , vol.50 , pp. 222-233
    • Rasola, A.1    Bernardi, P.2
  • 133
    • 0033570890 scopus 로고    scopus 로고
    • 3-linked mitochondrial calcium signals
    • DOI 10.1093/emboj/18.22.6349
    • 3-linked mitochondrial calcium signals. EMBO J. 18, 6349-6361 (1999). (Pubitemid 29533239)
    • (1999) EMBO Journal , vol.18 , Issue.22 , pp. 6349-6361
    • Szalai, G.1    Krishnamurthy, R.2    Hajnoczky, G.3
  • 134
    • 0037087782 scopus 로고    scopus 로고
    • 2+ and sustained opening of the permeability transition pore
    • 2+ and sustained opening of the permeability transition pore. J. Cell Sci. 11 5, 1175-1188 (2002). (Pubitemid 34272482)
    • (2002) Journal of Cell Science , vol.115 , Issue.6 , pp. 1175-1188
    • Jacobson, J.1    Duchen, M.R.2
  • 135
    • 84857579110 scopus 로고    scopus 로고
    • Slow calcium waves and redox changes precede mitochondrial permeability transition pore opening in the intact heart during hypoxia and reoxygenation
    • Davidson, S. M., Yellon, D. M., Murphy, M. P. & Duchen, M. R. Slow calcium waves and redox changes precede mitochondrial permeability transition pore opening in the intact heart during hypoxia and reoxygenation. Cardiovasc. Res. 93, 445-453 (2012).
    • (2012) Cardiovasc. Res. , vol.93 , pp. 445-453
    • Davidson, S.M.1    Yellon, D.M.2    Murphy, M.P.3    Duchen, M.R.4
  • 137
    • 57349160257 scopus 로고    scopus 로고
    • Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria
    • Cereghetti, G. M. et al. Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria. Proc. Natl Acad. Sci. USA 105, 15803-15808 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 15803-15808
    • Cereghetti, G.M.1
  • 138
    • 34848840991 scopus 로고    scopus 로고
    • Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death
    • DOI 10.1038/sj.embor.7401062, PII 7401062
    • Cribbs, J. T. & Strack, S. Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death. EMBO Rep. 8, 939-944 (2007). (Pubitemid 47500477)
    • (2007) EMBO Reports , vol.8 , Issue.10 , pp. 939-944
    • Cribbs, J.T.1    Strack, S.2
  • 140
    • 33745934410 scopus 로고    scopus 로고
    • Which came first, the cytochrome c release or the mitochondrial fission?
    • DOI 10.1038/sj.cdd.4401985, PII 4401985
    • Martinou, J. C. & Youle, R. J. Which came first, the cytochrome c release or the mitochondrial fission? Cell Death Differ. 13, 1291-1295 (2006). (Pubitemid 44057462)
    • (2006) Cell Death and Differentiation , vol.13 , Issue.8 , pp. 1291-1295
    • Martinou, J.-C.1    Youle, R.J.2
  • 141
    • 0034610995 scopus 로고    scopus 로고
    • 2+ influx in Bcl-2-overexpressing cells
    • 2+ influx in Bcl-2-overexpressing cells. J. Cell Biol. 148, 857-862 (2000).
    • (2000) J. Cell Biol. , vol.148 , pp. 857-862
    • Pinton, P.1
  • 142
    • 0035355341 scopus 로고    scopus 로고
    • 2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: Significance for the molecular mechanism of Bcl-2 action
    • DOI 10.1093/emboj/20.11.2690
    • 2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action. EMBO J. 20, 2690-2701 (2001). (Pubitemid 32938554)
    • (2001) EMBO Journal , vol.20 , Issue.11 , pp. 2690-2701
    • Pinton, P.1    Ferrari, D.2    Rapizzi, E.3    Di Virgilio, F.4    Pozzan, T.5    Rizzuto, R.6
  • 146
    • 69149093396 scopus 로고    scopus 로고
    • Intramitochondrial calcium regulation by the FHIT gene product sensitizes to apoptosis
    • Rimessi, A. et al. Intramitochondrial calcium regulation by the FHIT gene product sensitizes to apoptosis. Proc. Natl Acad. Sci. USA 106, 12753-12758 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 12753-12758
    • Rimessi, A.1
  • 153
    • 70149105706 scopus 로고    scopus 로고
    • The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor
    • Rong, Y. P. et al. The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor. Proc. Natl Acad. Sci. USA 106, 14397-14402 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 14397-14402
    • Rong, Y.P.1
  • 154
    • 47349089719 scopus 로고    scopus 로고
    • Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals
    • Rong, Y. P. et al. Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals. Mol. Cell 31, 255-265 (2008).
    • (2008) Mol. Cell , vol.31 , pp. 255-265
    • Rong, Y.P.1
  • 162
    • 67549135655 scopus 로고    scopus 로고
    • The inositol 1, 4, 5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1
    • Vicencio, J. M. et al. The inositol 1, 4, 5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1. Cell Death Differ. 16, 1006-1017 (2009).
    • (2009) Cell Death Differ , vol.16 , pp. 1006-1017
    • Vicencio, J.M.1
  • 164
    • 77955041880 scopus 로고    scopus 로고
    • 2+ transfer to mitochondria
    • 2+ transfer to mitochondria. Cell 142, 270-283 (2010).
    • (2010) Cell , vol.142 , pp. 270-283
    • Cardenas, C.1
  • 165
    • 77952759763 scopus 로고    scopus 로고
    • Role of inositol trisphosphate receptors in autophagy in DT40 cells
    • Khan, M. T. & Joseph, S. K. Role of inositol trisphosphate receptors
    • (2010) J. Biol. Chem. , vol.285 , pp. 16912-16920
    • Khan, M.T.1    Joseph, S.K.2
  • 166
    • 82855169506 scopus 로고    scopus 로고
    • 2+ signaling and autophagy induction are interrelated
    • 2+ signaling and autophagy induction are interrelated. Autophagy 7, 1472-1489 (2011).
    • (2011) Autophagy , vol.7 , pp. 1472-1489
    • Decuypere, J.P.1
  • 167
    • 0017119234 scopus 로고
    • 2+-binding glycoprotein
    • 2+-binding glycoprotein. Nature 264, 185-186 (1976).
    • (1976) Nature , vol.264 , pp. 185-186
    • Panfili, E.1
  • 168
  • 169
    • 79958730981 scopus 로고    scopus 로고
    • Single channel characterization of the mitochondrial ryanodine receptor in heart mitoplasts
    • Ryu, S. Y., Beutner, G., Kinnally, K. W., Dirksen, R. T. & Sheu, S. S. Single channel characterization of the mitochondrial ryanodine receptor in heart mitoplasts. J. Biol. Chem. 286, 21324-21329 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 21324-21329
    • Ryu, S.Y.1    Beutner, G.2    Kinnally, K.W.3    Dirksen, R.T.4    Sheu, S.S.5
  • 171
    • 55549110813 scopus 로고    scopus 로고
    • UCPs-unlikely calcium porters
    • Brookes, P. S. et al. UCPs-unlikely calcium porters. Nature Cell Biol. 10, 1235-1237 (2008).
    • (2008) Nature Cell Biol , vol.10 , pp. 1235-1237
    • Brookes, P.S.1
  • 172
    • 80052756138 scopus 로고    scopus 로고
    • 2+-ATPase (SERCA) by decreasing mitochondrial ATP production
    • 2+-ATPase (SERCA) by decreasing mitochondrial ATP production. J. Biol. Chem. 286, 32533-32541 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 32533-32541
    • De Marchi, U.1    Castelbou, C.2    Demaurex, N.3
  • 174
    • 37849038285 scopus 로고    scopus 로고
    • LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability
    • Dimmer, K. S. et al. LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability. Hum. Mol. Genet. 17, 201-214 (2008).
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 201-214
    • Dimmer, K.S.1
  • 175
    • 0021868401 scopus 로고
    • The stoichiometry of the exchange catalysed by the mitochondrial calcium/sodium antiporter
    • Brand, M. D. The stoichiometry of the exchange catalysed by the mitochondrial calcium/sodium antiporter. Biochem. J. 229, 161-166 (1985). (Pubitemid 15068128)
    • (1985) Biochemical Journal , vol.229 , Issue.1 , pp. 161-166
    • Brand, M.D.1
  • 176
    • 47249162028 scopus 로고    scopus 로고
    • 2+ handing suggests a 3: 1 stoichiometry
    • DOI 10.1113/jphysiol.2008.151977
    • 2+ handling suggests a 3:1 stoichiometry. J. Physiol. 586, 3267-3285 (2008). (Pubitemid 351984705)
    • (2008) Journal of Physiology , vol.586 , Issue.13 , pp. 3267-3285
    • Dash, R.K.1    Beard, D.A.2


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